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ASJA: A Program for Assembling Splice Junctions Analysis.

Abstract：

:RNA splicing may generate different kinds of splice junctions, such as linear, back-splice and fusion junctions. Only a limited number of programs are available for detection and quantification of splice junctions. Here, we present Assembling Splice Junctions Analysis (ASJA), a software package that identifies and characterizes all splice junctions from high-throughput RNA sequencing (RNA-seq) data. ASJA processes assembled transcripts and chimeric alignments from the STAR aligner and StringTie assembler. ASJA provides the unique position and normalized expression level of each junction. Annotations and integrative analysis of the junctions enable additional filtering. It is also appropriate for the identification of novel junctions. ASJA is available at https://github.com/HuangLab-Fudan/ASJA.

journal_name

Comput Struct Biotechnol J

journal_title

Computational and structural biotechnology journal

authors

Zhao J,Li Q,Li Y,He X,Zheng Q,Huang S

doi

10.1016/j.csbj.2019.08.001

subject

Has Abstract

pub_date

2019-08-07 00:00:00

pages

1143-1150

issn

2001-0370

pii

S2001-0370(19)30066-2

journal_volume

17

pub_type

杂志文章

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