Long-term persistence and adherence to blood pressure lowering agents among older Australians.

abstract：BACKGROUND:Granular clinical and laboratory data available in electronic health record (EHR) databases provide researchers the opportunity to conduct investigations that would not be possible in insurance claims databases; however, for pharmacoepidemiology studies, accurate classification of medication exposure is crit...

journal_title：Pharmacoepidemiology and drug safety

authors： Rowan CG,Flory J,Gerhard T,Cuddeback JK,Stempniewicz N,Lewis JD,Hennessy S

更新日期：2017-08-01 00:00:00

abstract：:The use of healthcare databases in research provides advantages such as increased speed, lower costs and limitation of some biases. However, database research has its own challenges as studies must be performed within the limitations of resources, which often are the product of complex healthcare systems. The primary ...

journal_title：Pharmacoepidemiology and drug safety

authors： Hall GC,Sauer B,Bourke A,Brown JS,Reynolds MW,LoCasale R

更新日期：2012-01-01 00:00:00

abstract：:The following article from Pharmacoepidemiology and Drug Safety, “Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery” by F. Krummenauer, S. Kurz and H.B. Dick, published online on July 11 2006 inWiley Online Library (wileyonlinelibrary.com), has...

journal_title：Pharmacoepidemiology and drug safety

authors：

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:Triptan medications are serotonin agonists used to treat migraine, a chronic pain condition highly prevalent in women of reproductive age. Data on the safety of triptans during pregnancy are scant. We sought to quantify the association of prenatal triptan exposure on neurodevelopment in 3-year-old children. ME...

journal_title：Pharmacoepidemiology and drug safety

authors： Wood ME,Frazier JA,Nordeng HM,Lapane KL

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:In this study, we analyzed the consumption trends of antihypertensives in Morocco during the 1991-2010 period and the impacts after the institution of Mandatory Health Insurance and the marketing of generic drugs. METHODS:We used sales data from the Moroccan subsidiary of IMS Health "Intercontinental Marketing...

journal_title：Pharmacoepidemiology and drug safety

authors： Berrada El Azizi G,Ahid S,Ghanname I,Belaiche A,Hassar M,Cherrah Y

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:The objective of this study was to quantify rates of adverse events in a high-risk multi-morbid population of institutionalized patients with Alzheimer's disease (AD). METHODS:We conducted a retrospective cohort study among nursing home residents diagnosed with AD and psychosis during January 1998 to October 1...

journal_title：Pharmacoepidemiology and drug safety

authors： Oliveria SA,Liperoti R,L'italien G,Pugner K,Safferman A,Carson W,Lapane K

更新日期：2006-11-01 00:00:00

abstract：:It is surprising to see how consumer Adverse Drug Reaction (ADR) reports have been continuously increasing for the last few years in Europe. This probably results from the influence of United States (US) market where the patients feels justified in telephoning the pharmaceutical companies directly with queries regardi...

journal_title：Pharmacoepidemiology and drug safety

authors： Fleuranceau-Morel P

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Non-adherence is considered a major barrier to better outcomes of diabetes care. A relationship has been established between polypharmacy and patients' adherence. This study aims to investigate the occurrence of polypharmacy and non-adherence in general practice, their mutual relationship and the as...

journal_title：Pharmacoepidemiology and drug safety

authors： van Bruggen R,Gorter K,Stolk RP,Zuithoff P,Klungel OH,Rutten GE

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To study patterns of antiepileptic drugs (AED) prescribing, particularly valproate, during pregnancy over a 10-year period in the UK, Italy, and France. METHODS:Data on pregnancies conceived after 1 January 2007 with outcomes before 31 December 2016 were extracted from four European electronic health care data...

journal_title：Pharmacoepidemiology and drug safety

authors： Hurault-Delarue C,Morris JK,Charlton R,Gini R,Loane M,Pierini A,Puccini A,Neville A,Snowball J,Damase-Michel C,EUROmediSAFE consortium.

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:Fear of discontinuing concomitant anti-epileptic drugs (AEDs) may lead to potentially unnecessary and perhaps unsafe polypharmacy. The effect of withdrawing concomitant AEDs on epilepsy control was therefore studied in long-term users of levetiracetam. METHODS:The EULEV cohort followed patients initiating leve...

journal_title：Pharmacoepidemiology and drug safety

authors： Droz-Perroteau C,Marchal C,Dureau-Pournin C,Lassalle R,Jové J,Robinson P,Lavernhe G,Vespignani H,Moore N,Fourrier-Réglat A,Eulev Study Group.

