Impact of neutrophil-lymphocyte ratio on long-term outcome in patients with craniopharyngioma.

Abstract:

:Neutrophil-lymphocyte ratio (NLR) is a poor prognostic factor in many tumors including glioblastoma multiforme (GBM), colorectal, and prostate cancer. The aim of this study was to investigate the prognostic value of preoperative NLR in patients with craniopharyngioma.Around 149 patients of craniopharyngioma surgically were treated at the Department of Neurosurgery, West China Hospital from January 2008 to December 2010, including 84 males and 65 females aged from 6 to 70 years were retrospectively reviewed, and preoperative NLR was analyzed. Overall survival (OS), progression free survival (PFS), and quality of life (QOL) were evaluated.The 5-year OS and PFS rates were 81.21% and 75.84%. Preoperative NLR was significantly correlated with OS (HR = 1.44, 95% CI 1.16-1.79, P = .001) and PFS (HR = 1.46, 95% CI 1.22-1.74, P < .001). The best cut-off value of NLR was found to be 4 based on the receiver operator characteristics (ROC) curve. Patients with NLR ≥4 had a significantly worse QOL (P = .039), lower OS rate (P = .009), and PFS rate (P < .001).Preoperative NLR may be a simple, readily available, and valid predictor of long-term outcome in craniopharyngioma. We suggest that the NLR can provide effective guidance to neurosurgeons for more information about the tumor and prognostic evaluation.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Zhang J,He M,Liu Z,Song Y,Wang Y,Liang R,Chen H,Xu J

doi

10.1097/MD.0000000000012375

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

e12375

issue

37

eissn

0025-7974

issn

1536-5964

pii

00005792-201809140-00077

journal_volume

97

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Evaluation of myocardial viability in patients with acute myocardial infarction: Layer-specific analysis of 2-dimensional speckle tracking echocardiography.

    abstract:BACKGROUND:The value of layer-specific two-dimensional speckle tracking echocardiography (LS2D-STE) for evaluating viable myocardium (VM) in patients with acute myocardial infarction (AMI) was unclear, this study provides new insights into it and to make a comparison with dualisotope simultaneous acquisition single pho...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/MD.0000000000013959

    authors: Liu K,Wang Y,Hao Q,Li G,Chen P,Li D

    更新日期:2019-01-01 00:00:00

  • A child infected with severe acute respiratory syndrome coronavirus 2 presenting with diarrhea without fever and cough: A case report.

    abstract:RATIONALE:Coronavirus disease 2019 (COVID-19), now a global pandemic, has spread to a large number of countries around the world. Symptoms of COVID-19 can range from mild to severe, including fever, cough, shortness of breath, and pneumonia. Some cases even remain asymptomatic. Data regarding the epidemiological and cl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021427

    authors: Liu Q,Zhang Y,Long Y

    更新日期:2020-08-14 00:00:00

  • The catalase C-262T gene polymorphism and cancer risk: a systematic review and meta-analysis.

    abstract::Many studies suggest that catalase C-262T gene polymorphism is associated with cancer risk, but with inconsistent results. This study aimed to summarize the overall association between catalase C-262T polymorphism and cancer risk. Literature search was performed in PubMed, Embase, and other databases, studies regardin...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000000679

    authors: Shen Y,Li D,Tian P,Shen K,Zhu J,Feng M,Wan C,Yang T,Chen L,Wen F

    更新日期:2015-04-01 00:00:00

  • Management of locally advanced synchronous colorectal and prostate cancers: A case report.

    abstract:INTRODUCTION:Synchronous colorectal and prostate malignancies are uncommon, with standard treatment guidelines not yet established. Chemoradiation therapy is involved in both colorectal and prostate cancers. However, differing dosage regimens and effects of irradiation field on anatomical planes for surgery makes manag...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020336

    authors: Tey YQ,Ravi K,Chong CS,Chiong E,Ho J,Tey JCS,Ho F

    更新日期:2020-05-29 00:00:00

  • Ossifying fibroma in the mandibular angle mimicking metastatic clear cell renal cell carcinoma: A case report.

    abstract:RATIONALE:Ossifying fibroma is benign fibro-osseous neoplasm. The authors report a case of ossifying fibroma in the mandibular angle suspected as metastasis of clear cell renal cell carcinoma. PATIENT CONCERNS:A 74-year-old man presented to the primary hospital complaining of frequent urination. A tumor in the left ki...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016595

    authors: Matsuda S,Yoshimura H,Yoshida H,Taga M,Imamura Y,Kiyoshima T,Sano K

    更新日期:2019-08-01 00:00:00

  • A meta-analysis of the effects of probiotics and synbiotics in children with acute diarrhea.

