Abstract:
PURPOSE:To investigate the correlation between retinal vessel oxygen saturation and mixed venous oxygen saturation (SvO2-mixed ) and cardiac output (CO). METHODS:Retinal arterial (SaO2-retinal ) and venous (SvO2-retinal ) oxygen saturation were measured non-invasively with dual-wavelength retinal oximetry in subjects receiving invasive measurements of SvO2-mixed and CO through right heart catheterization. Correlations were analysed using Spearman's rank correlation coefficients and linear regression models. RESULTS:Fourteen patients (median age 62.7 years, range: 21-77) were included in the analysis. When adjusted for age, SvO2-retinal showed a positive correlation with SvO2-mixed (β = 0.80, p = 0.003). Retinal arteriovenous oxygen saturation difference was significantly correlated with the inverse of CO (Spearman's ρ = 0.59, p = 0.026). CONCLUSION:This pilot study provides proof of concept for the use of retinal oximetry as a non-invasive tool to assess systemic cardiovascular function.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Van Keer K,Van Keer J,Barbosa Breda J,Nassiri V,Van Cleemput J,Abegão Pinto L,Stalmans I,Vandewalle Edoi
10.1111/aos.13890subject
Has Abstractpub_date
2019-03-01 00:00:00pages
e308-e312issue
2eissn
1755-375Xissn
1755-3768journal_volume
97pub_type
杂志文章abstract:PURPOSE:To report the postoperative results after enucleation of using an acrylic orbital implant covered in donor sclera for implantation. METHODS:We retrospectively analysed the charts of patients who were enucleated between 2007 and 2011. Only patients who received an acrylic implant covered with donor sclera were ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12960
更新日期:2016-05-01 00:00:00
abstract::In the context of the COVID-19 pandemic, this paper provides recommendations for medical eye care during the easing of control measures after lockdown. The guidelines presented are based on a literature review and consensus among all Spanish Ophthalmology Societies regarding protection measures recommended for the oph...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.14752
更新日期:2021-01-12 00:00:00
abstract:PURPOSE:To compare various optic nerve head (ONH) parameters and peripapillary retinal nerve fibre layer (pRNFL) thickness between megalopapilla cases and normal control using spectral domain optical coherence tomography (SD-OCT) in children. METHODS:Fifty eyes with megalopapilla and 80 normal control eyes of totally ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12545
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13047
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship bet...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13502
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To determine whether bilateral implantation of an aspheric apodized diffractive multifocal intraocular lens (IOL) with +3.00 diopters (D) results in optical adverse effects compared with an aspheric monofocal IOL. METHODS: In a prospective, randomized study of 204 eyes (102 patients) with bilateral implantati...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1755-3768.2012.02497.x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:This study aimed to investigate the rise in aqueous humour (AH) levels of levofloxacin after a specific perioperative pulsed topical drop regimen. METHODS:Thirty patients undergoing phacoemulsification surgery were administered two preoperative drops of levofloxacin 0.5%, 30 mins apart, and three pulsed drops ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1755-3768.2008.01358.x
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To investigate changes in retinal metabolism, function, structure and morphology in relation to initiation of insulin pump therapy (continuous subcutaneous insulin infusion, CSII). METHODS:Visual acuity, retinopathy level, dark adaptation kinetics, retinal and subfoveal choroidal thickness, macular perfusion v...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aos.13066
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To evaluate the changes of vascular endothelial growth factor (VEGF) plasma levels after intravitreal injections of ranibizumab or bevacizumab in patients with exudative age-related macular degeneration (AMD). METHODS:Forty-three patients with exudative AMD and 19 age- and sex-matched control patients without ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02240.x
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:To investigate whether exposure to antazoline-naphazoline eye drops in the first trimester of pregnancy was associated with an increased risk of malformations in humans. METHODS:All women giving live birth between 1997 and 2011 in Denmark were included in this nationwide cohort study. All women redeeming at le...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/aos.13980
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:To indirectly measure stromal riboflavin penetration using commercially available riboflavin solutions and new and existing epithelium-off, trans-epithelial and iontophoresis-assisted delivery protocols. METHODS:Forty porcine eyes were divided into eight groups. Group 1: Ricrolin applied to the de-epithelialis...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12884
更新日期:2016-03-01 00:00:00
abstract::Working at the nanoscale means to completely rethink how to approach engineering in the body in general and in the eye in particular. In nanomedicine, tissue engineering is the ability to influence an environment either by adding, subtracting or manipulating that environment to allow it to be more conducive for its pu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2010.01982.x
更新日期:2011-03-01 00:00:00
abstract:PURPOSE: This study aimed to compare scanning laser polarimetry measurements of retinal nerve fibre layer (RNFL) thickness in eyes of migraine patients with those in eyes of age-matched, healthy subjects. METHODS: The study was designed as an observational, prospective, cross-sectional study. It included 57 eyes of 57...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01356.x
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To investigate the prevalence of potential age-related eye conditions in elderly who are assisted by home healthcare nurses. The number of referrals to the general practitioner (GP), feasibility of screening and associations between vision loss and health outcomes were also studied. METHODS:Cross-sectional stu...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/aos.13956
更新日期:2019-06-01 00:00:00
abstract::Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...
