Eligibility for the surgical trial in intracerebral hemorrhage II study in a population-based cohort.

Abstract:

INTRODUCTION:No proven treatments exist for intracerebral hemorrhage (ICH). Carefully selected patients may benefit from surgery, and an international multicenter trial is ongoing. We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria. METHODS:We identified all patients aged > or =18 years residing in the five-county Greater Cincinnati region who were hospitalized with first-ever nontraumatic ICH in 2005. STICH II trial criteria were used to determine eligibility for treatment and reasons for exclusion. RESULTS:During 2005, 286 ICH patients were identified (103 lobar, 126 deep cerebral, 23 brainstem, 28 cerebellar, and 6 IVH). Non-lobar hemorrhages are not eligible for STICH II. Among patients with lobar hemorrhage, 22 had no exclusions. The most common (not mutually exclusive) reasons for exclusion were volume <10 cc or >100 cc (n = 46) and presence of IVH (n = 27). No significant age, gender or racial differences existed between eligible and ineligible patients with lobar ICH. Only one (4.5%) of the 22 STICH II eligible patients in our population had surgery, compared with eight of 81 (9.9%) ineligible lobar ICH patients (P = 0.43). Mortality at 180 days in STICH II eligible patients was 36% vs. 49% for ineligible lobar ICH patients (P = 0.19). CONCLUSIONS:In this population-based ICH cohort, 7.7% (22 of 286) of ICH patients would have qualified for STICH II enrollment. Other treatment options need to be explored for most ICH patients.

journal_name

Neurocrit Care

journal_title

Neurocritical care

authors

Adeoye O,Woo D,Haverbusch M,Tao H,Sekar P,Moomaw CJ,Shutter L,Kleindorfer D,Kissela B,Broderick J,Flaherty ML

doi

10.1007/s12028-007-9045-8

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

237-41

issue

2

eissn

1541-6933

issn

1556-0961

journal_volume

9

pub_type

杂志文章
  • New Approaches to Critical Illness Polyneuromyopathy: High-Resolution Neuromuscular Ultrasound Characteristics and Cytokine Profiling.

    abstract:BACKGROUND:Diagnosis of intensive care unit acquired weakness (ICUAW) is challenging. Pathogenesis of underlying critical illness polyneuromyopathy (CIPNM) remains incompletely understood. This exploratory study investigated whether longitudinal neuromuscular ultrasound examinations and cytokine analyses in correlation...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-020-01148-2

    authors: Fisse AL,May C,Motte J,Pedreiturria X,Breuer TGK,Schneider-Gold C,Marcus K,Gold R,Yoon MS,Pitarokoili K

    更新日期:2020-11-24 00:00:00

  • Effect of Desmopressin on Platelet Dysfunction During Antiplatelet Therapy: A Systematic Review.

    abstract:BACKGROUND AND OBJECTIVE:An increasing number of patients receive antiplatelet therapy. Patients exposed to surgery while receiving platelet inhibitors hold an increased bleeding risk. Especially in neurosurgery and neurocritical care patients, bleeding and hematoma expansion are feared complications as even minor blee...

    journal_title:Neurocritical care

    pub_type: 杂志文章,评审

    doi:10.1007/s12028-020-01055-6

    authors: Andersen LK,Hvas AM,Hvas CL

    更新日期:2020-08-04 00:00:00

  • Continuous EEG in a Pediatric Intensive Care Unit: Adherence to Monitoring Criteria and Barriers to Adequate Implementation.

    abstract:BACKGROUND:Subclinical seizures are common in critically ill children and are best detected by continuous EEG (cEEG) monitoring. Timely detection of seizures requires pediatric intensive care unit (PICU) physicians to identify patients at risk of seizures and request cEEG monitoring. A recent consensus statement from t...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-020-01053-8

    authors: Ghossein J,Alnaji F,Webster RJ,Bulusu S,Pohl D

    更新日期:2020-07-21 00:00:00

  • Anesthetic management of the pregnant patient for endovascular coiling of an unruptured intracranial aneurysm.

