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Propensity-matched comparison of cryoballoon and radiofrequency ablation for atrial fibrillation in elderly patients.

Abstract：

BACKGROUND:Pulmonary vein isolation (PVI) with a cryoballoon (CB) is an effective treatment for atrial fibrillation (AF). The efficacy of CB PVI for elderly patients with AF remains unclear. OBJECTIVE:We aimed to analyze the clinical outcomes of CB ablation compared with radiofrequency (RF) ablation in elderly patients with AF. METHODS:This was a single-center retrospective study of 305 patients older than 75 years with paroxysmal and persistent AF who underwent PVI between January 2012 and August 2017. Patients were matched according to propensity scores in a logistic regression model. The end point of this study was AF/atrial tachycardia recurrence at 12-month follow-up. RESULTS:In total, 198 patients (99 matched pairs) were analyzed. The ratio of paroxysmal AF was 83%, and the mean age was 78 ± 2 years. The mean procedure time was significantly lower in the CB group (134 ± 62 minutes vs 190 ± 51 minutes; P < .001). There was no significant difference between the groups in terms of success rate at 12 months after the procedure (CB 80.5% vs RF 79.4%; P = .72) or incidence of complications (CB 12% vs RF 16%; P = .80). Kaplan-Meier estimates revealed no significant difference between clinical outcomes after PVI with a CB or RF for elderly patients with non-pulmonary vein foci that were all successfully ablated (CB 68.8% vs RF 68.4% at 12 months; P = .835). CONCLUSION:The efficacy of PVI with a CB might be comparable to that of PVI with RF in AF patients older than 75 years and involve a shorter procedure time.

journal_name

Heart Rhythm

journal_title

Heart rhythm

authors

Ikenouchi T,Nitta J,Nitta G,Kato S,Iwasaki T,Murata K,Junji M,Hirao T,Kanoh M,Takamiya T,Kato N,Inamura Y,Negi K,Sato A,Yamato T,Matsumura Y,Takahashi Y,Goya M,Hirao K

doi

10.1016/j.hrthm.2018.12.019

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

838-845

issue

6

eissn

1547-5271

issn

1556-3871

pii

S1547-5271(18)31285-2

journal_volume

16

pub_type

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