FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway.

abstract：:Conifer wood is an exceptionally stiff and strong material when its cellulose microfibrils are well aligned. However, it is not well understood how the polymer components cellulose, hemicelluloses and lignin co-operate to resist tensile stress in wood. From X-ray scattering, neutron scattering and spectroscopic data, ...

journal_title：Scientific reports

authors： Thomas LH,Altaner CM,Forsyth VT,Mossou E,Kennedy CJ,Martel A,Jarvis MC

更新日期：2021-01-11 00:00:00

abstract：:Bloodstain Pattern Analysis is a forensic discipline in which, among others, the position of victims can be determined at crime scenes on which blood has been shed. To determine where the blood source was investigators use a straight-line approximation for the trajectory, ignoring effects of gravity and drag and thus ...

journal_title：Scientific reports

authors： Laan N,de Bruin KG,Slenter D,Wilhelm J,Jermy M,Bonn D

更新日期：2015-06-22 00:00:00

abstract：:To assess the response of lichen elemental compositions to road traffic and species difference in the context of high dust input and anthropogenic emissions, two foliose epiphytic lichens (Phaeophyscia hirtuosa, PHh; Candelaria fibrosa, CAf) were sampled near a road adjacent to Dolon Nor Town (Duolun County, Inner Mon...

journal_title：Scientific reports

authors： Liu HJ,Wang JG,Xia Y,Yang MJ,Liu SW,Zhao LC,Guo XP,Jiang YJ,Li X,Wu QF,Fang SB

更新日期：2017-07-17 00:00:00

abstract：:There are three sex ratio strategies (SRS) in nature-male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton's local mate competition (LMC) and Clark's local resource compe...

journal_title：Scientific reports

authors： Wang Y,Wang R,Li Y,Sam Ma Z

更新日期：2016-12-23 00:00:00

abstract：:Algae-bacteria interaction is one of the main factors underlying the formation of harmful algal blooms (HABs). The aim of this study was to develop a genome-wide high-throughput screening method to identify HAB-influenced specific interactive bacterial metabolites using a comprehensive collection of gene-disrupted E. ...

journal_title：Scientific reports

authors： Heo J,Cho K,Kim U,Cho DH,Ko S,Tran QG,Lee YJ,Ryu CM,Kim HS

更新日期：2020-06-30 00:00:00

abstract：:Petunia × hybrida cv 'Mitchell Diploid' floral volatile benzenoid/phenylpropanoid (FVBP) biosynthesis ultimately produces floral volatiles derived sequentially from phenylalanine, cinnamic acid, and p-coumaric acid. In an attempt to better understand biochemical steps after p-coumaric acid production, we cloned and ch...

journal_title：Scientific reports

authors： Kim JY,Swanson RT,Alvarez MI,Johnson TS,Cho KH,Clark DG,Colquhoun TA

更新日期：2019-06-20 00:00:00

abstract：:The pristine lignin molecules contain multiple reactive hydroxyl [OH] groups, some of which undergo limited polymerization depending on their configuration (aromatic or aliphatic) or conformation. The key issue in lignin-polymerization is to quantify the number of hydroxyl groups in the pristine molecules for subseque...

journal_title：Scientific reports

authors： Park IK,Sun H,Kim SH,Kim Y,Kim GE,Lee Y,Kim T,Choi HR,Suhr J,Nam JD

更新日期：2019-05-07 00:00:00

abstract：:Structured Progressive Circuit Class Therapy (SPCCT) was developed based on task-oriented therapy, providing benefits to patients' motivation and motor function. Training with Motor Imagery (MI) alone can improve gait performance in stroke survivors, but a greater effect may be observed when combined with SPCCT. Healt...

journal_title：Scientific reports

authors： Bovonsunthonchai S,Aung N,Hiengkaew V,Tretriluxana J

更新日期：2020-04-24 00:00:00

abstract：:Microactuators are the most distinctive and challenging microdevices among micro electromechanical systems (MEMS) relative to microsensors or electronic circuits. Soft and flexible microactuators have been achieved by introducing polymers as structural materials in addition to conventional materials. Expanding the app...

journal_title：Scientific reports

authors： Konishi S,Oya F

更新日期：2019-10-09 00:00:00

abstract：:Serum and cerebrospinal fluid (CSF) levels of α-fetoprotein and β-subunit of human chorionic gonadotropin are used as biomarkers for the management of central nervous system (CNS) germ cell tumors (GCTs). However, additional discriminating biomarkers are required. Especially, biomarkers to differentiate non-germinomat...

journal_title：Scientific reports

authors： Takayasu T,Shah M,Dono A,Yan Y,Borkar R,Putluri N,Zhu JJ,Hama S,Yamasaki F,Tahara H,Sugiyama K,Kurisu K,Esquenazi Y,Ballester LY

