Differential proteomic analysis of serum exosomes reveals alterations in progression of Parkinson disease.

abstract：BACKGROUND:Postoperative pain is caused by surgical trauma and poses a significant challenge for health care providers. Opioid analgesics are commonly used to control postoperative pain. However, these drugs are associated with a number of negative side effects. This review will assess the clinical evidence for and aga...

journal_title：Medicine

authors： Park KM,Kim JH

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) is a common high-burden and highly disabling lung disease. The quality of life and exercise endurance of patients with COPD is often low because of atrophy of the respiratory and skeletal muscles. Although recommended by the global initiative for chronic obstruc...

journal_title：Medicine

authors： Yu W,Su P,Wang J,Zhou P,Chen K,Liu L,Xia Q,Chen Y

更新日期：2020-06-05 00:00:00

abstract：:Bazex syndrome, a rare paraneoplastic syndrome characterized by psoriasiform eruptions, palmoplantar keratosis, and symmetric onychodystrophy, is most prevalent with squamous cell carcinomas of the upper aerodigestive tract.Here, we reported an uncommon case of Bazex syndrome about an 83-year-old man with pulmonary ad...

journal_title：Medicine

authors： Zhao J,Zhang X,Chen Z,Wu JH

更新日期：2016-01-01 00:00:00

abstract：:In the absence of liver biopsy and transient elastography (TE), aspartate aminotransferase to platelet ratio (APRI), fibrosis-4 score (FIB-4), and gammaglutamyl transpeptidase to platelet ratio (GPR) are simple and inexpensive methods for the detection of liver fibrosis. AIMS:We compared the performance of APRI, FIB-...

journal_title：Medicine

authors： Yue W,Li Y,Geng J,Wang P,Zhang L

更新日期：2019-12-01 00:00:00

abstract：:Enterovirus (EV) infection is common among children and adolescents. Few studies have investigated the relationship of depression after EV infection. This study explores an association between EV infection and subsequent depression in children and adolescents and assesses the risk of depression after EV infection with...

journal_title：Medicine

authors： Liao YT,Hsieh MH,Yang YH,Wang YC,Tsai CS,Chen VC,Gossop M

更新日期：2017-02-01 00:00:00

abstract：:Pneumonic-type adenocarcinoma (P-ADC) is a subtype of lung adenocarcinoma with high mortality, which often requires lobectomy surgery. Nonsurgically treated P-ADC patients usually have more advanced or complex conditions, which remain poorly understood and pose a major challenge in clinical management. We aimed to des...

journal_title：Medicine

authors： Wei J,Tang D,Nie Y,Chen J,Peng L

更新日期：2019-05-01 00:00:00

abstract：:There is an increased enthusiasm in treating osteolytic metastatic acetabulum via injecting polymethyl-methacrylate (PMMA) as a bone filler to provide pain relief and potential structural support. The aim of this respective study is to determine the function and quality of life improvement after cement acetabuloplasty...

journal_title：Medicine

authors： Yan T,Zhao Z,Tang X,Guo W,Yang R,Tang S,Dong S

更新日期：2019-09-01 00:00:00

abstract：RATIONALE:Osteopetrosis is a rare disease that predominantly occurs in descendants of inbreeding families. In the case of fractures happen in patients with osteopetrosis, the choice between operative or conservative treatment is still controversial. Open reduction and internal fixation (ORIF) is a conventional treatmen...

journal_title：Medicine

authors： Huang J,Pan J,Xu M,Xu S

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The recent controversy about using mammography to screen for breast cancer based on randomized controlled trials over 3 decades in Western countries has not only eclipsed the paradigm of evidence-based medicine, but also puts health decision-makers in countries where breast cancer screening is still being co...

journal_title：Medicine

authors： Chen TH,Yen AM,Fann JC,Gordon P,Chen SL,Chiu SY,Hsu CY,Chang KJ,Lee WC,Yeoh KG,Saito H,Promthet S,Hamashima C,Maidin A,Robinson F,Zhao LZ

更新日期：2017-01-01 00:00:00

abstract：:Nonadherence to prescribed medications poses a significant public health problem. Prescription data in electronic medical records (EMRs) linked with pharmacy claims data provides an opportunity to examine the prescription fill rates and factors associated with it.Using a claims-EMR linked data, patients who had a pres...

