Abstract：
BACKGROUND:There are some intracranial insults which are associated with cardiac abnormalities. Studies of these abnormalities have never been carried out in elective intracranial neurosurgery for the removal of brain tumors. Our prospective study aims at quantifying serum cardiac troponin T (cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) before and after elective intracranial neurosurgery for tumor resection in patients with no history of cardiac abnormality. METHODS:Pre- and postoperative serum cTnT and NT-proBNP were measured in 108 patients submitted to elective major intracranial surgery for the removal of neoplastic lesions. We tested potentially predictive models for these biomarker serum levels. RESULTS:cTnT was undetectable both before and after surgery. Median (IQR) basal NT-proBNP was 35 (18-69) pg/mL and 110 (51-191) pg/mL after surgery. In a multiple linear regression model, basal NT-proBNP was predicted by age, gender, BMI, and the presence of "mass effect" (midline shift or effaced perimesencephalic cisterns on preoperative CT scan) (whole model P < 0.0001; R (2) = 0.3502; and Adjusted R (2) = 0.3247). Postoperative NT-proBNP increase was predicted by baseline NT-proBNP level (whole model P < 0.0001; R (2) = 0.5106; and Adjusted R (2) = 0.5052). CONCLUSION:An intracranial mass effect is associated with higher NT-proBNP serum levels in patients with a brain neoplasm. Following elective intracranial surgery for brain tumor resection NT-proBNP values increase.
journal_name
Neurocrit Carejournal_title
Neurocritical careauthors
Ruggieri F,Gemma M,Calvi MR,Nicelli E,Agarossi A,Beretta Ldoi
10.1007/s12028-012-9684-2subject
Has Abstractpub_date
2012-12-01 00:00:00pages
395-400issue
3eissn
1541-6933issn
1556-0961journal_volume
17pub_type
杂志文章abstract：BACKGROUND:Subclinical seizures are common in critically ill children and are best detected by continuous EEG (cEEG) monitoring. Timely detection of seizures requires pediatric intensive care unit (PICU) physicians to identify patients at risk of seizures and request cEEG monitoring. A recent consensus statement from t...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-020-01053-8
更新日期：2020-07-21 00:00:00
abstract：BACKGROUND:Seizures are a common complication after intracerebral hemorrhage (ICH) but there is a substantial lack of information on the long-term incidence in ICH survivors and whether post-ICH seizures affect functional long-term outcome. METHODS:Over a five-year period 464 consecutive patients with spontaneous ICH ...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-014-9968-9
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Spontaneous intracranial hypotension (SIH) is a neurologic condition with the prototypical symptom of orthostatic headache. We report a dramatic case of SIH with life-threatening bilateral hygroma and uncal herniation. METHODS:Case report. RESULTS:A 44-year-old male patient presenting with orthostatic head...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-012-9783-0
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Infection is common following stroke and is independently associated with worse outcome. Clinical studies suggest that infections occur more frequently in those individuals with stroke-induced immunologic dysfunction. This study sought to explore the contribution of immunomodulatory cytokines and hormones to...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-010-9490-7
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Pneumocephalus is commonly encountered after neurosurgical procedures but can also be caused by craniofacial trauma and tumors of the skull base and rarely, can occur spontaneously. Contributing factors for the development of pneumocephalus include head position, duration of surgery, nitrous oxide (N(2)O) an...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-010-9363-0
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:Median nerve short-latency somatosensory evoked potentials (SSEPs) are useful in determining prognosis for awakening after coma following hypoxic ischemic encephalopathy, but reliability of interpretation is unclear. OBJECTIVE:To measure inter- and intra-observer reliability of determining presence or absen...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-009-9251-7
更新日期：2009-12-01 00:00:00
abstract：:Neuromuscular disorders increasingly are recognized as a complication in patients in the intensive care unit (ICU) and represent a common cause of prolonged ventilator dependency. The distinct syndromes of critical illness myopathy, prolonged neuromuscular blockade, and critical illness polyneuropathy (CIP) may arise ...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1385/NCC:3:3:195
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The indications for bevacizumab (a vascular endothelial growth factor inhibitor) have been expanded recently. Despite concerns for cerebrovascular events from bevacizumab treatment, detailed clinical and radiologic information are lacking. METHODS:Using the Mayo Clinic Rochester database (January 2006-Septe...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-011-9552-5
更新日期：2011-12-01 00:00:00
abstract：INTRODUCTION:Methylene blue (MB) infusion is frequently used to localize the parathyroid glands during parathyroidectomy and generally considered safe. Several recent reports suggest neurological toxicity and post-operative altered mental state typically after large dose infusions. The mechanism by which MB has neuroto...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-009-9206-z
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiologic entity, typically manifesting as reversible neurological symptoms and signs of white matter edema on magnetic resonance imaging. PRES has been widely described in adults. Studies of PRES in children are mostly limited ...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-019-00720-9
更新日期：2020-02-01 00:00:00
abstract：:Prophylactic use of hypervolemia and hypertension is believed to present an option to decrease the incidence of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage and improve neurologic outcome. A Medline literature search was conducted to review available evidence regarding volume management after subarac...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-011-9593-9
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Attitudes toward the degree of acceptable disability and the importance of aphasia are critical in deciding on decompressive hemicraniectomy (DHC) in space-occupying middle cerebral artery stroke (SOS). The attitudes of nurses deserve strong attention, because of their close interaction with patients during ...
