Negative pressure wound therapy combined with skin grafting improves surgical wound healing in the perianal area.


:Management of large tissue defects resulting from local wide resection of perianal is a clinical challenge for surgeons. The aim of the present study was to investigate the efficacy of negative pressure wound therapy (NPWT) following skin grafting on perianal surgical wound healing.Included in this study were 12 patients with perianal tumors who received skin grafting after perianal tumor resection between December 2012 and December 2014. A self-designed negative pressure drainage device was then applied to maintain a standard negative pressure at -150 mm Hg and removed on day 8 postoperation. The outcome was recorded immediately after NPWT and at 6-month follow-up.All skin grafts survived without infection, hematoma, and necrosis in all 12 patients. No tumor recurrence was detected during 6-month follow-up. Natural folds were observed around the anus. All patients showed normal bowel movements.NPWT following skin grafting was effective for perianal surgical wound healing and infection prevention, thus benefiting anatomical and functional recovery of the anus.


Medicine (Baltimore)




Jia-Zi S,Xiao Z,Jun-Hui L,Chun-Yu X,Hong-da B




Has Abstract


2016-08-01 00:00:00
















  • The association of hypernatremia and hypertonic saline irrigation in hepatic hydatid cysts: A case report and retrospective study.

    abstract:RATIONALE:Hypernatremia is a rare but fatal complication of hypertonic saline (HS) irrigation in hepatic hydatid disease. It needs careful monitoring and treatment. PATIENT CONCERNS:A 28-year-old woman with hepatic hydatid cysts who received operation treatment developed electrolyte disturbances. We also conducted a r...


    pub_type: 杂志文章


    authors: Zeng R,Wu R,Lv Q,Tong N,Zhang Y

    更新日期:2017-09-01 00:00:00

  • Value of quantitative and qualitative analyses of circulating cell-free DNA as diagnostic tools for hepatocellular carcinoma: a meta-analysis.

    abstract::Qualitative and quantitative analyses of circulating cell-free DNA (cfDNA) are potential methods for the detection of hepatocellular carcinoma (HCC). Many studies have evaluated these approaches, but the results have been variable. This meta-analysis is the first to synthesize these published results and evaluate the ...


    pub_type: 杂志文章,meta分析


    authors: Liao W,Mao Y,Ge P,Yang H,Xu H,Lu X,Sang X,Zhong S

    更新日期:2015-04-01 00:00:00

  • Osteonecrosis of the femoral head, nonunion and potential risk factors in Pauwels grade-3 femoral neck fractures: A retrospective cohort study.

    abstract::The present study was to analyze clinical outcome of Pauwels grade-3 femoral neck fractures treated by different surgical techniques. Potential risk factors associated with nonunion and osteonecrosis of the femoral head (ONFH) were investigated as well. The retrospective study comprised of 67 sequential patients treat...


    pub_type: 杂志文章


    authors: Zhang YL,Chen S,Ai ZS,Gao YS,Mei J,Zhang CQ

    更新日期:2016-06-01 00:00:00

  • Cardiac septic pulmonary embolism: A retrospective analysis of 20 cases in a Chinese population.

    abstract::Based on the source of the embolus, septic pulmonary embolism (SPE) can be classified as cardiac, peripheral endogenous, or exogenous. Cardiac SPEs are the most common.We conducted a retrospective analysis of 20 patients with cardiac SPE hospitalized between 1991 and 2013 at a Chinese tertiary referral hospital.The st...


    pub_type: 杂志文章


    authors: Song XY,Li S,Cao J,Xu K,Huang H,Xu ZJ

    更新日期:2016-06-01 00:00:00

  • Delayed intracranial subdural empyema following burr hole drainage: Case series and literature review.

    abstract:RATIONALE:A subdural empyema (SDE) following burr hole drainage of a chronic subdural hematoma (CSDH) can be difficult to distinguish from a recurrence of the CSDH, especially when imaging data is limited to a computed tomography (CT) scan. PATIENTS CONCERNS:All patients underwent burr hole drainage of the CSDH at fir...


    pub_type: 杂志文章


    authors: Kim YS,Joo SP,Song DJ,Kim SH,Kim TS

    更新日期:2018-05-01 00:00:00

  • Comparison of 3 clinical models for predicting the probability of pulmonary embolism.

    abstract::Two clinical models have been described to predict the probability of pulmonary embolism: the Canadian (or Wells) model, and the Geneva model. A third model has been developed recently at our institution (the Pisa model). We compared the performance of the 3 models in 215 consecutive patients with suspected pulmonary ...


