Abstract:
BACKGROUND:To ascertain if post-operative drain fluid lipase is superior to amylase in routinely detecting clinically significant post-operative pancreatic fistulae (POPF). METHOD:Between January 2015 and March 2016 data were collected on all patients undergoing pancreatic surgery at a regional referral centre. Routine drain fluid analysis was performed on post-operative patients as part of a locally defined enhanced recovery protocol. POPF was diagnosed in accordance with the recently updated International Study Group of Pancreatic Surgery guidance. RESULTS:During the study period, there were 68 pancreatic resections. The median age was 69.1 years. A total of 11 (15.9%) patients developed clinically significant POPF (nine type B and two type C). The median drain amylase result in patients with type B or C leak was 532 IU/L (interquartile range (IQR) 264-833). This was significantly higher than those without a clinical fistula (median 38, IQR 15-376, P = 0.012). The median drain lipase result was 1504 IU/L (IQR 746-2236). This was significantly higher than those without a clinical fistula (median 57, IQR 13-1277, P = 0.012). Fluid amylase had a sensitivity of 81.8% and specificity of 69.2%; fluid lipase had a sensitivity of 91% and specificity of 64.9%. CONCLUSION:Our experience suggests drain fluid amylase or lipase results are not sufficiently sensitive or specific to reassure clinicians and rule out clinically significant POPF. However, if biochemical tests are used to aid decision-making, then lipase is a more sensitive biochemical marker than amylase for the routine detection of clinically significant POPF.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Griffith D,Hanna T,Wong K,Reece-Smith A,Aroori S,Bowles M,Stell D,Briggs Cdoi
10.1111/ans.14266subject
Has Abstractpub_date
2018-06-07 00:00:00eissn
1445-1433issn
1445-2197pub_type
杂志文章abstract:BACKGROUND:Patients taking warfarin are often given interim anticoagulation in the perioperative period. Institutional guidelines that use low-molecular-weight heparin (LMWH) 'bridging' while the international normalized ratio (INR) is sub-therapeutic are often based on the American College of Chest Physicians Anticoag...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12070
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Sacral neuromodulation (SNM) has emerged as a treatment option for faecal incontinence (FI). However, its objective effect on symptoms and anorectal function is inconsistently described. This study aimed to systematically review the impact of SNM on clinical symptoms and gastrointestinal physiology in patien...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13257
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The effect of pneumoperitoneum on veins of the lower limbs related to the intra-abdominal working pressures during laparoscopic cholecystectomy has not been thoroughly investigated. We tested the hypothesis that working pressures do not affect the venous haemodynamics in the lower limbs. METHODS:The cross-s...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03906.x
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Malignant blue nevus, blue nevus-associated melanoma and blue nevus-like melanoma are all terms used to describe malignant melanomas arising from, in association with, or resembling blue nevi. This review is aimed at summarizing the available literature to reduce the confusion surrounding this rare malignanc...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13946
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to investigate the effect of N-acetylcysteine on intestinal reperfusion injury. METHODS:Forty Sprague-Dawley rats were divided into four groups (n = 10): sham, sham + N-acetylcysteine, reperfusion, and reperfusion + N-acetylcysteine. Thirty minutes of ischaemia +/- 30 min of...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03111.x
更新日期:2004-08-01 00:00:00
abstract::Abdominal Compartment Syndrome (ACS) is an increasingly recognized syndrome of intra-abdominal hypertension and generalized physiological dysfunction in critically ill patients. Patients suffering a ruptured abdominal aortic aneurysm (rAAA) are at risk of developing ACS. The objective of the study was to compare the c...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04466.x
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:We describe a technique of U-shaped bulboprostatic anastomosis for urethral injury after pelvic trauma. METHODS:Sixty-eight male patients were included in our study. Suprapubic cystostomy was carried out initially, followed by U-shaped prostatobulbar anastomosis after 6-12 weeks. Follow ups were carried out...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04584.x
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Incidence of the gastro-oesophageal junction adenocarcinoma is increasing. Siewert's classification subdivides junctional adenocarcinomas anatomically. Cytokeratin (CK) 7 and 20 immunophenotypes differentiate Barrett's intestinal metaplasia (IM) from gastric IM. Comparing CK immunostaining with Siewert's cla...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04147.x
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Evidence suggests that there is considerable variation in the types of procedures used to treat cancer. This variation may result in suboptimal or cost-ineffective care. The present study examined the variation in surgical treatment of melanoma before the establishment of a Melanoma Network that could promot...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03717.x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:There is evidence that antibiotics can be used as primary treatment for appendicitis, however, delayed surgical treatment might still be associated with perforation. Most patients at risk of perforation have high Alvarado scores. We designed a protocol-based approach to suspected appendicitis, in which the A...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.02993.x
更新日期:2004-05-01 00:00:00
