CA125 modified by PLT and NLR improves the predictive accuracy of adenomyosis-derived pelvic dense adhesion.


:To explore the value of serum levels of CA125, platelet count (PLT), neutrophil-lymphocyte ratio (NLR), and modified CA125 markers CA125a and CA125b in predicting pelvic dense adhesion (PDA) associated with adenomyosis, CA125a = lg(CA125 × PLT × 10), CA125b = lg(CA125 × NLR).This retrospective study included 304 patients who underwent surgery for adenomyosis. Correlations of serum levels of CA125, PLT, NLR, and modified CA125 markers with adenomyosis-derived PDA were analyzed by Logistic regression. Receiver operating characteristic curve was applied to assess the utility of these parameters for predicting PDA.All the parameters including CA125, PLT, NLR, and modified CA125 markers were positively correlated with PDA (P < .05 or P < .01). More importantly, CA125a was more specific (85.03% vs. 83.00%) and more sensitive (47.56% vs. 47.47%) than CA125 alone for the prediction of PDA, and CA125b could also improve the predictive specificity of PDA (53.13% vs. 47.47%).Serum CA125, PLT, and NLR were all closely correlated with PDA in adenomyosis patients. CA125 modified by PLT and NLR could further improve the predictive accuracy of adenomyosis-derived PDA, thus providing more meaningful references for better-informed decisions about the mode of surgical access for the clinical treatment of adenomyosis.


Medicine (Baltimore)




Jiang C,Liu C,Guo J,Chen L,Luo N,Qu X,Yang W,Ren Q,Cheng Z




Has Abstract


2017-05-01 00:00:00
















  • Intravenous versus topical tranexamic acid in primary total hip replacement: A meta-analysis.

    abstract:BACKGROUND:As the prevalence of total hip arthroplasty (THA) is increasing, it is usually associated with considerable blood loss. Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip joint arthroplasty. But the best route of TXA administration continues to be controversial. So, we conducte...


    pub_type: 杂志文章,meta分析


    authors: Zhang P,Liang Y,Chen P,Fang Y,He J,Wang J

    更新日期:2016-12-01 00:00:00

  • Clinicopathological features, surgical treatments, and survival outcomes of patients with small bowel adenocarcinoma.

    abstract::To date, because of their rarity, the clinicopathological features and surgical outcomes of small bowel adenocarcinomas (SBAs) have been insufficiently explored. We evaluated the clinicopathological features and long-term outcomes of patients who underwent surgery for SBA.This retrospective study (from 1999 to 2016) e...


    pub_type: 杂志文章


    authors: Zhang S,Yuan W,Zhang J,Chen Y,Zheng C,Ma J,Jiang Q,Zhao Y,Xu Q,Wang C

    更新日期:2017-08-01 00:00:00

  • Risk of Peripheral Arterial Occlusive Disease in Patients With Systemic Lupus Erythematosus: A Nationwide Population-Based Cohort Study.

    abstract::Systemic lupus erythematosus (SLE) is associated with atherosclerosis, but the relationship between SLE and peripheral arterial occlusive disease (PAOD) remains unclear. We sought to investigate this relationship by comparing cardiovascular complications in patients with and without SLE.Data on patients from 2000 to 2...


    pub_type: 杂志文章


    authors: Chuang YW,Yu MC,Lin CL,Yu TM,Shu KH,Kao CH

    更新日期:2015-11-01 00:00:00

  • Hepatitis C Virus Infection Associated With an Increased Risk of Deep Vein Thrombosis: A Population-Based Cohort Study.

    abstract::The association between the hepatitis C virus (HCV) infection and the risk of myocardial infarction (MI) and stroke has been previously investigated. However, the association between the HCV infection and the risk of venous thromboembolism (VTE) has not been extensively discussed. Using the Longitudinal Health Insuran...


    pub_type: 杂志文章


    authors: Wang CC,Chang CT,Lin CL,Lin IC,Kao CH

    更新日期:2015-09-01 00:00:00

  • Clinical outcome after endoscopic submucosal dissection for early gastric cancer of absolute and expanded indication.

