Negative pressure wound therapy combined with skin grafting improves surgical wound healing in the perianal area.

Abstract:

:Management of large tissue defects resulting from local wide resection of perianal is a clinical challenge for surgeons. The aim of the present study was to investigate the efficacy of negative pressure wound therapy (NPWT) following skin grafting on perianal surgical wound healing.Included in this study were 12 patients with perianal tumors who received skin grafting after perianal tumor resection between December 2012 and December 2014. A self-designed negative pressure drainage device was then applied to maintain a standard negative pressure at -150 mm Hg and removed on day 8 postoperation. The outcome was recorded immediately after NPWT and at 6-month follow-up.All skin grafts survived without infection, hematoma, and necrosis in all 12 patients. No tumor recurrence was detected during 6-month follow-up. Natural folds were observed around the anus. All patients showed normal bowel movements.NPWT following skin grafting was effective for perianal surgical wound healing and infection prevention, thus benefiting anatomical and functional recovery of the anus.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Jia-Zi S,Xiao Z,Jun-Hui L,Chun-Yu X,Hong-da B

doi

10.1097/MD.0000000000004670

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

e4670

issue

35

eissn

0025-7974

issn

1536-5964

pii

00005792-201608300-00050

journal_volume

95

pub_type

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