Abstract:
:Human T lymphotropic virus type 1 (HTLV-I) is a retrovirus which is prevalent in southern Japan, the Caribbean Basin, and Africa. Recent seroprevalence studies in the United States suggest that there are about 50,000 infected individuals. The identification of 5 individuals with HTLV-I-associated leukemia/lymphoma referred to our center with relatively limited screening methods suggests that these disorders are more common than currently appreciated. Though 99% of infected individuals remain asymptomatic, this virus may cause immunosuppression, lymphomas, or myelopathy. The lymphomas have been classified as acute or chronic forms of adult T cell leukemia-lymphoma (ATLL). Acute ATLL is a T cell form of non-Hodgkin's lymphoma in an HTLV-I-infected individual with leukemia, skin infiltration, or hypercalcemia. This disorder is poorly responsive to chemotherapy and all patients should be referred for experimental protocols. Chronic ATLL is an insidious disease characterized by lymphadenopathy, skin infiltration of less than 10% of the body surface, and/or atypical lymphocytes with highly convoluted nuclei which include 1 to 10% of the nucleated cells in the peripheral blood, but no visceral involvement or hypercalcemia. The prognosis of these patients is not clearly defined. All individuals with mature T lymphocytic malignancies should be evaluated with HTLV-I-specific assays. The most sensitive and specific assays available include the enzyme linked immunoadsorbent antibody assay (ELISA) and the polymerase chain DNA amplification reaction assay. With improved laboratory techniques and greater awareness of the characteristics of this disease by clinicians, it is likely that the natural history of HTLV-I infection will be better defined, and improvements in therapeutic management will be developed.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Ratner L,Poiesz BJdoi
10.1097/00005792-198811000-00004subject
Has Abstractpub_date
1988-11-01 00:00:00pages
401-22issue
6eissn
0025-7974issn
1536-5964journal_volume
67pub_type
杂志文章,评审相关文献
MEDICINE文献大全abstract::The size of the elderly population and the incidence of papillary thyroid carcinoma (PTC) in this group appear to be rapidly increasing, although published information based on more detailed older age groupings are lacking.This study aimed to determine the clinical features and outcomes of elderly patients in PTC.All ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005450
更新日期:2016-11-01 00:00:00
abstract::We hypothesized that the objective treatment response of patients with diffuse large B-cell lymphoma (DLBCL) was affected by many factors such as pathophysiological, biological, and pharmaceutical mechanisms. This retrospective study aimed to evaluate the predictive significance of clinical prognostic factors and inte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002808
更新日期:2016-02-01 00:00:00
abstract::Recent advances in breast cancer management might make the use of postmastectomy radiotherapy (PMRT) redundant in the treatment of pT1/T2N1 patients. We investigated the impact of PMRT on disease-free survival (DFS) in these patients who have a low risk of locoregional recurrence (LRR) after contemporary multidiscipli...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001259
更新日期:2015-08-01 00:00:00
abstract::To explore the value of serum levels of CA125, platelet count (PLT), neutrophil-lymphocyte ratio (NLR), and modified CA125 markers CA125a and CA125b in predicting pelvic dense adhesion (PDA) associated with adenomyosis, CA125a = lg(CA125 × PLT × 10), CA125b = lg(CA125 × NLR).This retrospective study included 304 patie...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006880
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION:Diuretics are a commonly used for the treatment of acute pulmonary edema. However, inappropriate administration of diuretic drugs can result in clinical treatment failure and cause acute pulmonary edema. This is due to rapid decreases in intravascular volume as a result of diuretic treatment. To date, the ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019180
更新日期:2020-02-01 00:00:00
abstract::The impact of a publication in a particular medical area is reflected by the number of times the article is included as a citation. It is not known, however, which articles are cited the most in primary care journals. In our study, we aimed to identify the 100 most cited articles in primary care medicine and analyze t...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002219
更新日期:2015-12-01 00:00:00
abstract::This prospective cohort study was conducted to assess the duration of daytime napping and its effect combined with night sleep deprivation on the risk of developing high HOMA-IR (homeostasis model assessment of insulin resistance) index and disadvantageous changes in glycosylated hemoglobin (HbA1c) levels.A total of 5...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002734
更新日期:2016-02-01 00:00:00
abstract::The manometry with water-perfused or solid-state catheters is the predominant diagnostic procedure to detect motility disorders of the esophagus. Another method is the manometry using gas-perfused catheters. Although the high-resolution manometry is the method of first choice, the conventional manometry with helium ha...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009910
更新日期:2018-02-01 00:00:00
abstract::Melanoma, which is usually induced by ultraviolet light exposure and the following DNA damage, is the most dangerous skin cancer. The purpose of the present study was to screen key molecules involved in melanoma.Microarray data of E-MTAB-1862 were downloaded from the ArrayExpress database, which included 21 primary me...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007497
更新日期:2017-07-01 00:00:00
abstract::The aim of the study was to assess the independent contribution of hyperuricemia to coronary artery disease (CAD) confirmed by coronary angiography (CAG), and to explore associations between serum uric acid (SUA) level and CAD.We performed a retrospective cohort study of 5069 patients who underwent CAG. Patients were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012926
更新日期:2018-11-01 00:00:00
abstract:RATIONALE:Hemolymphangioma is a rare developmental defect of combined vasal and lymphatic vasculature. It is very rare that hemolymphangioma affects the bones and bladder simultaneously, and this condition has never been reported in PubMed. PATIENT CONCERNS:A 12-year-old male has a history of hospitalization for recur...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015213
更新日期:2019-04-01 00:00:00
abstract::There is still debate on whether high uric acid increases bone mineral density (BMD) against osteoporotic fracture or bone resorption caused by gout inflammation. This study aimed to evaluate whether gout offers a protective effect on bone health or not. We conducted a nationwide population-based retrospective cohort ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004669
