Elucidation of the Biosynthetic Pathway of Vitamin B Groups and Potential Secondary Metabolite Gene Clusters Via Genome Analysis of a Marine Bacterium Pseudoruegeria sp. M32A2M.

abstract：:Monoamine oxidase (MAO) is found in most cell types and catalyzes the oxidation of monoamines. Three anithiactins (A-C, modified 2-phenylthiazoles) isolated from Streptomyces sp. were tested for inhibitory activity of two isoforms, MAO-A and MAO-B. Anithiactin A was effective and selective for the inhibition of MAO-A,...

journal_title：Journal of microbiology and biotechnology

authors： Lee HW,Jung WK,Kim HJ,Jeong YS,Nam SJ,Kang H,Kim H

更新日期：2015-09-01 00:00:00

abstract：:Ingredients of soy and fermented soy products have been widely utilized as food supplements for health-enhancing properties. The aim of this study was to evaluate the effects of fermented soymilk (FSM) and soymilk (SM) on free fatty acid-induced lipogenesis in the hepatocellular steatosis model. HepG2 cells were incub...

journal_title：Journal of microbiology and biotechnology

authors： Ahn SB,Wu WH,Lee JH,Jun DW,Kim J,Kim R,Lee TB,Jun JH

更新日期：2018-02-28 00:00:00

abstract：:Extremophilic microorganisms have established a diversity of molecular strategies in order to survive in extreme conditions. Biocatalysts isolated by these organisms are termed extremozymes, and possess extraordinary properties of salt allowance, thermostability, and cold adaptivity. Extremozymes are very resistant to...

journal_title：Journal of microbiology and biotechnology

authors： Dumorné K,Córdova DC,Astorga-Eló M,Renganathan P

更新日期：2017-04-28 00:00:00

abstract：:Alcohol dependence is a global public health problem, yet the mechanisms of alcohol dependence are incompletely understood. The traditional view has been that ethanol alters various neurotransmitters and their receptors in the brain and causes the addiction. However, an increasing amount of experimental evidence sugge...

journal_title：Journal of microbiology and biotechnology

authors： Fan Y,Ya-E Z,Ji-Dong W,Yu-Fan L,Ying Z,Ya-Lun S,Meng-Yu M,Rui-Ling Z

更新日期：2018-11-28 00:00:00

abstract：:An electron paramagnetic resonance (EPR) signal characteristic of the 5,5'-dimethyl-1-pyrroline-N-oxide (DMPO)-OH spin adduct, which is formed from the reaction of DMPO with superoxide radicals generated by xanthine oxidase-mediated reaction, was significantly reduced by the cadaverine or Escherichia coli Mn-containin...

journal_title：Journal of microbiology and biotechnology

authors： Kang IH,Kim JS,Kim EJ,Lee JK

更新日期：2007-01-01 00:00:00

abstract：:Our previous report determined that miR-144 is a key regulator of intestinal epithelial permeability in irritable bowel syndrome with diarrhea (IBS-D) rats. Recent evidence has shown that lactobacilli play an important role in the relief of IBS-D symptoms. However, few studies have addressed the mechanisms by which mi...

journal_title：Journal of microbiology and biotechnology

authors： Hou Q,Huang Y,Wang Y,Liao L,Zhu Z,Zhang W,Liu Y,Li P,Chen X,Liu F

更新日期：2020-10-28 00:00:00

abstract：:Whitening effect, tyrosinase inhibitions, and cytotoxicity of neoagarotetraose were measured after purification from hydrolyzed agar by gel filtration chromatography. In melanoma B16F10 cells, melanin content of neoagarotetraose-treated cells was as same as that treated by kojic acid or arbutin. In addition, tyrosinas...

