Hypertrophic Cardiomyopathy in Patients with Atrial Fibrillation: Prevalence and Associated Stroke Risks in a Nationwide Cohort Study.

abstract：:Pregnancy and delivery have measurable effects on haemostatic and immunological changes. Degradation of fibrinogen induces significant structural and conformational modulation and leads to the progressive loss of antigenic sites present on the parent molecule but also exposes some new sites. These neoantigens may be r...

journal_title：Thrombosis and haemostasis

authors： Kondera-Anasz Z

更新日期：1998-05-01 00:00:00

abstract：:Thrombus formation is recognized pathologically in the affected arteries and is supposed to play a major role in the pathogenesis of Takayasu's arteritis; however, hemostatic conditions in this disorder have not been elucidated fully. We determined plasma levels of molecular markers for platelet activity (platelet fac...

journal_title：Thrombosis and haemostasis

authors： Akazawa H,Ikeda U,Yamamoto K,Kuroda T,Shimada K

更新日期：1996-05-01 00:00:00

abstract：:A pulmonary embolism model in hamsters was used for the quantitative evaluation of the thrombolytic and pharmacokinetic properties of variants of tissue-type plasminogen activator (t-PA). A 25 microliters 125I-fibrin labeled human plasma clot was made in vitro and injected into the jugular vein of heparinized hamsters...

journal_title：Thrombosis and haemostasis

authors： Collen D,Lijnen HR,Vanlinthout I,Kieckens L,Nelles L,Stassen JM

更新日期：1991-02-12 00:00:00

abstract：:Transient procoagulant states resulting in failure of recanalization or rethrombosis of the reperfused artery during thrombolytic therapy might be due to an inhibitory effect of plasmin on the anticoagulant properties of protein C. We therefore studied the effect of plasmin on protein C (PC) and activated protein C (A...

journal_title：Thrombosis and haemostasis

authors： Váradi K,Philapitsch A,Santa T,Schwarz HP

更新日期：1994-05-01 00:00:00

abstract：:The effects on the haemostatic mechanism of oestrogen therapy, given to prevent bone loss in post-menopausal women, have been investigated. Oestriol succinate was given orally to 10 women at a level of 2 mg/day for 1 month and for a further 3 months with incremental increase of 2 mg each month. 6 of the 10 women were ...

journal_title：Thrombosis and haemostasis

authors： Davies T,Fieldhouse G,McNicol GP

更新日期：1976-04-30 00:00:00

abstract：:The influence of ionic and non-ionic contrast media (CM) on platelet and leukocyte activation and platelet-leukocyte crosstalk was investigated in hirudinized whole blood. The blood was incubated with and without the ionic CM ioxaglate and the nonionic CM iodixanol at 37 degrees C for 5 min, without or with stirring. ...

journal_title：Thrombosis and haemostasis

authors： Ji Q,Ghaly M,Hjemdahl P,Tornvall P,Li N

更新日期：2005-05-01 00:00:00

abstract：:Accumulation of the newly formed 14C-cyclic adenosine 3',5'-monophosphate (cyclic AMP) was found in the P1 (1.0) fraction, i.e. a platelet plasma membrane fraction which was obtained from 14C-adenine-labeled platelets. On the other hand, total cyclic AMP as determined simultaneously was located mainly in the platelet ...

journal_title：Thrombosis and haemostasis

authors： Hashimoto S

更新日期：1983-02-28 00:00:00

abstract：:Transplant-associated thrombotic microangiopathy (TA-TMA) is a life-threatening complication of allogeneic hematopoietic cell transplantation (HCT). We hypothesized that pretransplant genetic susceptibility is evident in adult TA-TMA and further investigated the association of TMA-associated variants with clinical out...

journal_title：Thrombosis and haemostasis

authors： Gavriilaki E,Touloumenidou T,Sakellari I,Batsis I,Mallouri D,Psomopoulos F,Tsagiopoulou M,Koutra M,Yannaki E,Papalexandri A,Taylor P,Nikolousis E,Stamouli M,Holbro A,Baltadakis I,Liga M,Spyridonidis A,Tsirigotis P,Cha

更新日期：2020-04-01 00:00:00

abstract：:Tissue factor (TF) plays a pivotal role in thrombus formation and atherogenesis in acute coronary syndrome. Tissue factor pathway inhibitor (TFPI) is a specific physiological inhibitor of TF/FVIIa complex that regulates TF-induced coagulation. Adiponectin (Adp) is an adipocyte-specific adipocytokine with anti-atheroge...

journal_title：Thrombosis and haemostasis

authors： Chen YJ,Zhang LQ,Wang GP,Zeng H,Lü B,Shen XL,Jiang ZP,Chen FP

更新日期：2008-08-01 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine with chemokine-like functions. MIF is a critical mediator of the host immune and inflammatory response. Dysregulated MIF expression has been demonstrated to contribute to various acute and chronic inflammatory conditions as well as cancer developme...

