Pharmacokinetic evaluation of MFF in combinations with tacrolimus and cyclosporine. Findings of C0 and AUC.

abstract：:This study aimed to investigate the correlation of long noncoding RNA zinc finger antisense 1 (lncRNA ZFAS1) expression with disease risk, disease severity and inflammatory cytokines levels in lumbar disc degeneration (LDD) patients.83 LDD patients underwent surgery and 28 traumatized, non-LDD patients underwent lumba...

journal_title：Medicine

authors： Deng RY,Hong T,Li CY,Shi CL,Liu C,Jiang FY,Li J,Fan XM,Feng SB,Wang YF

更新日期：2019-12-01 00:00:00

abstract：RATIONALE:Coronavirus disease 2019 (COVID-19), now a global pandemic, has spread to a large number of countries around the world. Symptoms of COVID-19 can range from mild to severe, including fever, cough, shortness of breath, and pneumonia. Some cases even remain asymptomatic. Data regarding the epidemiological and cl...

journal_title：Medicine

authors： Liu Q,Zhang Y,Long Y

更新日期：2020-08-14 00:00:00

abstract：:Primary cutaneous aspergillosis (PCA) is an uncommon infection of the skin. There is a paucity of organized literature regarding this entity in regard to patient characteristics, associated Aspergillus species, and treatment modalities on outcome (disease recurrence, disease dissemination, and mortality).We reviewed a...

journal_title：Medicine

authors： Tatara AM,Mikos AG,Kontoyiannis DP

更新日期：2016-06-01 00:00:00

abstract：:To evaluate the predictive and prognostic significance of the prognostic nutritional index (PNI) in a large cohort of gastric cancer patients who underwent gastrectomy.Assessing a patient's immune and nutritional status, PNI has been reported as a predictive marker for surgical outcomes in various types of cancer.We r...

journal_title：Medicine

authors： Lee JY,Kim HI,Kim YN,Hong JH,Alshomimi S,An JY,Cheong JH,Hyung WJ,Noh SH,Kim CB

更新日期：2016-05-01 00:00:00

abstract：:Since body fatness is a convincing risk factor for endometrial cancer, dietary fat intake was speculated to be associated with endometrial cancer risk. However, epidemiological studies are inconclusive. We aimed to conduct a meta-analysis to assess the associations between dietary fat intake and endometrial cancer ris...

journal_title：Medicine

authors： Zhao J,Lyu C,Gao J,Du L,Shan B,Zhang H,Wang HY,Gao Y

更新日期：2016-07-01 00:00:00

abstract：:Mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) presents different clinical presentations from that with other lesions (OL). It is significant to investigate the neural mechanism underlying the different clinical presentations using neuroimaging study.Thirty mTLE patients with mTLE-HS, 30 mTLE patie...

journal_title：Medicine

authors： Wei W,Zhang Z,Xu Q,Yang F,Sun K,Lu G

更新日期：2016-03-01 00:00:00

abstract：:The aim of this study was to compare bone mineral densities (BMDs) and body composition between Southeast Asia college students and Chinese college students, in order to provide a certain reference enhancing college students' physical fitness.A total of 1694 Chinese college students (294 men and 1400 women, aged 18-22...

journal_title：Medicine

authors： Liu P,Ye Z,Lu J,Lu H,Guan L,Teng Z,Gao S,Li M

更新日期：2016-09-01 00:00:00

abstract：:This retrospective study compared efficacy and safety of fludarabine combined with intermediate-dose cytarabine (FA regimen) versus high-dose cytarabine (HiDAC regimen) as consolidation therapy in acute myeloid leukemia (AML) patients who achieved complete remission. Disease-free survival (DFS) and overall survival (O...

journal_title：Medicine

authors： Zhang W,Ding Y,Wu H,Chen Y,Lu H,Chen C,Fu J,Wang W,Liang A,Zou S

更新日期：2014-12-01 00:00:00

abstract：:The objective of this study was to assess the frequency of comorbidities and multimorbidities in rheumatoid arthritis (RA) patients under biologic therapy and their effects on biological disease modifying antirheumatic drugs (DMARDs) choice, timing, and response.Hacettepe University Biologic Registry (HUR-BIO) is sing...

journal_title：Medicine

authors： Armagan B,Sari A,Erden A,Kilic L,Erdat EC,Kilickap S,Kiraz S,Bilgen SA,Karadag O,Akdogan A,Ertenli I,Kalyoncu U

更新日期：2018-03-01 00:00:00

abstract：:Chronic hepatitis B (CHB) remains a global health problem. Therapeutic vaccination has been successfully employed to treat a subpopulation of CHB patients. Personalized treatment can not only improve therapeutic efficacy, but also decrease the cost of medical care. Since microRNAs (miRNAs) are highly conserved and are...