    abstract::Diagnosis of an intracranial aneurysm during pregnancy is a rare event requiring multidisciplinary care for successful management. The knowledge base for the anesthesiologist involves principles of both obstetric and neuroanesthesia, as well as critical care. This article reports such a case and discusses the relevant...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1385/NCC:4:1:018

    authors: Allen G,Farling P,McAtamney D

    更新日期:2006-01-01 00:00:00

  • Increased CSF concentrations of myelin basic protein after TBI in infants and children: absence of significant effect of therapeutic hypothermia.

    abstract:BACKGROUND:The objectives of this study were to determine effects of severe traumatic brain injury (TBI) on cerebrospinal fluid (CSF) concentrations of myelin basic protein (MBP) and to assess relationships between clinical variables and CSF MBP concentrations. METHODS:We measured serial CSF MBP concentrations in chil...

    journal_title:Neurocritical care

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12028-012-9767-0

    authors: Su E,Bell MJ,Kochanek PM,Wisniewski SR,Bayir H,Clark RS,Adelson PD,Tyler-Kabara EC,Janesko-Feldman KL,Berger RP

    更新日期:2012-12-01 00:00:00

  • Electroencephalography in survivors of cardiac arrest: comparing pre- and post-therapeutic hypothermia eras.

    abstract::Electroencephalography in the setting of hypothermia and anoxia has been studied in humans since the 1950s. Specific patterns after cardiac arrest have been associated with prognosis since the 1960s, with several prognostic rating scales developed in the second half of the twentieth century. In 2002, two pivotal clini...

    journal_title:Neurocritical care

    pub_type: 杂志文章,评审

    doi:10.1007/s12028-014-0018-4

    authors: Crepeau AZ,Britton JW,Fugate JE,Rabinstein AA,Wijdicks EF

    更新日期:2015-02-01 00:00:00

  • The effect of transfer and hospital volume in subarachnoid hemorrhage patients.

    abstract:INTRODUCTION:Prompt management of aneurysmal subarachnoid hemorrhage (SAH) is critical. Literature is inconclusive regarding outcomes for patients directly admitted to specialized centers versus transferred from lower-volume hospitals. Providers are often unclear about the safety of transferring critical patients. This...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-012-9740-y

    authors: Nuño M,Patil CG,Lyden P,Drazin D

    更新日期:2012-12-01 00:00:00

  • Argon Inhalation for 24 h After Closed-Head Injury Does not Improve Recovery, Neuroinflammation, or Neurologic Outcome in Mice.

    abstract:BACKGROUND/OBJECTIVE:In recent years, the noble gas argon (Ar) has been extensively studied for its organ protection properties. While mounting in vitro and in vivo evidence indicates that argon provides neuroprotection in ischemic brain injury, its neuroprotective potential in traumatic brain injury (TBI) has not been...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-020-01104-0

    authors: Creed J,Cantillana-Riquelme V,Yan BH,Ma S,Chu D,Wang H,Turner DA,Laskowitz DT,Hoffmann U

    更新日期:2020-09-21 00:00:00

  • Lipid Peroxidation and Antioxidant Consumption as Early Markers of Neurosurgery-Related Brain Injury in Children.

    abstract:BACKGROUND AND AIMS:Lipid peroxidation represents a marker of secondary brain injury both in traumatic and in non-traumatic conditions-as in major neurosurgical procedures-eventually leading to brain edema amplification and further brain damage. Malondialdehyde (MDA), a lipid peroxidation marker, and ascorbate, a marke...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-019-00870-w

    authors: Piastra M,Caresta E,Massimi L,Picconi E,Luca E,Morena TC,Conti G,Eaton S

    更新日期:2020-08-01 00:00:00

  • Attitudes of Nurses Toward Disability and Treatment in Space-Occupying Middle Cerebral Artery Stroke.

    abstract:BACKGROUND:Attitudes toward the degree of acceptable disability and the importance of aphasia are critical in deciding on decompressive hemicraniectomy (DHC) in space-occupying middle cerebral artery stroke (SOS). The attitudes of nurses deserve strong attention, because of their close interaction with patients during ...

    journal_title:Neurocritical care

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s12028-018-0586-9

    authors: Neugebauer H,Malakou F,Uttner I,Köpke M,Jüttler E,IGNITE Study Group (Initiative of German NeuroIntensive Trial Engagement).

