Regulation of the β-hemolysin gene cluster of Streptococcus anginosus by CcpA.

abstract：:This study was initiated to improve E. coli succinate production by engineering the E. coli global transcription factor, Cra (catabolite repressor/activator). Random mutagenesis libraries were generated through error-prone PCR of cra. After re-screening and mutation site integration, the best mutant strain was Tang154...

journal_title：Scientific reports

authors： Zhu LW,Xia ST,Wei LN,Li HM,Yuan ZP,Tang YJ

更新日期：2016-11-04 00:00:00

abstract：:Sleep problems are considered a core symptom of depression. However, there is little information about the comorbidity of sleep problems and depression in low- and middle-income countries (LMICs), and whether sleep problems with depression confer additional risk for decrements in health compared to sleep problems alon...

journal_title：Scientific reports

authors： Stickley A,Leinsalu M,DeVylder JE,Inoue Y,Koyanagi A

更新日期：2019-08-19 00:00:00

abstract：:Geriatric trauma is a major socio-economic problem, especially among the aging Japanese society. Geriatric people are more vulnerable to trauma than younger people; thus, their outcomes are often severe. This study evaluates the characteristics of geriatric trauma divided by age in the Japanese population. We evaluate...

journal_title：Scientific reports

authors： Miyoshi Y,Kondo Y,Hirano Y,Ishihara T,Sueyoshi K,Okamoto K,Tanaka H

更新日期：2020-11-05 00:00:00

abstract：:Given that many fundamental questions in neuroscience are still open, it seems pertinent to explore whether the brain might use other physical modalities than the ones that have been discovered so far. In particular it is well established that neurons can emit photons, which prompts the question whether these biophoto...

journal_title：Scientific reports

authors： Kumar S,Boone K,Tuszyński J,Barclay P,Simon C

更新日期：2016-11-07 00:00:00

abstract：:Bioprosthetic valves for tricuspid valve replacement (TVR) have become increasingly popular in recent years, but mechanical valves remain valuable, particularly for the patients who want to avoid reoperation for bioprostheses malfunction. The aim of this study was to review our 10-year experience in adult patients who...

journal_title：Scientific reports

authors： Zhu X,Luo Y,Zhang E,An Q,Xiao X,Dong L,Guo Y,Dian K,Wu Z

更新日期：2018-11-09 00:00:00

abstract：:The number of magnetoelectric multiferroic materials reported to date is scarce, as magnetic structures that break inversion symmetry and induce an improper ferroelectric polarization typically arise through subtle competition between different magnetic interactions. The (NH4)2[FeCl5(H2O)] compound is a rare case wher...

journal_title：Scientific reports

authors： Alberto Rodríguez-Velamazán J,Fabelo Ó,Millán Á,Campo J,Johnson RD,Chapon L

更新日期：2015-09-29 00:00:00

abstract：:Crypt neurons are a third type of olfactory receptor neurons with a highly unusual "one cell type--one receptor" mode of expression, the same receptor being expressed by the entire population of crypt neurons. Attempts to identify the target region(s) of crypt neurons have been inconclusive so far. We report that TrkA...

journal_title：Scientific reports

authors： Ahuja G,Ivandic I,Saltürk M,Oka Y,Nadler W,Korsching SI

更新日期：2013-01-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Wallisch C,Heinze G,Rinner C,Mundigler G,Winkelmayer WC,Dunkler D

更新日期：2020-06-26 00:00:00

abstract：:α-Dystroglycanopathy (α-DGP) is a group of muscular dystrophy characterized by abnormal glycosylation of α-dystroglycan (α-DG), including Fukuyama congenital muscular dystrophy (FCMD), muscle-eye-brain disease, Walker-Warburg syndrome, and congenital muscular dystrophy type 1D (MDC1D), etc. LARGE, the causative gene f...

journal_title：Scientific reports

authors： Ohtsuka Y,Kanagawa M,Yu CC,Ito C,Chiyo T,Kobayashi K,Okada T,Takeda S,Toda T

更新日期：2015-02-09 00:00:00

abstract：:Extracellular vesicles are selectively enriched in RNA that has potential as disease biomarkers. To systemically characterize circulating extracellular RNA (exRNA) profiles, we performed RNA sequencing analysis on plasma extracellular vesicles derived from 50 healthy individuals and 142 cancer patients. Of ~12.6 milli...

journal_title：Scientific reports

authors： Yuan T,Huang X,Woodcock M,Du M,Dittmar R,Wang Y,Tsai S,Kohli M,Boardman L,Patel T,Wang L

