Abstract:
PURPOSE:To investigate the correlation between retinal vessel oxygen saturation and mixed venous oxygen saturation (SvO2-mixed ) and cardiac output (CO). METHODS:Retinal arterial (SaO2-retinal ) and venous (SvO2-retinal ) oxygen saturation were measured non-invasively with dual-wavelength retinal oximetry in subjects receiving invasive measurements of SvO2-mixed and CO through right heart catheterization. Correlations were analysed using Spearman's rank correlation coefficients and linear regression models. RESULTS:Fourteen patients (median age 62.7 years, range: 21-77) were included in the analysis. When adjusted for age, SvO2-retinal showed a positive correlation with SvO2-mixed (β = 0.80, p = 0.003). Retinal arteriovenous oxygen saturation difference was significantly correlated with the inverse of CO (Spearman's ρ = 0.59, p = 0.026). CONCLUSION:This pilot study provides proof of concept for the use of retinal oximetry as a non-invasive tool to assess systemic cardiovascular function.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Van Keer K,Van Keer J,Barbosa Breda J,Nassiri V,Van Cleemput J,Abegão Pinto L,Stalmans I,Vandewalle Edoi
10.1111/aos.13890subject
Has Abstractpub_date
2019-03-01 00:00:00pages
e308-e312issue
2eissn
1755-375Xissn
1755-3768journal_volume
97pub_type
杂志文章abstract:PURPOSE:To investigate whether introduction of item-response theory (IRT) analysis, in parallel to the 'traditional' statistical analysis methods available for performance evaluation of multiple T/F items as used in the European Board of Ophthalmology Diploma (EBOD) examination, has proved beneficial, and secondly, to ...
journal_title:Acta ophthalmologica
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abstract:PURPOSE:To evaluate the EyeSi(™) simulator in regard to assessing competence in cataract surgery. The primary objective was to explore all simulator metrics to establish a proficiency-based test with solid evidence. The secondary objective was to evaluate whether the skill assessment was specific to cataract surgery. ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12691
更新日期:2015-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
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更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To study the genetic aetiology of retinal dystrophies (RD) in Finnish patients. METHODS:A targeted next-generation sequencing (NGS) panel of 105 retinal dystrophy genes was used in a cohort of 55 RD patients. RESULTS:The overall diagnostic yield was 60% demonstrating the power of this approach. Interestingly,...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To determine associations between physical activity (PA) and myopia in Danish school children and investigate the prevalence of myopia. METHODS:This is a prospective study with longitudinal data on PA in a Danish child cohort. Physical activity (PA) was measured objectively by repeated ActiGraph accelerometer ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13513
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To investigate the amount of systemic oxidative stress-related DNA damage and serum total antioxidant status of patients with normal-tension glaucoma compared with healthy controls. METHODS:Forty-three patients with normal-tension glaucoma selected from 60 consecutive newly diagnosed patients with primary open...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01997.x
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abstract:PURPOSE:Monthly dosing with ranibizumab (RBZ) is needed to achieve maximal visual gains in patients with neovascular ('wet') age-related macular degeneration (wAMD). In Sweden, dosing is performed as needed (RBZ PRN), resulting in suboptimal efficacy. Intravitreal aflibercept (IVT-AFL) every 2 months after three initia...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12964
更新日期:2016-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13209
更新日期:2017-02-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12744
更新日期:2015-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01683.x
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:Contact lenses have direct contact with the corneal surface and can induce sight-threatening infection of the cornea known as Acanthamoeba keratitis. The objective of this study was to evaluate the dysprosium-based nanoparticles (Dy-based NPs), namely Fe3 O4 -PEG-Dy2 O3 nanocomposites and Dy(OH)3 nanorods, as a...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14541
更新日期:2020-07-23 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12238
更新日期:2014-06-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type:
doi:10.1111/aos.13223
更新日期:2017-02-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13899
更新日期:2019-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13003
更新日期:2016-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
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journal_title:Acta ophthalmologica
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doi:10.1111/j.1755-3768.2009.01752.x
更新日期:2011-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01880.x
更新日期:2012-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14708
更新日期:2021-01-09 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02448.x
更新日期:2012-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01799.x
更新日期:2011-05-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14350
更新日期:2020-01-24 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13397
更新日期:2017-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14713
更新日期:2021-01-08 00:00:00
abstract:BACKGROUND/AIMS:The mitotic count of uveal melanomas correlates with the risk of metastatic death, but with haematoxylin and eosin (H&E)-stained sections, it can be difficult to identify mitotic figures (MF) reliably. We investigated whether this measurement could be enhanced by immunohistochemistry, using the mitosis-...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01769.x
更新日期:2011-03-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13502
更新日期:2018-03-01 00:00:00