journal_title:Acta ophthalmologica
pub_type: 历史文章,杂志文章
doi:10.1111/aos.12991
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:To explore the short-term vascular and structural changes of type 3 neovascularization using optical coherence tomography angiography (OCT-A) when treated with a combination of photodynamic therapy (PDT) and intravitreal bevacizumab (IVB), and to evaluate the course of different sequences of the combined therap...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14525
更新日期:2020-06-29 00:00:00
abstract:PURPOSE:To analyse characteristics from the SMR to explore the risk factors for visual acuity (VA) below ≤ 35 letters of the Early Treatment Diabetic Retinopathy Study (ETDRS) due to nAMD during a two-year follow-up. METHODS:This study evaluates 6142 treatment-naïve eyes, with focus on a subgroup of 780 eyes with fina...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14239
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:Galectin-1 regulates endothelial cell function and promotes angiogenesis. We investigated the hypothesis that galectin-1 may be involved in the pathogenesis of proliferative diabetic retinopathy (PDR). METHODS:Vitreous samples from 36 PDR and 20 nondiabetic patients, epiretinal fibrovascular membranes from 13 ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14191
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To report the indications and the outcomes of keratoplasties in children over four decades. METHODS:A retrospective cohort study of patients aged 16 years or younger who underwent keratoplasty in the Helsinki University Eye Hospital during 1968-2011. Diagnosis, preoperative status, age at the time of surgery, ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13040
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To evaluate the potential use of decellularized porcine stromal matrix (PSM) for reconstruction of corneal stroma in a rabbit model. METHODS:Ten chinchilla bastard rabbit corneas were exposed to a circular half-thickness keratotomy with a 3.0 mm diameter at the central cornea. Porcine corneas were decellulariz...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02300.x
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:The computer program laguna onhe determines optic nerve head haemoglobin (ONH Hb) on retinal photographs based on detecting colour differences. This study compares the diagnostic capacity of Laguna ONhE with that of spectral domain optical coherence tomography (OCT) and confocal tomography (HRT III). METHODS:I...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13050
更新日期:2016-11-01 00:00:00
abstract::Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2008.01210.x
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01526.x
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To examine the heritability of corneal refraction power (CR) and corneal astigmatism (AST) in older women. METHODS:Corneal refraction and AST were measured by IOL master in 52 monozygotic (MZ) and 47 dizygotic (DZ) female twin pairs aged 66-79 years. The relative contribution of genetic and environmental facto...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02332.x
更新日期:2013-03-01 00:00:00
abstract::Data on the association between hypothyroidism and glaucoma are conflicting. We sought to shed light on this by conducting a critical review and meta-analyses. The meta-analyses were conducted in adherence with the widely accepted MOOSE guidelines. Using the Medical Subject Heading (MeSH) terms: hypothyroidism, myxoed...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/aos.13412
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To report the 12 months efficacy of initial intravitreal bevacizumab or intravitreal recombinant tissue plasminogen activator (rtPA) combined with expansile gas in patients with subretinal haemorrhage caused by neovascular age-related macular degeneration (AMD). METHODS:Forty-five eyes of 45 patients with subr...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02264.x
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To evaluate the positivity rate of temporal artery biopsies (TAB) performed in suspects of giant cell arteritis (GCA) and to study the epidemiological and clinical factors associated to the biopsy result. METHODS:A retrospective, multicenter, case-control study was performed, including three hundred and thirty...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1755-3768.2012.02505.x
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:Our purpose was to evaluate the surgical outcome after intra-ocular lens exchange in patients who presented impairing visual complaints after primary multifocal intra-ocular lens (MIOL) implantation. In particular, the study was undertaken to look at the number of eyes that could be equipped with the bag-in-the...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12093
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To explore the efficacy of selective laser trabeculoplasty (SLT) within eyes with exfoliative glaucoma and history of prior argon laser trabeculoplasty (ALT). METHODS:A single-centre trial consisting of 47 patients (47 eyes) with uncontrolled exfoliative glaucoma. The main outcome measure was intraocular press...
journal_title:Acta ophthalmologica
pub_type: 临床试验,杂志文章
doi:10.1111/aos.14136
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:Metrics that capture changes in the retinal microvascular structure are relevant in the context of cardiometabolic disease development. The microvascular topology is typically quantified using monofractals, although it obeys more complex multifractal rules. We study mono- and multifractals of the retinal microv...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14598
更新日期:2020-09-16 00:00:00