    pub_type: 杂志文章


    authors: Miniati M,Bottai M,Monti S

    更新日期:2005-03-01 00:00:00

  • Subthreshold micropulse laser photocoagulation therapy in a case of bilateral retinal astrocytic hamartomas with tuberous sclerosis complex: A case report.

    abstract:RATIONALE:Report a case of bilateral multiple retinal hamartomas (RAHs) in a patient with tuberous sclerosis complex (TSC) and introduced a new method (subthreshold micropulse laser photocoagulation) for the treatment of RAHs. PATIENT CONCERNS:A 20-year-old man with TSC complained of decreased vision and metamorphosia...


    pub_type: 杂志文章


    authors: Yan S,Chen Y,Chen R,Tian B,Li Z

    更新日期:2018-12-01 00:00:00

  • Sedentary behaviors in children and adolescents with type 1 diabetes, depending on the insulin therapy used.

    abstract::Assessment of sedentary behaviors in children and adolescents with type 1 diabetes (T1D), relative to the method of insulin therapy used, and in comparison to healthy controls.The study group consisted of 215 children with T1D, including 109 (50.7%) insulin pen and 106 (49.3%) insulqsain pump users. The control group ...


    pub_type: 杂志文章


    authors: Czenczek-Lewandowska E,Leszczak J,Weres A,Baran J,Wyszyńska J,Grzegorczyk J,Lewandowski B,Mazur A

    更新日期:2019-05-01 00:00:00

  • Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke: A systematic review and meta-analysis.

    abstract:BACKGROUND:The receptor for advanced glycosylation end products (RAGE) has been widely linked to diabetic atherosclerosis, but its effects on coronary artery disease (CAD) and ischemic stroke (IS) remain controversial. The Gly82Ser polymorphism is located in the ligand-binding V domain of RAGE, suggesting a possible in...


    pub_type: 杂志文章,meta分析,评审


    authors: Ma WQ,Qu QR,Zhao Y,Liu NF

    更新日期:2016-12-01 00:00:00

  • Clinical analysis of prenatal ultrasound diagnosis of fetal cardiovascular malformations in the first and second trimesters of pregnancy: A CARE-compliant article.

    abstract::Fetal cardiovascular malformations is widely focused and screened, but the accuracy of screening is not satisfactory. In this study, we compared the types of congenital heart malformation, accompanying diseases and fetal outcomes in the first and second trimesters of pregnancy to clarify the advantage of early screeni...


    pub_type: 杂志文章


    authors: Han B,Li Y,Tang Y,Qu X,Wang F,Song H,Xu Y

    更新日期:2019-08-01 00:00:00

  • Dacryocystitis secondary to neglected silicone tube in lacrimal duct for 10 years: A case report.

    abstract:INTRODUCTION:Contracture of dacryocyst by an implanted lacrimal silicone tube is rare. This report describes a unique case of secondary dacryocystitis and the contracture of dacryocyst caused by a lacrimal silicone tube that was placed in the lacrimal system for 10 years. PATIENT CONCERNS:A 63-year-old female was diag...


    pub_type: 杂志文章


    authors: Li L,Lai Z,Huang W,Xu F,Wu Y

    更新日期:2020-11-06 00:00:00

  • Impact of neurological diseases on family planning: A single-center experience.

    abstract::This cross-sectional study aimed to assess the impact of epilepsy, myasthenia gravis (MG), and multiple sclerosis (MS) on pregnancy and family planning decision-making in a cohort of Saudi women. Women with epilepsy, MG, and MS were recruited consecutively at the time of their follow-up visits at a neurology clinic. D...


    pub_type: 杂志文章


    authors: Alanazy MH,Asiri A,Edrees MF,Abuzinadah AR

    更新日期:2020-10-30 00:00:00

  • Erratum: The Value of U/S to Determine Priority for Upper Gastrointestinal Endoscopy in Emergency Room: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000002241.]. ...


    pub_type: 已发布勘误



    更新日期:2016-01-08 00:00:00

  • Timing of surgical ligation and morbidities in very low birth weight infants.

    abstract::The present study examined whether early patent ductus arteriosus (PDA) surgical ligation at ≤2 weeks of life was associated with increased morbidities and mortality in very low birth weight infants (VLBWIs) who were diagnosed with hemodynamically significant (hs) PDA. Between December 2013 and December 2015, a total ...


