Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes.

Abstract:

:Early diabetic kidney disease (DKD) occurs in adolescents with type 1 diabetes (T1D). Lower serum uromodulin (SUMOD) predicts DKD progression in adults with T1D. In this study, we demonstrate that lower SUMOD is associated with urinary albumin excretion in adolescents with T1D, suggesting a potential relationship between SUMOD and early kidney dysfunction in T1D youth.

authors

Wiromrat P,Bjornstad P,Roncal C,Pyle L,Johnson RJ,Cherney DZ,Lipina T,Bishop F,Maahs DM,Wadwa RP

doi

10.1016/j.jdiacomp.2019.05.023

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

648-650

issue

9

eissn

1056-8727

issn

1873-460X

pii

S1056-8727(19)30197-7

journal_volume

33

pub_type

杂志文章
  • Albuminuria in normals and essential hypertension.

    abstract::The prevalence and determinants of urinary albumin excretion rate (AER) were assessed in lean and overweight normotensive subjects (NT) and patients with essential hypertension (EH). In NT and EH, the presence of overweight was associated with a significant exacerbation of AER. In the normotensive population, AER was ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(94)90032-9

    authors: Mimran A,Ribstein J,DuCailar G,Halimi JM

    更新日期:1994-07-01 00:00:00

  • Mutation H63D in the HFE gene confers risk for the development of type 2 diabetes mellitus but not for chronic complications.

    abstract:PURPOSE:To evaluate the frequency of mutations in the HFE gene (C282Y and H63D) in type 2 diabetes mellitus (DM) patients and their possible association with diabetic chronic complications. METHODS:A case-control study with 723 subjects was performed. All diabetic subjects (n=519) underwent a clinical and laboratory e...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2009.12.002

    authors: Colli ML,Gross JL,Canani LH

    更新日期:2011-01-01 00:00:00

  • High-intensity statin therapy and regression of coronary atherosclerosis in patients with diabetes mellitus.

    abstract::Recommended low-density lipoprotein cholesterol (LDL-C) levels for patients with documented cardiovascular disease (CVD) are <100mg/dL (2.6mmol/l) with further reduction to <70mg/dL (1.8mmol/l) for higher-risk patients. High-intensity statin treatment may halt the progression as well as stabilize and induce regression...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/j.jdiacomp.2014.10.004

    authors: Athyros VG,Katsiki N,Karagiannis A,Mikhailidis DP

    更新日期:2015-01-01 00:00:00

  • Equal improvement in glycaemia with lixisenatide given before breakfast or the main meal of the day.

    abstract:AIMS:The aim of this study is to explore whether administration timing affects glycaemic control by lixisenatide once-daily in type 2 diabetes mellitus (T2DM). METHODS:A phase IIIb, open-label, 1:1 randomized, active-controlled, 24-week multicentre study of T2DM patients inadequately controlled on metformin was conduc...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jdiacomp.2014.05.012

    authors: Ahrén B,Vorokhobina N,Souhami E,Demil N,Ye J,Aronson R

    更新日期:2014-09-01 00:00:00

  • Paecilomyces varioti pneumonia in a patient with diabetes mellitus.

    abstract::Paecilomyces is a saprophytic soil fungus that is an uncommon human pathogen. We report a diabetic patient who developed an upper lobe pulmonary infection due to Paecilomyces varioti. This pneumonia responded poorly to oral imidazole therapy with ketoconazole. Eventual treatment of the chronic infiltrating process req...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(92)90027-i

    authors: Byrd RP Jr,Roy TM,Fields CL,Lynch JA

    更新日期:1992-04-01 00:00:00

  • Effects of eicosapentaenoic acid on platelet activation markers and cell adhesion molecules in hyperlipidemic patients with Type 2 diabetes mellitus.

    abstract::We compared the levels of microparticles, platelet activation markers, soluble cell adhesion molecules, soluble selectins, and antioxidized low-density lipoprotein (anti-Ox LDL) antibody between patients with hyperlipidemia and control subjects. Binding of anti-glycoprotein (GP) IIb/IIIa and anti-GPIb monoclonal antib...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(02)00172-1

    authors: Nomura S,Kanazawa S,Fukuhara S

    更新日期:2003-05-01 00:00:00

  • Paraoxonase 1 gene polymorphisms concerning non-insulin-dependent diabetes mellitus nephropathy in hemodialysis patients.

    abstract:AIMS:Data on involvement of paraoxonase 1 gene (PON1) in non-insulin-dependent diabetes mellitus (NIDDM) nephropathy are scarce. We investigated PON1 polymorphisms concerning end-stage NIDDM nephropathy and atherosclerotic complications in NIDDM nephropathy patients treated with hemodialysis (HD). METHODS:In NIDDM nep...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107687

    authors: Grzegorzewska AE,Ostromecka K,Adamska P,Mostowska A,Warchoł W,Jagodziński PP