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:Confounding, a concern in nonexperimental research using administrative claims, is nearly ubiquitous in claims-based pharmacoepidemiology studies. A fixed-length look-back window for assessing comorbidity from claims is common, but it may be advantageous to use all historical claims. We assessed how the strengt...

journal_title：Pharmacoepidemiology and drug safety

authors： Gilbertson DT,Bradbury BD,Wetmore JB,Weinhandl ED,Monda KL,Liu J,Brookhart MA,Gustafson SK,Roberts T,Collins AJ,Rothman KJ

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:As covariates are not always adequately balanced after propensity score matching and double- adjustment can be used to remove residual confounding, we compared the performance of several double-robust estimators in different scenarios. METHODS:We conducted a series of Monte Carlo simulations on virtual obser...

journal_title：Pharmacoepidemiology and drug safety

authors： Nguyen TL,Collins GS,Spence J,Devereaux PJ,Daurès JP,Landais P,Le Manach Y

更新日期：2017-12-01 00:00:00

abstract：:Intravenous immunoglobulins (i.v.IG) are increasingly used in various clinical situations for which they have been considered to be safe and effective. However, since 1987, some cases of renal toxicity have been reported. Forty-nine cases of acute renal failure have been notified to the French Regional Pharmacovigilan...

journal_title：Pharmacoepidemiology and drug safety

authors： Gras V,Andréjak M,Decocq G

更新日期：1999-04-01 00:00:00

abstract：:Analysing duration of treatment episodes has become a standard task in many pharmacoepidemiological studies. However, such analyses are often carried out in a rather simplistic manner and more subtle issues are often ignored. In this paper, methods of analysing duration treatment episodes beyond simple analyses allowi...

journal_title：Pharmacoepidemiology and drug safety

authors： Gichangi A,Andersen M,Kragstrup J,Vach W

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The Epidemiologic Registry of Cystic Fibrosis (ERCF) was a multicentre, longitudinal follow-up project of cystic fibrosis patients enrolled at some 200 centres in nine European countries between 1994 and 1999. PURPOSE:We aimed to assess and improve the quality of a subset of data from the ERCF relating to s...

journal_title：Pharmacoepidemiology and drug safety

authors： Strobl J,Enzer I,Bagust A,Haycox A,Smyth R,Ashby D,Walley T

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:Use of albumin (indications and quantities involved) has not been assessed in France since major changes occurred after the publication of Cochrane group meta-analysis. The objectives of this study were to measure the repartition of albumin indications in three French university hospitals in 2004 and to assess ...

journal_title：Pharmacoepidemiology and drug safety

authors： Pradel V,Tardieu S,Micallef J,Signoret A,Villano P,Gauthier L,Vanelle P,Blin O,Albumin Study Group.

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To determine the prevalence of purchase of prescribed antihypertensive and/or serum lipid-reducing pharmaceutical preparations among different age groups, from the age of 45, in the Swedish population. Further, to calculate the percentage of the population, from the age of 60, who purchased these pharmaceutical...

journal_title：Pharmacoepidemiology and drug safety

authors： Silwer L,Lundborg CS,Petzold M

更新日期：2008-01-01 00:00:00

abstract：AIM:To determine the appropriate size of risk windows in both exposed and unexposed sub-cohorts. METHOD:Data was taken from a previous study of upper gastrointestinal haemorrhage and perforation. The length of each prescription for NSAIDs was estimated. The risk was calculated for the duration of a prescription plus i...

journal_title：Pharmacoepidemiology and drug safety

authors： McMahon AD,Evans JM,McGilchrist MM,McDevitt DG,MacDonald TM

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:To evaluate whether the risk of coronary heart disease (CHD) differs among adult diabetic patients treated with thiazolidinediones (TZDs) and similar patients treated with combined oral metformin and sulfonylurea (M + S) therapy. METHODS:We conducted a retrospective cohort study involving 25 140 diabetic patie...

journal_title：Pharmacoepidemiology and drug safety

authors： Johannes CB,Koro CE,Quinn SG,Cutone JA,Seeger JD

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:The objective of this study was to evaluate the validity and completeness of the General Practice Research Database (GPRD) as a tool for research into inflammatory bowel disease epidemiology. METHODS:Patients diagnosed with inflammatory bowel disease were identified from GPRD. Mailed surveys were sent to the g...