    pub_type: 杂志文章


    authors: Youn Y,Moon CJ,Lee JY,Lee C,Sung IK

    更新日期:2017-04-01 00:00:00

  • Risk factors for bone flap resorption after autologous bone cranioplasty: Protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:One of the most common complications following autologous cranioplasty is bone flap resorption (BFR). Severe BFR can lead to revision surgery with implantation of synthetic bone flap and also necessarily lead to higher hospital expenses. This study aims to perform a meta-analysis to summarize available evide...


    pub_type: 杂志文章


    authors: Yang J,Sun T,Yuan Y,Li X,Zhou Y,Guan J

    更新日期:2020-07-10 00:00:00

  • The influence of blood pressure patterns on renal outcomes in patients with chronic kidney disease: The long-term follow up result of the APrODiTe-2 study.

    abstract::Blood pressure (BP) control is the most established practice for preventing the progression and complications of chronic kidney disease (CKD). We examined the influence of BP patterns on target organ damage in hypertensive patients with CKD by using long-term follow-up data of the APrODiTe-2 study.We collected 5 years...


    pub_type: 杂志文章,多中心研究


    authors: Cha RH,Lee H,Lee JP,Kim YS,Kim SG

    更新日期:2020-02-01 00:00:00

  • Pharmacokinetic evaluation of MFF in combinations with tacrolimus and cyclosporine. Findings of C0 and AUC.

    abstract::We hypothesized that area under the concentration time curve (AUC(0-12)) is more accurate pharmacokinetic predictor vs trough level of mycophenolic acid (C0).Study was performed at the University Hospital of Limoges (France) and included 238 renal recipients aged 22 to 82 years. Risk of nephropathy was evaluated by an...


    pub_type: 杂志文章


    authors: Radzevičienė A,Stankevičius E,Saint-Marcoux F,Marquet P,Maslauskienë R,Kaduševičius E

    更新日期:2020-03-01 00:00:00

  • Paraproteinemic keratopathy in monoclonal gammopathy of undetermined significance treated with primary keratoprosthesis: Case report, histopathologic findings, and world literature review.

    abstract:RATIONALE:We report a case of paraproteinemic keratopathy associated with monoclonal gammopathy of undetermined significance, treated with keratoprosthesis as a primary penetrating procedure. Histopathological findings and a world literature review are presented. PATIENT CONCERNS:A 74 year old female recently diagnose...


    pub_type: 杂志文章,评审


    authors: Chiang HH,Wieland RS,Rogers TS,Gibson PC,Atweh G,McCormick G

    更新日期:2017-12-01 00:00:00

  • Focal nodular hyperplasia on an accessory liver lobe: A case report and literature review.

    abstract:INTRODUCTION:Accessory liver lobe (ALL), an autonomous island of normal liver parenchyma, is a rare congenital anomaly that is difficult for preoperative diagnosis and often identified incidentally. It can also be accompanied with benign or malignant diseases, which is extremely rare. There are only 3 cases of focal no...


    pub_type: 杂志文章,评审


    authors: Su N,Chen C,Dai Q,Wang L,Yang M,Xia Y,Jiang Y,Lv K

    更新日期:2020-07-24 00:00:00

  • Hedgehog Signaling in Pancreatic Fibrosis and Cancer.

    abstract::The hedgehog signaling pathway was first discovered in the 1980s. It is a stem cell-related pathway that plays a crucial role in embryonic development, tissue regeneration, and organogenesis. Aberrant activation of hedgehog signaling leads to pathological consequences, including a variety of human tumors such as pancr...


    pub_type: 杂志文章,评审


    authors: Bai Y,Bai Y,Dong J,Li Q,Jin Y,Chen B,Zhou M

    更新日期:2016-03-01 00:00:00

  • Association between high-density lipoprotein cholesterol and renal function in elderly hypertension: a cross-sectional study in Chinese population.

    abstract::Few studies have yet investigated the possible association between high-density lipoprotein cholesterol (HDL-C) and kidney function in elderly patients with primary hypertension. Accordingly, the aim of the present study was to evaluate the relationship between HDL-C and kidney function in elderly hypertension. A tota...


    pub_type: 杂志文章


    authors: Zhang YP,Lu MG,Duan DD,Liu YL,Liu M,Li Y,Kuang ZM,Lu Y,Liu X,Li XH,Yuan H

    更新日期:2015-04-01 00:00:00

  • Three inherited disorders of calcium sensing.

    abstract::Three distinct disorders of calcium homeostasis can result from mutations in the gene encoding the human calcium-sensing receptors (CASR; MIM 145980). One form of autosomal dominant familial hypocalciuric hypercalcemia results from the heterozygous state of inactivating mutations in the CASR gene. Neonatal severe hype...