    更新日期:2020-11-01 00:00:00

  • Diabetes Complications Severity Index (DCSI)-Update and ICD-10 translation.

    abstract:AIMS:The Diabetes Complications Severity Index (DCSI) converts diagnostic codes and laboratory results into a 14-level metric quantifying the long-term effects of diabetes on seven body systems. Adoption of the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) necessitates tran...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.02.018

    authors: Glasheen WP,Renda A,Dong Y

    更新日期:2017-06-01 00:00:00

  • Preserved tissue-type plasminogen activator release and endothelium-dependent vasodilation in postmenopausal women with NIDDM.

    abstract::We have recently shown that the net release of tissue-type plasminogen activator (t-PA) antigen can be rapidly enhanced by the muscarinic receptor stimulation in healthy males. Since diabetes mellitus has been associated with endothelial dysfunction, the aim of the present study was to compare the endothelium-derived ...

    journal_title:Journal of diabetes and its complications

    pub_type: 临床试验,杂志文章

    doi:10.1016/s1056-8727(00)00058-1

    authors: Manhem K,Dotevall A,Wilhelmsen L,Jern S

    更新日期:2000-05-01 00:00:00

  • Prevalence of osteoporosis and vertebral fractures in postmenopausal women with type 2 diabetes mellitus and their relationship with duration of the disease and chronic complications.

    abstract:UNLABELLED:Controversial data suggest that patients with type 2 diabetes mellitus have an increased risk of fractures despite having, in some studies, higher bone mineral density. METHODS:The aim of this study was to determine the prevalence of osteoporosis and morphometric vertebral fractures in 148 postmenopausal di...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2011.02.004

    authors: Viégas M,Costa C,Lopes A,Griz L,Medeiro MA,Bandeira F

    更新日期:2011-07-01 00:00:00

  • The ischemic etiology of heart failure in diabetics limits reverse left ventricular remodeling after cardiac resynchronization therapy.

    abstract:AIM OF THE STUDY:The aim of this study was to evaluate reverse volumetric left ventricular (LV) remodeling after cardiac resynchronization therapy (CRT) in patients with heart failure (HF) with vs. without diabetes mellitus (DM). METHODS:The study comprised 130 consecutive patients with HF (mean age, 61+/-12 years) wh...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2008.04.003

    authors: Soliman OI,van Dalen BM,Theuns DA,ten Cate FJ,Nemes A,Jordaens LJ,Geleijnse ML

    更新日期:2009-09-01 00:00:00

  • Skeletal muscle lipoprotein-lipase activity in insulin-dependent diabetic patients with and without albuminuria.

    abstract::In patients with insulin-dependent diabetes mellitus (IDDM), albuminuria reflects widespread vascular dysfunction. Albuminuria has been associated to defects of heparan sulfate proteoglycan (HSPG) within the extracellular matrix. Our hypothesis is that loss of HSPG in vascular walls reduces the HSPG-bound lipoprotein-...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(96)00048-7

    authors: Hansen PM,Jensen T,Egeberg J,Lithell H,Kofoed-Enevoldsen A,Deckert T

    更新日期:1997-07-01 00:00:00

  • Prevalence of osteoporosis and factors affecting bone mineral density among postmenopausal Turkish women with type 2 diabetes.

    abstract:OBJECTIVES:Controversy remains as to the effects of type 2 diabetes on bone metabolism. The aims of this study were to assess the association between type 2 diabetes and bone mineral density (BMD) and to evaluate the possible relationship between chronic diabetic complications and bone density. METHODS:Bone mineral de...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2007.06.004

    authors: Anaforoglu I,Nar-Demirer A,Bascil-Tutuncu N,Ertorer ME

    更新日期:2009-01-01 00:00:00

  • Using Tc-99m DMSA renal cortex scan to detect renal damage in women with type 2 diabetes.

    abstract::Women with diabetes mellitus (DM) have urinary tract infection (UTI) more often than women without DM. It is unknown, however, what the prevalence and type of renal damage due to UTI is in these women. Therefore, in this study, we compared type 2 DM women with or without UTI history for the prevalence and type of rena...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(02)00222-2

    authors: Wu HC,Chang CH,Lai MM,Lin CC,Lee CC,Kao A

    更新日期:2003-09-01 00:00:00

  • The Haptoglobin genotype predicts cardio-renal mortality in type 1 diabetes.

