Abstract:
:High oxygen affinity hemoglobins (Hbs), characterized by a decreased ability to release oxygen to the tissues and a left-shifted oxygen dissociation curve, are a rare cause of secondary erythrocytosis. Here, we report a base substitution in the β-globin gene at codon 89 (AGT>AGG) in a kindred with familial erythrocytosis resulting in Hb Vanderbilt, a high oxygen affinity variant.
journal_name
Hemoglobinjournal_title
Hemoglobinauthors
Shomali W,Brar R,Arekapudi SR,Gotlib JRdoi
10.1080/03630269.2019.1680382subject
Has Abstractpub_date
2019-01-01 00:00:00pages
273-276issue
4-5eissn
0363-0269issn
1532-432Xjournal_volume
43pub_type
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