journal_title：Journal of microbiology and biotechnology

authors： Jang MK,Lee DG,Kim NY,Yu KH,Jang HJ,Lee SW,Jang HJ,Lee YJ,Lee SH

更新日期：2009-10-01 00:00:00

abstract：:Many strains of Bacillus cereus cause gastrointestinal diseases, and the closely related insect pathogen Bacillus thuringiensis has also been involved in outbreaks of diarrhea. The diarrheal diseases are attributed to enterotoxins. Sixteen reference strains of B. cereus and nine commercial and 12 reference strains of ...

journal_title：Journal of microbiology and biotechnology

authors： Kim MJ,Han JK,Park JS,Lee JS,Lee SH,Cho JI,Kim KS

更新日期：2015-06-01 00:00:00

abstract：:The biosynthesis study of antibiotics saframycin (SFM) in Streptomyces lavendulae and safracin (SAC) in Pseudomonas fluorescens demonstrated that 3-hydroxy-5-methyl-Omethyltyrosine (3h5mOmTyr), a nonproteinogenic amino acid, is the precursor of the tetrahydroisoquinoline molecular core. In the biosynthetic gene cluste...

journal_title：Journal of microbiology and biotechnology

authors： Fu CY,Tang MC,Peng C,Li L,He YL,Liu W,Tang GL

更新日期：2009-05-01 00:00:00

abstract：:Trichoderma reesei is the major filamentous fungus used to produce cellulase and there is huge interest in promoting its ability to produce higher titers of cellulase. Among the many factors affecting cellulase production in T. reesei, the mycelial phenotype is important but seldom studied. Herein, a close homolog of ...

journal_title：Journal of microbiology and biotechnology

authors： Gao F,Li M,Liu W,Bai Y,Tu T,Wang Y,Zhang J,Luo H,Yao B,Huang H,Su X

更新日期：2020-02-28 00:00:00

abstract：:This study compared the radioprotective effects of high-molecular-weight poly-gamma-glutamate (γ-PGA, average molecular mass 3,000 kDa) and a reduced form of glutathione (GSH, a known radioprotector) on calf thymus DNA damage. The radiation-induced DNA damage was measured on the basis of the decreased fluorescence int...

journal_title：Journal of microbiology and biotechnology

authors： Oh YJ,Kwak MS,Sung MH

更新日期：2018-04-28 00:00:00

abstract：:A series of thiobarbituric acid derivatives were constructed and evaluated for inhibitory activity on hepatitis C virus NS5B polymerase. In biochemical assays using purified viral polymerase and RNA template, the IC(50) value was improved to 0.41 microM from the original compound's 1.7 microM value. In HCV subgenomic ...

journal_title：Journal of microbiology and biotechnology

authors： Lee JH,Lee S,Park MY,Ha HJ,Myung H

更新日期：2010-03-01 00:00:00

abstract：:Monacolin K and yellow pigment, produced by Monascus sp., have each been proven to be beneficial compounds as antihypercholesterolemic and anti-inflammation agents, respectively. However, citrinin, a human toxic substance, was also synthesized in this fungus. In this research, solidstate fermentation of M. purpureus T...

journal_title：Journal of microbiology and biotechnology

authors： Jirasatid S,Nopharatana M,Kitsubun P,Vichitsoonthonkul T,Tongta A

更新日期：2013-03-01 00:00:00

abstract：:The exopolysaccharide (EPS) produced by Bacillus amyloliquefaciens GSBa-1 was isolated and purified by ethanol precipitation, and DEAE-cellulose and Sepharose CL-6B chromatographies. The molecular mass of the purified EPS was determined to be 54 kDa. Monosaccharide analysis showed that the EPS was composed of predomin...

journal_title：Journal of microbiology and biotechnology

authors： Zhao W,Zhang J,Jiang YY,Zhao X,Hao XN,Li L,Yang ZN

更新日期：2018-08-28 00:00:00

abstract：:Several species of Gram-positive bacteria have cell wall peptidoglycan (syn. murein) in which not all of the sugar moieties are N-acetylated. This has recently been shown to be a secondary effect, caused by the action of a peptidoglycan N-acetylglucosamine deacetylase. We have found that the opportunistic pathogen Lis...