    abstract:AIMS:The Haptoglobin (HP) 2-2 genotype increases cardiovascular diabetes complication incidence. In type 1 diabetes, HP 2-2 also predicts declining kidney function and end-stage renal disease. We investigated whether HP 2-2 predisposes to cardio-renal mortality, while considering other causes of death as competing risk...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.11.011

    authors: Costacou T,Orchard TJ

    更新日期:2016-03-01 00:00:00

  • Urinary excretion rate of NC1 and Tamm-Horsfall protein in the microalbuminuric type I diabetic patient.

    abstract::Fifty-six type I diabetic patients with microalbuminuria (albumin excretion rate 20-200 micrograms/min) were characterized as to sex, age, duration of diabetes, smoking habits, blood pressure, glomerular filtration rate, urinary NC1 (the carboxy-terminal domain of collagen IV), and Tamm-Horsfall protein excretion rate...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/1056-8727(94)90055-8

    authors: Torffvit O,Agardh CD

    更新日期:1994-04-01 00:00:00

  • Maximum BMI and microvascular complications in a cohort of Japanese patients with type 2 diabetes: the Japan Diabetes Complications Study.

    abstract:AIMS:The aim of this study was to examine the associations between possible indices of obesity based on information on weight history and the incidence of microvascular complications. METHODS:A cohort of individuals with type 2 diabetes from 59 institutes in Japan was followed for 8years. Patients were classified into...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jdiacomp.2016.02.020

    authors: Tanaka S,Tanaka S,Iimuro S,Ishibashi S,Yamashita H,Moriya T,Katayama S,Akanuma Y,Ohashi Y,Yamada N,Araki A,Ito H,Sone H,Japan Diabetes Complications Study Group.

    更新日期:2016-07-01 00:00:00

  • Undiagnosed cognitive impairment, health status and depressive symptoms in patients with type 2 diabetes.

    abstract:AIMS:Type 2 diabetes (T2DM) is associated with cognitive impairment. We examined whether undiagnosed cognitive impairment in T2DM-patients is associated with a reduced health status and depressive symptoms. METHODS:In an observational study, 225 T2DM-patients aged ≥70years were examined at their homes and (some of the...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.07.010

    authors: Koekkoek PS,Biessels GJ,Kooistra M,Janssen J,Kappelle LJ,Rutten GE,Cog-ID study group.

    更新日期:2015-11-01 00:00:00

  • Awareness of hypoglycemia and spectral analysis of heart rate variability in type 1 diabetes.

    abstract:AIMS:To investigate the relationship of unawareness of hypoglycemia with spectral analysis of heart rate variability (HRV) and clinical variables in type 1 diabetes (T1D) individuals. METHODS:Participants with type 1 diabetes mellitus (type 1 diabetes) were prospectively assessed for hypoglycemia awareness using the P...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107617

    authors: Paes T,Rolim LC,Filho CS,de Sa JR,Dib SA

    更新日期:2020-08-01 00:00:00

  • Validation of the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire and its correlation with visual analog pain scales in Greek population.

    abstract:INTRODUCTION:One of the diagnostic tools of neuropathetic pain (NP) relies on screening questionnaires including the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire. AIM:To apply and validate the LANSS questionnaire in Greek population. To assess any correlation between LANSS score and visual ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.08.008

    authors: Spanos K,Lachanas VA,Chan P,Bargiota A,Giannoukas AD

    更新日期:2015-11-01 00:00:00

  • The impact of sensory and/or sensorimotor neuropathy on lower limb muscle endurance, explosive and maximal muscle strength in patients with type 2 diabetes mellitus.

    abstract:AIMS:The purpose of this study was to investigate the impact of diabetic neuropathy (dNP) on lower limb endurance, explosive and maximal muscle strength in patients with Type 2 Diabetes Mellitus (T2DM). METHODS:Fifty-four participants, aged between 55 and 85, were enrolled in this observational comparative study. The ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2020.107562

    authors: Van Eetvelde BLM,Lapauw B,Proot P,Vanden Wyngaert K,Celie B,Cambier D,Calders P

    更新日期:2020-06-01 00:00:00

  • Association between diabetes mellitus and hearing impairment in American and Korean populations.

    abstract:AIMS:The aim of this study was to evaluate ethnic- and sex-specific associations between DM and hearing impairment. METHODS:For this cross-sectional study using National Health and Nutrition Examination Survey in the U.S. and Korea, the total number of eligible participants included was 7081 in the U.S. and 15,704 in ...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2018.04.004

    authors: Moon S,Park JH,Yu JM,Choi MK,Yoo HJ

    更新日期:2018-07-01 00:00:00

  • Stratifying healthcare costs using the Diabetes Complication Severity Index.