    abstract:OBJECTIVE:This meta-analysis assessed the effectiveness of probiotics and synbiotics for acute diarrhea (AD) in children and investigated probiotic formulations, types of interventions, and country factors. METHODS:Randomized, double-blind, placebo-controlled trials evaluating the effects of probiotics or synbiotics o...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000016618

    authors: Yang B,Lu P,Li MX,Cai XL,Xiong WY,Hou HJ,Ha XQ

    更新日期:2019-09-01 00:00:00

  • Hedgehog Signaling in Pancreatic Fibrosis and Cancer.

    abstract::The hedgehog signaling pathway was first discovered in the 1980s. It is a stem cell-related pathway that plays a crucial role in embryonic development, tissue regeneration, and organogenesis. Aberrant activation of hedgehog signaling leads to pathological consequences, including a variety of human tumors such as pancr...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000002996

    authors: Bai Y,Bai Y,Dong J,Li Q,Jin Y,Chen B,Zhou M

    更新日期:2016-03-01 00:00:00

  • Efficacy and safety of high-viscosity cement in percutaneous vertebroplasty for treatment of Osteoporotic vertebral compression fractures: A retrospective cohort study.

    abstract::To evaluate the efficacy and safety of high viscosity bone cement in the percutaneous vertebroplasty (PVP) for treatment of single-level osteoporotic vertebral compression fractures.Eighty patients were enrolled in this study. All patients were received PVP, and they were divided into 2 groups according to the viscosi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020515

    authors: Li K,Feng H,Luo D,Zhang W,Yang K,Ji C,Liu J,Xu H

    更新日期:2020-06-05 00:00:00

  • Erratum: Risk Assessment of Hepatocellular Carcinoma Using Transient Elastography Vs. Liver Biopsy in Chronic Hepatitis B Patients Receiving Antiviral Therapy: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000002985.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/01.md.0000488768.90771.b8

    authors:

    更新日期:2016-07-01 00:00:00

  • Clinical characteristics and management of primary granulocytic sarcoma of the breast: A case report.

    abstract:RATIONALE:Primary granulocytic sarcoma of the breast is a rare and poor-prognosis malignancy. Clinicians do not have sufficient knowledge of this disease and often misdirect it as other soft tissue sarcomas or inflammation. PATIENT CONCERNS:A 42-year-old female presented with a self-discovered asymptomatic growing and...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016648

    authors: Wu HY,Liu L,Gu L,Luo YH

    更新日期:2019-08-01 00:00:00

  • Association between comorbid conditions and BADL/IADL disability in hypertension patients over age 45: Based on the China health and retirement longitudinal study (CHARLS).

    abstract::Hypertension usually coexists with other chronic conditions and can cause disability in relation to activities of daily living. We examined the association between the number and categories of comorbid conditions and disability affecting activities of daily living in hypertension patients.The data were collected from ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004536

    authors: Qian J,Ren X

    更新日期:2016-08-01 00:00:00

  • Evaluation of the association between hyperuricemia and coronary artery disease: A STROBE-compliant article.

    abstract::The aim of the study was to assess the independent contribution of hyperuricemia to coronary artery disease (CAD) confirmed by coronary angiography (CAG), and to explore associations between serum uric acid (SUA) level and CAD.We performed a retrospective cohort study of 5069 patients who underwent CAG. Patients were ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012926

    authors: Lan M,Liu B,He Q

    更新日期:2018-11-01 00:00:00

  • Acupuncture on treating angina pectoris: A systematic review.

    abstract:BACKGROUND:Coronary heart disease angina pectoris is a common clinical symptom in patients with coronary heart disease, due to coronary atherosclerotic stenosis or sputum leading to coronary insufficiency, myocardial transient ischemia, hypoxia caused by precordial pain as the main clinical manifestations Group syndrom...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018548

    authors: Wang JS,Yu XD,Deng S,Yuan HW,Li HS

    更新日期:2020-01-01 00:00:00

  • Analysis of the characteristics of optical coherence tomography angiography for retinal cavernous hemangioma: A case report.

    abstract:RATIONALE:Retinal cavernous hemangioma is a rare congenital vascular malformation with typical fundus changes. Optical coherence tomography angiography (OCTA), which is in rise in the recent years, is a rapid and noninvasive technology to assist in obtaining information regarding the blood flow changes in the fundus le...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009940

    authors: Lyu S,Zhang M,Wang RK,Gao Y,Zhang Q,Min X

    更新日期:2018-02-01 00:00:00

  • Echocardiographic Diagnosis and Outcome of Pseudoaneurysm of the Mitral-Aortic Intervalvular Fibrosa: Results of a Single-Center Experience in Beijing.