    abstract::This study evaluated the clinical outcome of endoscopic submucosal dissection (ESD) in minute submucosa (SM) invasion or undifferentiated early gastric cancer (EGC) and analyzed factors related to local recurrence after ESD.We retrospectively reviewed the chart of EGC patients, who underwent ESD at our tertiary hospit...


    pub_type: 杂志文章


    authors: Kim JS,Kang SH,Moon HS,Lee ES,Kim SH,Sung JK,Lee BS,Jeong HY

    更新日期:2017-04-01 00:00:00

  • Effect of cognitive-behavioral therapy with music therapy in reducing physics test anxiety among students as measured by generalized test anxiety scale.

    abstract:BACKGROUND:The study determined the effect of cognitive-behavioral therapy (CBT) with music in reducing physics test anxiety among secondary school students as measured by generalized test anxiety scale. METHODS:Pre-test post-test randomized control trial experimental design was adopted in this study. A total of 83 se...


    pub_type: 杂志文章,随机对照试验


    authors: Ugwuanyi CS,Ede MO,Onyishi CN,Ossai OV,Nwokenna EN,Obikwelu LC,Ikechukwu-Ilomuanya A,Amoke CV,Okeke AO,Ene CU,Offordile EE,Ozoemena LC,Nweke ML

    更新日期:2020-04-01 00:00:00

  • Chronic thromboembolic pulmonary hypertension as the first manifestation of nephrotic syndrome in a 12-year-old child.

    abstract:RATIONALE:Chronic thromboembolic pulmonary hypertension (CTEPH) is rare in children and determining the underlying etiologies is essential for treatment. Venous thromboembolism, a well-known complication in nephrotic syndrome (NS), always occurrs during the treatment in course of the disease. However, CTEPH as the firs...


    pub_type: 杂志文章


    authors: Ma F,Zhou K,Hua Y,Liu X,Duan H,Li Y,Wang C

    更新日期:2018-10-01 00:00:00

  • Use of susceptibility-weighted imaging in assessing ischemic penumbra: A case report.

    abstract:RATIONALE:The ischemic penumbra assessment is essential for the subsequent therapy and prediction of evolution in patients with acute ischemic infraction. Although controversial as a perfect equivalence to penumbra, perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch may predict the response to t...


    pub_type: 杂志文章


    authors: Wu X,Luo S,Wang Y,Chen Y,Liu J,Bai J,Feng J,Zhang H

    更新日期:2017-02-01 00:00:00

  • CT and PET/CT findings of primary pulmonary diffuse large B-cell lymphoma: One case report and literature review.

    abstract:RATIONALE:Primary pulmonary diffuse large B-cell lymphoma (PPL-DLBCL) is rare and its clinical manifestations lack specificity. In this report, we present one case of PPL-DLBCL with complete clinical and imaging data, including uncontrast-enhanced CT, contrast-enhanced CT, and positron emission tomography (PET)/CT. Pre...


    pub_type: 杂志文章,评审


    authors: Bai Y,Liang W

    更新日期:2017-11-01 00:00:00

  • Prevalence of vitamin D deficiency and insufficiency among 460,537 children in 825 hospitals from 18 provinces in mainland China.

    abstract::This study was conducted to estimate the 25-hydroxyvitamin D (25 (OH)D) levels and explore factors related to vitamin D deficiency/insufficiency. This was a multicenter, hospital-based, cross-sectional observational study. Children admitted to hospitals for health examination were included for vitamin D measurement an...


    pub_type: 杂志文章,多中心研究


    authors: Yang C,Mao M,Ping L,Yu D

    更新日期:2020-10-30 00:00:00

  • Poorer prognosis in patients with advanced gastric squamous cell carcinoma compared with adenocarcinoma of the stomach: Case report.

    abstract:RATIONALE:Primary squamous cell carcinoma (SCC) of the stomach is a rare disease. The pathogenesis and prognosis of advanced SCC remains to be elucidated. The aim of the current study was to investigate the prognosis of recurrent or metastatic SCC of the stomach. PATIENT CONCERNS:A retrospective study examined the cli...


