DNA Repair Protein Rad51 Induces Tumor Growth and Metastasis in Esophageal Squamous Cell Carcinoma via a p38/Akt-Dependent Pathway.

abstract：BACKGROUND:The overall incidence of gastric cancer (GC) is higher in males than females. Specifically, signet ring cell carcinoma (SRC) is more frequently observed in younger female patients. However, limited information focused on sex-specific differences in GC has been reported. The aim of our study was to analyze cl...

journal_title：Annals of surgical oncology

authors： Kim HW,Kim JH,Lim BJ,Kim H,Kim H,Park JJ,Youn YH,Park H,Noh SH,Kim JW,Choi SH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Vitamin B12 deficiency is a common long-term sequelae after total gastrectomy. Intramuscular injection of vitamin B12 is the only known treatment. We investigated the efficacy and safety of oral vitamin B12 replacement for gastric cancer patients with vitamin B12 deficiency after total gastrectomy. METHODS:...

journal_title：Annals of surgical oncology

authors： Kim HI,Hyung WJ,Song KJ,Choi SH,Kim CB,Noh SH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Long-term transcutaneous tunneled central venous catheters are frequently placed in cancer patients, accounting for significant costs and morbidity. Factors influencing outcome, though, are poorly studied. METHODS:Between June 1991 and June 1993, 923 central venous tunneled catheters were placed in 791 pati...

journal_title：Annals of surgical oncology

authors： Schwarz RE,Coit DG,Groeger JS

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Cytotoxic T lymphocyte-associated antigen (CTLA)-4 can inhibit T-cell responses and is involved in tolerance against self antigens. We previously reported autoimmune manifestations and objective cancer regressions in patients with metastatic melanoma treated with CTLA-4 blockade. The possibility of activatin...

journal_title：Annals of surgical oncology

authors： Maker AV,Phan GQ,Attia P,Yang JC,Sherry RM,Topalian SL,Kammula US,Royal RE,Haworth LR,Levy C,Kleiner D,Mavroukakis SA,Yellin M,Rosenberg SA

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Microsatellites are short repetitive nucleotide sequences that, through mutation, can undergo either expansion or contraction. This novel mutational mechanism known as microsatellite instability may play a role in carcinogenesis. We investigated the incidence of microsatellite instability in a series of prim...

journal_title：Annals of surgical oncology

authors： Rush EB,Calvano JE,van Zee KJ,Zelenetz AD,Borgen PI

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Intraoperative imprint cytology (IC) is one of several accurate, proven methods to detect tumor cells in sentinel lymph nodes (SLN) from patients with operable breast cancer. In patients treated with neoadjuvant chemotherapy (NAC), studies have demonstrated the feasibility and accuracy of SLN biopsy procedur...

journal_title：Annals of surgical oncology

authors： Gimbergues P,Dauplat MM,Durando X,Abrial C,Le Bouedec G,Mouret-Reynier MA,Cachin F,Kwiatkowski F,Tchirkov A,Dauplat J,Penault-Llorca F

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:To analyze the relationship of objective and subjective evaluation tools of breast aesthetics, we compare the results of the BCCT.core (breast cancer conservative treatment.cosmetic results) software, a semiautomated objective symmetry evaluation tool, with those of the Aesthetic Status of the BCTOS (Breast ...

journal_title：Annals of surgical oncology

authors： Heil J,Dahlkamp J,Golatta M,Rom J,Domschke C,Rauch G,Cardoso MJ,Sohn C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The efficacy, toxicity, and patterns of failure of esophageal squamous cell carcinoma (ESCC) treated with selective lymph node (SLN) conventional fraction radiotherapy (CFRT) and S-1 plus cisplatin (CDDP) were evaluated. PATIENTS AND METHODS:67 Patients with clinical stage II-IVa ESCC were enrolled. The tot...

journal_title：Annals of surgical oncology

authors： Wang X,Liu X,Li D,Wang X,Huang W,Li B

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The routine use of external beam radiotherapy (EBRT) is not recommended for parathyroid carcinoma (PC). However, case series have demonstrated a potential benefit in preventing local recurrence with EBRT. We aimed to characterize the patient population treated with EBRT and identify any impact of EBRT on ove...

journal_title：Annals of surgical oncology

authors： Limberg J,Stefanova D,Ullmann TM,Thiesmeyer JW,Bains S,Beninato T,Zarnegar R,Fahey TJ 3rd,Finnerty BM

