Abstract:
:Hb Westmead or alpha 2 122(H5)His----Gln beta 2 is one of the most common hemoglobin variants in Guangxi, a province in Southern China. The alpha 2-globin DNA sequence of a carrier for this variant was selectively amplified by the polymerase chain reaction and analyzed with the restriction enzyme Stu I. We found that this mutant globin was encoded at the alpha 2 locus and that the CAC----CAG mutation at codon 122 created a new Stu I restriction site. It is easy to detect this mutation by these methods.
journal_name
Hemoglobinjournal_title
Hemoglobinauthors
Jiang NH,Liang S,Wen XJ,Liang R,Su C,Tang Zdoi
10.3109/03630269109027881subject
Has Abstractpub_date
1991-01-01 00:00:00pages
291-5issue
4eissn
0363-0269issn
1532-432Xjournal_volume
15pub_type
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