Abstract:
:HgCl2 and mersalyl increased and later decreased both the spontaneous and evoked transmitter liberation at the frog neuromuscular junction. Lower concentration of HgCl2 exhibited only an inhibitory effect on transmitter release. These mercurials inhibited calcium transport of mitochondria and synaptosomal vesicles. Lower concentrations of HgCl2 showed a stimulatory effect on mitochondrial calcium uptake. It is suggested that the effect of mercurials on transmitter release is mediated via changes of the intracellular calcium ion concentration.
journal_name
Eur J Pharmacoljournal_title
European journal of pharmacologyauthors
Binah O,Meiri U,Rahamimoff Hdoi
10.1016/0014-2999(78)90438-7subject
Has Abstractpub_date
1978-10-15 00:00:00pages
453-7issue
4eissn
0014-2999issn
1879-0712pii
0014-2999(78)90438-7journal_volume
51pub_type
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