Abstract:
:Osteocalcin (OC) is an endocrine hormone that regulates glucose metabolism.The aim of this study was to investigate the relationship between serum OC levels and glucose metabolism after trauma.This was a retrospective study of trauma patients admitted to the Department of Emergency Medicine between October 2017 and April 2019. Age, height, weight, injury severity score, and previous medical history were recorded. Serum N-terminal mid-fragment of OC (N-MID OC), hemoglobin Alc (HbA1c), fasting plasma glucose (FPG), fasting insulin (FINS), C-peptide, and other biochemical indicators were measured. Differences between the HbA1c-L (HbA1c <6.5%) and HbA1c-H (HbA1c ≥6.5%) groups were compared. The association of N-MID OC with indicators of glucose metabolism was analyzed.Out of 394 trauma patients, leukocyte and FPG levels in the HbA1c-H group (n = 93) were higher (P < .05), while N-MID OC levels were lower (P = .011) than the HbA1c-L group (n = 301). N-MID OC was negatively correlated with HbA1c in the total population (r = -0.273, P < .001) as well as in the HbA1c-L (r = -0.289, P < .001) and HbA1c-H (r = -0.390, P < 0.001) groups, and was positively correlated with C-peptide in the HbA1c-H group (r = 0.395, P < .001). The different quartiles in the HbA1c-L showed that N-MID OC declined with increasing HbA1c, which was higher than N-MID OC levels in the HbA1c-H group. Multiple linear regression analysis revealed that serum HbA1c was independently associated with serum OC levels after trauma (β=-1.608, P < .001).This study strongly suggests the importance of serum OC on glucose metabolism in trauma patients. HbA1c is independently associated with serum OC levels.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Yang Y,Zhong W,Huang J,Geng L,Feng Qdoi
10.1097/MD.0000000000021901subject
Has Abstractpub_date
2020-09-04 00:00:00pages
e21901issue
36eissn
0025-7974issn
1536-5964pii
00005792-202009040-00032journal_volume
99pub_type
杂志文章相关文献
MEDICINE文献大全abstract::Traditional Chinese medicine tongue diagnosis can mirror the status of the internal organ, but evidence is lacking regarding the accuracy of tongue diagnosis to gastroesophageal reflux disease (GERD). This study was to investigate the association between GERD and tongue manifestation, and whether tongue imaging could ...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000020471
更新日期:2020-07-17 00:00:00
abstract::The prognostic significance of systemic atherothrombosis in heart failure (HF) with preserved ejection fraction (HFpEF) remains unclear. This study aimed to investigate the relation between the presence of polyvascular disease (PVD) and cardiovascular outcomes in HFpEF patients.A total of 510 consecutive HFpEF patient...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015959
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Coronary heart disease angina pectoris is a common clinical symptom in patients with coronary heart disease, due to coronary atherosclerotic stenosis or sputum leading to coronary insufficiency, myocardial transient ischemia, hypoxia caused by precordial pain as the main clinical manifestations Group syndrom...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018548
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Undiagnosed pleural effusions (UPEs) are a common problem of respiratory medicine, leading to an increased diagnostic burden globally. However, the most efficient and cost-effective approaches to UPEs remain controversial. This study aimed to assess the diagnostic value of ultrasound-guided nee...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000021076
更新日期:2020-07-02 00:00:00
abstract::Portal vein thrombosis (PVT) might impair the prognosis of cirrhotic patients. However, formation of de novo PVT after transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients without preexisting PVT was rarely reported. Moreover, it is not known whether warfarin is efficient in preventing de novo PV...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018737
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Post-treatment alpha-fetoprotein (AFP) response has been reported to be associated with prognosis of hepatocellular carcinoma (HCC) patients, but the results were not consistent. This meta-analysis aimed to explore the relationship between AFP response and clinical outcomes of HCC. METHODS:PubMed, Embase, M...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016557
更新日期:2019-08-01 00:00:00
abstract:RATIONALE:Multiple primary malignancies can occur in the same organ or in multiple organs or systems. Likewise, they can occur simultaneously or successively. Based on the timing of the diagnosis, they are classified as multiple synchronous (i.e., concurrent) or metachronous (i.e., successive) primary malignancies. The...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011107
