Abstract:
RATIONALE:Takayasu arteritis is a rare large vessel systemic vasculitis that predominantly affects the aorta and its main branches in women of childbearing age. Due to nonspecific symptoms during the acute phase of disease, early diagnosis is still a challenge for pediatricians. PATIENT CONCERNS:We reported a 3-month-old girl who presented with sustained elevated levels of acutephase reactants, which could not be explained by infectious diseases and malignant diseases. DIAGNOSES:The patient's angiography showed dilatation, stenosis, and inflammation of the aorta and its branches and was diagnosed as Takayasu arteritis. INTERVENTIONS:We prescribed glucocorticoids combined with immunosuppressive agents, which include cyclophosphamide used as an induction drug for 6 months, and mycophenolate mofetil used as a maintenance drug. Glucocorticoids gradually stopped. OUTCOMES:At present, the girl went into clinical remission with normal levels of acute-phase reactants and improvement of vascular inflammation demonstrated by angiography. LESSONS:This case report illustrates that Takayasu arteritis can occur in children at a very early age after birth before apparent clinical symptoms.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Liu H,Sun L,Upadhyaya RS,Chen Y,Ajoje OOdoi
10.1097/MD.0000000000012637subject
Has Abstractpub_date
2018-10-01 00:00:00pages
e12637issue
41eissn
0025-7974issn
1536-5964pii
00005792-201810120-00032journal_volume
97pub_type
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