更新日期：2020-08-31 00:00:00

abstract：:The elemental two-dimensional (2D) materials such as graphene, silicene, germanene, and black phosphorus have attracted considerable attention due to their fascinating physical properties. Structurally they possess the honeycomb or distorted honeycomb lattices, which are composed of six-atom rings. Here we find a new ...

journal_title：Scientific reports

authors： Li P,Luo W

更新日期：2016-05-06 00:00:00

abstract：:Solution-based methods represent the most widespread approach used to deposit hybrid organic-inorganic perovskite films for low-cost but efficient solar cells. However, solution-process techniques offer limited control over film morphology and crystallinity, and most importantly do not allow sequential film deposition...

journal_title：Scientific reports

authors： Bonomi S,Marongiu D,Sestu N,Saba M,Patrini M,Bongiovanni G,Malavasi L

更新日期：2018-10-18 00:00:00

abstract：:The use of engineered viral strains such as gene therapy vectors and oncolytic viruses (OV) to selectively destroy cancer cells is poised to make a major impact in the clinic and revolutionize cancer therapy. In particular, several studies have shown that OV therapy is safe and well tolerated in humans and can infect ...

journal_title：Scientific reports

authors： Dornan MH,Krishnan R,Macklin AM,Selman M,El Sayes N,Son HH,Davis C,Chen A,Keillor K,Le PJ,Moi C,Ou P,Pardin C,Canez CR,Le Boeuf F,Bell JC,Smith JC,Diallo JS,Boddy CN

更新日期：2016-05-26 00:00:00

abstract：:Prediction of infection trends, estimating the efficacy of contact tracing, testing or impact of influx of infected are of vital importance for administration during an ongoing epidemic. Most effective methods currently are empirical in nature and their relation to parameters of interest to administrators are not evid...

journal_title：Scientific reports

authors： Raghavan M,Sridharan KS,Mandayam Rangayyan Y

更新日期：2020-10-06 00:00:00

abstract：:Radionuclide molecular imaging of HER2 expression in disseminated cancer enables stratification of patients for HER2-targeted therapies. DARPin G3, a small (14 kDa) engineered scaffold protein, is a promising probe for imaging of HER2. We hypothesized that position (C- or N-terminus) and composition (hexahistidine or ...

journal_title：Scientific reports

authors： Vorobyeva A,Schulga A,Konovalova E,Güler R,Löfblom J,Sandström M,Garousi J,Chernov V,Bragina O,Orlova A,Tolmachev V,Deyev SM

更新日期：2019-06-28 00:00:00

abstract：:The damping properties and specifically the bend losses of polymer optical fibres (POFs) have so far only been documented by experimental work, investigating bending parameters such as bending radius, length, and distance of the bends. Even though damping mechanisms and causes are well-known, no simple, generally vali...

journal_title：Scientific reports

authors： Lustermann B,Quandt BM,Ulrich S,Spano F,Rossi RM,Boesel LF

更新日期：2020-07-17 00:00:00

abstract：:Beta-glucans are a heterologous group of fibrous glucose polymers that are a major constituent of cell walls in Ascomycetes and Basidiomycetes fungi. Synthesis of β (1,3)- and (1,6)-glucans is coordinated with fungal cell growth and development, thus, is under tight genetic regulation. Here, we report that β-glucan sy...

journal_title：Scientific reports

authors： Park HS,Man Yu Y,Lee MK,Jae Maeng P,Chang Kim S,Yu JH

更新日期：2015-05-11 00:00:00

abstract：:Kidney dysfunction, a deleterious effect of obesity, is now recognized as a relevant health risk. Chemokine (C-C Motif) Ligand 2 (CCL2) is one of the critical chemokines that play a vital role in the development of obesity-related metabolic disease. We aim to measure the changes in urinary CCL2 in our patients before ...

journal_title：Scientific reports

authors： Said SB,Loo GH,Kosai NR,Rajan R,Mohd R,Wahab AA,Shah SA

更新日期：2020-01-21 00:00:00

abstract：:A larger amount of sequence data in private and public databases produced by next-generation sequencing put new challenges due to limitation associated with the alignment-based method for sequence comparison. So, there is a high need for faster sequence analysis algorithms. In this study, we developed an alignment-fre...

journal_title：Scientific reports

authors： Saw AK,Raj G,Das M,Talukdar NC,Tripathy BC,Nandi S

更新日期：2019-03-06 00:00:00

abstract：:Arctic river watersheds are important components of the global climate system and show an amplified response to climate change. Here, we characterize origins and transformations of dissolved organic matter (DOM) in five major Arctic rivers (Kolyma, Lena, Yenisei, Ob, Mackenzie) over 3 years with seasonal sampling peri...