    更新日期:2019-02-01 00:00:00

  • Expansion-Prone Hematoma: Defining a Population at High Risk of Hematoma Growth and Poor Outcome.

    abstract:BACKGROUND:Noncontrast computed tomography (CT) markers are increasingly used for predicting hematoma expansion. The aim of our study was to investigate the predictive value of expansion-prone hematoma in predicting hematoma expansion and outcome in patients with intracerebral hemorrhage (ICH). METHODS:Between July 20...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-018-0644-3

    authors: Li Q,Shen YQ,Xie XF,Xue MZ,Cao D,Yang WS,Li R,Deng L,Wei M,Lv FJ,Wu GF,Tang ZP,Xie P

    更新日期:2019-06-01 00:00:00

  • High-dose intra-arterial nicardipine results in hypotension following vasospasm treatment in subarachnoid hemorrhage.

    abstract:BACKGROUND:Intra-arterial (IA) nicardipine is often used to treat cerebral vasospasm associated with subarachnoid hemorrhage (SAH). While hypotension has been noted to be a dose-limiting side effect of intravenous infusions, this has seldom been reported for IA administration. METHODS:We reviewed a consecutive series ...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-011-9537-4

    authors: Rosenberg N,Lazzaro MA,Lopes DK,Prabhakaran S

    更新日期:2011-12-01 00:00:00

  • High Serum DNA and RNA Oxidative Damage in Non-surviving Patients with Spontaneous Intracerebral Hemorrhage.

    abstract:PURPOSE:One study found higher leukocytes 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels in patients with spontaneous intracerebral hemorrhage (ICH) than in healthy subjects due to the oxidation of guanosine from deoxyribonucleic acid (DNA). The objective of this study was to determine whether there is an association betw...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-019-00864-8

    authors: Lorente L,Martín MM,González-Rivero AF,Pérez-Cejas A,Abreu-González P,Sabatel R,Ramos L,Argueso M,Cáceres JJ,Solé-Violán J,Jiménez A,García-Marín V

    更新日期:2020-08-01 00:00:00

  • Comparison of Three Point-of-Care Ultrasound Views and MRI Measurements for Optic Nerve Sheath Diameter: A Prospective Validity Study.

    abstract:INTRODUCTION:Point-of-care ultrasound of the optic nerve sheath diameter (ONSD) to diagnose increased intracranial pressure (ICP) is of great interest in various clinical scenarios. Yet, the lack of examination standardization has made clinical utility difficult. We compare three ultrasound ocular plane views (inferior...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-019-00881-7

    authors: Raval R,Shen J,Lau D,Ferguson N,Kelly T,Daniels J,Dorotta I,Ramsingh D

    更新日期:2020-08-01 00:00:00

  • The Future of Neurocritical Care Research: Proceedings and Recommendations from the Fifth Neurocritical Care Research Network Conference.

    abstract::The Fifth Neurocritical Care Research Network (NCRN) Conference held in Boca Raton, Florida, in September of 2018 was devoted to challenging the current status quo and examining the role of the Neurocritical Care Society (NCS) in driving the science and research of neurocritical care. The aim of this in-person meeting...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-019-00767-8

    authors: Hocker S,Shah S,Vespa P,Provencio JJ,Calvillo E,Olson DM,Venkatasubba Rao CP,Hemphill JC 3rd,Helbok R,Human T,Kamel H,Madden LK,Nyquist P,Bentho O,O'Phelan K,Lewin JJ 3rd,Alexander S,Ziai W,Chou SH,Rincon F,McNett

    更新日期:2020-02-01 00:00:00

  • Significance of a reduced cerebral blood flow during the first 12 hours after traumatic brain injury.

    abstract:BACKGROUND:It is controversial whether a low cerebral blood flow (CBF) simply reflects the severity of injury or whether ischemia contributes to the brain's injury. It is also not clear whether posttraumatic cerebral hypoperfusion results from intracranial hypertension or from pathologic changes of the cerebral vascula...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1385/NCC:1:1:69

    authors: Hlatky R,Contant CF,Diaz-Marchan P,Valadka AB,Robertson CS

    更新日期:2004-01-01 00:00:00

  • Intranasal perfluorochemical spray for preferential brain cooling in sheep.

