MicroRNA-331 and microRNA-151-3p as biomarkers in patients with ST-segment elevation myocardial infarction.

abstract：:The symmetrically stable craniofacial bony structure supports the complex functions and delicate contour of the face. Congenital craniofacial deformities are often accompanied by bony defects and have been repetitively correlated with compromised dento-maxillary stability, but neither the extent nor the pattern of cle...

journal_title：Scientific reports

authors： Luo X,Huang H,Yin X,Shi B,Li J

更新日期：2019-03-12 00:00:00

abstract：:Control of nonlinear large-scale dynamical networks, e.g., collective behavior of agents interacting via a scale-free connection topology, is a central problem in many scientific and engineering fields. For the linear version of this problem, the so-called controllability Gramian has played an important role to quanti...

journal_title：Scientific reports

authors： Kashima K

更新日期：2016-06-06 00:00:00

abstract：:The complex phase transitions of vanadium dioxide (VO2) have drawn continual attention for more than five decades. Dynamically, ultrafast electron diffraction (UED) with atomic-scale spatiotemporal resolution has been employed to study the reaction pathway in the photoinduced transition of VO2, using bulk and strain-f...

journal_title：Scientific reports

authors： He X,Punpongjareorn N,Liang W,Lin Y,Chen C,Jacobson AJ,Yang DS

更新日期：2017-08-30 00:00:00

abstract：:The glycocalyx regulates the interaction of mammalian cells with extracellular molecules, such as cytokines. However, it is unknown to which extend the glycocalyx of distinct cancer cells control the binding and uptake of nanoparticles. In the present study, exome sequencing data of cancer patients and analysis of dis...

journal_title：Scientific reports

authors： von Palubitzki L,Wang Y,Hoffmann S,Vidal-Y-Sy S,Zobiak B,Failla AV,Schmage P,John A,Osorio-Madrazo A,Bauer AT,Schneider SW,Goycoolea FM,Gorzelanny C

更新日期：2020-12-31 00:00:00

abstract：:Protein structure prediction is a grand challenge. Prediction of protein structures via the representations using backbone dihedral angles has recently achieved significant progress along with the on-going surge of deep neural network (DNN) research in general. However, we observe that in the protein backbone angle pr...

journal_title：Scientific reports

authors： Mataeimoghadam F,Newton MAH,Dehzangi A,Karim A,Jayaram B,Ranganathan S,Sattar A

更新日期：2020-11-10 00:00:00

abstract：:The ability of human metaphase-II arrested eggs to activate following fertilisation declines with advancing maternal age. Egg activation is triggered by repetitive increases in intracellular Ca(2+) concentration ([Ca(2+)]i) in the ooplasm as a result of sperm-egg fusion. We therefore hypothesised that eggs from older ...

journal_title：Scientific reports

authors： Haverfield J,Nakagawa S,Love D,Tsichlaki E,Nomikos M,Lai FA,Swann K,FitzHarris G

更新日期：2016-01-20 00:00:00

abstract：:Fairly poor data are available on the relationship between taste perception, food preferences and oral microbiota. In the present study, we investigated the hypothesis that subjects with higher responsiveness to 6-n-propylthiuracil (PROP) might be characterized by a different taste sensitivity and tongue microbiota co...

journal_title：Scientific reports

authors： Cattaneo C,Gargari G,Koirala R,Laureati M,Riso P,Guglielmetti S,Pagliarini E

更新日期：2019-03-05 00:00:00

abstract：:Harmaline (HAR), a natural occurrence β-carboline alkaloid, was isolated from the seeds of Peganum harmala and exhibited potent antitumor effect. In this study, the anti-gastric tumor effects of HAR were firstly investigated in vitro and in vivo. The results strongly showed that HAR could inhibit tumor cell proliferat...

journal_title：Scientific reports

authors： Wang Y,Wang C,Jiang C,Zeng H,He X

更新日期：2015-12-18 00:00:00

abstract：:Toll-like receptors (TLRs), as innate immunity sensors, play critical roles in immune responses. Six SNPs of TLR3, TLR7, and TLR8 were genotyped to determine their associations with systemic lupus erythematosus (SLE) and clinical manifestations of SLE. TLR7 SNP rs3853839 was independently associated with SLE susceptib...

journal_title：Scientific reports

authors： Wang CM,Chang SW,Wu YJ,Lin JC,Ho HH,Chou TC,Yang B,Wu J,Chen JY

更新日期：2014-01-21 00:00:00

abstract：:A method is proposed to drive an ultrafast non-adiabatic dynamics of an ultracold gas trapped in a time-dependent box potential. The resulting state is free from spurious excitations associated with the breakdown of adiabaticity, and preserves the quantum correlations of the initial state up to a scaling factor. The p...