journal_title：Scientific reports

authors： Kaiser K,Canedo-Oropeza M,McMahon R,Amon RMW

更新日期：2017-10-19 00:00:00

abstract：:Historical records indicate that extensive cultural, commercial and technological interaction occurred between European and Asian populations. What have been the biological consequences of these contacts in terms of gene flow? We systematically estimated gene flow between Eurasian groups using genome-wide polymorphism...

journal_title：Scientific reports

authors： Qin P,Zhou Y,Lou H,Lu D,Yang X,Wang Y,Jin L,Chung YJ,Xu S

更新日期：2015-04-02 00:00:00

abstract：:Hydrogen recovery through solar-driven biomass conversion by photo-fermentative bacteria (PFB) has been regarded as a promising way for sustainable energy production. However, a considerable fraction of organic substrate was consumed for the growth of PFB as biocatalysts, furthermore, these PFB were continuously washe...

journal_title：Scientific reports

authors： Xie GJ,Liu BF,Wang RQ,Ding J,Ren HY,Zhou X,Ren NQ

更新日期：2015-11-05 00:00:00

abstract：:Our previous studies indicated that combination of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and PPARγ ligand Troglitazone (TZD), can induce significant apoptosis in various TRAIL-resistant prostate and hepatocellular carcinoma (HCC) cells. These also suggested serine/threonine kinase AMP-activat...

journal_title：Scientific reports

authors： Ke R,Vishnoi K,Viswakarma N,Santha S,Das S,Rana A,Rana B

更新日期：2018-04-03 00:00:00

abstract：:There is a need to develop economical, efficient and widely available therapeutic approaches to enhance the rate of skin wound healing. The optimal outcome of wound healing is restoration to the pre-wound quality of health. In this study we investigate the cellular response to biological stimuli using functionalized n...

journal_title：Scientific reports

authors： Bradshaw M,Ho D,Fear MW,Gelain F,Wood FM,Iyer KS

更新日期：2014-11-11 00:00:00

abstract：:Although the GW approximation is recognized as one of the most accurate theories for predicting materials excited states properties, scaling up conventional GW calculations for large systems remains a major challenge. We present a powerful and simple-to-implement method that can drastically accelerate fully converged ...

journal_title：Scientific reports

authors： Gao W,Xia W,Gao X,Zhang P

更新日期：2016-11-11 00:00:00

abstract：:New techniques for the field detection of inorganic improvised explosive devices (IEDs) are urgently developed. Although ion mobility spectrometry (IMS) has been proved to be the most effective method for screening organic explosives, it still faces a major challenge to detect inorganic explosives owing to their low v...

journal_title：Scientific reports

authors： Peng L,Hua L,Wang W,Zhou Q,Li H

更新日期：2014-10-16 00:00:00

abstract：:This paper reports a facile and green method for conversion of graphene oxide (GO) into graphene by low-temperature heating (80 °C) in the presence of a glass wafer. Compared to conventional GO chemical reduction methods, the presented approach is easy-scalable, operationally simple, and based on the use of a non-toxi...

journal_title：Scientific reports

authors： Rabchinskii MK,Dideikin AT,Kirilenko DA,Baidakova MV,Shnitov VV,Roth F,Konyakhin SV,Besedina NA,Pavlov SI,Kuricyn RA,Lebedeva NM,Brunkov PN,Vul' AY

更新日期：2018-09-20 00:00:00

abstract：:Although the link between sleep disturbances and dopamine (DA)-related neurological and neuropsychiatric disorders is well established, the impact of sleep alterations on neuronal activity of midbrain DA-ergic structures is currently unknown. Here, using wildtype C57Bl mice, we investigated the circadian- and sleep-re...

journal_title：Scientific reports

authors： Fifel K,Meijer JH,Deboer T

更新日期：2018-05-17 00:00:00

abstract：:MBL2 gene encodes mannose-binding lectin, is a member of innate immune system. Earlier studies revealed that MBL2 gene variants, rs1800451, rs1800450, rs5030737, rs7096206, rs11003125 and rs7095891 are associated with impaired serum level and susceptibility to TB, but their results are inconsistent. A meta-analysis wa...

journal_title：Scientific reports

authors： Areeshi MY,Mandal RK,Akhter N,Dar SA,Jawed A,Wahid M,Mahto H,Panda AK,Lohani M,Haque S

更新日期：2016-11-23 00:00:00

abstract：:Yield-phenology relation is a critical issue affecting rainfed maize field productivity in semiarid east African Plateau (EAP). We first introduced Chinese ridge-furrow mulching (RFM) system to EAP, using three maize cultivars with early-, mid- and late-maturing traits as test materials. A two-year field experiment wa...

journal_title：Scientific reports

authors： Mo F,Wang JY,Li FM,Nguluu SN,Ren HX,Zhou H,Zhang J,Kariuki CW,Gicheru P,Kavagi L,Cheruiyot WK,Xiong YC

更新日期：2017-06-12 00:00:00