Hedgehog Signaling in Pancreatic Fibrosis and Cancer.

abstract：:This study aimed to assess the associations of human leukocyte antigen (HLA)-DR and interleukin (IL)-18 gene polymorphisms with hepatitis B virus (HBV).Clinical data were retrospectively reviewed between December 2006 and December 2015 at Xiangyang Central Hospital. HBV patients were assigned to the high and low viral...

journal_title：Medicine

authors： Jiang H,Cao F,Cao H,Rao Q,Yang Y

更新日期：2018-07-01 00:00:00

abstract：RATIONALE:Immunoglobulin G4-related disease (IgG4-RD) is regarded as an immune-mediated systemic fibroinflammatory disease. Several studies have linked IgG4-RD to infections such as tuberculosis and actinomycosis. However, the coexistence of IgG4-RD and non-tuberculous mycobacterium (NTM) in a single pulmonary nodule h...

journal_title：Medicine

authors： Bae K,Jung An H,Jeon KN,Hyun Song D,Kim SH,Kim HC

更新日期：2019-11-01 00:00:00

abstract：:The purpose of this study was to determine the clinical association factors between osteoporosis and cerebral artery disease in Korean population. Two hundred nineteen postmenopausal women and men undergoing cerebral computed tomography angiography were enrolled in this study to evaluate the cerebral artery disease by...

journal_title：Medicine

authors： Jin ES,Jeong JH,Lee B,Im SB

更新日期：2017-03-01 00:00:00

abstract：:The association between the hepatitis C virus (HCV) infection and the risk of myocardial infarction (MI) and stroke has been previously investigated. However, the association between the HCV infection and the risk of venous thromboembolism (VTE) has not been extensively discussed. Using the Longitudinal Health Insuran...

journal_title：Medicine

authors： Wang CC,Chang CT,Lin CL,Lin IC,Kao CH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The small renal masses (SRMs) were defined that the diameter of renal masses measured by enhanced image was ≤4 cm. The diagnostic accuracy of contrast-enhanced ultrasound (CEUS) for SRMs is apparently variable among previous studies. Hence, this study will evaluate the diagnostic accuracy of CEUS in the iden...

journal_title：Medicine

authors： Wu JF,Wu C,Wang YL,Wang ZP

更新日期：2020-07-17 00:00:00

abstract：:Unplanned reoperations have not been studied extensively in pediatric patients, especially concerning risk factors. We aim to estimate the rate of unplanned reoperations and to determine the associated factors in pediatric general surgical specialties.This analysis included a retrospective case-control study of unplan...

journal_title：Medicine

authors： Li A,Zhu H,Zhou H,Liu J,Deng Y,Liu Q,Guo C

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-α) is a potent immune-inflammatory mediator involved in the regulation of bone resorption. The single nucleotide polymorphism G-308A in the TNF-α gene increases the level of this cytokine. This phenomenon is also related to several diseases. Although the association between T...

journal_title：Medicine

authors： Mo YY,Zeng XT,Weng H,Cen Y,Zhao Q,Wen X

更新日期：2016-08-01 00:00:00

abstract：:It is shown that there are strong associations between nonalcoholic fatty liver disease (NAFLD) and endothelial dysfunction. The aim of our study was to reveal whether steatosis or fibrosis score is more important in the development of endothelial dysfunction in patients with NAFLD in a prospective manner.This cross-s...

journal_title：Medicine

authors： Sapmaz F,Uzman M,Basyigit S,Ozkan S,Yavuz B,Yeniova A,Kefeli A,Asilturk Z,Nazligül Y

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the outcomes of patients with pathologic T0 esophageal carcinoma after neoadjuvant therapy and surgery. METHODS:We searched PubMed, Embase, Cochrane Library, and Medline databases from inception up to November 12, 2016. The meta-analysis was performed to compare odds ra...

journal_title：Medicine

authors： Lv HW,Li Y,Zhou MH,Cheng JW,Xing WQ

更新日期：2017-06-01 00:00:00

abstract：:The clinical significance of ineffective esophageal motility (IEM) together with multiple rapid swallow (MRS) has not been yet evaluated in the Chicago Classification v3.0. This study evaluated the adjunctive role of MRS in IEM and determined the criteria of abnormal MRS to maximize the utility of IEM. We analyzed 186...