journal_title：Medicine

authors： Park Y,Yang H,Das AK,Yuen-Reed G

更新日期：2018-11-01 00:00:00

abstract：:Immune cells contribute to determining the prognosis of gastric cancer. However, their exact role is less clear. We determined the prognostic significance of different immune cells in intratumoral tissue (T), stromal tissue (S), and adjacent normal tissue (N) of 166 gastric cancer cases and their interactions, includi...

journal_title：Medicine

authors： Liu K,Yang K,Wu B,Chen H,Chen X,Chen X,Jiang L,Ye F,He D,Lu Z,Xue L,Zhang W,Li Q,Zhou Z,Mo X,Hu J

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:This meta-analysis aimed to systematically evaluate the effects of probiotics on blood lipid and blood pressure among patients with type 2 diabetes mellitus (T2DM) based on the randomized controlled studies. METHODS:PubMed, Cochrane, Embase, Wanfang, China National Knowledge Infrastructure, and VIP database...

journal_title：Medicine

authors： He J,Zhang F,Han Y

更新日期：2017-12-01 00:00:00

abstract：:Acute motor axonal neuropathy (AMAN) is a variant of Guillain-Barre syndrome. It has been reported to have no sensory symptoms and is diagnosed by typical electrophysiological findings of low-amplitude or unobtainable compound muscle action potentials with normal sensory nerve action potentials. However, the authors e...

journal_title：Medicine

authors： Lee KS,Han SH

更新日期：2015-01-01 00:00:00

abstract：:Some patients with chronic obstructive pulmonary disease (COPD) have eosinophilic inflammation which may be evaluated via the measurement of fractional exhaled nitric oxide (FeNO) like asthma. The aim of this prospective study was to assess whether FeNO levels can be used to identify patients with COPD with eosinophil...

journal_title：Medicine

authors： Wu YK,Su WL,Huang CY,Yang MC,Chen SY,Lan CC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Chronic pelvic inflammatory disease (CPID) is one of common diseases of department of gynaecology, point to female inside genital and circumferential organization to suffer from infection of all sorts of pathogenic bacteria and cause chronic inflammation sex disease, also cause one of main factors of inferti...

journal_title：Medicine

authors： Wang C,Chen J,Xiao Y,Shen Q

更新日期：2020-12-18 00:00:00

abstract：:The best method to ligate the arteries during laparoscopic cholecystectomy or appendectomy remains controversy. The aim of this study is to introduce a new approach during laparoscopic combined cholecystectomy and appendectomy using a monopolar electrocautery to seal the cystic and appendix arteries. We retrospectivel...

journal_title：Medicine

authors： Liu GB,Mao YY,Yang CP,Cao JL

更新日期：2018-03-01 00:00:00

abstract：:This study aimed to evaluate the association between fracture history and sequential risk of suicidal behavior.A total of 82,804 patients with fractures and 82,804 control subjects without fractures were matched. The influence of fractures on the risk of suicidal behavior-related hospital visit was analyzed using a Co...

journal_title：Medicine

authors： Tsai CH,Cheng WJ,Muo CH,Lin TL

更新日期：2019-01-01 00:00:00

abstract：:We aimed to detect novel genes associated with G protein-coupled receptors (GPCRs) in aldosterone-producing adenoma (APA) and elucidate the mechanisms underlying aldosterone production.Microarray analysis targeting GPCR-associated genes was conducted using APA without known mutations (APA-WT) samples (n = 3) and APA w...

journal_title：Medicine

authors： Kishimoto R,Oki K,Yoneda M,Gomez-Sanchez CE,Ohno H,Kobuke K,Itcho K,Kohno N

更新日期：2016-05-01 00:00:00

abstract：INTRODUCTION:Pneumonia is one of the most important characteristics of coronavirus disease 2019 (COVID-19) and imaging findings of COVID-19 pneumonia are diverse and change over disease course. However, the detailed clinical course of organizing pneumonia (OP) caused by COVID-19 has not been clarified. PATIENT CONCERN...

journal_title：Medicine

authors： Okamori S,Lee H,Kondo Y,Akiyama Y,Kabata H,Kaneko Y,Ishii M,Hasegawa N,Fukunaga K

更新日期：2020-08-28 00:00:00

abstract：:Taking into consideration the progress in cancer treatment, an increase in the number of adult survivors of childhood cancer is expected. These survivors will have received treatment that predisposes them to late morbidity and increased risk of early mortality. The aim of this single-center retrospective cohort study ...