journal_title：Thrombosis and haemostasis

authors： Asare Y,Schmitt M,Bernhagen J

更新日期：2013-03-01 00:00:00

abstract：:A high throughput 384-well plate assay of blood function in 60 microl reactions with the fluorogenic thrombin substrate, boc-VPR-MCA, allowed for real-time monitoring of coagulation under a diverse set of reaction conditions. Using recalcified, citrated whole blood diluted 3-fold with corn trypsin inhibitor (to block ...

journal_title：Thrombosis and haemostasis

authors： Lo K,Diamond SL

更新日期：2004-10-01 00:00:00

abstract：:There is no patient-reported medication adherence measure that has been validated in Singapore. This study aimed to validate the 8-item Morisky Medication Adherence Scale (MMAS) in patients taking warfarin in Singapore. A cross-sectional survey was conducted in a convenience sample of 151 patients taking warfarin at a...

journal_title：Thrombosis and haemostasis

authors： Wang Y,Kong MC,Ko Y

更新日期：2012-10-01 00:00:00

abstract：:EPCR is a type I transmembrane protein, highly expressed on the endothelium of large vessels, that binds protein C and augments its activation. In this study, a 23bp insertion in the EPCR gene was found in 4/198 survivors of myocardial infarction and 3/194 patients with deep vein thrombosis. The EPCR gene with the ins...

journal_title：Thrombosis and haemostasis

authors： Biguzzi E,Merati G,Liaw PC,Bucciarelli P,Oganesyan N,Qu D,Gu JM,Fetiveau R,Esmon CT,Mannucci PM,Faioni EM

更新日期：2001-10-01 00:00:00

abstract：:We tested different types of clot for their ability to provoke procoagulant activity in platelets: normal clots from platelet poor plasma (des AABB- or fibrin II clots), similar clots in which the adsorbed thrombin has been inhibited by hirudin, and clots obtained by the action of two snake venom enzymes that release ...

journal_title：Thrombosis and haemostasis

authors： Kumar R,Béguin S,Hemker HC

更新日期：1995-09-01 00:00:00

abstract：:We studied the recovery pattern of platelet malondialdehyde (MDA) formation after a single intake of various doses of aspirin (ASA). In normal subjects, there were striking differences in the recovery pattern between large doses (1,000 or 500 mg) and small doses (100 or 50 mg) of oral ASA. The 2 day lag phase was pres...

journal_title：Thrombosis and haemostasis

authors： Takayama H,Okuma M,Uchino H

更新日期：1982-08-24 00:00:00

abstract：:This study explores the effects on some hematological parameters of a low-dose aspirin regimen (50 mg/day) versus a conventional aspirin treatment with reported antithrombotic efficacy (324 mg/day), in patients with acute myocardial infarction. Fifteen patients were randomized into 3 equal groups receiving 50 mg or 32...

journal_title：Thrombosis and haemostasis

authors： De Caterina R,Giannessi D,Boem A,Bernini W,Battaglia D,Michelassi C,Dell'Amico F,L'Abbate A,Patrignani P,Patrono C

更新日期：1985-08-30 00:00:00

abstract：:It was our aim to assess whether factor V Leiden (FVL) and G20210A prothrombin (FII) mutation are associated with the presence of residual vein obstruction (RVO) after a standard course of anticoagulation for a first episode of idiopathic proximal deep-vein thrombosis (DVT) of the lower limbs, with or without symptoma...

journal_title：Thrombosis and haemostasis

authors： Cosmi B,Legnani C,Pengo V,Ghirarduzzi A,Testa S,Poli D,Prisco D,Tripodi A,Palareti G,PROLONG Investigators (on behalf of FCSA, Italian Federation of Anticoagulation Clinics).

更新日期：2013-03-01 00:00:00

abstract：:In the past decade understanding of the role of the Rho GTPases RhoA, Rac1 and Cdc42 has been developed from regulatory proteins that regulate specific actin cytoskeletal structures - stress fibers, lamellipodia and filopodia - to complex integrators of cytoskeletal structures that can exert multiple functions dependi...

journal_title：Thrombosis and haemostasis

authors： Beckers CM,van Hinsbergh VW,van Nieuw Amerongen GP

更新日期：2010-01-01 00:00:00

abstract：:Thromboembolic complications have been attributed to the use of radiographic contrast media (CM) during interventional procedures for arterial revascularization. However, due to the low frequency of adverse events, comparisons between different CM have been difficult to perform, although it has been suggested that ion...

journal_title：Thrombosis and haemostasis

authors： Markou CP,Chronos NA,Hanson SR

更新日期：2001-03-01 00:00:00

abstract：:The salivary complex of the leech Haementeria depressa produces potent anticoagulant components. Among them, a protein named lefaxin inhibits factor Xa (FXa). Lefaxin was purified to homogeneity from dissected salivary complexes by gel filtration in Sephadex G-150 followed by two ion exchange chromatography steps in M...

