Retinal oxygen saturation as a non-invasive estimate for mixed venous oxygen saturation and cardiac output.


PURPOSE:To investigate the correlation between retinal vessel oxygen saturation and mixed venous oxygen saturation (SvO2-mixed ) and cardiac output (CO). METHODS:Retinal arterial (SaO2-retinal ) and venous (SvO2-retinal ) oxygen saturation were measured non-invasively with dual-wavelength retinal oximetry in subjects receiving invasive measurements of SvO2-mixed and CO through right heart catheterization. Correlations were analysed using Spearman's rank correlation coefficients and linear regression models. RESULTS:Fourteen patients (median age 62.7 years, range: 21-77) were included in the analysis. When adjusted for age, SvO2-retinal showed a positive correlation with SvO2-mixed (β = 0.80, p = 0.003). Retinal arteriovenous oxygen saturation difference was significantly correlated with the inverse of CO (Spearman's ρ = 0.59, p = 0.026). CONCLUSION:This pilot study provides proof of concept for the use of retinal oximetry as a non-invasive tool to assess systemic cardiovascular function.


Acta Ophthalmol


Acta ophthalmologica


Van Keer K,Van Keer J,Barbosa Breda J,Nassiri V,Van Cleemput J,Abegão Pinto L,Stalmans I,Vandewalle E




Has Abstract


2019-03-01 00:00:00












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    pub_type: 杂志文章


    authors: Jongman HP,Marinkovic M,Notting I,Koetsier L,Swart W,Schalij-Delfos NE,Bleeker J,Jager MJ,Luyten GP

    更新日期:2016-05-01 00:00:00

  • Recommendations for ophthalmologic practice during the easing of COVID-19 control measures.

    abstract::In the context of the COVID-19 pandemic, this paper provides recommendations for medical eye care during the easing of control measures after lockdown. The guidelines presented are based on a literature review and consensus among all Spanish Ophthalmology Societies regarding protection measures recommended for the oph...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,评审


    authors: Gegúndez-Fernández JA,Llovet-Osuna F,Fernández-Vigo JI,Mendicute Del Barrio J,Pablo-Júlvez L,Muñoz-Negrete FJ,Zarranz-Ventura J,Durán de la Colina J,de Rojas Silva V,Jiménez-Alfaro I,Calonge-Cano M,Galindo-Ferreiro A,Castillo-Góm

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    authors: Lee HS,Park SW,Heo H

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    abstract:PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

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    authors: Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

    更新日期:2016-11-01 00:00:00

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    pub_type: 杂志文章


    authors: Murakami Y,Ikeda Y,Nakatake S,Fujiwara K,Tachibana T,Yoshida N,Notomi S,Hisatomi T,Yoshida S,Ishibashi T,Sonoda KH

    更新日期:2018-03-01 00:00:00

  • Optical performance after bilateral implantation of apodized aspheric diffractive multifocal intraocular lenses with +3.00-D addition power.

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    authors: Peng C,Zhao J,Ma L,Qu B,Sun Q,Zhang J

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  • Increased anterior chamber penetration of topical levofloxacin 0.5% after pulsed dosing in cataract patients.

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    pub_type: 杂志文章,随机对照试验


    authors: Sundelin K,Seal D,Gardner S,Ropo A,Geldsetzer K,Lokkila J,Stenevi U

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  • Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study.

    abstract:PURPOSE:To investigate changes in retinal metabolism, function, structure and morphology in relation to initiation of insulin pump therapy (continuous subcutaneous insulin infusion, CSII). METHODS:Visual acuity, retinopathy level, dark adaptation kinetics, retinal and subfoveal choroidal thickness, macular perfusion v...

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    pub_type: 杂志文章,随机对照试验


    authors: Klefter ON,Hommel E,Munch IC,Nørgaard K,Madsbad S,Larsen M

    更新日期:2016-09-01 00:00:00

  • Vascular endothelial growth factor plasma levels before and after treatment of neovascular age-related macular degeneration with bevacizumab or ranibizumab.

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    pub_type: 杂志文章


    authors: Carneiro AM,Costa R,Falcão MS,Barthelmes D,Mendonça LS,Fonseca SL,Gonçalves R,Gonçalves C,Falcão-Reis FM,Soares R

    更新日期:2012-02-01 00:00:00

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    pub_type: 杂志文章,多中心研究


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    更新日期:2019-08-01 00:00:00

  • A study of stromal riboflavin absorption in ex vivo porcine corneas using new and existing delivery protocols for corneal cross-linking.

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    authors: Hayes S,Morgan SR,O'Brart DP,O'Brart N,Meek KM

    更新日期:2016-03-01 00:00:00

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    pub_type: 杂志文章,评审


    authors: Ellis-Behnke R,Jonas JB

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    pub_type: 杂志文章


    authors: Martinez A,Proupim N,Sanchez M

    更新日期:2009-11-01 00:00:00

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    authors: van Nispen R,van der Aa H,Timmermans F,Meijer N,Koster N,de Blok J,Keunen J,van Rens G

    更新日期:2019-06-01 00:00:00

  • Optimizing the treatment of rhegmatogenous retinal detachment.

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    pub_type: 历史文章,杂志文章


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    更新日期:2016-03-01 00:00:00

  • Detailed optical coherence tomography angiographic short-term response of type 3 neovascularization to combined treatment with photodynamic therapy and intravitreal bevacizumab.

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    更新日期:2020-06-29 00:00:00

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    更新日期:2020-05-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Mendez-Hernandez C,Rodriguez-Uña I,Gonzalez-de-la Rosa M,Arribas-Pardo P,Garcia-Feijoo J

    更新日期:2016-11-01 00:00:00

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    pub_type: 杂志文章,评审


    authors: Schulze S,Hoerle S,Mennel S,Kroll P

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    pub_type: 杂志文章


    authors: Bonnin P,Pournaras JA,Lazrak Z,Cohen SY,Legargasson JF,Gaudric A,Levy BI,Massin P

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    pub_type: 杂志文章


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    pub_type: 杂志文章,meta分析,评审


    authors: Thvilum M,Brandt F,Brix TH,Hegedüs L

    更新日期:2017-12-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2013-12-01 00:00:00

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    更新日期:2014-05-01 00:00:00

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    更新日期:2020-09-16 00:00:00