    pub_type: 杂志文章


    authors: Meng Y,Zhang J,Wang H,Zhang Y,Sun R,Zhang Z,Gao F,Huang C,Zhang S

    更新日期:2017-12-01 00:00:00

  • Arthroscopy versus nonoperative treatment of symptomatic femoroacetabular impingement syndrome: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Presently, hip arthroscopy is a widely adopted surgical intervention for the treatment of femoroacetabular impingement (FAI). However, there is insufficient evidence regarding which between arthroscopy and nonoperative treatment is more optimal for symptomatic FAI. METHODS:MEDLINE, Embase, Web of Science, a...


    pub_type: 杂志文章


    authors: Kim CH,Moon JK,Yoon JY,Lee S,Kim WJ,Kim HS,Lee SJ,Yoon PW

    更新日期:2020-12-04 00:00:00

  • A rare case of deep cerebral venous thrombosis secondary to traumatic epidural hematoma: Case report.

    abstract:RATIONALE:Deep cerebral venous thrombosis (DCVT) is a rare disease, but always results in poor prognosis. PATIENT CONCERNS:We reported a 79-year-old female with coma after traumatic brain injury (TBI). DIAGNOSIS:The epidural hematoma was first diagnosed on non-contrast computerized tomography (CT). The hypodense area...


    pub_type: 杂志文章


    authors: Zheng H,Xu W,Chen Y,Gai S,Chen G

    更新日期:2018-09-01 00:00:00

  • The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis.

    abstract:BACKGROUND:To comprehensively evaluate the treatment efficacy and safety of silymarin for patients with glucose/lipid metabolic dysfunction using a meta-analysis. METHODS:A systematic literature search in PubMed, EMBASE and Cochrane Library databases was performed up to October 1, 2019. STATA 13.0 software was used to...


    pub_type: 杂志文章,meta分析


    authors: Xiao F,Gao F,Zhou S,Wang L

    更新日期:2020-10-02 00:00:00

  • Negative impact of preoperative platelet-lymphocyte ratio on outcome after hepatic resection for intrahepatic cholangiocarcinoma.

    abstract::The elevated platelet-to-lymphocyte ratio (PLR), determined using an easy blood test based on platelet and lymphocyte counts, is reported to be a predictor of poor survival in patients with several cancers. The prognostic role of preoperative PLR in patients with intrahepatic cholangiocarcinoma (ICC) has, until now, b...


    pub_type: 杂志文章


    authors: Chen Q,Dai Z,Yin D,Yang LX,Wang Z,Xiao YS,Fan J,Zhou J

    更新日期:2015-04-01 00:00:00

  • Ultrasound follow-up of spontaneous tears of the plantar fascia treated with conservative therapies: Two case reports.

    abstract:RATIONALE:The plantar fascia (PF) is an important anatomical structure that stabilizes the longitudinal arch of the foot. While plantar fasciitis is a common pathology affecting the foot, tears of the PF are uncommon injuries characterized by acute pain in the plantar aspect of the foot. The main purpose of this paper ...


    pub_type: 杂志文章


    authors: Cocco G,Ricci V,Boccatonda A,Abate M,Guagnano MT,Schiavone C

    更新日期:2019-12-01 00:00:00

  • Left lung hypoplasia with a right tuberculous pleural effusion after childbirth: A case report.

    abstract:RATIONALE:Unilateral hypoplasia of the lung is a rare congenital condition, the mechanism of which is poorly understood. Primary pulmonary hypoplasia occurring in an adult is extremely rare and we present what is probably the first case of a link to a tuberculous pleural effusion in a young woman after childbirth. PAT...


    pub_type: 杂志文章


    authors: Lin S,Guan W,LaZhou C,Shi Y

    更新日期:2018-05-01 00:00:00

  • The effect of radionuclide solution volume on the detection rate of salivary aspiration in the radionuclide salivagram: A STROBE-compliant retrospective study.