journal_title：Medicine

authors： Min YW,Shin I,Son HJ,Rhee PL

更新日期：2015-10-01 00:00:00

abstract：RATIONALE:Frontometaphyseal dysplasia (FMD) is a dominant X-linked rare disease caused by mutations of FLNA. The distinctive features of FMD include skeletal dysplasia, facial dysmorphism, extremities anomalies, deafness, cleft palate and eye anterior segment anomalies, yet none of the complications, such as acro-osteo...

journal_title：Medicine

authors： Xie H,Xue L,Hua W,Jia B,Zhang L,Li L

更新日期：2018-07-01 00:00:00

abstract：:The Smith-Magenis syndrome (SMS) is a complex and rare congenital condition that is characterized by minor craniofacial anomalies, short stature, sleep disturbances, behavioral, and neurocognitive abnormalities, as well as variable multisystemic manifestations. Little is reported about spinal deformity associated with...

journal_title：Medicine

authors： Li Z,Shen J,Liang J,Sheng L

更新日期：2015-05-01 00:00:00

abstract：RATIONALE:Primary intracranial leiomyosarcoma (LMS) is an extremely rare tumor in the central nervous system (CNS), and usually seen in immunocompromised individuals. Only a few cases of primary intracranial LMS have been documented in the literature and no study focused on their MRI findings. We reported a case of pri...

journal_title：Medicine

authors： Li XL,Ren J,Niu RN,Jiang X,Xu GH,Zhou P,Cheng ZZ

更新日期：2019-04-01 00:00:00

abstract：RATIONALE:Tibial hemimelia is known as a rare congenital lower limb deficiency. It has been classified into different types based on Jones classification, and the traditional treatment of tibial hemimelia is amputation. Here we present a variant and unclassified case of tibial hemimelia, which was caused by osteomyelit...

journal_title：Medicine

authors： Yu L,Yu G,Deng K,Wang G

更新日期：2019-01-01 00:00:00

abstract：:Previous series presented the timing between embolization and surgery in a wide range on the basis of their experience rather than supportive data. And comparative studies were limited to small samples. In addition, there is no study publishing the timing by considering both safety and efficacy of embolization. The ai...

journal_title：Medicine

authors： Tang B,Ji T,Guo W,Tang X,Jin L,Dong S,Xie L

更新日期：2018-06-01 00:00:00

abstract：:We conducted a single-center retrospective study to compare the characteristics of Takayasu arteritis (TA) among white, North African, and black patients in a French tertiary care center (Hospital Pitié-Salpêtrière, Paris). Eighty-two patients were studied (82.9% female) during a median follow-up of 5.1 years (range, ...

journal_title：Medicine

authors： Arnaud L,Haroche J,Limal N,Toledano D,Gambotti L,Chalumeau NC,Boutin DLTH,Cacoub P,Cluzel P,Koskas F,Kieffer E,Piette JC,Amoura Z

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Periodontitis is a common disease with an unclear pathological mechanism. No precise consensus has been reached to evaluate the association between the IL-10 rs1800872 (- 592, -590, -597 C>A) polymorphism and periodontal disease. Thus, we performed this meta-analysis to collect more evidence-based informatio...

journal_title：Medicine

authors： Wang Z,Li Y,Zhou Y,Qiao Y

更新日期：2019-10-01 00:00:00

abstract：:Systemic vasculitis (SV) involving abdominal structures usually has a poor prognosis. Gallbladder vasculitis (GV) has been reported as part of SV (GB-SV) and focal single-organ vasculitis (GB-SOV). We analyzed clinical and histologic characteristics of patients with GV to identify features that differentiate GB-SOV fr...

journal_title：Medicine

authors： Hernández-Rodríguez J,Tan CD,Rodríguez ER,Hoffman GS

更新日期：2014-11-01 00:00:00

abstract：:It is not clearly established if coinfections are more severe than single viral respiratory infections.The aim of the study was to study and to compare simple infections and viral coinfections of respiratory syncytial virus (RSV) in hospitalized children.From September 2005 to August 2013, a prospective study was cond...

journal_title：Medicine

authors： Calvo C,García-García ML,Pozo F,Paula G,Molinero M,Calderón A,González-Esguevillas M,Casas I

更新日期：2015-10-01 00:00:00

abstract：:Nafamostat mesilate (NM), a synthetic serine protease inhibitor, has been used increasingly as an anticoagulant during continuous renal replacement therapy (CRRT). However, there, are limited data from randomized studies on NM use in patients with a bleeding tendency. This prospective study evaluated the efficacy and ...