更新日期：2021-01-01 00:00:00

abstract：:Integrins play an important role in various lymphocyte functions. In this study, we isolated lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) from normal and malignant tissues in patients with colorectal cancer, and examined the expression of beta1 and beta2 integrins on these lymphocytes quan...

journal_title：Annals of surgical oncology

authors： Kitayama J,Tuno N,Nakayama H,Shibata Y,Muto T,Nagawa H

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer accounts for approximately 3% of cancer deaths in Europe. Locally advanced pancreatic cancer (LAPC) involves vascular structures, and resectability is low, with a median survival time of 6 to 11 months. We conducted a prospective, nonrandomized study of patients with LAPC to assess the effe...

journal_title：Annals of surgical oncology

authors： Polistina F,Costantin G,Casamassima F,Francescon P,Guglielmi R,Panizzoni G,Febbraro A,Ambrosino G

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Despite a growing body of literature on oncologic and reconstructive outcomes after total skin-sparing mastectomy (TSSM), some questions related to this approach remain unanswered, including strategies for managing tumor involvement of the nipple while maintaining the aesthetic benefits of TSSM. METHODS:A p...

journal_title：Annals of surgical oncology

authors： Amara D,Peled AW,Wang F,Ewing CA,Alvarado M,Esserman LJ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:There is no consensus as to the impact of lymph node micrometastasis on survival of patients with gastric cancer. The aim of this study was to clarify the prognostic significance of lymph node micrometastasis in patients with histologically node-negative gastric cancer. METHODS:Lymph nodes (n = 2039) from 6...

journal_title：Annals of surgical oncology

authors： Yasuda K,Adachi Y,Shiraishi N,Inomata M,Takeuchi H,Kitano S

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:This study was designed to determine the role of laparoscopic adrenalectomy (LA) in the surgical management of adrenocortical carcinoma (ACC). METHODS:A systematic literature review was performed on January 2, 2015 using PubMed. Article selection proceeded according to PRISMA criteria. Studies comparing open a...

journal_title：Annals of surgical oncology

authors： Autorino R,Bove P,De Sio M,Miano R,Micali S,Cindolo L,Greco F,Nicholas J,Fiori C,Bianchi G,Kim FJ,Porpiglia F

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Randomized clinical trials (RCTs) can provide a high level of evidence for medical decision making, but it is unclear if the results apply to patients treated outside such trials. OBJECTIVE:The aim of this study was to retrospectively compare outcomes of patients with esophageal cancer treated within and ou...

journal_title：Annals of surgical oncology

authors： Toxopeus E,van der Schaaf M,van Lanschot J,Lagergren J,Lagergren P,van der Gaast A,Wijnhoven B

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Overall survival (OS) has traditionally been the primary end point in studies evaluating the clinical benefit of first-line chemotherapy in metastatic, locally advanced, or unresectable pancreatic cancer (MLAUPC). Given the prolonged follow-up assessment required to obtain OS and its potential to be confound...

journal_title：Annals of surgical oncology

authors： Makris EA,MacBarb R,Harvey DJ,Poultsides GA

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The aim of this clinical study was to evaluate quality of life (QoL) in early-stage breast cancer patients and to investigate the effects of a comprehensive rehabilitation program comparing women undergoing sentinel node biopsy (SNB) versus complete axillary lymph node dissection (ALND). QoL was assessed wit...

journal_title：Annals of surgical oncology

authors： Pinto e Silva MP,Sarian LO,Morais SS,Pace do Amaral MT,Freire de Oliveira MM,Derchain S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Metaplastic breast cancer (MBC) is characterized by various combinations of adenocarcinoma, mesenchymal, and other epithelial components. It was officially recognized as a distinct pathologic diagnosis in 2000. With few published reports, we hypothesized that MBC may have markedly different characteristics a...

journal_title：Annals of surgical oncology

authors： Pezzi CM,Patel-Parekh L,Cole K,Franko J,Klimberg VS,Bland K

更新日期：2007-01-01 00:00:00

abstract：:Preoperative needle diagnosis (PND) is being considered as a quality measure in breast cancer surgery. This criterion has not been thoroughly evaluated in the literature. The purpose of this study is to assess ease of access to these data and rate of compliance in a tertiary care center. We retrospectively reviewed al...