    abstract::Despite the possibility that the methodological difference of this salivagram may influence the results for detection rate, there has been no study on the effect of the solution volume on detection rate. Moreover, to date, since the introduction of the nucleotide salivagram, there has been a tendency that a constant s...


    pub_type: 杂志文章


    authors: Lee DH,Kim JM,Lee Z,Park D

    更新日期:2018-07-01 00:00:00

  • Large dosage Huangqin (Scutellaria) and Huanglian (Rhizoma Coptidis) for T2DM: A protocol of systematic review and meta-analysis of randomized clinical trials.

    abstract:INTRODUCTION:Type 2 diabetes mellitus (T2DM) is a metabolic disease with widespread concern in the world. It has the characteristics of high incidence rate and high disability rate, which seriously affects economic and social development. large dose herb Rhizoma Coptidis (Huanglian) and Scutellaria (Huangqin) or compou...


    pub_type: 杂志文章,meta分析


    authors: Huang X,Wang L,Yue R,Ding N,Yang H

    更新日期:2020-09-18 00:00:00

  • Analysis of the Metabolic and Structural Brain Changes in Patients With Torture-Related Post-Traumatic Stress Disorder (TR-PTSD) Using ¹⁸F-FDG PET and MRI.

    abstract::Many people exposed to torture later suffer from torture-related post-traumatic stress disorder (TR-PTSD). The aim of this study was to analyze the morphologic and functional brain changes in patients with TR-PTSD using magnetic resonance imaging (MRI) and positron emission tomography (PET). This study evaluated 19 su...


    pub_type: 杂志文章


    authors: Zandieh S,Bernt R,Knoll P,Wenzel T,Hittmair K,Haller J,Hergan K,Mirzaei S

    更新日期:2016-04-01 00:00:00

  • Endovascular treatment with stenting of celiac artery aneurysms.

    abstract::This study aimed to detail the clinical outcomes of patients suffering from celiac arterial aneurysm (CAA) that underwent treatment via stent occlusion.This is a single-center, retrospective study. A total of 8 consecutive CAA patients were treated via stent occlusion from March 2014 to September 2018 at our hospital....


    pub_type: 杂志文章


    authors: Yuan FK,Xi HL,Qin RH,Tian ZL,Li C,Lu F

    更新日期:2020-11-25 00:00:00

  • Familial isolated hypoparathyroidism: a molecular genetic analysis of 8 families with 23 affected persons.

    abstract::Abnormalities in the parathyroid hormone (PTH) gene as a cause of hypoparathyroidism were evaluated by linkage analysis with DNA polymorphisms adjacent to the PTH gene in 8 families in which members were affected with familial isolated hypoparathyroidism (FIH). We found that in none of the 23 affected individuals was ...


    pub_type: 杂志文章


    authors: Ahn TG,Antonarakis SE,Kronenberg HM,Igarashi T,Levine MA

    更新日期:1986-03-01 00:00:00

  • Clinical significance of myositis-specific autoantibody profiles in Japanese patients with polymyositis/dermatomyositis.

    abstract::Myositis-specific autoantibodies, such as anti-melanoma differentiation associated gene 5 (MDA5) and anti-anti-amino acyl-tRNA synthetases (ARS) antibodies, are associated with interstitial lung diseases (ILD), which determine the prognosis of polymyositis/dermatomyositis (PM/DM) patients. However, there is a paucity ...


    pub_type: 杂志文章


    authors: Temmoku J,Sato S,Fujita Y,Asano T,Suzuki E,Kanno T,Furuya MY,Matsuoka N,Kobayashi H,Watanabe H,Koga T,Shimizu T,Kawakami A,Migita K

    更新日期:2019-05-01 00:00:00

  • Value of quantitative and qualitative analyses of circulating cell-free DNA as diagnostic tools for hepatocellular carcinoma: a meta-analysis.