journal_title：Neurocritical care
pub_type： 杂志文章,多中心研究
doi：10.1007/s12028-018-0586-9
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Stress-induced hyperglycemia (SIH) is the relative transient increase in glucose during a critical illness such as intracerebral hemorrhage (ICH) and is likely to play an important role in the pathogenesis of remote diffusion-weighted imaging (DWI) lesion (R-DWIL) in primary ICH. We sought to det...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-019-00747-y
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:There has been growing interest in the use of hypertonic sodium lactate (HSL) solution following traumatic brain injury (TBI) in humans. However, little is known about the effects of HSL on functional deficits with respect to the hyperosmotic nature of HSL. METHODS:We have compared the effects of HSL soluti...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-020-01090-3
更新日期：2020-09-09 00:00:00
abstract：BACKGROUND:Subarachnoid hemorrhage (SAH) is a devastating disease. Nimodipine is the only medical treatment shown to improve outcome of SAH patients. Human albumin (ALB) may exert neuroprotection in SAH. However, current usage of ALB in SAH is not known. We conducted an international survey of clinicians involved in th...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-013-9942-y
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:To date, common therapy in patients with intracranial hemorrhage (ICH) includes prophylaxis of seizure using antiepileptic drugs, commonly phenytoin. Phenytoin therapy is associated with a high incidence of cognitive disturbance. Levetiracetam is known to cause less cognitive disruption and may be a suitable...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-010-9341-6
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Terson's syndrome is intraocular hemorrhage (IOH) subsequent to subarachnoid hemorrhage (SAH). Its presence is associated with higher mortality in SAH. We report a case of Terson's syndrome and review the literature. CASE REPORT:A 71-year-old Caucasian gentleman collapsed and became comatose. Past medical h...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-011-9555-2
更新日期：2011-12-01 00:00:00
abstract：INTRODUCTION:Point-of-care ultrasound of the optic nerve sheath diameter (ONSD) to diagnose increased intracranial pressure (ICP) is of great interest in various clinical scenarios. Yet, the lack of examination standardization has made clinical utility difficult. We compare three ultrasound ocular plane views (inferior...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-019-00881-7
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:One study found higher leukocytes 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels in patients with spontaneous intracerebral hemorrhage (ICH) than in healthy subjects due to the oxidation of guanosine from deoxyribonucleic acid (DNA). The objective of this study was to determine whether there is an association betw...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-019-00864-8
更新日期：2020-08-01 00:00:00
abstract：INTRODUCTION:Dynamic testing of cerebral pressure autoregulation is more practical than static testing for critically ill patients. The process of cuff deflation is innocuous in the normal subject, but the systemic and cerebral effects of cuff deflation in severely head-injured patients have not been studied. The purpo...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1385/NCC:4:2:127
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Fever in neurocritical care patients is common and has a negative impact on neurological outcome. The purpose of this prospective observational study was (1) to evaluate the practicability of cooling with newly developed neck pads in the daily setting of neurointensive care unit (NICU) patients and (2) to ev...
journal_title：Neurocritical care
pub_type： 临床试验,杂志文章
doi：10.1007/s12028-010-9451-1
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Currently, continuous electroencephalographic monitoring (cEEG) is the only available diagnostic tool for continuous monitoring of brain function in intensive care unit (ICU) patients. Yet, the exact relevance of routinely applied ICU cEEG remains unclear, and information on the implementation of cEEG, espec...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-018-0525-9
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:Infection is the most common complication of external ventricular drain (EVD) placement. National trends in the annual incidence of meningitis among patients with traumatic brain injury (TBI) who have undergone EVD placement have not been reported. METHODS:The Nationwide Inpatient Sample was used ...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-018-0656-z
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Recombinant activated Factor VII (rFVIIa) has recently gained popularity for rapid reversal of coagulopathy during operative neurosurgery. Patients undergoing chronic subdural hematoma (CSDH) or epidural hematoma (EDH) evacuation often have their coagulation status judged by preoperative international normal...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-007-0040-x
更新日期：2007-01-01 00:00:00
abstract：:An elevated platelet count may occur during care of neurology/neurosurgical patients and is usually due to reactive or secondary thrombocytosis (ST) caused by inflammation or infection. Primary (clonal) thrombocythemia or essential thrombocythemia associated with myeloproliferative disorders is usually known before or...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-008-9076-9
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Hyponatremia may complicate brain injury and exacerbate cerebral edema and intracranial pressure (ICP). Vasopressin-receptor antagonists (such as conivaptan) are promising novel agents to treat hyponatremia that act by inducing aquaresis. It is unclear whether raising serum sodium in this way could also conf...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-010-9366-x
更新日期：2011-02-01 00:00:00
abstract：INTRODUCTION:Malignant cerebral edema develops in a small subset of patients with hemispheric strokes, precipitating deterioration and death if decompressive hemicraniectomy (DHC) is not performed in a timely manner. Predicting which stroke patients will develop malignant edema is imprecise based on clinical data alone...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-020-01056-5
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Abusive head trauma (AHT) is a common condition in children. Little is known in this condition regarding the frequency of seizures, the factors associated with increased risk of seizures, or the association of seizures with outcome. We sought to determine frequency and risks for in-hospital seizures after AH...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-010-9468-5
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Delayed ischemic neurological deficits (DINDs) contribute to morbidity and mortality following aneurysmal subarachnoid hemorrhage (SAH). Based on promising preliminary reports, some clinicians routinely administer statins to prevent DINDs. METHODS:Without language restriction, we searched MEDLINE, EMBASE, t...
journal_title：Neurocritical care
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s12028-009-9306-9
更新日期：2010-04-01 00:00:00
abstract：INTRODUCTION:Despite the recognized deleterious effects of hyperthermia on critically ill neurological patients, few investigations have studied hyperthermia after an ischemic stroke in the intensive care unit (ICU) setting. METHODS:Acute ischemic stroke patients admitted to the ICU were assigned to one of three group...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-008-9056-0
更新日期：2008-01-01 00:00:00