journal_title：Annals of surgical oncology

authors： Pocock B,Taback B,Klein L,Joseph KA,El-Tamer M

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Surgical resection is the most important therapeutic intervention for eligible patients with pancreatic cancer; however, a majority of patients never receive surgery for a variety of reasons, including patient refusal. Utilizing the National Cancer Database, we investigated the associated sociodemographic an...

journal_title：Annals of surgical oncology

authors： Coffman A,Torgeson A,Lloyd S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The Oncotype DX® assay has been validated in predicting response to adjuvant chemotherapy in breast cancer. Its role in neoadjuvant chemotherapy (NCT) has not been established. METHODS:The National Cancer Database was used to identify all patients with T1-T3, ER-positive, HER2-negative primary invasive brea...

journal_title：Annals of surgical oncology

authors： Pease AM,Riba LA,Gruner RA,Tung NM,James TA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:This anatomic study details the lymphatic drainage of the upper extremity (UE) and breast, as well as its course in the axilla and its relation to axillary reverse mapping. Two aspects important for breast cancer surgery were followed: connection between the lymphatics of the UE and breast, and the possible ...

journal_title：Annals of surgical oncology

authors： Pavlista D,Eliska O

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:This study investigated the effects of preoperative chemoradiotherapy (PCRT) and the prognoses of patients with mucinous rectal cancer compared with those with nonmucinous cancer. METHODS:We retrospectively reviewed the medical records of 368 patients who underwent curative resection after PCRT, between 200...

journal_title：Annals of surgical oncology

authors： Shin US,Yu CS,Kim JH,Kim TW,Lim SB,Yoon SN,Yoon YS,Kim CW,Kim JC

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The locoregional recurrence (LRR) rate after mastectomy is reported to be similar with immediate reconstruction. We aimed to identify characteristics of LRR after transverse rectus abdominis myocutaneous (TRAM) reconstruction. METHODS:We retrospectively reviewed patients undergoing immediate TRAM reconstruc...

journal_title：Annals of surgical oncology

authors： Patterson SG,Teller P,Iyengar R,Carlson GW,Gabram-Mendola SG,Losken A,Styblo T,Torres M,Wood WC,Perez SD,Mosunjac M,Rizzo M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Calciphylaxis is a rare condition associated with chronic renal failure and entails a very poor prognosis. Pathogenesis is poorly understood but involves abnormalities in calcium and phosphorus metabolism that lead to vascular and extravascular calcification. Patients present with painful ulcerating plaques ...

journal_title：Annals of surgical oncology

authors： Duffy A,Schurr M,Warner T,Chen H

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) has become standard of care as a staging procedure in patients with invasive breast cancer. A positive SLNB allows completion axillary lymph node dissection (cALND) to be performed. The axillary recurrence rate (ARR) after cALND in patients with positive SLNB is low. Recentl...

journal_title：Annals of surgical oncology

authors： Francissen CM,Dings PJ,van Dalen T,Strobbe LJ,van Laarhoven HW,de Wilt JH

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). Although the absolute number of nodes involved with cancer is important for prognosis, the role of the total number of excised nodes ...

journal_title：Annals of surgical oncology

authors： Hatoum HA,Jamali FR,El-Saghir NS,Musallam KM,Seoud M,Dimassi H,Abbas J,Khalife M,Boulos FI,Tawil AN,Geara FB,Salem Z,Shamseddine AA,Al-Feghali K,Shamseddine AI

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new technology for delivering intraperitoneal chemotherapy. It is generally assumed that with PIPAC, the ratio of peritoneal to systemic drug concentration is superior to liquid hyperthermic intraperitoneal chemotherapy (HIPEC). To date, no direct...

journal_title：Annals of surgical oncology

authors： Giger-Pabst U,Bucur P,Roger S,Falkenstein TA,Tabchouri N,Le Pape A,Lerondel S,Demtröder C,Salamé E,Ouaissi M

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:In one third of patients who die of rectal cancer, a pelvic recurrence after resection represents isolated disease for which re-resection may provide cure. These extensive resections can carry high morbidity. Proper patient selection is desirable but difficult. Hydronephrosis has been documented previously t...

journal_title：Annals of surgical oncology

authors： Henry LR,Sigurdson E,Ross E,Hoffman JP

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Few studies have been undertaken to evaluate the prognostic value of age at diagnosis for determining breast cancer survival in a large population. METHODS:Using the U.S. National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database consisting of 18 population-based cancer registri...

journal_title：Annals of surgical oncology

authors： Liu YR,Jiang YZ,Yu KD,Shao ZM

更新日期：2015-04-01 00:00:00