    pub_type: 杂志文章,评审


    authors: Pollak MR,Seidman CE,Brown EM

    更新日期:1996-05-01 00:00:00

  • Cardiac malignant peripheral nerve sheath tumor on computed tomography and magnetic resonance imaging: A case report.

    abstract:RATIONALE:Malignant peripheral nerve sheath tumor (MPNST) is a very rare sarcoma of the heart, and few cases have been reported. Herein, we retrospectively reviewed clinical manifestations, imaging features and management of our patient and other reported cases. PATIENT CONCERNS:A 32-year-old woman was referred to the...


    pub_type: 杂志文章


    authors: Li S,Qiu Y,Yu J,Liang C,Peng L

    更新日期:2019-11-01 00:00:00

  • Analysis of the Fibrinogen and Neutrophil-Lymphocyte Ratio in Esophageal Squamous Cell Carcinoma: A Promising Blood Marker of Tumor Progression and Prognosis.

    abstract::Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignancies in gastrointestinal tract cancers and even patients with early ESCC have a high metastatic potential. Difficulties are associated with clinically predicting tumor progression and prognosis based on conventional tumor markers determine...


    pub_type: 杂志文章


    authors: Arigami T,Okumura H,Matsumoto M,Uchikado Y,Uenosono Y,Kita Y,Owaki T,Mori S,Kurahara H,Kijima Y,Ishigami S,Natsugoe S

    更新日期:2015-10-01 00:00:00

  • Prediction of the outcome of bladder dysfunction based on electrically induced reflex findings in patients with cauda equina syndrome: A retrospective study.

    abstract::The evaluation of the electrically induced bulbocavernosus reflex (BCR) using electromyography (EMG) is a useful tool for evaluating the integrity of sacral spinal segments 2 to 4, and that of their afferent and efferent connections in the urogenital region. In the current retrospective study, the value of this techni...


    pub_type: 杂志文章


    authors: Lee DG,Kwak SG,Chang MC

    更新日期:2017-05-01 00:00:00

  • An unusual location of gouty panniculitis: A case report.

    abstract:RATIONALE:Gouty panniculitis, characterised by the deposition of monosodium urate crystals in subcutaneous tissue, is a rare clinical manifestation of gout. PATIENT CONCERNS:The case of a 67-year-old man is reported, who presented an erythematous nodule on the upper part of the right buttock suspicious for an abscess....


    pub_type: 杂志文章


    authors: Martin D,Joliat GR,Fournier P,Brunel C,Demartines N,Gié O

    更新日期:2017-04-01 00:00:00

  • Invasive aspergillosis. Clinical features of 35 proven cases at a single institution.

    abstract::Thirty-five patients with clinical features and histologically or microbiologically proven infection met predetermined stringent criteria for invasive aspergillosis over a 5-year period at our institution. Underlying conditions included hematologic malignancy, solid tumor, bone marrow and solid organ transplantation, ...


    pub_type: 杂志文章


    authors: Kaiser L,Huguenin T,Lew PD,Chapuis B,Pittet D

    更新日期:1998-05-01 00:00:00

  • Sudden seizure during cesarean section: A case report.

    abstract:RATIONALE:A first seizure can range from a fleeting subjective experience or a twitch (myoclonic jerk) through to a tonic-clonic convulsion. A first seizure occurred in a parturient during cesarean section is very rare. We describe the case of a parturient who suffered seizure when the fetus was delivered. PATIENT CON...


    pub_type: 杂志文章


    authors: Zhou W,Zhu Q

    更新日期:2018-12-01 00:00:00

  • Computed tomography-guided cryoablation for adrenal metastases: local control and survival.

    abstract::To evaluate the feasibility, local control, and survival after computed tomography (CT)-guided cryoablation for adrenal metastases.This study included 31 consecutive patients with adrenal metastases who were treated by CT-guided cryoablation in our center from July 2011 to October 2017. The technical success rate, loc...


    pub_type: 杂志文章


    authors: Zhang W,Sun LJ,Xu J,Fu YF,Zhuang ZX

    更新日期:2018-12-01 00:00:00

  • Comparative Assessment of the Anticoagulant Activity of Rivaroxaban and Dabigatran in Patients With Nonvalvular Atrial Fibrillation: A Noninterventional Study.

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    pub_type: 杂志文章


    authors: Tsantes AE,Kyriakou E,Ikonomidis I,Katogiannis K,Papadakis I,Douramani P,Kopterides P,Kapsimali V,Lekakis J,Tsangaris I,Bonovas S

    更新日期:2016-04-01 00:00:00