    abstract::Qualitative and quantitative analyses of circulating cell-free DNA (cfDNA) are potential methods for the detection of hepatocellular carcinoma (HCC). Many studies have evaluated these approaches, but the results have been variable. This meta-analysis is the first to synthesize these published results and evaluate the ...


    pub_type: 杂志文章,meta分析


    authors: Liao W,Mao Y,Ge P,Yang H,Xu H,Lu X,Sang X,Zhong S

    更新日期:2015-04-01 00:00:00

  • Thoracolumbar traumatic nucleus pulposus sequestration combined with a slight flexion distraction fracture: A rare case report and literature review.

    abstract:RATIONALE:Traumatic nucleus pulposus sequestration (TNPS) usually occurs concurrently with severe destruction of bone. TNPS combined with a slight thoracolumbar flexion- distraction fracture, triggering a disastrous nerve injury, has rarely been reported. Due to the atypical radiologic manifestations, such a patient ca...


    pub_type: 杂志文章


    authors: Yin R,Chang P,Zhu Q,Cheng F,Zhao B,Gu R,Zhang BY

    更新日期:2018-06-01 00:00:00

  • A case report of targeted therapy with apatinib in a patient with recurrent high grade glioma.

    abstract:RATIONALE:Despite the approval of antiangiogenic therapy for high grade glioma (HGG) patients, survival benefits are still limited. New treatment plans have always been developed to improve the survival. PATIENT CONCERNS:A 26-year-old woman was admitted to our hospital for distending pain of head and eye. DIAGNOSES:R...


    pub_type: 杂志文章


    authors: Ding X,Sun J,Fan T,Li B

    更新日期:2018-06-01 00:00:00

  • Effect of auriculotherapy on chronic low back pain: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Chronic low back pain (CLBP) is a clinically common and recurrent disease. However, many trials have shown that auriculotherapy (AT) can effectively treat CLBP. There are currently no systematic reviews of this therapy. The plan aims to evaluate the effectiveness and safety of this treatment in patients with...


    pub_type: 杂志文章


    authors: Zhang G,Zhang L,Deng Y,Shen Y,Wang X,Yu Y

    更新日期:2020-04-01 00:00:00

  • CD4/CD8 dual-positive mycosis fungoides: A case report and literature review.

    abstract:RATIONALE:Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. It appears as patches, plaques, and tumors depending on the stage of the disease, which presents a chronic progressive course. Compared to CD4/CD8 MF, CD4/CD8 dual-positive MF is an uncommon immune phenotype. PATIENT CONCERNS:A 36-year-old ...


    pub_type: 杂志文章,评审


    authors: Ding X,Chen J,Kuai L,Xing M,Ru Y,Luo Y,Luo Y,Zhou M,Li B,Li X

    更新日期:2020-10-16 00:00:00

  • Primary pulmonary hepatoid adenocarcinoma: A case report and review of the literature.

    abstract:RATIONALE:Hepatoid adenocarcinoma of lung (HAL) is a rare malignant tumor, which can be defined as a primary alpha-fetoprotein (AFP)-producing lung carcinoma. The majority of hepatoid adenocarcinoma (HAC) expressed AFP in tumor cells, but AFP expression is not required for its diagnosis according to the modified diagno...


    pub_type: 杂志文章,评审


    authors: Yang K,Jiang H,Li Q

    更新日期:2019-04-01 00:00:00

  • Pemetrexed-carboplatin with intercalated icotinib in the treatment of patient with advanced EGFR wild-type lung adenocarcinoma: A case report.

    abstract:RATIONALE:Tyrosine kinase inhibitors (TKIs) are known to have greater efficacy in epidermal growth factor receptor (EGFR) mutation nonsmall cell lung cancer (NSCLC). However, about 10% of EGFR wild-type (wt) patients respond to TKIs. PATIENT CONCERNS:Several strategies to increase the efficacy of TKIs in wt NSCLC are ...


    pub_type: 杂志文章


    authors: Xu T,Wu H,Jin S,Min H,Zhang Z,Shu Y,Wen W,Guo R

    更新日期:2017-08-01 00:00:00