Teeth-derived stem cells: A source for cell therapy.

Abstract:

:Cell therapy is one of the important therapeutic approaches in the treatment of many diseases such as cancer, degenerative diseases, and cardiovascular diseases. Among various cell types, which could be used as cell therapies, stem cell therapy has emerged as powerful tools in the treatment of several diseases. Multipotent stem cells are one of the main classes of stem cells that could originate from different parts of the body such as bone marrow, adipose, placenta, and tooth. Among several types of multipotent stem cells, tooth-derived stem cells (TDSCs) are associated with special properties such as accessible, easy isolation, and low invasive, which have introduced them as a good source for using in the treatment of several diseases such as neural injuries, liver fibrosis, and Cohrn's disease. Here, we provided an overview of TDSCs particular stem cells from human exfoliated deciduous teeth and clinical application of them. Moreover, we highlighted molecular mechanisms involved in the regulation of dental stem cells fate.

journal_name

J Cell Physiol

authors

Baniebrahimi G,Khanmohammadi R,Mir F

doi

10.1002/jcp.27270

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

2426-2435

issue

3

eissn

0021-9541

issn

1097-4652

journal_volume

234

pub_type

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