journal_title：Scientific reports

authors： del Campo A,Boshier MG

更新日期：2012-01-01 00:00:00

abstract：:Leprosy remains persistently endemic in several low- or middle income countries. Transmission is still ongoing as indicated by the unabated rate of leprosy new case detection, illustrating the insufficiency of current prevention methods. Therefore, low-complexity tools suitable for large scale screening efforts to spe...

journal_title：Scientific reports

authors： van Hooij A,Tjon Kon Fat EM,Batista da Silva M,Carvalho Bouth R,Cunha Messias AC,Gobbo AR,Lema T,Bobosha K,Li J,Weng X,Salgado CG,Spencer JS,Corstjens PLAM,Geluk A

更新日期：2018-12-18 00:00:00

abstract：:The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required. In order to identify new candidates as potential drug targets, we combined large-scale transposon mutagenesis data analysis and bioinforma...

journal_title：Scientific reports

authors： Fernández-Piñar R,Lo Sciuto A,Rossi A,Ranucci S,Bragonzi A,Imperi F

更新日期：2015-12-01 00:00:00

abstract：:It has been recently ascribed to several inflammatory cytokines (i.e. TGF-β3, TNF-α, and IL-1) a functional role in regulating Sertoli cell blood-testis barrier (BTB) dynamics. In the testis, IL-6 inhibits meiotic DNA synthesis during the seminiferous epithelium cycle, reduces sperm motility and influences the secreti...

journal_title：Scientific reports

authors： Zhang H,Yin Y,Wang G,Liu Z,Liu L,Sun F

更新日期：2014-03-03 00:00:00

abstract：:Accumulating evidence indicates the association between obesity and lung function. However, no previous study has examined whether obesity affects lung function in normal weight participants with high body fat. We hypothesized that subjects with normal weight obesity (NWO) were inversely associated with lung function ...

journal_title：Scientific reports

authors： Chen YY,Kao TW,Fang WH,Wang CC,Chang YW,Yang HF,Wu CJ,Sun YS,Chen WL

更新日期：2019-06-20 00:00:00

abstract：:Invasive plant species often form dense mono-dominant stands in areas they have invaded, while having only sparse distribution in their native ranges, and the reasons behind this phenomenon are a key point of research in invasive species biology. Differences in species composition between native and invasive ranges ma...

journal_title：Scientific reports

authors： Zheng Y,Liao Z

更新日期：2017-11-22 00:00:00

abstract：:Mitochondria distribution in cells controls cellular physiology in health and disease. Here we describe the mitochondrial morphology and positioning found in the different stages of the lytic cycle of the eukaryotic single-cell parasite Toxoplasma gondii. The lytic cycle, driven by the tachyzoite life stage, is respon...

journal_title：Scientific reports

authors： Ovciarikova J,Lemgruber L,Stilger KL,Sullivan WJ,Sheiner L

更新日期：2017-02-16 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Reslova N,Huvarova V,Hrdy J,Kasny M,Kralik P

更新日期：2019-04-04 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL, lipocalin 2 or LCN2) is an iron carrier protein whose circulating level is increased by kidney injury, bacterial infection and obesity, but its metabolic consequence remains elusive. To study physiological role of LCN2 in energy homeostasis, we challenged female Lcn2 k...

journal_title：Scientific reports

authors： Ishii A,Katsuura G,Imamaki H,Kimura H,Mori KP,Kuwabara T,Kasahara M,Yokoi H,Ohinata K,Kawanishi T,Tsuchida J,Nakamoto Y,Nakao K,Yanagita M,Mukoyama M,Mori K

更新日期：2017-11-14 00:00:00

abstract：:Global temperature changes have emphasized the need to understand how species adapt to thermal stress across their ranges. Genetic mechanisms may contribute to variation in thermal tolerance, providing evidence for how organisms adapt to local environments. We determine physiological thermal limits and characterize ge...

journal_title：Scientific reports

authors： Pimsler ML,Oyen KJ,Herndon JD,Jackson JM,Strange JP,Dillon ME,Lozier JD

更新日期：2020-10-13 00:00:00

abstract：:Parametric analysis of Cerebellar Ataxia (CA) could be of immense value compared to its subjective clinical assessments. This study focuses on a comprehensive scheme for objective assessment of CA through the instrumented versions of 9 commonly used neurological tests in 5 domains- speech, upper limb, lower limb, gait...

journal_title：Scientific reports

authors： Kashyap B,Phan D,Pathirana PN,Horne M,Power L,Szmulewicz D

更新日期：2020-06-11 00:00:00

abstract：:Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...