journal_title：Thrombosis and haemostasis

authors： Faria F,Kelen EM,Sampaio CA,Bon C,Duval N,Chudzinski-Tavassi AM

更新日期：1999-11-01 00:00:00

abstract：:Desmopressin acetate administration markedly stimulates release of tissue plasminogen activator (t-PA) from vascular endothelial cells. The mechanism for this effect is unknown. Because infusion of epinephrine has been shown to increase t-PA levels, we examined the role of endogenous catecholamine mediation of t-PA re...

journal_title：Thrombosis and haemostasis

authors： Grant MB,Guay C,Lottenberg R

更新日期：1988-04-08 00:00:00

abstract：:Bleeding time and platelet function tests were performed on 31 patients with progressive chronic renal failure (CRF) due to non-immunological (urological) causes, and compared with 22 healthy controls. Patients were classified as mild (plasma creatinine less than 300 mumol/l), moderate (300-600 mumol/l) or severe rena...

journal_title：Thrombosis and haemostasis

authors： Gordge MP,Faint RW,Rylance PB,Neild GH

更新日期：1988-08-30 00:00:00

abstract：:Dilated cardiomyopathy is associated with thromboembolic complications, which correlate poorly, however, with a visible left ventricular thrombus. Therefore, this study was performed to assess whether an abnormality of platelet function in vivo can be detected in patients with dilated cardiomyopathy. Platelet survival...

journal_title：Thrombosis and haemostasis

authors： Weidinger F,Glogar D,Sochor H,Sinzinger H

更新日期：1991-10-01 00:00:00

abstract：:The inhibitory capacity of antithrombin III (AT III) was measured by a quantitative method independent of the velocity of inhibition. When AT III was in excess of thrombin in plasma or in purified system the capacity of inhibitor decreased quantitatively in proportion to the amount of thrombin neutralized. Heparin pre...

journal_title：Thrombosis and haemostasis

authors： Marciniak E

更新日期：1977-08-31 00:00:00

abstract：:The etiology and pathophysiology of cerebral sinus venous thrombosis (CSVT) in the paediatric population is still poorly understood, and the role of thrombophilic risk factors remains to be elucidated. In our multi-center case-controlled study we studied 46 patients with CSVT diagnosed from April 1996 to December 2003...

journal_title：Thrombosis and haemostasis

authors： Kenet G,Waldman D,Lubetsky A,Kornbrut N,Khalil A,Koren A,Wolach B,Fattal A,Kapelushnik J,Tamary H,Yacobovitch J,Raveh E,Revel-Vilk S,Toren A,Brenner B

更新日期：2004-10-01 00:00:00

abstract：:The mechanisms or host factors involved in septic thrombus or vegetation formation in Staphylococcus aureus-induced infective endocarditis (IE) are unclear. Using an experimental endocarditis rat model, here we demonstrated that S. aureus HG001-induced vegetation was composed of bacterial floes encased in aggregated p...

journal_title：Thrombosis and haemostasis

authors： Hsu CC,Hsu RB,Ohniwa RL,Chen JW,Yuan CT,Chia JS,Jung CJ

更新日期：2019-05-01 00:00:00

abstract：:Patients with diabetes display increased platelet activation. Recent data show a markedly increased risk for cardiovascular events already in pre-diabetic individuals with impaired glucose tolerance (IGT). We investigated whether IGT is associated with platelet activation. Blood samples were collected from young lean ...

journal_title：Thrombosis and haemostasis

authors： Schäfer A,Widder J,Eigenthaler M,Bischoff H,Ertl G,Bauersachs J

更新日期：2004-07-01 00:00:00

abstract：:To study the predictive value of coagulation markers concerning clinical outcome, prothrombin fragment F1.2 (F1.2), fibrin monomer antigen (FM), D-Dimer (DD), and fibrinogen were measured in plasma samples drawn 2 and 7 days after acute myocardial infarction (AMI) in 314 consecutive patients randomized in a clinical t...

journal_title：Thrombosis and haemostasis

authors： Dempfle CE,Kontny F,Abildgaard U

更新日期：1999-05-01 00:00:00

abstract：:The urinary excretion rate of antithrombin III related antigen (AT III RA) was examined in cerebral stroke. The excretion rate of AT III RA in cerebral hemorrhage (CH) was 12.33 +/- 1.61 X 10(-4) ml/min. The patients with CH were further classified into two groups: in group CH-I, whose consciousness state was stupor o...

journal_title：Thrombosis and haemostasis

authors： Matsuo T,Shinomiya K,Okuno S,Matsuo C,Matsuo O

更新日期：1984-12-29 00:00:00

abstract：:Platelet activation and aggregation are critical in the pathogenesis of acute ischemic cerebrovascular diseases. The aim of our study was to characterize platelet function in patients with acute ischemic stroke or transient ischemic attack (TIA), and to evaluate the effect of platelet activation on clinical outcome. O...

journal_title：Thrombosis and haemostasis

authors： Fateh-Moghadam S,Htun P,Tomandl B,Sander D,Stellos K,Geisler T,Langer H,Walton K,Handschu R,Garlichs C,Daniel WG,Gawaz M

更新日期：2007-06-01 00:00:00