Abstract:
INTRODUCTION:Carcinoid tumor is one of the most frequent neuroendocrine tumors, and the majority of which are usually observed in the lungs and gastrointestinal tract. The prevalence of ovarian carcinoids is merely 0.1% in ovarian neoplasms and 1% in carcinoid tumors. We described 2 rare cases in our hospital of primary ovarian carcinoid (POC), causing carcinoid syndrome (CS) of the diarrhea, constipation, and carcinoid heart disease. Besides, we also reviewed related literatures about its origin, variant, clinical manifestation, diagnosis methods, pathological features, treatment strategies and prognosis from 2009 to 2019. PATIENT CONCERNS:Case 1 was a 61-year-old postmenopausal woman and presented with diarrhea, abdominal pain, enlargement, bloating and dizziness. Case 2 was a 49-year-old patient who complained of constipation, abdominal pain, bloating, and headache. DIAGNOSIS:Both patients were diagnosed as primary ovarian carcinoid, insular type. INTERVENTIONS:Total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO), omentectomy, pelvic lymphadenectomy, and appendectomy without chemotherapy were performed in case 1. Cervix resection, right salpingo-oophorectomy, appendectomy, and pelvic lesion resection with chemotherapy was conducted in case 2. OUTCOMES:Both patients achieved satisfactory treatment effects. The follow-up period was 18 and 17 months in case 1 and case 2, respectively. Case 1 encountered carcinoid heart disease and received percutaneous transluminal coronary angioplasty (PTCA) postoperatively. Case 2 suffered multiple metastases postoperatively. However, after effective treatment, both patients were in good condition during follow-up duration. CONCLUSION:POC is an extraordinarily rare disease, and commonly with a satisfactory outcome. TAH+BSO with or without postoperative chemotherapy has been considered as an acceptable treatment strategy for POC patients.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Zhai LR,Zhang XW,Yu T,Jiang ZD,Huang DW,Jia Y,Cui MHdoi
10.1097/MD.0000000000021109subject
Has Abstractpub_date
2020-10-02 00:00:00pages
e21109issue
40eissn
0025-7974issn
1536-5964pii
00005792-202010020-00002journal_volume
99pub_type
杂志文章,评审相关文献
MEDICINE文献大全abstract::The survival of patients with head and neck squamous cell carcinoma (HNSCC) can be affected not only by progression of the original cancer or occurrence of a second cancer but also by noncancer health event (NCHE). In this study, we evaluated the prognostic significance of early NCHEs in HNSCC patients after definitiv...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003403
更新日期:2016-05-01 00:00:00
abstract::The association between tuberculosis (TB) and lung cancer is well known. However, carcinogenesis of TB and its connection with epidermal growth factor receptor (EGFR) mutation remains unclear. This study aimed to determine this connection to see if TB can affect the outcome of patients with lung cancer. This is a retr...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000444
更新日期:2015-01-01 00:00:00
abstract::Melanoma, which is usually induced by ultraviolet light exposure and the following DNA damage, is the most dangerous skin cancer. The purpose of the present study was to screen key molecules involved in melanoma.Microarray data of E-MTAB-1862 were downloaded from the ArrayExpress database, which included 21 primary me...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007497
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION:Injection laryngoplasty is a common procedure for patients with vocal fold dysfunction, but the literature on its benefits has been mainly focused on those related to structural lesions or laryngeal nerve involvement. Stroke patients may be at increased risk of aspiration due to insufficient vocal fold mot...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019220
更新日期:2020-02-01 00:00:00
abstract:INTRODUCTION:Despite the benefits, cardiovascular rehabilitation programs (CRPs) have been related to the appearance of signals and symptoms. Risk stratification protocols are commonly used to identify risks during the physical exercise; however, studies that investigate their efficacy to previse signals and symptoms a...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000015700
更新日期:2019-06-01 00:00:00
abstract:INTRODUCTION:Duodenal obstructions caused by congenital anatomic abnormalities are rare in adults. Several patients in whom the duodenal obstruction was caused by a congenital duodenal diaphragm have been described. The duodenal obstruction in the patient presented herein was caused by a transverse septum, which has no...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007093
更新日期:2017-10-01 00:00:00
