Abstract：
BACKGROUND:This study compares survival in patients with the rare subtypes of follicular (FTmC) and Hurthle cell (HCmC) microcarcinoma compared to that of papillary thyroid (PTmC) microcarcinoma. METHODS:Patients with FTmC and HCmC were selected from the National Cancer Database 2004-2015 and compared with PTmC. Patient clinicopathological characteristics and overall survival (OS) were analyzed. Multivariable logistic and Cox regression analysis evaluated binary outcomes and predictors of survival. A propensity score matched analysis using age, gender, race, extrathyroidal extension (ETE), nodal status, distant metastasis, radiation, and operation was performed to evaluate the difference in OS with FTmC, HCmC, and PTmC. RESULTS:We identified 858 FTmC, 476 HCmC, and 82,056 PTmC. FTmC was less likely to have macroscopic ETE compared to PTmC (2.6% vs. 3.1% p = 0.03), but more likely to have distant metastasis (2.3% vs. 0.2%, p < 0.01). FTmC and HCmC were less likely to have nodal metastasis (2.7%, 2.5% vs. 10.9%, p < 0.01). Ten-year OS was decreased in patients with FTmC (91.4%, p = 0.04) and HCmC (89.8%, p < 0.01) compared to PTmC (93.5%). On multivariable analysis, histology was not associated with OS. With HCmC, older age (OR 1.13, p < 0.01) and male gender (OR 2.72, p = 0.03) were associated with decreased OS. In propensity matched analysis, there was no difference in 10-year OS with FTmC and PTmC (91.4% vs. 93.7%, p = 0.54), but HCmC had decreased OS compared to PTmC (89.8% vs. 94.3%, p = 0.04). CONCLUSIONS:Patients with FTmC have comparable OS to those with PTmC, but HCmC has decreased OS especially in older and male patients.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Khokar AM,Holoubek SA,Kuchta KM,Winchester DJ,Prinz RA,Moo-Young TAdoi
10.1007/s00268-019-05264-9subject
Has Abstractpub_date
2020-02-01 00:00:00pages
469-478issue
2eissn
0364-2313issn
1432-2323pii
10.1007/s00268-019-05264-9journal_volume
44pub_type
杂志文章abstract：:This article attempts to put into a risk-related perspective modern red blood cell (RBC) transfusion therapy. When making the decision to transfuse, RBCs or blood products, it is important to weigh the risks and benefits of the proposed therapy. It is equally important to evaluate the risk of not transfusing and the m...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900181
更新日期：1996-11-01 00:00:00
abstract：BACKGROUND:Early mortality in ruptured abdominal aneurysm (rAAA) is high, but data on long-term outcome are scarce. The aim of this study was to investigate the long-term outcome in survivors after open surgery for rAAA in well-defined population. METHODS:This is a population-based, observational long-term follow-up (...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05457-7
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Laparoscopic cholecystectomy is first-line treatment for uncomplicated gallstone disease in high-income countries due to benefits such as shorter hospital stays, reduced morbidity, more rapid return to work, and lower mortality as well-being considered cost-effective. However, there persists a lack of uptake...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3851-0
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:The fields of surgery and trauma care have largely been neglected in the global health discussion. As a result the idea that surgery is not safe or cost effective in resource-limited settings has gone unchallenged. The SIGN Online Surgical Database (SOSD) is now one of the largest databases on trauma surgery...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1817-4
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:The prognosis of intrahepatic cholangiocarcinoma (ICC) remains poor despite improvements in treatment and post-operative clinical management. We review our experiences and evaluate our current surgical approaches by comparing patients from two consecutive treatment periods. METHODS:One hundred forty-four pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3583-1
更新日期：2016-09-01 00:00:00
abstract：:The prognosis of patients who undergo resection for pancreatic ductal adenocarcinoma with curative intention is generally poor unless they have early-stage disease. Based on our 25-year experience, the results of 194 patients after a standardized Kausch-Whipple resection for adenocarcinoma of the pancreatic head were ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6659-z
更新日期：2003-03-01 00:00:00
abstract：:Chondrosarcomas of the head and neck are uncommon. Over a 35-year period (1950-1985) at our institution, 557 patients had an established diagnosis of chondrosarcoma. In 28 (5%) of these patients, the tumor was located in the head and neck region. A retrospective analysis was performed in an attempt to accurately defin...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067021
更新日期：1992-09-01 00:00:00
abstract：:Patients with short bowel syndrome (SBS) receiving total parenteral nutrition (TPN) have a high incidence of catheter-related sepsis, one of its major complications. The aim of this study was to correlate the length of remaining small bowel (RSB) with septic episodes related to the central venous catheter in a group o...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680010274
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:We determined the rates of initial lymph node metastasis following curative resection of mass-forming type-intrahepatic cholangiocarcinoma (ICC) in patients with and without hepatitis virus infection. METHODS:We enrolled 87 patients between January 2000 and December 2013 with ICC without preo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3843-0
更新日期：2017-04-01 00:00:00
abstract：:Variceal bleeding remains an important complication in extrahepatic portal vein thrombosis (EPVT). As for portal hypertension due to other etiologies, an elective treatment to decrease the risk of subsequent rebleeding is warranted. The results of the Sugiura-Futagawa procedure (SP) in 38 patients with variceal bleedi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00294409
更新日期：1994-03-01 00:00:00
abstract：:Intraabdominal bleeding, the most life-threatening complication following pancreaticoduodenectomy (PD), most often is associated with failure of a pancreaticojejunostomy anastomosis or with intraabdominal infection. We investigated whether placement of an omental flap around the splanchnic vessels in PD could reduce t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7900-3
更新日期：2005-09-01 00:00:00
abstract：:With the recent regulations limiting resident work hours, it has become more important to understand how residents spend their time. The volume and content of the pages they receive provide a valuable source of information that give insight into their workload and help identify inefficiencies in hospital communication...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0740-9
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Surgery for Graves' disease (GD) is usually performed after adequate control with medical treatment. Occasionally, rapid pre-operative optimization is required. The primary objective was to compare the outcomes of patients undergoing elective surgery for well-controlled GD with those undergoing rapid pre-ope...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05125-5
