Evaluation system and web infrastructure for the second cryo-EM model challenge.

Abstract:

:An evaluation system and a web infrastructure were developed for the second cryo-EM model challenge. The evaluation system includes tools to validate stereo-chemical plausibility of submitted models, check their fit to the corresponding density maps, estimate their overall and per-residue accuracy, and assess their similarity to reference cryo-EM or X-ray structures as well as other models submitted in this challenge. The web infrastructure provides a convenient interface for analyzing models at different levels of detail. It includes interactively sortable tables of evaluation scores for different subsets of models and different sublevels of structure organization, and a suite of visualization tools facilitating model analysis. The results are publicly accessible at http://model-compare.emdatabank.org.

journal_name

J Struct Biol

authors

Kryshtafovych A,Adams PD,Lawson CL,Chiu W

doi

10.1016/j.jsb.2018.07.006

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

96-108

issue

1

eissn

1047-8477

issn

1095-8657

pii

S1047-8477(18)30164-3

journal_volume

204

pub_type

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