更新日期:2016-08-01 00:00:00
abstract::Mastocytosis is a rare disease characterized by clonal neoplastic proliferation of mast cells (MCs). It ranges from skin lesions as cutaneous mastocytosis (CM) which may spontaneously regress to highly aggressive neoplasms with multiorgan involvement corresponding to some aggressive systemic mastocytosis (ASM), mast c...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010642
更新日期:2018-05-01 00:00:00
abstract::Nonmedical use of cough syrup (NUCS) among secondary vocational school (SVS) students has been an increasing concern for public health in China, but no data were available. This cross-sectional study aimed to investigate the epidemiological characters of NUCS as well as its risk factors among SVS students in China.Fro...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002969
更新日期:2016-03-01 00:00:00
abstract::Subcutaneous tissue is a rare site of metastasis, accounting for only 1-2% of all lung neoplasms. Positron emission tomography (PET) using ¹⁸F-fluorodeoxyglucose (FDG) has been reported to increase the diagnostic accuracy of subcutaneous metastasis. A 58-year-old woman presented with complaints of dry coughing, in whi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000851
更新日期:2015-05-01 00:00:00
abstract::Donor organ shortage continues to limit the availability of liver transplantation, a successful and established therapy of end-stage liver diseases. Strategies to mitigate graft shortage include the utilization of marginal livers and recently ex-situ normothermic machine perfusion devices. A 59-year-old woman with cir...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003119
更新日期:2016-04-01 00:00:00
abstract::Esophageal cancer is a common malignant tumor of the digestive system with a high incidence and a poor prognosis. At the present, CT-based radiomics is providing more and more valuable information. However, the heterogeneity of the study and the poor repeatability of the texture feature parameters have limited its wid...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021470
更新日期:2020-08-07 00:00:00
abstract::Unilateral sagittal split fracture (USSF) of the C1 lateral mass (LM) has been recently recognized as a rare variant of C1 atlas fracture. To date, there has been no study to investigate whether radiologic criteria can be applied to determine the presence or absence of transverse atlantal ligament (TAL) injury in USSF...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017077
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:To compare the effect of selective laser trabeculoplasty (SLT) and travoprost on 24-hour IOP fluctuations in primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG). METHODS:Sixty eyes were included. Sixteen and 14 eyes of POAG patients were randomized to receive 360° SLT or 0.004% travoprost, ...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000006047
更新日期:2017-02-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000000510.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000484495.36196.d5
更新日期:2016-06-10 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002306.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000481354.70978.fe
更新日期:2016-03-03 00:00:00
abstract::The purpose of this study was to assess the impact of tumor burden on the survival of patients with pathologic T3N0M0 (pT3N0M0) esophageal squamous cell carcinoma (ESCC).A total of 84 patients with pathologic T3N0M0 ESCC treated with radical esophagectomy and 3-field lymphadenectomy (3-FL) from January 2008 to Decembe...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017637
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Dyslipidemia is a common disorder in systemic lupus erythematosus (SLE) patients. It is still inconclusive whether antimalarial drugs could affect the serum lipids in SLE patients, therefore we conducted a systematic review and meta-analysis of available data to address this issue. METHODS:We comprehensivel...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000015030
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION:Intramuscular hemangioma (IMH) is a rare congenital soft tissue tumor. Here, we report a case of IMH patient who had undergone several surgeries and other treatments that were all ineffective before he visited us. CLINICAL FINDINGS:This IMH patient was a 16-yearold male who was born with a tumor of unknow...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005939
更新日期:2017-01-01 00:00:00
abstract::Most of recurrent bladder carcinoma after partial cystectomy did not cause diagnostic difficulties for urologists, because of the appearance of typical papillary in ultrasonography or cystoscopy, and could be easily confirmed by tumor biopsy. Three patients, ages from 35 to 62 years, had undergone bladder sparing trea...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000898
更新日期:2015-06-01 00:00:00
abstract::Oral contraceptives (OCs) following induced abortion offer a reliable method to avoid repeated abortion. However, limited data exist supporting the effective use of OCs postabortion. We conducted this systematic review and meta-analysis in the present study reported immediate administration of OCs or combined OCs post...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000003825
更新日期:2016-07-01 00:00:00
abstract:RATIONALE:Sirenomelia is a rare congenital malformation that threatens fetal survivals. The cases in which twin with sirenomelia and chromosomal abnormality have been seldomly reported. We reported a dichorionic twin case in which one twin had sirenomelia, the other twin had a normal phenotype, and they had different c...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000024229
更新日期:2021-01-08 00:00:00
abstract::To compare the efficacy of curettage and bone grafting combined with elastic intramedullary nailing (EIN) vs curettage and bone grafting in the treatment of long bone cysts in children and to clarify the necessity of using EIN in the treatment of bone cysts.Sixty-two patients were involved in this study from Jan. 2009...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016152
更新日期:2019-06-01 00:00:00
abstract::Preoperative autologous blood donation is a well-established procedure to reduce the need for allogeneic blood transfusion. We hypothesized that coagulation activity is maintained in cold-stored whole blood, because the fundamental polymerization properties of fibrin are preserved.Fifty adult patients who underwent el...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017357
更新日期:2019-09-01 00:00:00
abstract::We aim to determine the incidence of malignancy after liver transplantation (LT) compared to general population. The records of patients who received LTs at our center from October 1989 and November 2012 were retrospectively reviewed. The standardized incidence ratio (SIR) of cancer in the patients was compared to gen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000310
更新日期:2014-12-01 00:00:00