更新日期:2018-06-01 00:00:00
abstract::Fetal cardiovascular malformations is widely focused and screened, but the accuracy of screening is not satisfactory. In this study, we compared the types of congenital heart malformation, accompanying diseases and fetal outcomes in the first and second trimesters of pregnancy to clarify the advantage of early screeni...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016822
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION:Acute hydrocephalus is a common complication of spontaneous or traumatic intracranial bleeding with extensive subarachnoid hemorrhage (SAH) or ventricular extension. However, it has never been reported to be secondary to pneumocephalus. PATIENT CONCERNS:A 32-year-old man was admitted following a motorcycl...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018654
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Tuberculosis (TB) is the leading cause of health complications and death among human with immunodeficiency virus (HIV) infection. When TB develops during pregnancy or the early postpartum period, it is associated with negative maternal, pregnancy, and fetus and infant outcome, including premature birth, low ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023089
更新日期:2020-11-20 00:00:00
abstract::Management of large tissue defects resulting from local wide resection of perianal is a clinical challenge for surgeons. The aim of the present study was to investigate the efficacy of negative pressure wound therapy (NPWT) following skin grafting on perianal surgical wound healing.Included in this study were 12 patie...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004670
更新日期:2016-08-01 00:00:00
abstract::[An uncorrected version of "Comparative Effectiveness of Different Oral Antibiotics Regimens for Treatment of Urinary Tract Infection in Outpatients: An Analysis of National Representative Claims Database" was originally posted in Volume 93, Issue 28 of Medicine. The article has since been corrected and reposted in th...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000460804.00343.a0
更新日期:2015-01-01 00:00:00
abstract:RATIONALE:Castleman disease (CD) is a rare lymphoproliferative disease with a poorly understood etiology. The occurrence of CD in the abdominal cavity is very rare, especially in the retroperitoneal peripancreatic region. PATIENT CONCERNS:A 33-year-old woman was referred to our department on March 1, 2018 for a detail...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019515
更新日期:2020-03-01 00:00:00
abstract:RATIONALE:The incidence of severe hyperandrogenism associated with masculinity in women is very low. While rare and difficult to diagnose, androgen secreting tumors should be suspected in women with hyperandrogenism and hirsutism, especially in the postmenopausal population. Herein we present one case of ovarian Leydig...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010093
更新日期:2018-03-01 00:00:00
abstract::While older age associates with adverse percutaneous coronary intervention (PCI) outcomes, detailed information relating age to stent strut coverage and neointimal characteristics is lacking. One hundred nineteen patients with 123 sirolimus-eluting stents (SESs) were divided into 3 groups: group A (≤55 years), group B...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002246
更新日期:2015-12-01 00:00:00
abstract:RATIONALE:It is largely unknown about the tumor growth of breast cancer naturally. We devised and analyzed an appropriate mathematical tool of the equations that describe how fast tumors grow without treatment on the basis of the ellipsoid shape of solid breast cancer. PATIENT CONCERNS:A 31-year-old woman presented wi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017659
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:This study will specifically investigate the effect of butylphthalide on hemodynamics in patients with watershed stroke (WS). METHODS:We will search the following databases from their inceptions to the March 1, 2020: Cochrane Library, MEDLINE, EMBASE, PsycINFO, Web of Science, Cumulative Index to Nursing an...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000020151
更新日期:2020-05-01 00:00:00
abstract::In view of the forthcoming long-acting antiretrovirals, measures should be taken to prevent the selection of HIV drug resistance mutations. All subjects who had been switched to boosted protease inhibitors plus maraviroc (bPIs/MVC) with baseline HIV-1 RNA >50 copies/mL between June, 2014, and April, 2015, were retrosp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005728
更新日期:2017-02-01 00:00:00