更新日期：2019-12-01 00:00:00
abstract：:Of the 2790 patients with gastric carcinoma who underwent surgery between January 1978 and December 1993, there were 224 who underwent a D2 resection for cancer of the proximal third of the stomach. Survival in these patients was retrospectively analyzed with special reference to the survival benefit of pancreaticospl...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900283
更新日期：1997-07-01 00:00:00
abstract：:Central pancreatectomy is an uncommonly performed procedure that may be particularly useful for the removal of benign and low malignant potential lesions in the neck and body of the pancreas. This procedure may have fewer major complications and better preserve endocrine and exocrine function than the more commonly pe...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6848-4
更新日期：2003-05-01 00:00:00
abstract：:Neoadjuvant therapy for locally advanced breast cancer improves disease control, but the complications of treatment are not well established. The aim of this study was to assess the operative morbidity in 20 consecutive patients with locally advanced, noninflammatory breast cancer treated with preoperative chemotherap...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658934
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:There have been no reports on the impact of preoperative biliary MRSA infection on the outcome of major hepatectomy. The aim of this study was to review the surgical outcome of patients who underwent hepatobiliary resection after biliary drainage and to evaluate the impact of preoperative biliary MRSA infect...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-0990-1
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:There are many reports about limited surgery for intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. However, there is no consensus on limited surgery for IPMNs. The primary objective of this study was to define the clinical indications for limited surgery for IPMNs. METHODS:The data of 98 pat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3824-3
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:The psychiatric population has been reported to be accompanied with a higher morbidity and mortality in several situations. However, little is known about the effect of co-morbid psychiatric disorders on surgical risk during major digestive surgery for malignancies. Our purpose in the present study, therefor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9267-0
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:The role of neutrophil-to-lymphocyte ratio (NLR) and preoperative prediction model in gastric cancer is controversial, while postoperative prognostic models are available. This study investigated NLR as a preoperative prognostic indicator in gastric cancer. METHODS:We reviewed patients with primary gastric ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4510-4
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Complications following esophagectomy are a significant source of morbidity. The aim of this study was to investigate the utility of the neutrophil:lymphocyte ratio (NLR) in the early identification of complications following esophagectomy, as compared to other routinely available parameters. METHODS:We per...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3427-z
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:The aim of the present study was to evaluate the effects of surgically induced weight loss on the metabolic profile and adipocytokine levels in premenopausal morbidly obese females. METHODS:Twenty premenopausal morbidly obese (MO) women with a median age of 34 years (range: 24-48 years) and a median body ma...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1165-9
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Owing to an aging society, both the number of operations for patients aged >85 years and the average age of patients admitted to the intensive care unit (ICU) are rapidly increasing. However, mortality is not an appropriate outcome measurement in patients aged >85 years; a more important outcome is home retu...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3830-5
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Medullary thyroid cancer (MTC) is characterized by early regional lymph node metastasis, the presence of which represents a critical obstacle to cure. At present no molecular markers have been successfully integrated into the clinical care of sporadic MTC. The present study was designed to evaluate TP53INP1 ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0395-6
更新日期：2010-04-01 00:00:00
abstract：INTRODUCTION:Hypoxic stress is a feature of rapidly growing thyroid tumours. Cancer progression is thought to be driven by a small population of tumour cells possessing stem cell properties. Hypoxia-inducible factors (HIFs) are important mediators of hypoxia. Both HIF-1alpha and HIF-2alpha have been reported to be expr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4331-x
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Postoperative ileus is a common problem with significant clinical and economic consequences. We hypothesized that Gastrografin may have therapeutic utility by accelerating the recovery of postoperative ileus after colorectal surgery. The aim of this trial was to study the impact of oral Gastrografin administ...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-015-3260-9
更新日期：2016-01-01 00:00:00
abstract：:The epidermal growth factor receptor family consists of four closely related transmembrane receptors: epidermal growth factor receptor (EGF-R), c-erbB-2, c-erbB-3, and c-erbB-4. Overexpression of each receptor may lead to cell transformation and contributes to tumor progression in various malignancies. Although these ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900616
更新日期：1999-10-01 00:00:00
abstract：BACKGROUND:Transient postthyroidectomy hypocalcemia occurs in up to 30% of patients. We evaluated the effect of vitamin D deficiency on postthyroidectomy hypocalcemia. METHODS:Data were collected prospectively between January 2006 and March 2009. A total of 166 consecutive total thyroidectomies were analyzed regarding...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0872-y
更新日期：2011-02-01 00:00:00
abstract：:Eighty patients undergoing cholecystectomy were either assigned deliberately (n = 30) or randomized (n = 50) to drainage (n = 38) or nondrainage (n = 42). Subhepatic collections were seen on ultrasonography (US) after 48 to 72 hours in 12 of 35 patients with drainage and 24 of 42 patients without drainage (p < 0.05). ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01655718
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Surgeon performed ultrasound (US) is being increasingly embraced by breast surgeons worldwide as an integral part of patient assessment. The extent of its application within Australia and New Zealand is not well documented. The present study aimed to evaluate its current usage patterns and to determine suita...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2076-8
更新日期：2013-09-01 00:00:00