journal_title：Journal of microbiology and biotechnology

authors： Popowska M,Kusio M,Szymanska P,Markiewicz Z

更新日期：2009-09-01 00:00:00

abstract：:Soils amended for long-term with high levels of compost demonstrated greater abundance of bacterial members of the phylum Bacteroidetes whereas a decreasing trend in the relative abundance of phylum Acidobacteria was noted with increasing levels of compost. Metabolic profiles predicted by PICRUSt demonstrated differen...

journal_title：Journal of microbiology and biotechnology

authors： Samaddar S,Han GH,Chauhan P,Chatterjee P,Jeon S,Sa T

更新日期：2019-02-28 00:00:00

abstract：:Response surface methodology (RSM) examining the effects of five-level-three-factors and their mutual interactions was utilized to optimize the fermentation conditions to enhance capsular polysaccharide (CPS) production of Streptococcus pneumoniae type 3. Twenty experiments conducted in an 8-l lab-scale fermentor were...

journal_title：Journal of microbiology and biotechnology

authors： Jin SD,Kim YM,Kang HK,Jung SJ,Kim D

更新日期：2009-11-01 00:00:00

abstract：:Enrofloxacin is a fluoroquinolone antibiotic approved for the treatment of infections in animals. Because of the side effects to consumers of animal products, the maximum residue limits (MRLs) of enrofloxacin in animal tissues for consumption are regulated. In this study, a monoclonal antibody (mAb) against enrofloxac...

journal_title：Journal of microbiology and biotechnology

authors： Chusri M,Wongphanit P,Palaga T,Puthong S,Sooksai S,Komolpis K

更新日期：2013-01-01 00:00:00

abstract：:This study describes a novel strategy to regulate the metabolic flux for lactic acid production in Lactobacillus casei. The ldhL gene encoding L-lactate dehydrogenase (L-LDH) was overexpressed in L. casei, and a two-stage oxygen supply strategy (TOS) that maintained a medium oxygen supply level during the early fermen...

journal_title：Journal of microbiology and biotechnology

authors： Ge XY,Xu Y,Chen X,Zhang LY

更新日期：2015-01-01 00:00:00

abstract：:A highly sensitive and specific TaqMan real-time PCR was used to quantify hepatopancreatic parvovirus (HPV) type III infections in wild broodstocks and hatchery-reared postlarvae (PL) of Fenneropenaeus chinensis. Totals of 159 and 162 wild brooders from three locations were captured, and 140 and 180 PL were obtained f...

journal_title：Journal of microbiology and biotechnology

authors： Jang IK,Suriakala K,Kim JS,Meng XH,Choi TJ

更新日期：2011-11-01 00:00:00

abstract：:Phenol-soluble modulins (PSMs) are responsible for regulating biofilm formation, persister cell formation, pmtR expression, host cell lysis, and anti-bacterial effects. To determine the effect of psm deletion on methicillin-resistant Staphylococcus aureus, we investigated psm deletion mutants including Δpsmα, Δpsmβ, a...

journal_title：Journal of microbiology and biotechnology

authors： Song HS,Bhatia SK,Choi TR,Gurav R,Kim HJ,Lee SM,Park SL,Lee HS,Joo HS,Kim W,Seo SO,Yang YH

更新日期：2021-01-28 00:00:00

abstract：:The aim of this work is to investigate the protective efficacy of emodin, an active, naturally-occurring anthraquinone derivative of several traditional Chinese herbs, against Brucella abortus infection in macrophages. Brucella were incubated with different concentrations of emodin and showed that bacterial survival r...

