Hemolymphangioma involving bones and bladder detected on 68Ga-NEB PET/CT: A rare case report.

Abstract:

RATIONALE:Hemolymphangioma is a rare developmental defect of combined vasal and lymphatic vasculature. It is very rare that hemolymphangioma affects the bones and bladder simultaneously, and this condition has never been reported in PubMed. PATIENT CONCERNS:A 12-year-old male has a history of hospitalization for recurrent episodes of chyluria of 8 years duration and progressively worsening gross hematuria with right hip pain for 6 months. DIAGNOSIS:Chylous test of urine fluid was positive. There was no organic disease in the kidneys. Ga-NOTA-Evans Blue (NEB) positron emission tomography/computed tomography (PET/CT) images demonstrated clearly several round and strip-shaped low-density shadows with mildly increased radioactive uptake in both bladder wall and pelvis, including sacral, pubic, and ischial bones. Histopathological analysis of biopsy on pubic and ischial bones confirmed the diagnosis of hemolymphangioma. INTERVENTIONS:The patient received treatment with traditional Chinese medicine. OUTCOMES:At the 6-month follow-up visit, the patient's symptoms of chyluria, hematuria, and pain were all mitigated. LESSONS:Hemolymphangioma is a rare benign disease. Ga-NEB PET/CT is a specific method for the lymphatic system, and it might provide more accurate and comprehensive information about the disorder of the lymphatic system compared with CT and magnetic resonance imaging. When patients suffer from suspected lesions of the lymphatic system, Ga-NEB PET/CT might be recommended.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Hou G,Jiang Y,Jian S,Niu Y,Cheng W

doi

10.1097/MD.0000000000015213

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

e15213

issue

15

eissn

0025-7974

issn

1536-5964

pii

00005792-201904120-00081

journal_volume

98

pub_type

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