abstract:RATIONALE:According to previously published studies, treating pediatric patients with congenital pseudarthrosis of the tibia (CPT) is challenging. More effective methods are needed to treat this patient population. PATIENT CONCERNS:A 7-year-old girl with congenital pseudarthrosis of the distal tibia, previously misdia...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013384
更新日期:2018-12-01 00:00:00
abstract:RATIONALE:Philadelphia chromosome-positive mixed phenotype acute leukemia (Ph+ MPAL) is a rare type of leukemia with poor prognosis. Tyrosine kinase inhibitors (TKIs) in combination with chemotherapy have significantly improved its remission rate. However, relapse remains the major obstacle to achieve long survival. Le...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010294
更新日期:2018-04-01 00:00:00
abstract::This retrospective study evaluated the effect of neuromuscular electrical stimulation (NMES) for the treatment of endometriosis-associated pain (EAP).A total of 154 patients with EAP were included and were divided into 2 groups in this retrospective study. Eighty-three patients were assigned a treatment group, and und...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011266
更新日期:2018-06-01 00:00:00
abstract::After successful introduction of anti-Haemophilus influenzae (Hi) serotype b vaccination program in Poland, invasive non-b or nontypeable H. influenzae infections have been reported more frequently alike in other countries all over the world. In this paper, we report 2 cases of H. influenzae serotype f (Hif) meningiti...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002671
更新日期:2016-02-01 00:00:00
abstract::Chronic inflammation may promote development of coronary heart disease. Studies on the relationship between chronic pancreatitis (CP) and cardiovascular diseases are scant.We conducted a nationwide retrospective cohort study to determine the risk of acute coronary syndrome (ACS) in patients with CP.We randomly selecte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003451
更新日期:2016-05-01 00:00:00
abstract::In the published literature there are controversial data to the biomechanical stability of monocortical comparing to the bicortical fixation of metacarpal fractures. The aim of this study was to compare the biomechanical stability of monocortical and bicortical locking osteosynthesis in quasi-static and dynamic 4-poin...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006926
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:The patient's pattern identification has been used for personalized medicine in traditional Korean medicine (TKM) and aims for patient-specific therapy by Korean medical doctors. The pattern identification in this trial will be diagnosed from body constitution questionnaire (BCQ) with a more objective diagno...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016035
更新日期:2019-06-01 00:00:00
abstract::AIDS-associated Kaposi's sarcoma (AIDS-KS) caused by human herpes virus 8 (HHV-8) is the most severe and resistant form of KS tumor. Our aim was to verify whether there is an association between HHV-8 variability and development of AIDS-KS in Brazil by comparing the HHV-8 variability between individuals without and wi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005291
更新日期:2016-11-01 00:00:00
abstract::Antiretroviral therapy (ART) and drug resistance studies worldwide have focused almost exclusively on human immunodeficiency virus type 1 (HIV-1). As a result, there is limited information on ART and drug resistance in HIV-2 patients. In Ghana, the HIV epidemic is characterized by the domination of HIV-1, with cocircu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014313
更新日期:2019-02-01 00:00:00
abstract::This is a single institution nonexperimental study intended to analyze the therapeutic efficacy of topical diazepam in treating symptoms of chronic anal fissures.Anal fissures are a common cause of anal pain. Conventional treatments include nonsteroidal anti-inflammatory drugs, topical creams, such as nitroglycerin an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006853
更新日期:2017-05-01 00:00:00
abstract::The influence of somatostatin/octreotide treatment on outcomes of neonates with congenital chylothorax remains controversial. We retrospectively reviewed our experience with somatostatin/octreotide therapy in neonates with this very rare disease.Fourteen neonates with congenital chylothorax who were treated with somat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007594
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:The kinesin family (KIF) is reported to be aberrantly expressed and significantly correlated with survival outcomes in patients with various cancers. This meta-analysis was carried out to quantitatively evaluate the prognostic values of partial KIF members in cancer patients. METHODS:Two well-known KIF memb...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000018040
更新日期:2019-11-01 00:00:00