journal_title：Medicine

authors： Wang W,Li J,Zhang X,Wen Y,Wang XY,Yuan Z

更新日期：2016-01-01 00:00:00

abstract：:Young children with olfactory disturbance are sometimes encountered in ENT clinics. We investigated the clinical applicability of olfactory testing to the pediatric population in China.One hundred and ninety-three healthy children aged 6 to 17 years were enrolled. All participants were asked for demographic informatio...

journal_title：Medicine

authors： Chen G,Pan H,Li L,Wang J,Zhang D,Wu Z

更新日期：2018-04-01 00:00:00

abstract：:Irreversible electroporation (IRE) is a new nonthermal tumor ablation modality that induces apoptosis in the treated tissue without affecting collagen. Its use is particularly indicated for tumors involving major structures, such as encompassed or infiltrated vessels and/or ducts, which need to be preserved and hinder...

journal_title：Medicine

authors： Trueba-Arguiñarena FJ,de Prado-Otero DS,Poves-Alvarez R

更新日期：2015-07-01 00:00:00

abstract：:The hyperimmunoglobulin E recurrent-infection syndrome (HIE) entails a disorder of recurrent bacterial infections of the skin and sinopulmonary tract commencing in infancy or early childhood in the presence of serum levels of IgE which are at least 10 times normal (greater than 2,000 IU/ml). Variable concomitants of H...

journal_title：Medicine

authors： Donabedian H,Gallin JI

更新日期：1983-07-01 00:00:00

abstract：INTRODUCTION:Pneumonia is one of the most important characteristics of coronavirus disease 2019 (COVID-19) and imaging findings of COVID-19 pneumonia are diverse and change over disease course. However, the detailed clinical course of organizing pneumonia (OP) caused by COVID-19 has not been clarified. PATIENT CONCERN...

journal_title：Medicine

authors： Okamori S,Lee H,Kondo Y,Akiyama Y,Kabata H,Kaneko Y,Ishii M,Hasegawa N,Fukunaga K

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:Healthcare workers (HCWs) were at the frontline during the battle against coronavirus. Understanding and managing their fears and anxieties may hold lessons for handling future outbreaks. However, the experiences and perceptions risk of HCWs from coronavirus still remains to be controversial. Thus, the objec...

journal_title：Medicine

authors： Chen P,Lei J,Chen F,Zhou B

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Uveitis is the most common extra-articular manifestation in patients with ankylosing spondylitis (AS). The prevalence and characteristics of uveitis in AS have been studied in previous literatures, whereas its associated risk factors have not been clarified. Therefore, this study analyzed the risk factors of...

journal_title：Medicine

authors： Sun L,Wu R,Xue Q,Wang F,Lu P

更新日期：2016-07-01 00:00:00

abstract：INTRODUCTION:Carcinoid tumor is one of the most frequent neuroendocrine tumors, and the majority of which are usually observed in the lungs and gastrointestinal tract. The prevalence of ovarian carcinoids is merely 0.1% in ovarian neoplasms and 1% in carcinoid tumors. We described 2 rare cases in our hospital of primar...

journal_title：Medicine

authors： Zhai LR,Zhang XW,Yu T,Jiang ZD,Huang DW,Jia Y,Cui MH

更新日期：2020-10-02 00:00:00

abstract：:Revision total hip arthroplasty (THA) may cause intra- and postoperative massive bleeding. This prospective observational study evaluated if the maximum clot firmness of FIBTEM (MCFFIB) could act as a predictor of perioperative massive bleeding in revision THA.Fifty-eight adult patients undergoing revision THA were in...

journal_title：Medicine

authors： Shin HJ,Min BH,Na HS

更新日期：2018-06-01 00:00:00

abstract：RATIONALE:Pernicious anemia (PA) is an autoimmune gastritis that results from the destruction of gastric parietal cells and the associated lack of an intrinsic factor to bind ingested vitamin B12. While an association between PA and various liver diseases has been rarely reported, reports of associated diseases include...

journal_title：Medicine

authors： Yan X,Gao R,Hu Y,Jin J

更新日期：2018-09-01 00:00:00

abstract：RATIONALE:Cisplatin monotherapy-induced cardiotoxicity is rare, and the prevalence remains unknown. It's extremely important to stop cisplatin when cardiotoxicity is considered. PATIENT CONCERNS:A 53-year-old woman developed cervical cancer. She was administered cisplatin (37 mg/m/wk) for 3 weeks, but the left ventric...