    abstract:INTRODUCTION:Hypothermic brain protection has been linked to how rapidly cooling is initiated and how quickly and uniformly the therapeutic hypothermic zone (THZ) is reached. The nasopharyngeal (NP) approach is uniquely suited for preferential brain cooling due to anatomic proximity to the cerebral circulation, caverno...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-008-9064-0

    authors: Wolfson MR,Malone DJ,Wu J,Hoffman J,Rozenberg A,Shaffer TH,Barbut D

    更新日期:2008-01-01 00:00:00

  • Cefepime-induced nonconvulsive status epilepticus: case report and review.

    abstract:INTRODUCTION:A case of cefepime-induced nonconvulsive status epilepticus in a 15-year-old child with end stage renal disease on hemodialysis is reported. Clinical symptoms and EEG dramatically improved 48 h after discontinuation of cefepime. METHODS:Twenty-five cases of nonconvulsive status epilepticus associated with...

    journal_title:Neurocritical care

    pub_type: 杂志文章,评审

    doi:10.1007/s12028-008-9166-8

    authors: Thabet F,Al Maghrabi M,Al Barraq A,Tabarki B

    更新日期:2009-01-01 00:00:00

  • Autoimmune Encephalitis at the Neurological Intensive Care Unit: Etiologies, Reasons for Admission and Survival.

    abstract:BACKGROUND:Early recognition and treatment of autoimmune encephalitis (AE) has become an essential issue in clinical practice. However, little is known about patients with deteriorating conditions and the need for intensive care treatment. Here, we aimed to characterize underlying aetiologies, clinical symptoms, reason...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-016-0370-7

    authors: Harutyunyan G,Hauer L,Dünser MW,Karamyan A,Moser T,Pikija S,Leitinger M,Novak HF,Trinka E,Sellner J

    更新日期:2017-08-01 00:00:00

  • Boomerang sign on MRI.

    abstract:INTRODUCTION:Altered mental status and more subtle cognitive and personality changes after traumatic brain injury (TBI) are pervasive problems in patients who survive initial injury. MRI is not necessarily part of the diagnostic evaluation of these patients. METHODS:Case report with relevant image and review of the li...

    journal_title:Neurocritical care

    pub_type: 杂志文章,评审

    doi:10.1007/s12028-012-9699-8

    authors: Hirsch KG,Hoesch RE

    更新日期:2012-06-01 00:00:00

  • Intracerebral Hemorrhage with Intraventricular Extension Associated with Loss of Consciousness at Symptom Onset.

    abstract:BACKGROUND:In patients with spontaneous intracerebral hemorrhage (ICH), pre-hospital markers of disease severity might be useful to potentially triage patients to undergo early interventions. OBJECTIVE:Here, we tested whether loss of consciousness (LOC) at the onset of ICH is associated with intraventricular hemorrhag...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-020-01180-2

    authors: Witsch J,Falcone GJ,Leasure AC,Matouk C,Endres M,Sansing L,Woo D,Sheth KN

    更新日期:2021-01-21 00:00:00

  • Unilateral third nerve palsy caused by Guillain-Barré Syndrome.

    abstract:BACKGROUND:Highly asymmetric clinical signs in a patient suggest the need for caution in making the diagnosis of Guillain-Barré Syndrome (GBS). METHODS:Case report and literature review. We present a case of strictly unilateral left third cranial nerve palsy in a patient with GBS, review other highly asymmetrical cran...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1385/NCC:1:4:461

    authors: St Louis EK,Jacobson DM

    更新日期:2004-01-01 00:00:00

  • Intraventricular nicardipine for refractory cerebral vasospasm after subarachnoid hemorrhage.

    abstract:INTRODUCTION:Delayed ischemic deficit from vasospasm is a leading cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage. Although several treatment modalities have been used to reverse the deleterious effects of vasospasm, alternative therapies are needed, as conventional therapies are often ineffec...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-007-9017-z

    authors: Goodson K,Lapointe M,Monroe T,Chalela JA

    更新日期:2008-01-01 00:00:00

  • Conivaptan, a Selective Arginine Vasopressin V1a and V2 Receptor Antagonist Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4.