abstract::Treatment of hypertrophic scars arising as a result of thermal burns in children is still a big problem. The results of the treatment are not satisfactory for patients and parents, and new methods of treatment are still investigated.We present the use of one of the most modern carbon dioxide (CO2) lasers (Lumenis Enco...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005168
更新日期:2016-10-01 00:00:00
abstract:OBJECTS:The present study aimed to identify the clinicopathological characteristics of colorectal cancer (CRC) with invasive micropapillary components (IMPCs) and the relationship between different amounts of micropapillary components and lymph node metastasis. METHODS:A cohort of 363 patients with CRC who underwent s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020238
更新日期:2020-05-22 00:00:00
abstract::To demonstrate the mechanisms of the curative effect of Saussurea lappa ethanol extract (SLE) against prostate cancer, we evaluated the effect of SLE on the induction of apoptosis and autophagy and investigated whether SLE-induced autophagy exerts a pro-survival or pro-apoptotic effect in lymph node carcinoma of the p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007606
更新日期:2017-07-01 00:00:00
abstract::We aimed to establish a new formula for estimating renal depth, based on anthropometric variables, and to compare the estimates with actual data from a group of living kidney donors undergoing computed tomography angiography (CTA).Renal depths in 167 living kidney donors were measured by CTA. Regression analysis was u...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005940
更新日期:2017-02-01 00:00:00
abstract:RATIONALE:Adrenocortical carcinoma is a rare aggressive type of cancer whose prognosis is poor, particularly for metastatic entities. Metastatic adrenocortical carcinoma in the spine is a rare disease with no standard curative managements yet. The objective of this study is to report a very rare case of spinal metastas...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000018259
更新日期:2019-12-01 00:00:00
abstract::Peritoneal dialysis (PD) is one type of renal replacement therapy, but potential peritoneal damage and gastrointestinal (GI) tract adverse effects during long-term exposure to bio-incompatible dialysate remain a concern. Although GI disease frequently occurs in dialysis patients, whether the risk of GI diseases differ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001482
更新日期:2015-09-01 00:00:00
abstract:RATIONALE:Priapism is a common urologic emergency, but high-flow penile priapism (HFP) caused by trauma is very rare. Therefore, HFP diagnosis and treatment are still not standardized. PATIENT CONCERNS:A 29-year-old man was admitted to the urology department of our hospital on August 01, 2019, due to "persistent penil...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022618
更新日期:2020-10-09 00:00:00
abstract:BACKGROUND:Hypertension is one of the most common chronic diseases and an increasingly public-health challenge worldwide. Previous meta-analyses evaluated the effects of azilsartan medoxomil compared to placebo or other antihypertensive drugs in patients with hypertension. However, it is still unclear which dose of azi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017050
更新日期:2019-09-01 00:00:00
abstract::The aim of this study was to evaluate the effect of prenatal and postnatal malnutrition on the intellectual functioning of early school-aged children. We followed the offspring of women who had participated in a trial of prenatal supplementation with different combinations of micronutrients and who remained resident i...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004161
更新日期:2016-08-01 00:00:00
abstract::Globalization has attracted much attention to universities over the past decade. The aim of this study was to evaluate the effect of the United States-China international pharmacy education programs (IPEP) in China.Kirkpatrick's model of evaluation was used to evaluate IPEP from reaction and learning levels. In the re...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020945
更新日期:2020-07-02 00:00:00
abstract::End-stage renal disease (ESRD) is the final stage of chronic kidney disease in which the kidney is not sufficient to meet the needs of daily life. It is necessary to understand the role of genes expression involved in ESRD patient responses to nocturnal hemodialysis (NHD) and to improve the immunity responsiveness. Th...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012018
更新日期:2018-09-01 00:00:00
abstract::This study aimed to evaluate the clinical usefulness of postoperative surveillance by ultrasound (PSU) in patients after breast cancer surgery.In this retrospective study, 324 patients with breast cancer after mastectomy were included between January 2006 and December 2008. The final-positive lesions (FPL) were diagno...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009244
更新日期:2017-12-01 00:00:00