    abstract::Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare but potentially fatal entity. Early diagnosis and surgical treatment are particularly important to decrease risk of mortality. The purpose of this study was to explore the echocardiographic characteristics and outcome of P-MAIVF and to evalu...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003116

    authors: Han J,He Y,Gu X,Sun L,Zhao Y,Liu W,Zhang Y,Yang X,Li Y

    更新日期:2016-03-01 00:00:00

  • Mastocytosis among elderly patients: A multicenter retrospective French study on 53 patients.

    abstract::Mastocytosis is a heterogeneous group of diseases with a young median age at diagnosis. Usually indolent and self-limited in childhood, the disease can exhibit aggressive progression in mid-adulthood. Our objectives were to describe the characteristics of the disease when diagnosed among elderly patients, for which ra...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000003901

    authors: Rouet A,Aouba A,Damaj G,Soucié E,Hanssens K,Chandesris MO,Livideanu CB,Dutertre M,Durieu I,Grandpeix-Guyodo C,Barète S,Bachmeyer C,Soria A,Frenzel L,Fain O,Grosbois B,de Gennes C,Hamidou M,Arlet JB,Launay D,Lavign

    更新日期:2016-06-01 00:00:00

  • Ultrasonographic manifestations of a rare granular cell tumor of the accessory breast: A case report.

    abstract:RATIONALE:The ultrasound manifestations of granular cell tumor (GCT) is a consequence of the histopathological characteristic of the tumor and can be distinguished from breast cancer. PATIENT CONCERNS:A GCT is a rare, benign, hyperplasia-based lesion. Approximately 1% to 2% of GCTs are malignant. About 5% to15% of the...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009462

    authors: Liu H,Tao M,Ding H,Zhang P

    更新日期:2018-01-01 00:00:00

  • Validation of the Chinese version of the Mini Sarcopenia Risk Assessment questionnaire in community-dwelling older adults.

    abstract::A new sarcopenia screening tool named Mini Sarcopenia Risk Assessment (MSRA) has recently been developed, which showed a reasonable sensitivity and specificity.We cross-culturally adapted and validated the Chinese version of the MSRA in a population of community-dwelling older adults.We conducted a cross-sectional stu...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012426

    authors: Yang M,Hu X,Xie L,Zhang L,Zhou J,Lin J,Wang Y,Li Y,Han Z,Zhang D,Zuo Y,Li Y,Wu L

    更新日期:2018-09-01 00:00:00

  • Therapeutic approach to IgG4-related disease: A systematic review.

    abstract::To review the reported evidence on the therapeutic management of IgG4-related disease (IgG4-RD) in clinical practice.A systematic search of the literature was conducted. The primary outcome measured was the rate of efficacy of first-line therapeutic approaches. Secondary outcomes measured included the rate of disease ...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000004002

    authors: Brito-Zerón P,Kostov B,Bosch X,Acar-Denizli N,Ramos-Casals M,Stone JH

    更新日期:2016-06-01 00:00:00

  • Association Between Race/Ethnicity and Survival of Melanoma Patients in the United States Over 3 Decades: A Secondary Analysis of SEER Data.

    abstract:UNLABELLED:Melanoma is a treatable and preventable skin cancer. It is responsible for 75% of deaths among all skin cancers. Previous studies have found that race/ethnicity may play a role in survival among melanoma patients. However, there are no studies that cover 30 years and take race into account for the U.S. POPU...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003315

    authors: Ward-Peterson M,Acuña JM,Alkhalifah MK,Nasiri AM,Al-Akeel ES,Alkhaldi TM,Dawari SA,Aldaham SA

    更新日期:2016-04-01 00:00:00

  • Effects of Referral Bias on Estimates of Anal Intraepithelial Neoplasia Progression and Regression Rates in a 3-State Markov Model.

    abstract::The study aim is to compare anal intraepithelial neoplasia (AIN) progression and regression rates in a cytology inception cohort to estimates based on the subcohort referred for ≥1 high-resolution anoscopies (HRAs).A cytology-based retrospective cohort was assembled including the anal cytology histories and invasive a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001476

    authors: Mathews WC,Cachay ER,Agmas W,Jackson C

    更新日期:2015-09-01 00:00:00

  • Antibiotic prescribing trends in a pediatric population in Lithuania in 2003-2012: Observational study.

    abstract::The purpose of this study was to determine the trends in consumption of antibiotics and evaluate the antibiotic prescription rates in the pediatric population in Lithuania during 2003 to 2012.A cross-sectional study. Data of systemic antibiotic use in pediatric population for outpatient treatment was derived from Nati...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017220

    authors: Karinauske E,Kasciuskeviciute S,Morkuniene V,Garuoliene K,Kadusevicius E

    更新日期:2019-11-01 00:00:00

  • The drug use to treat community-acquired pneumonia in children: A cross-sectional study in China.