    abstract:BACKGROUND:Cerebral edema is a major cause of mortality following cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). Arginine vasopressin (AVP) and water channel aquaporin-4 (AQP4) have been implicated in the pathogenesis of CA-evoked cerebral edema. In this study, we examined if conivaptan, a V1a and V2 anta...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-015-0236-4

    authors: Nakayama S,Amiry-Moghaddam M,Ottersen OP,Bhardwaj A

    更新日期:2016-04-01 00:00:00

  • Multifocal and recurrent subarachnoid hemorrhage due to an herbal supplement containing natural coumarins.

    abstract:INTRODUCTION:Over-the-counter herbal and alternative medicines are classified as dietary supplements and, unlike drugs, are not rigorously regulated by the United States Food and Drug Administration. Their potential adverse effects are often poorly characterized. METHOD:Red clover, dong quai, and Siberian ginseng are ...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-007-0075-z

    authors: Friedman JA,Taylor SA,McDermott W,Alikhani P

    更新日期:2007-01-01 00:00:00

  • Intra-aortic balloon pump counterpulsation in the setting of subarachnoid hemorrhage, cerebral vasospasm, and neurogenic stress cardiomyopathy. Case report and review of the literature.

    abstract:BACKGROUND:The management of symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) can be often complicated by the presence of stunned myocardium and left ventricular failure. Vasopressors and inotropes are commonly used to optimize mean arterial pressure (MAP) and cerebral perfusion pressure (...

    journal_title:Neurocritical care

    pub_type: 杂志文章,评审

    doi:10.1007/s12028-010-9358-x

    authors: Lazaridis C,Pradilla G,Nyquist PA,Tamargo RJ

    更新日期:2010-08-01 00:00:00

  • Blood Pressure Guideline Adherence in Patients with Ischemic and Hemorrhagic Stroke in the Neurointensive Care Unit Setting.

    abstract:BACKGROUND AND PURPOSE:Patients with acute brain injuries require strict physiologic control to minimize morbidity and mortality. This study aimed to assess in-hospital compliance to strict physiologic parameters (BP, HR, ICP, SpO2) in these populations. METHODS:Patients with severe cerebrovascular events were admitte...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1007/s12028-015-0116-y

    authors: Porto GB,Spiotta AM,Chalela JA,Kellogg RT,Jauch EC

    更新日期:2015-12-01 00:00:00

  • Pharmacology and clinical use of recombinant activated factor seven in neurosciences.

    abstract::Recombinant activated factor VII (rFVIIa, NovoSeven, NovoNordisc, Danemark) has been approved for the treatment of patients with hemophilia with inhibitors, further indications, at least in some countries, include the treatment of factor VII deficiency and Glanzmann thrombasthenia refractory to conventional therapy. A...

    journal_title:Neurocritical care

    pub_type: 杂志文章,评审

    doi:10.1007/s12028-007-0006-z

    authors: Hartmann M,Sucker C

    更新日期:2007-01-01 00:00:00

  • Treatment of resistant fever: new method of local cerebral cooling.

    abstract:BACKGROUND:Fever in neurocritical care patients is common and has a negative impact on neurological outcome. The purpose of this prospective observational study was (1) to evaluate the practicability of cooling with newly developed neck pads in the daily setting of neurointensive care unit (NICU) patients and (2) to ev...

    journal_title:Neurocritical care

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12028-010-9451-1

    authors: Mink S,Schwarz U,Mudra R,Gugl C,Fröhlich J,Keller E

    更新日期:2011-08-01 00:00:00

  • Minor trauma may lead to traumatic internal carotid artery dissection.

    abstract::A farmer's wife was slapped by her cow's tail during milking. There was no obvious injury, but afterward she first developed unusual headaches of unknown origin and then a severe stroke 7 days later. Further diagnostics, including magnetic resonance imaging techniques, revealed a dissection of the carotid artery to be...

    journal_title:Neurocritical care

    pub_type: 杂志文章

    doi:10.1385/NCC:3:3:254

    authors: Huber R,Kassubek J

    更新日期:2005-01-01 00:00:00