Abstract:
:Drug shortages have become all too familiar in the health care environment, with over 200 drugs currently on shortage. In the wake of Hurricane Maria in September 2017, hospitals across the USA had to quickly and creatively adjust medication preparation and administration techniques in light of decreased availability of intravenous (IV) bags used for compounding a vast amount of medications. Amino acid preparations, essential for compounding parenteral nutrition, were also directly impacted by the hurricane. Upon realization of the impending drug shortages, hospitals resorted to alternative methods of drug administration, such as IV push routes, formulary substitutions, or alternative drug therapies in hopes of preserving the small supply of IV bags available and prioritizing them for them most critical needs. In some cases, alternative drug therapies were required, which increased the risk of medication errors due to the use of less-familiar treatment options. Clinical pharmacists rounding with medical teams provided essential, patient-specific drug regimen alternatives to help preserve a dwindling supply while ensuring use in the most critical cases. Drug shortages also frequently occur in the setting of manufacturing delays or discontinuation and drug recalls, with potential to negatively impact patient care. The seriousness of the drug shortage crisis reached public attention by December 2017, when political and pharmacy organizations called for response to the national drug shortage crisis. In this article, we review institutional mitigation strategies in response to drug shortages and discuss downstream effects of these shortages, focusing on medications commonly prescribed in neurocritical care patients.
journal_name
Neurocrit Carejournal_title
Neurocritical careauthors
Clark SL,Levasseur-Franklin K,Pajoumand M,Barra M,Armahizer M,Patel DV,Wyatt Chester K,Tully APdoi
10.1007/s12028-019-00730-7subject
Has Abstractpub_date
2020-02-01 00:00:00pages
226-237issue
1eissn
1541-6933issn
1556-0961pii
10.1007/s12028-019-00730-7journal_volume
32pub_type
杂志文章,评审abstract::Advanced hemodynamic monitoring is necessary for many patients with acute brain and/or spinal cord injury. Optimizing cerebral and systemic physiology requires multi-organ system function monitoring. Hemodynamic manipulations are cardinal among interventions to regulate cerebral perfusion pressure and cerebral blood f...
journal_title:Neurocritical care
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doi:10.1007/s12028-011-9568-x
更新日期:2012-02-01 00:00:00
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journal_title:Neurocritical care
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journal_title:Neurocritical care
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journal_title:Neurocritical care
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journal_title:Neurocritical care
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journal_title:Neurocritical care
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doi:10.1007/s12028-007-0040-x
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journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1007/s12028-013-9872-8
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journal_title:Neurocritical care
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pub_type: 历史文章,杂志文章
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journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-020-01140-w
更新日期:2020-11-10 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-009-9251-7
更新日期:2009-12-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-018-0631-8
更新日期:2019-04-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-007-9045-8
更新日期:2008-01-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-008-9064-0
更新日期:2008-01-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
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更新日期:2010-02-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-019-00713-8
更新日期:2020-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2021-01-25 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章,评审
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更新日期:2018-06-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
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更新日期:2011-04-01 00:00:00
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更新日期:2011-04-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章,评审
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更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2019-02-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章,评审
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journal_title:Neurocritical care
pub_type: 杂志文章
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journal_title:Neurocritical care
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:Neurocritical care
pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00