journal_title：Medicine

authors： Choi JY,Kang YJ,Jang HM,Jung HY,Cho JH,Park SH,Kim YL,Kim CD

更新日期：2015-12-01 00:00:00

abstract：RATIONALE:The use of musculoskeletal ultrasound (MU) method in the diagnosis of shoulder pain and injury and guidance of injection and pain blocking has been established. However, the treatment of posthemiplegic shoulder pain (HSP) with MU-guided precise physical therapy has not been reported. PATIENT CONCERNS:Here, w...

journal_title：Medicine

authors： Zhang J,Li Y,Wang H

更新日期：2017-12-01 00:00:00

abstract：:Metabolic syndrome (MetS) is a major public health concern. Efficient screening requires criteria that are economical, easily accessible, and applicable for all populations. We aimed to compare the discriminating ability of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) for the diagn...

journal_title：Medicine

authors： Yang H,Xin Z,Feng JP,Yang JK

更新日期：2017-09-01 00:00:00

abstract：:The best method to ligate the arteries during laparoscopic cholecystectomy or appendectomy remains controversy. The aim of this study is to introduce a new approach during laparoscopic combined cholecystectomy and appendectomy using a monopolar electrocautery to seal the cystic and appendix arteries. We retrospectivel...

journal_title：Medicine

authors： Liu GB,Mao YY,Yang CP,Cao JL

更新日期：2018-03-01 00:00:00

abstract：:This study aims to evaluate the clinical and radiographic treatment outcomes of comminuted Mason type II radial head fractures, which underwent open reduction and internal fixation (ORIF) using a new implant (mother-child screw, MCS).This study included 16 patients (7 male and 9 female patients; mean age: 40.9 years, ...

journal_title：Medicine

authors： Shi Y,Wang GF,Mei K,Zhang J,Yun CJ,Qian C,Sun JY

更新日期：2018-03-01 00:00:00

abstract：:Several scoring systems are commonly used to evaluate severity in patients with traumatic injuries. However, there is no generally accepted standard scoring system to assess the severity of thoracic trauma, specifically in patients who have sustained severe injuries. The present study aimed to evaluate the validity of...

journal_title：Medicine

authors： Moon SH,Kim JW,Byun JH,Kim SH,Choi JY,Jang IS,Lee CE,Yang JH,Kang DH,Kim KN,Park HO

更新日期：2017-10-01 00:00:00

abstract：:There are limited population-based studies on the progress of oseltamivir therapy for influenza infection.Using insurance claims data of 2005, 2009, and 2010, the authors established an "in-time" cohort and a "lag-time" cohort representing influenza patients taking the medicine within and not within 1 week to examine ...

journal_title：Medicine

authors： Wang CB,Chiu ML,Lin PC,Liang WM,Chen CY,Chang YJ,Wu TN,Wang JH,Sung FC

更新日期：2015-07-01 00:00:00

abstract：:[This corrects the article DOI: 10.1097/MD.0000000000006423.]. ...

journal_title：Medicine

authors：

更新日期：2017-04-28 00:00:00

abstract：BACKGROUND:Allergic rhinitis is a major chronic inflammatory disease of the respiratory tract. A large number of epidemiological investigations have shown that the prevalence of allergic rhinitis (AR) is increasing, resulting in a large burden of disease. Desensitizing drugs such as nasal glucocorticoids and antihistam...

journal_title：Medicine

authors： Bao H,Si D,Gao L,Sun H,Shi Q,Yan Y,Damchaaperenlei D,Li C,Yu M,Li Y

更新日期：2018-12-01 00:00:00

abstract：:The purpose of this study was to evaluate the effects of salvage chemotherapy on recurrent or persistent ovarian clear cell carcinoma (CCC) with the goal of identifying a more rational treatment regimen for this lethal disease.The medical records of patients with CCC were retrospectively reviewed to select patients th...

journal_title：Medicine

authors： Bai H,Sha G,Cao D,Yang J,Chen J,Wang Y,Lang J,Shen K,Zhang Z

更新日期：2015-07-01 00:00:00

abstract：:Fine needle aspiration (FNA) is the procedure of choice for evaluating thyroid nodules. It is indicated for nodules >2 cm, even in cases of very low suspicion of malignancy. FNA has associated risks and expenses. In this study, we developed an image analysis model using a deep learning algorithm and evaluated if the a...

journal_title：Medicine

authors： Song J,Chai YJ,Masuoka H,Park SW,Kim SJ,Choi JY,Kong HJ,Lee KE,Lee J,Kwak N,Yi KH,Miyauchi A

更新日期：2019-04-01 00:00:00