Retinal oxygen saturation as a non-invasive estimate for mixed venous oxygen saturation and cardiac output.

Abstract:

PURPOSE:To investigate the correlation between retinal vessel oxygen saturation and mixed venous oxygen saturation (SvO2-mixed ) and cardiac output (CO). METHODS:Retinal arterial (SaO2-retinal ) and venous (SvO2-retinal ) oxygen saturation were measured non-invasively with dual-wavelength retinal oximetry in subjects receiving invasive measurements of SvO2-mixed and CO through right heart catheterization. Correlations were analysed using Spearman's rank correlation coefficients and linear regression models. RESULTS:Fourteen patients (median age 62.7 years, range: 21-77) were included in the analysis. When adjusted for age, SvO2-retinal showed a positive correlation with SvO2-mixed (β = 0.80, p = 0.003). Retinal arteriovenous oxygen saturation difference was significantly correlated with the inverse of CO (Spearman's ρ = 0.59, p = 0.026). CONCLUSION:This pilot study provides proof of concept for the use of retinal oximetry as a non-invasive tool to assess systemic cardiovascular function.

journal_name

Acta Ophthalmol

journal_title

Acta ophthalmologica

authors

Van Keer K,Van Keer J,Barbosa Breda J,Nassiri V,Van Cleemput J,Abegão Pinto L,Stalmans I,Vandewalle E

doi

10.1111/aos.13890

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

e308-e312

issue

2

eissn

1755-375X

issn

1755-3768

journal_volume

97

pub_type

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