journal_title：Medicine

authors： Hu Y,Sun B,Zhao B,Mei D,Gu Q,Tian Z

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Knee osteoarthritis (KOA) is a disabling joint disease with an increasingly prevalence among the older individuals. Tai Chi, one of the ancient meditative movements, has been recognized to have clinical benefits for KOA. We aim to evaluate the efficacy and safety of Tai Chi for patients with KOA through this...

journal_title：Medicine

authors： Ren R,Tang G,Tang C,Zhang J,Xiao X,Zhang Q

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Pharmacologic angiotensin axis blockade (AAB) has been associated with profound hypotension following anesthetic induction with propofol. To combat this problem, investigators have attempted to withhold angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) preoperatively, or...

journal_title：Medicine

authors： Bonavia A,Verbeek T,Adhikary S,Kunselman A,Budde A,Lyn-Sue J,Mets B

更新日期：2019-02-01 00:00:00

abstract：:This study aimed to assess the efficacy and safety of bevacizumab plus preoperative chemotherapy as first-line treatment for liver-only metastatic colorectal cancer in Chinese patients compared with those of preoperative chemotherapy alone.Patients with histologically confirmed liver-only metastatic colorectal cancer ...

journal_title：Medicine

authors： Lu ZH,Peng JH,Wang FL,Yuan YF,Jiang W,Li YH,Wu XJ,Chen G,Ding PR,Li LR,Kong LH,Lin JZ,Zhang RX,Wan DS,Pan ZZ

更新日期：2016-08-01 00:00:00

abstract：RATIONALE:Takayasu arteritis is a rare large vessel systemic vasculitis that predominantly affects the aorta and its main branches in women of childbearing age. Due to nonspecific symptoms during the acute phase of disease, early diagnosis is still a challenge for pediatricians. PATIENT CONCERNS:We reported a 3-month-...

journal_title：Medicine

authors： Liu H,Sun L,Upadhyaya RS,Chen Y,Ajoje OO

更新日期：2018-10-01 00:00:00

abstract：RATIONALE:Sodium valproate (VPA) and lamotrigine (LTG) are widely used antiepileptic drugs, disabling postural, and action tremors after using LTG with VPA were reported in 1993. However, in this study, we describe a patient in whom disabling resting-type tremor induced by 2-year use of VPA and LTG. PATIENT CONCERNS:A...

journal_title：Medicine

authors： He ZF,Chen J,Zhou CN,Rao Z,Wang XH

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:The primary objective of this study was to investigate whether dexmedetomidine could potentiate the analgesic efficacy of ropivacaine, when added to ropivacaine for wound infiltration in patients undergoing open gastrectomy. METHODS:Fifty patients scheduled for open gastrectomy were divided into 2 equal gro...

journal_title：Medicine

authors： Luan H,Zhu P,Zhang X,Tian L,Feng J,Wu Y,Yan Y,Zhao Z,Gu X

更新日期：2017-09-01 00:00:00

abstract：:The aim of the present study was to investigate the age-related patterns and the relationships between serum levels of tartrate-resistant acid phosphatase-5b (TRACP-5b) or bone-specific alkaline phosphatase (BAP), and the heel stiffness index measured by quantitative ultrasound (QUS) in 429 Japanese men, with special ...

journal_title：Medicine

authors： Nishimura T,Arima K,Abe Y,Kanagae M,Mizukami S,Okabe T,Tomita Y,Goto H,Horiguchi I,Aoyagi K

更新日期：2018-02-01 00:00:00

abstract：:Cerebral edema is a frequent and serious complication in traumatic brain injury (TBI) patients. The objective is to study the effect of dexamethasone in patients with brain contusions, and to assess its effect on the vasogenic component of the pericontusional edema.Prospective-observational study to quantify, using ma...

journal_title：Medicine

authors： Moll A,Lara M,Pomar J,Orozco M,Frontera G,Llompart-Pou JA,Moratinos L,González V,Ibáñez J,Pérez-Bárcena J

更新日期：2020-10-23 00:00:00

abstract：:Nonurgent emergency department (ED) patients are a controversial issue in the era of ED overcrowding. However, a substantial number of post-ED hospitalizations were found, which prompted for investigation and strategy management. The objective of this study is to identify risk factors for predicting the subsequent hos...

journal_title：Medicine

authors： Ng CJ,Liao PJ,Chang YC,Kuan JT,Chen JC,Hsu KH

更新日期：2016-06-01 00:00:00

abstract：:Human infection with avian influenza A virus (H7N9) is a concern because of the mortality rate. Previously, we characterized immunological responses during active infection with it and reported evidence of impaired antigen-presenting capability, particularly in severely affected individuals. Here we describe an invest...

journal_title：Medicine

authors： Chen J,Cui G,Lu C,Ding Y,Gao H,Zhu Y,Wei Y,Wang L,Uede T,Li L,Diao H

更新日期：2016-02-01 00:00:00