    abstract::To evaluate the rationality of drug use to treat community-acquired pneumonia (CAP) in children of a Chinese hospital using a set of developed indicators.We performed a retrospective cross-sectional study in West China Second University Hospital. Hospitalized children (0-18 years old) diagnosed with CAP from October 2...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013224

    authors: Mi X,Li W,Zhang L,Li J,Zeng L,Huang L,Chen L,Song H,Huang Z,Lin M

    更新日期:2018-11-01 00:00:00

  • Genetic Characteristics of CRF01_AE Among Newly Diagnosed HIV-1-Infected 16- to 25-Year Olds in 3 Geographic Regions of Guangxi, China.

    abstract::The aim of this study was to analyze the distribution of clusters and drug resistance of CRF01_AE among newly diagnosed, treatment-naïve HIV-infected teenagers and young adults in 3 major HIV-affected geographic regions of Guangxi Province, including the cities of Hezhou, Liuzhou, and Nanning. Samples were sequentiall...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000894

    authors: Zhang J,Shen ZY,Li Z,Liang SJ,He C,Liang FX,Feng Y,Li JJ,Ruan YH,Zhou YJ,Shao YM,Xing H,Liao LJ

    更新日期:2015-05-01 00:00:00

  • Extramedullary Soft Tissue Involvement and Discrepant Osseous Uptake on Tc-99m MDP and Ga-67 Citrate Scintigraphy in a Patient With Multiple Myeloma: A Case Report and Literature Review.

    abstract::Multiple myeloma (MM) is a plasma cell neoplasm with skeletal destruction which could also spread to extramedullary regions. Common diagnostic imaging modalities include skeletal radiography, computed tomography (CT), magnetic resonance imaging (MRI). Recently, PET/CT is proposed as an ideal tomographic tool for diagn...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000995

    authors: Tsai SY,Wang SY,Shiau YC,Wu YW

    更新日期:2015-06-01 00:00:00

  • Epidemic classical heat stroke: clinical characteristics and course of 28 patients.

    abstract::Patients with classical heat stroke are different in many ways from those with exertional injury; contrasts included difference in demographic factors, prior general health, in-hospital complications and laboratory abnormalities (lactate, liver enzymes, pH, electrolytes). Severe hyperkalemia, acute renal failure, rhab...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:

    authors: Hart GR,Anderson RJ,Crumpler CP,Shulkin A,Reed G,Knochel JP

    更新日期:1982-05-01 00:00:00

  • Traumatic intradural ruptured lumbar disc with a spinal compression fracture: A case report.

    abstract:RATIONALE:We present a rare case of a traumatic intradural ruptured disc associated with a mild vertebral body compression fracture along with a review of the relevant medical literature. An intradural ruptured disc often occurs due to chronic degenerative diseases and is rarely due to trauma. It can cause irreversible...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019037

    authors: Lee G,Han MS,Lee SK,Moon B,Lee JK

    更新日期:2020-02-01 00:00:00

  • The use of apatinib in treating primary pleural synovial sarcoma: A case report.

    abstract:RATIONALE:Apatinib is an oral tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor-2. It has been shown that apatinib is effective and safe for treatment of multiple solid tumors, including gastric cancer, liver cancer, non-small-cell lung cancer, and breast cancer. However, there is currentl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018382

    authors: Chen S,Zhang K,Wan X,Chen Y,Ma S,Deng Q

    更新日期:2019-12-01 00:00:00

  • Influenza A with hemorrhagic shock and encephalopathy syndrome in an adult: A case report.

    abstract:INTRODUCTION:Hemorrhagic shock and encephalopathy syndrome (HSES) is a type of acute encephalopathy mainly seen in infants. It is a syndrome encompassing an onset of high fever, disturbance of consciousness, convulsion, and shock that rapidly progresses to watery diarrhea and liver and renal dysfunctions. It is extreme...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015012

    authors: Fukuda M,Yoshida T,Moroki M,Hirayu N,Nabeta M,Nakamura A,Uzu H,Takasu O

    更新日期:2019-04-01 00:00:00

  • Chronic postsurgical pain and neuropathic symptoms after abdominal hysterectomy: A silent epidemic.

    abstract::Chronic postsurgical pain (CPSP) is an important clinic problem. It is assessed that prevalence of chronic pain extends to 30% but it is contended that there are various risk factors. We aimed to evaluate the prevalence of chronic pain after hysterectomy, risk factors of chronicity, neuropathic features of pain, and s...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004484

    authors: Beyaz SG,Özocak H,Ergönenç T,Palabıyık O,Tuna AT,Kaya B,Erkorkmaz Ü,Akdemir N

    更新日期:2016-08-01 00:00:00