journal_title：Medicine

authors： Livinalli A,Silva MT,Lopes LC

更新日期：2019-03-01 00:00:00

abstract：:The long-term survival of end-stage renal disease (ESRD) patients with hepatitis C virus (HCV) infection who received interferon treatment has not been extensively evaluated.The HCV cohort was the ESRD patients with de novo HCV infection from 2004 to 2011; they were classified into treated and untreated groups accordi...

journal_title：Medicine

authors： Hsu YH,Hung PH,Muo CH,Tsai WC,Hsu CC,Kao CH

更新日期：2015-11-01 00:00:00

abstract：RATIONALE:Adrenocortical carcinoma is a rare aggressive type of cancer whose prognosis is poor, particularly for metastatic entities. Metastatic adrenocortical carcinoma in the spine is a rare disease with no standard curative managements yet. The objective of this study is to report a very rare case of spinal metastas...

journal_title：Medicine

authors： Liu S,Zhou X,Song A,Huo Z,Wang Y,Liu Y

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Treating blood stasis is effective in treating obesity and metabolic diseases in traditional Korean medicine. The aim of this prospective observational study is to determine the effectiveness of the diagnosis index for metabolic diseases with blood stasis by analyzing clinical data and blood samples. METH...

journal_title：Medicine

authors： Ko MM,Jang S,Jung J

更新日期：2020-07-02 00:00:00

abstract：:The aim of this study was to provide an innovative nomogram to predict the risk of >2 positive nodes in patients fulfilling the Z0011 criteria with 1-2 sentinel lymph nodes (SLNs) only retrieved.From 2007 to 2017, at the Breast Unit of ICS Maugeri Hospital 271 patients with 1-2 macrometastatic SLNs, fulfilling the Z00...

journal_title：Medicine

authors： Corsi F,Sorrentino L,Albasini S,Bossi D,Morasso C,Villani L,Truffi M

更新日期：2020-08-28 00:00:00

abstract：:Health care associated infections (HAIs) are currently among the major challenges to the care of hematopoietic stem cell transplantation (HSCT) patients. The objective of the present study was to evaluate the impact of 2% chlorhexidine (CHG) bathing on the incidence of colonization and infection with vancomycin-resist...

journal_title：Medicine

authors： Mendes ET,Ranzani OT,Marchi AP,Silva MTD,Filho JUA,Alves T,Guimarães T,Levin AS,Costa SF

更新日期：2016-11-01 00:00:00

abstract：:The evaluation of the electrically induced bulbocavernosus reflex (BCR) using electromyography (EMG) is a useful tool for evaluating the integrity of sacral spinal segments 2 to 4, and that of their afferent and efferent connections in the urogenital region. In the current retrospective study, the value of this techni...

journal_title：Medicine

authors： Lee DG,Kwak SG,Chang MC

更新日期：2017-05-01 00:00:00

abstract：RATIONALE:The use of musculoskeletal ultrasound (MU) method in the diagnosis of shoulder pain and injury and guidance of injection and pain blocking has been established. However, the treatment of posthemiplegic shoulder pain (HSP) with MU-guided precise physical therapy has not been reported. PATIENT CONCERNS:Here, w...

journal_title：Medicine

authors： Zhang J,Li Y,Wang H

更新日期：2017-12-01 00:00:00

abstract：:Rapid response teams have been adopted to prevent unexpected in-ward cardiac arrest. However, there is no convincing evidence of optimal operation with rapid response team. Our aim was to address the impact of focused rapid response team on the safety of patients in wards. Comparison of focused with extended rapid res...

journal_title：Medicine

authors： Ko BS,Lim TH,Oh J,Lee Y,Yun I,Yang MS,Ahn C,Kang H

更新日期：2020-03-01 00:00:00

abstract：RATIONALE:Chronic subdural hematoma (CSDH) is one of the most common neurosurgical diseases. However, complicated subdural empyema rarely occurs after trepanation and drainage of chronic subdural hematoma. PATIENT CONCERNS:A male patient (77 years old) was admitted to the hospital on the 2nd day of fever after an unde...

journal_title：Medicine

authors： Xue H,Zhang W,Shi L,Zhang Y,Yu B,Yang H

更新日期：2019-12-01 00:00:00

abstract：:Dysphagia can occur among patients receiving medical care despite having no history of neurologic disease. The current study aimed to investigate factors contributing to airway invasion among non-neurologically ill patients with dysphagia.This retrospective study included 52 non-neurologically ill patients who complai...

journal_title：Medicine

authors： Kim KL,Park GY,Kwon DR,Kwon DY,Kwak SG,Cho HK

更新日期：2020-11-06 00:00:00