journal_title：Journal of microbiology and biotechnology

authors： Huy TXN,Reyes AWB,Hop HT,Arayan LT,Son VH,Min W,Lee HJ,Kim S

更新日期：2018-10-28 00:00:00

abstract：:Four series (S, M, R, and W) of Alternaria longipes isolates were obtained based on consecutive induction with Dimethachlon (Dim) and ultraviolet irradiation. These isolates were then characterized according to their tolerance to Dim, sensitivity to osmotic stress, and phenotypic properties. All the induced Dim-resist...

journal_title：Journal of microbiology and biotechnology

authors： Luo Y,Yang J,Zhu M,Yan J,Mo M,Zhqng K

更新日期：2008-01-01 00:00:00

abstract：:The infection of pandemic influenza viruses such as swine flu (H1N1) and avian flu viruses to the host cells is related to the following two factors: First, the surface protein such as HA (hemagglutinin) and NA (neuraminidase) of the influenza virus. Second, the specific structure of the oligosaccharide [sialic acid(a...

journal_title：Journal of microbiology and biotechnology

authors： Yoo ES

更新日期：2011-05-01 00:00:00

abstract：:The application of steroids has steadily increased thanks to their therapeutic effects. However, alternatives are required due their severe side effects; thus, studies on the activities of steroid derivatives are underway. Sugar derivatives of nandrolone, which is used to treat breast cancer, as well as cortisone and ...

journal_title：Journal of microbiology and biotechnology

authors： Yu EJ,Yamaguchi T,Lee JH,Lim AR,Lee JH,Park H,Oh TJ

更新日期：2020-04-28 00:00:00

abstract：:Polyhydroxyalkanoate (PHA) synthase is a key enzyme for PHA production in microorganisms. The class IV PHA synthase is composed of two subunits: PhaC and PhaR. The PhaR subunit, which encodes the phaR gene, is only present in class IV PHA synthases. Therefore, the phaR gene is used as a biomarker for bacteria that con...

journal_title：Journal of microbiology and biotechnology

authors： Wint NY,Han KK,Yamprayoonswat W,Ruangsuj P,Mangmool S,Promptmas C,Yasawong M

更新日期：2019-01-28 00:00:00

abstract：:The abundance, biomass, size distribution, and taxonomic composition of bacterial and protistan (heterotrophic and autotrophic nanoflagellates and ciliates) communities were investigated in six lakes of Masurian Lake District (north-eastern Poland) differing in trophic state. Samples were taken from the trophogenic wa...

journal_title：Journal of microbiology and biotechnology

authors： Ryszard CJ,Tomasz A,Kalinowska K,Skowronska A

更新日期：2009-09-01 00:00:00

abstract：:Hepatitis B core antigen (HBcAg) is an important serological marker used in the diagnosis of hepatitis B virus (HBV) infections. In the current study, a fast and efficient preparative purification protocol for truncated HBcAg from Escherichia coli disruptate was developed. The recombinant HBcAg was first captured by a...

journal_title：Journal of microbiology and biotechnology

authors： Ho CW,Tan WS,Chong FC,Ling TC,Tey BT

更新日期：2009-04-01 00:00:00

abstract：:A cDNA encoding cysteine protease inhibitor (CPI) was isolated from the cDNA library of clamworm Perinereis aibuhitensis Grube. The deduced amino acid sequence analysis showed that the protein had 51%, 48%, and 48% identity with Zgc:153129 from Danio rerio, cystatin B from Theromyzon tessulatum and ChainA, stefin B te...

journal_title：Journal of microbiology and biotechnology

authors： Li S,Guo D,Zhao B,Ye J,Tian J,Ren W,Ju Y,Cui P,Li R

更新日期：2010-08-01 00:00:00

abstract：:Lactobacillus species have been shown to enhance intestinal epithelial barrier function, modulate host immune responses, and suppress the growth of pathogenic bacteria, yeasts, molds, and viruses. Thus, lactobacilli have been used as probiotics for treating various diseases, including intestinal disorders, and as biol...

journal_title：Journal of microbiology and biotechnology

authors： Eom JS,Song J,Choi HS

更新日期：2015-04-01 00:00:00