Abstract:
BACKGROUND:Standard electroanatomic mapping systems use a single catheter to perform left ventricular substrate mapping. A new mapping system uses a 64-electrode mini-basket catheter to perform rapid automated acquisition of chamber geometry, voltage, and activation. OBJECTIVE:The aim of this study was to compare the accuracy of electroanatomic mapping using the basket catheter with that of mapping using a standard linear catheter in a swine model of chronic myocardial infarction. METHODS:Ten swine underwent left anterior descending coronary artery occlusion to create an anteroseptal myocardial infarction. Animals underwent delayed-enhancement magnetic resonance imaging (MRI) and then detailed left ventricular voltage mapping with both the basket and the linear catheter. Map characteristics and scar area were compared between the basket catheter, linear catheter, and MRI. Induced ventricular tachycardia (VT) was mapped with the basket catheter. RESULTS:More points were acquired with the basket catheter than with the standard catheter (8762 ± 3164 vs 1712 ± 551; P < .001). The fifth percentile of normal bipolar voltage distribution with the basket catheter was 1.54 mV. Using a bipolar voltage cutoff of 1.5 mV, the total infarct areas measured using the basket catheter, linear catheter, and MRI were similar (17.8 cm(2) vs 20.9 cm(2) vs 17.5 cm(2); P = .69); however, the correlation between MRI and catheter scar area measurement was best for the basket catheter (basket vs linear: r = .76 vs r = .71). In 3 animals, sustained poorly tolerated VT was initiated and the circuit mapped successfully with the basket catheter in <5 minutes. CONCLUSION:Rapid substrate and activation mapping using a 64-electrode mini-basket catheter allows detailed voltage and activation mapping in postinfarction cardiomyopathy. This system may be useful for substrate and VT mapping in human postinfarction cardiomyopathy.
journal_name
Heart Rhythmjournal_title
Heart rhythmauthors
Tanaka Y,Genet M,Chuan Lee L,Martin AJ,Sievers R,Gerstenfeld EPdoi
10.1016/j.hrthm.2014.08.036subject
Has Abstractpub_date
2015-01-01 00:00:00pages
144-54issue
1eissn
1547-5271issn
1556-3871pii
S1547-5271(14)00925-4journal_volume
12pub_type
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