更新日期：2016-01-20 00:00:00

abstract：:In this paper, a new strategy is reported for preparing a label-free β-trophin electrochemiluminescent (ECL) immunosensor with good specificity, reproducibility and stability. An aquagel polymer from the hydrolysis of (3-aminopropyl) trimethoxysilane acted as the linker to catch the Au nanoparticles (AuNPs) on the ind...

journal_title：Scientific reports

authors： Zheng L,Fang C,Yan J,Li H,Tu Y

更新日期：2017-09-11 00:00:00

abstract：:Studies reveal that there exists much interaction and communication between bacterial cells, with parts of these social behaviors depending on cell-cell contacts. The cell-cell contact has proved to be crucial for determining various biochemical processes. However, for cell culture with relatively low cell concentrati...

journal_title：Scientific reports

authors： Xin H,Zhang Y,Lei H,Li Y,Zhang H,Li B

更新日期：2013-01-01 00:00:00

abstract：:The 8th edition of TNM staging system has been released and it incorporates many changes to the T and N classifications for pancreatic cancer. Comparative study between the 7th and 8th edition of TNM staging system from Asian population has not been reported yet. This study aimed to compare the 7th and 8th edition of ...

journal_title：Scientific reports

authors： Cong L,Liu Q,Zhang R,Cui M,Zhang X,Gao X,Guo J,Dai M,Zhang T,Liao Q,Zhao Y

更新日期：2018-07-10 00:00:00

abstract：:Electric double-layer capacitors (EDLCs) or supercapacitors (SCs) are fast energy storage devices with high pulse efficiency and superior cyclability, which makes them useful in various applications including electronics, vehicles and grids. Aqueous SCs are considered to be more environmentally friendly than those bas...

journal_title：Scientific reports

authors： Blomquist N,Wells T,Andres B,Bäckström J,Forsberg S,Olin H

更新日期：2017-01-05 00:00:00

abstract：:Network robustness represents the ability of networks to withstand failures and perturbations. In social networks, maintenance of individual activities, also called persistence, is significant towards understanding robustness. Previous works usually consider persistence on pre-generated network structures; while in so...

journal_title：Scientific reports

authors： Jin X,Jin C,Huang J,Min Y

更新日期：2017-02-21 00:00:00

abstract：:Humans are host to a multitude of microorganisms that rapidly populate the body at birth, subject to a complex interplay that is dependent on host genetics, lifestyle, and environment. The host-associated microbiome, including the oral microbiome, presents itself in a complex ecosystem important to health and disease....

journal_title：Scientific reports

authors： Freire M,Moustafa A,Harkins DM,Torralba MG,Zhang Y,Leong P,Saffery R,Bockmann M,Kuelbs C,Hughes T,Craig JM,Nelson KE

更新日期：2020-05-14 00:00:00

abstract：:Antibody humanization is a key step in the preclinical phase of the development of therapeutic antibodies, originally developed and tested in non-human models (most typically, in mouse). The standard technique of Complementarity-Determining Regions (CDR) grafting into human Framework Regions of germline sequences has ...

journal_title：Scientific reports

authors： Clavero-Álvarez A,Di Mambro T,Perez-Gaviro S,Magnani M,Bruscolini P

更新日期：2018-10-04 00:00:00

abstract：:Circularly polarized laser sources with small footprints and high efficiencies can possess advanced functionalities in optical communication and biophotonic integrated systems. However, the conventional lasers with additional circular-polarization converters are bulky and hardly compatible with nanophotonic circuits, ...

journal_title：Scientific reports

authors： Liao WC,Liao SW,Chen KJ,Hsiao YH,Chang SW,Kuo HC,Shih MH

更新日期：2016-05-25 00:00:00

abstract：:The host mechanisms involved in Escherichia coli O157 super-shedding in cattle is largely unknown. In this study, the comparison of transcriptomes of intestinal tissues between super-shedders (SS) and cattle negative for E. coli O157 (NS) was performed, aiming to identify genes that are potentially associated with sup...

journal_title：Scientific reports

authors： Wang O,McAllister TA,Plastow G,Stanford K,Selinger B,Guan LL

更新日期：2017-08-09 00:00:00

abstract：:Infants' sensitivity to selectively attend to human speech and to process it in a unique way has been widely reported in the past. However, in order to successfully acquire language, one should also understand that speech is a referential, and that words can stand for other entities in the world. While there has been ...

journal_title：Scientific reports

authors： Marno H,Farroni T,Vidal Dos Santos Y,Ekramnia M,Nespor M,Mehler J

更新日期：2015-09-01 00:00:00

abstract：:The bacterial second messenger cyclic di-3',5'-guanosine monophosphate (c-di-GMP) is a key regulator of bacterial motility and virulence. As high levels of c-di-GMP are associated with the biofilm lifestyle, c-di-GMP hydrolysing phosphodiesterases (PDEs) have been identified as key targets to aid development of novel ...