abstract:RATIONALE:Isolated metastasis to the hand bones is very rare. Only seven cases of metastasis to the trapezium have been reported. To the best of our knowledge, this is the first report of a single metastasis to the trapezium from a gastric adenocarcinoma. PATIENT CONCERNS:A 62-year-old man presented with pain and mass...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009294
更新日期:2017-12-01 00:00:00
abstract::Calcific tendinitis (CT) of the shoulder is a painful disorder usually identified in individuals aged 40 and 60 years. The estimated global prevalence of CT is 2.7% to 36%. We examined the association of hyperlipidemia and sex with CT of the shoulder using Taiwan Biobank (TWB) and the National Health Insurance Researc...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023299
更新日期:2020-11-13 00:00:00
abstract::The aim of this study was to investigate the correlation between cluster of differentiation 86 (CD86) gene rs1129055 and rs2715267 single nucleotide polymorphisms and sepsis susceptibility.One hundred twenty-five sepsis patients and 120 healthy controls were enrolled in this case-control study. CD86 polymorphisms rs11...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017482
更新日期:2019-10-01 00:00:00
abstract::We carried out a prospective study of 530 patients older than 14 years of age with brucellosis. We describe the incidence and clinical features of the focal forms of the disease, analyzing some of the possible factors associated with their appearance. One hundred sixty-nine patients (31.9%) had a focal form or complic...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-199607000-00003
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Infant hip screening for early detection of developmental dysplasia of the hip (DDH) is essential as early detection can enable less invasive treatments and achieve better long-term results. A previous meta-analysis assessed about 10,000 infants per group, which is insufficient for evaluating the effect of d...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000023562
更新日期:2020-12-11 00:00:00
abstract::Hysterectomy is a potential risk factor for subsequent surgery for pelvic organ prolapse, especially when the prolapse exists before hysterectomy. Women without prolapse before hysterectomy may also experience prolapse after hysterectomy. This study aimed to describe a surgical modification of laparoscopic colposuspen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014616
更新日期:2019-02-01 00:00:00
abstract::Electromyographic biofeedback (EMG-BF) therapy provides information on the state of contraction of the targeted muscles and relaxation of their antagonists, which can facilitate early active range of motion (RoM) after elbow surgery. Our aim in this study was to calculate the minimum detectable change (MDC) during EMG...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021889
更新日期:2020-08-21 00:00:00
abstract::The aims of this study were to investigate the incidence and risk factors for oral candidiasis in patients receiving radiotherapy for head and neck cancer, and to determine the influence of topical steroid therapy on the development of oral candidiasis.We conducted a retrospective study of 300 patients receiving radio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013073
更新日期:2018-11-01 00:00:00
abstract:RATIONALE:Collecting duct carcinoma (CDC) is a rare type of nonclear renal cell carcinoma, often presenting at an advanced stage of the disease, and standard treatment guidelines have not been established. PATIENT CONCERNS:A 73-year-old man was admitted to our hospital with complaints of fever and lower right back pai...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013173
更新日期:2018-11-01 00:00:00
abstract::The relevance of LP(a), Hcy, and D-D in ischemic cerebrovascular disease remains undefined. This study aimed to assess the associations of plasma LP(a), Hcy and D-D levels with the subtype of ischemic cerebrovascular disease.Patients with ischemic cerebrovascular disease admitted to the Taixing People's Hospital were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014910
更新日期:2019-03-01 00:00:00
abstract::Laparoscopic inguinal herniorrhaphy has been well established for the management of primary and recurrent inguinal hernias. Single-incision laparoscopic surgery (SILS) has now been accepted as a less invasive alternative to conventional laparoscopic surgery. However, commercially available access devices for SILS had ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021787
更新日期:2020-08-21 00:00:00
abstract:BACKGROUND:This research aims to assess the response to acid suppression therapy in gastroesophageal reflux disease (GERD)-related chronic laryngitis (CL). METHODS:Data were extracted from Web of Knowledge, Embase, and PubMed for English language article published up to March 2016. Pooled overall response rate (ORR) r...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000004868
更新日期:2016-10-01 00:00:00