    abstract:OBJECTIVE:We aim to determine whether healthcare costs for patients diagnosed with Type 2 Diabetes Mellitus (T2DM) are associated with the severity of diabetes complications as measured by the Diabetes Complication Severity Index (DCSI). METHODS:Retrospective cohort analysis was performed on a 2007 primary care cohort...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2012.02.004

    authors: Wu CX,Tan WS,Toh MP,Heng BH

    更新日期:2012-03-01 00:00:00

  • Retrospective analysis of safety and efficacy of liraglutide monotherapy and sulfonylurea-combination therapy in Japanese type 2 diabetes: Association of remaining β-cell function and achievement of HbA1c target one year after initiation.

    abstract:AIMS:The GLP-1 receptor agonist liraglutide improves impaired pancreatic β-cell function, thereby exerting glucose-lowering effects. However, the association of remaining β-cell function with long-term therapeutic efficacy of liraglutide remains largely unknown. METHODS:Patients with type 2 diabetes who started liragl...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2015.07.020

    authors: Usui R,Yabe D,Kuwata H,Murotani K,Kurose T,Seino Y

    更新日期:2015-11-01 00:00:00

  • Hemobiological properties of gliclazide.

    abstract::Non-insulin-dependent diabetes mellitus (NIDDM) is associated with an increased risk of macro- and microvascular degenerative complications. Gliclazide is a second generation sulfonylurea that is widely used in the treatment of type II diabetes mellitus. Its hypoglycemic activity is well documented. In addition to its...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/1056-8727(94)90050-7

    authors: Ziegler O,Drouin P

    更新日期:1994-10-01 00:00:00

  • The prevalence of incipient tubular dysfunction, but not of glomerular dysfunction, is increased in patients with diabetes onset in childhood.

    abstract::The study investigated the prevalence of incipient renal dysfunction in two cohorts with identical duration of type I diabetes but with childhood or adult onset of the disease. The pattern of glomerular (albumin, alb) and tubular (alpha(1)-microglobulin, alpha(1)-m, and N-acetyl-beta-D-glucosaminidase, NAG) urinary pr...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(99)00055-0

    authors: Kordonouri O,Kahl A,Jörres A,Hopfenmüller W,Müller C,Danne T

    更新日期:1999-09-01 00:00:00

  • Hypomagnesemia is linked to low serum HDL-cholesterol irrespective of serum glucose values.

    abstract::Hypomagnesemia is common in diabetic subjects, and is especially common in poorly controlled diabetes, suggesting that diabetes low serum magnesium status is osmotic diuresis-dependent. To assess the relationship between serum magnesium and HDL-cholesterol concentration adjusted by serum glucose values. We assessed th...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/s1056-8727(00)00127-6

    authors: Guerrero-Romero F,Rodríguez-Morán M

    更新日期:2000-09-01 00:00:00

  • Extracellular matrix and its interactions in the diabetic kidney: a molecular biological approach.

    abstract::Increased extracellular matrix (ECM) is the ultrastructural hallmark of diabetic microangiopathy. Its accumulation within the kidney is directly linked to the clinical manifestations of diabetic nephropathy, namely proteinuria and declining renal function. The pathogenesis of ECM changes in diabetes is not well unders...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章,评审

    doi:10.1016/1056-8727(95)80015-7

    authors: Gilbert RE,Cox A,Dziadek M,Cooper ME,Jerums G

    更新日期:1995-10-01 00:00:00

  • Comparison of traditional diabetes risk scores and HbA1c to predict type 2 diabetes mellitus in a population based cohort study.

    abstract:AIMS:Compare performances of diabetes risk scores and glycated hemoglobin (HbA1c) to estimate the risk of incident type 2 diabetes mellitus (T2DM) in Northeast Germany. METHODS:We studied 2916 subjects (20 to 81years) from the Study of Health in Pomerania (SHIP) in a 5-year follow-up period. Diabetes risk scores inclu...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.07.016

    authors: Krabbe CEM,Schipf S,Ittermann T,Dörr M,Nauck M,Chenot JF,Markus MRP,Völzke H

    更新日期:2017-11-01 00:00:00

  • The 1h post glucose value best predicts future dysglycemia among normal glucose tolerance subjects.

    abstract:AIM:To analyse the OGTT glycemic parameters - fasting, 1h and 2h plasma glucose values singly and in various combinations; with respect to their prediction of future dysglycemia in subjects with normal glucose tolerance (NGT). METHODS:Electronic medical records of individuals who underwent an OGTT between 1991 and 201...

    journal_title:Journal of diabetes and its complications

    pub_type: 杂志文章

    doi:10.1016/j.jdiacomp.2017.07.017

    authors: Sai Prasanna N,Amutha A,Pramodkumar TA,Anjana RM,Venkatesan U,Priya M,Pradeepa R,Mohan V

    更新日期:2017-11-01 00:00:00