journal_title：Scientific reports

authors： Matsumoto H,Hoshino J,Arai Y,Mukai R,Nakamura K,Kikuchi Y,Kishi S,Akiyama H

更新日期：2020-11-11 00:00:00

abstract：:Little is known about circulating biomarkers of vascular injury in relation to cardiovascular disease risk. Thus, we evaluated associations between six novel markers (E-Selectin, P-Selectin, thrombomodulin, thrombopoietin, intercellular adhesion molecule 3 and GPIIb/IIIa) and established cardiovascular risk factors as...

journal_title：Scientific reports

authors： Pletsch-Borba L,Grafetstätter M,Hüsing A,González Maldonado S,Kloss M,Groß ML,Johnson T,Sookthai D,Bugert P,Kaaks R,Kühn T

更新日期：2019-02-28 00:00:00

abstract：:Bone homeostasis is maintained by the balance of osteoblasts (OBs) and osteoclasts (OCs). Increased activity of OCs not only contributes to pathological bone resorption, such as osteoporosis and periodontitis, but also is responsible for physiological conditions like orthodontic tooth movement (OTM). However, the deta...

journal_title：Scientific reports

authors： Guo T,Zhang L,Konermann A,Zhou H,Jin F,Liu W

更新日期：2015-01-26 00:00:00

abstract：:Bats are the only mammals capable of true, powered flight, which drives an extremely high metabolic rate. The "Free Radical Theory of Ageing" (FTRA) posits that a high metabolic rate causes mitochondrial heteroplasmy and the progressive ageing phenotype. Contrary to this, bats are the longest-lived order of mammals gi...

journal_title：Scientific reports

authors： Jebb D,Foley NM,Whelan CV,Touzalin F,Puechmaille SJ,Teeling EC

更新日期：2018-09-11 00:00:00

abstract：:Animal models are indispensible to investigate the pathogenesis and treatments of non-alcoholic fatty liver diseases (NAFLD). Altered cholesterol metabolism has been implicated into the pathogenesis of NAFLD. Here, using high fat, cholesterol and cholate diet (HFHC), we generated a novel tree shrew (Tupaia belangeri c...

journal_title：Scientific reports

authors： Zhang L,Zhang Z,Li Y,Liao S,Wu X,Chang Q,Liang B

更新日期：2015-11-02 00:00:00

abstract：:Polarization of macrophages is regulated through complex signaling networks. Correlating miRNA and mRNA expression over time after macrophage polarization has not yet been investigated. We used paired RNA-Seq and miRNA-Seq experiments to measure the mRNA and miRNA expression in bone marrow-derived macrophages over a t...

journal_title：Scientific reports

authors： Lu L,McCurdy S,Huang S,Zhu X,Peplowska K,Tiirikainen M,Boisvert WA,Garmire LX

更新日期：2016-12-16 00:00:00

abstract：:Understanding the traits that might be linked with biological invasions represents a great challenge for preventing non-target effects on local biodiversity. In predatory insects, the ability to exploit habitats for oviposition and the physiological response to prey availability differs between species. Those species ...

journal_title：Scientific reports

authors： Rondoni G,Ielo F,Ricci C,Conti E

更新日期：2017-06-16 00:00:00

abstract：:To assess differences between secondary high myopia (SHM) due to congenital glaucoma and primary high myopia (PHM) and non-highly myopic eyes (NHM) in the relationships between axial length and Bruch's membrane (BM) thickness and retinal pigment epithelium (RPE) density. The histomorphometric study included human glob...

journal_title：Scientific reports

authors： Jonas JB,Li D,Holbach L,Panda-Jonas S

更新日期：2020-03-20 00:00:00

abstract：:Light regulates cGMP concentration in the photoreceptor cytoplasm by activating phosphodiesterase (PDE) molecules through a G-protein signalling cascade. Spontaneous PDE activity is present in rod outer segments even in darkness. This basal PDE activity (βdark) has not been determined in wild type mammalian photorecep...

journal_title：Scientific reports

authors： Turunen TT,Koskelainen A

更新日期：2019-02-04 00:00:00

abstract：:We describe here a partial skull with associated mandible of a large felid from Monte Argentario, Italy (Early Pleistocene; ~1.5 million years). Propagation x-ray phase-contrast synchrotron microtomography of the specimen, still partially embedded in the rock matrix, allows ascribing it reliably to Acinonyx pardinensi...

journal_title：Scientific reports

authors： Cherin M,Iurino DA,Zanatta M,Fernandez V,Paciaroni A,Petrillo C,Rettori R,Sardella R

更新日期：2018-05-29 00:00:00