journal_title：Scientific reports

authors： Bellini D,Horrell S,Hutchin A,Phippen CW,Strange RW,Cai Y,Wagner A,Webb JS,Tews I,Walsh MA

更新日期：2017-02-10 00:00:00

abstract：:Improving the affinity of protein-protein interactions is a challenging problem that is particularly important in the development of antibodies for diagnostic and clinical use. Here, we used structure-based computational methods to optimize the binding affinity of VHNAC1, a single-domain intracellular antibody (intrab...

journal_title：Scientific reports

authors： Mahajan SP,Meksiriporn B,Waraho-Zhmayev D,Weyant KB,Kocer I,Butler DC,Messer A,Escobedo FA,DeLisa MP

更新日期：2018-12-04 00:00:00

abstract：:This study aimed to investigate the predictive efficacy of positron emission tomography/computed tomography (PET/CT) and magnetic resonance imaging (MRI) for the pathological response of advanced breast cancer to neoadjuvant chemotherapy (NAC). The breast PET/MRI image deep learning model was introduced and compared w...

journal_title：Scientific reports

authors： Choi JH,Kim HA,Kim W,Lim I,Lee I,Byun BH,Noh WC,Seong MK,Lee SS,Kim BI,Choi CW,Lim SM,Woo SK

更新日期：2020-12-03 00:00:00

abstract：:The strong electronegativity of O dictates that the ground state of singlet CO has positively charged C and negatively charged O, in agreement with ab initio charge analysis, but in disagreement with the dipole direction. Though this unusual phenomenon has been fairly studied, the study of electrostatic potential (EP)...

journal_title：Scientific reports

authors： Kim H,Doan VD,Cho WJ,Valero R,Aliakbar Tehrani Z,Madridejos JM,Kim KS

更新日期：2015-11-06 00:00:00

abstract：:Herein, we report the synthesis of new PtTe2 multi-crystallite nanoparticles (NPs) in different sizes through an annealing process using new nanostructured Pt-Te organometallic NPs as a single source precursor. This precursor was obtained in a single reaction step using Ph2Te2 and H2PtCl6 and could be successfully siz...

journal_title：Scientific reports

authors： Fernández-Lodeiro J,Rodríguez-Gónzalez B,Novio F,Fernández-Lodeiro A,Ruiz-Molina D,Capelo JL,Santos AAD,Lodeiro C

更新日期：2017-08-29 00:00:00

abstract：:Bimetallic catalysts due to the synergistic effects often outperform their single-component counterparts while exhibiting structure and composition-dependent enhancement in active sites, thereby having the potential to improve the current density and over-potential parameters in the water oxidation reaction. Herein, w...

journal_title：Scientific reports

authors： Ehsan MA,Hakeem AS,Rehman A

更新日期：2020-09-02 00:00:00

abstract：:Magnetic skyrmions are promising candidates for the next generation of spintronic devices due to their small size and topologically protected structure. One challenge for using these magnetic states in applications lies on controlling the nucleation process and stabilization that usually requires an external force. He...

journal_title：Scientific reports

authors： Brandão J,Dugato DA,Seeger RL,Denardin JC,Mori TJA,Cezar JC

更新日期：2019-03-11 00:00:00

abstract：:The main feature of the present numerical model is to explore the behavior of Maxwell nanoliquid moving within two horizontal rotating disks. The disks are stretchable and subjected to a magnetic field in axial direction. The time dependent characteristics of thermal conductivity have been considered to scrutinize the...

journal_title：Scientific reports

authors： Ahmadian A,Bilal M,Khan MA,Asjad MI

更新日期：2020-10-13 00:00:00

abstract：:The relative and combined effects of sleep apnea with diabetes mellitus (DM) on cardiovascular outcomes in patients undergoing coronary artery bypass grafting (CABG) remain unknown. In this secondary analysis of data from the SABOT study, 1007 patients were reclassified into four groups based on their sleep apnea and ...

journal_title：Scientific reports

authors： Aung AT,Koo CY,Tam WW,Chen Z,Kristanto W,Sim HW,Kojodjojo P,Kofidis T,Lee CH

更新日期：2020-12-10 00:00:00

abstract：:Antibiotics contamination in food products is of increasing concern due to their potential threat on human health. Herein solid-phase extraction based on magnetic molecularly imprinted polymers coupled with internal extractive electrospray ionization mass spectrometry (MMIPs-SPE-iEESI-MS) was designed for the quantita...

journal_title：Scientific reports

authors： Zhang H,Kou W,Bibi A,Jia Q,Su R,Chen H,Huang K

更新日期：2017-11-07 00:00:00