journal_title：Pharmacoepidemiology and drug safety

authors： Lewis JD,Brensinger C,Bilker WB,Strom BL

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:To estimate the prevalence of use of prescription drugs with a potential for fetal harm among pregnant women in the United States. METHODS:A retrospective study was conducted using the automated databases of eight health maintenance organizations involved in the HMO Research Network Center for Education and Re...

journal_title：Pharmacoepidemiology and drug safety

authors： Andrade SE,Raebel MA,Morse AN,Davis RL,Chan KA,Finkelstein JA,Fortman KK,McPhillips H,Roblin D,Smith DH,Yood MU,Platt R,H Gurwitz J

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To evaluate the outcomes of patients participating in a program of integrated care for osteoporosis in terms of medication supply, fracture incidence and expenses. METHODS:Outcomes were assessed from secondary data provided by the AOK PLUS health insurance for 2455 participants of the program and the same numb...

journal_title：Pharmacoepidemiology and drug safety

authors： Goltz L,Degenhardt G,Maywald U,Kirch W,Schindler C

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:To describe a bias that can occur in the analysis of data from certain randomized trials. METHODS AND RESULTS:Although randomized trials are effective at preventing confounding, a potentially strong confounding can arise in certain therapeutic drug trials in which follow-up is extended in an open-label phase t...

journal_title：Pharmacoepidemiology and drug safety

authors： Rothman KJ

更新日期：2004-05-01 00:00:00

abstract：AIMS:To evaluate the pattern of prescribing of angiotensin-converting enzyme (ACE) inhibitors in general practice, related to the primary clinical diagnosis and concomitant medication. DESIGN:A descriptive survey of general practitioners' prescribing habits, presumptive diagnosis and patient demography over a period o...

journal_title：Pharmacoepidemiology and drug safety

authors： Connolly JP,Silke B,McGavock H,Wilson-Davies K

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:To investigate a possible increased risk of esophageal obstruction among users of loratadine and pseudoephedrine (Claritin-D 24-Hour [C-D 24], the original, round, extended-release formulation) compared to two other tablet formulations of loratadine. METHODS:Pharmacy data of 12 managed care plans were screened...

journal_title：Pharmacoepidemiology and drug safety

authors： Manda B,Drinkard CR,Shatin D,Graham DJ

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:Determination of the incidence rate of diabetic ketoacidosis (DKA) in type 2 diabetes mellitus (T2DM) is urgent, in response to the safety issue with use of the glucose lowering drugs, sodium-glucose cotransporter-2 inhibitors, and DKA. METHODS:We extracted data of adult patients with T2DM from a medical claim...

journal_title：Pharmacoepidemiology and drug safety

authors： Takeuchi M,Kawamura T,Sato I,Kawakami K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:European Surveillance of Congenital Anomalies (EUROCAT) is a network of population-based congenital anomaly registries in Europe surveying more than 1 million births per year, or 25% of the births in the European Union. This paper describes the potential of the EUROCAT collaboration for pharmacoepidemiology ...

journal_title：Pharmacoepidemiology and drug safety

authors： Meijer WM,Cornel MC,Dolk H,de Walle HE,Armstrong NC,de Jong-van den Berg LT,EUROCAT Working Group.

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Recent case series have associated the synthetic opioid, methadone, with QT prolongation and torsades de pointes (TdP) ventricular arrhythmia. STUDY OBJECTIVE:To review and analyze adverse events (QT prolongation and TdP) reported to the Food and Drug Administration (FDA) to determine the patient characteri...

journal_title：Pharmacoepidemiology and drug safety

authors： Pearson EC,Woosley RL

更新日期：2005-11-01 00:00:00

abstract：:Meloxicam (Mobic((R))) was introduced in the UK in 1996 as a nonsteroidal anti-inflammatory drug (NSAID). To help evaluate the postmarketing experience with meloxicam in the UK, we used the General Practitioners Research Database (GPRD) to characterize the baseline risk of an upper gastrointestinal (GI) event among ne...

journal_title：Pharmacoepidemiology and drug safety

authors： Lanes SF,Rodrígeuz LA,Hwangg E

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:The role of administrative databases for research on drug safety during pregnancy can be limited by their inaccurate assessment of the timing of exposure, as the gestational age at birth is typically unavailable. Therefore, we sought to develop and validate algorithms to estimate the gestational age at birth us...

journal_title：Pharmacoepidemiology and drug safety

authors： Margulis AV,Setoguchi S,Mittleman MA,Glynn RJ,Dormuth CR,Hernández-Díaz S

更新日期：2013-01-01 00:00:00