abstract::Although the published work in health care increasingly promotes aviation as a high-reliability industry to be emulated, there is little empirical research to justify equating the dynamics of health care's operating environment with that of aviation. This article examines some of the potential key areas of difference ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04619.x
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Pathological complete response following neoadjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer is associated with reduced local recurrence and improved long-term outcome. However, the prognostic value of a partial response, or of tumour regression in patients with metastatic disease, is less...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13394
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Chlorhexidine (CHL) has antiseptic and disinfectant properties used to prevent hospital-acquired infections. CHL-induced anaphylaxis is poorly reported in surgical literature despite government warnings and growing recognition. The aim of this review is to increase awareness of CHL-induced anaphylaxis in the...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13269
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The Consolidated Standards of Reporting Trials (CONSORT) Statement outlines acceptable ways of performing and reporting clinical trials. The objective of the present study was to identify evolving patterns in the methodological standards of surgical trials. METHODS:Compliance with 12 key standards from the ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03554.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:For proven gastro-oesophageal reflux disease, partial fundoplication is considered as effective as Nissen, but with fewer side effects. The aim of this meta-analysis was to compare the effect of laparoscopic partial fundoplication (LPF) with laparoscopic Nissen fundoplication (LNF). METHODS:Extensive medica...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,meta分析
doi:10.1111/j.1445-2197.2010.05637.x
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Patients fulfilling Amsterdam-1 criteria without mismatch repair deficiency (termed familial colorectal cancer type X (FCC type X)) were reported to have lower cancer risks than classic Lynch syndrome. This study investigates the polyp and cancer burden of this population and demonstrates relationships with ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2010.05606.x
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Neoadjuvant therapy, radical lymphadenectomy and treatment in high-volume centres have been proposed to improve outcomes for resectable oesophageal tumours. The aim of the present study was to review the oesophagectomy experience of a single surgeon with a moderate caseload who uses neoadjuvant therapy selec...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.04855.x
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:We aimed to document the anatomical variations of pulmonary fissures found during routine forensic autopsies. METHODS:A total of 256 pairs of lungs were investigated. Presence of any variant and accessory fissures was noted. RESULTS:Seventy-seven percent of the lungs had anatomical variations. In about 2/3...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15553
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to determine the anastomotic leak rate for colorectal cancer resections in patients with metastases (compared to those without), and to determine the impact of anastomotic leaks on survival. METHODS:This is a retrospective analysis of all patients who underwent resection and pr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14494
更新日期:2018-09-01 00:00:00
abstract::Pancreaticobiliary reflux may occur either as a result of an anatomically abnormal pancreaticobiliary junction or because of a functionally impaired sphincter despite a normal radiological appearance. It is associated with a wide spectrum of biliary diseases, including gall bladder and bile duct carcinoma. Pancreatico...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2012.06076.x
更新日期:2012-06-01 00:00:00
abstract::Achalasia is a motility disorder encountered by surgeons during the investigation and treatment of dysphagia. Recent advances in manometry technology, a widely accepted new classification system and a new treatment rapidly gaining international acceptance, have changed the working knowledge required to successfully ma...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13497
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The recurrence rate following stripping of the long saphenous vein is unacceptable. Repair of the terminal valve of the long saphenous vein is a physiological alternative. The aim of the present study was to prospectively compare the long-term recurrence rates in patients having had reparative and ablative p...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.02714.x
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Anastomotic dehiscence (AD) is the most feared complication following colonic and rectal anastomosis. Multiple attempts have been made to correlate the levels of biomarkers to the risk of AD. This study attempts to compare C-reactive protein (CRP), procalcitonin (PCT) and neutrophil-to-lymphocyte ratio (NLR)...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14369
更新日期:2018-01-27 00:00:00
abstract::Constipation is very common in all age groups and can be resistant to standard therapies, producing chronic morbidity. Childhood onset constipation frequently produces symptoms that persist into adulthood. Recent advances have been made in the diagnosis and treatment of childhood constipation that could have applicati...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-1433.2004.03149.x
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Surgical approach into the fissural parenchyma may be an important and modifiable factor for the prevention of air leak after anatomical lung resections. Fissureless fissure-last technique has been described as useful technique to reduce air leak, yet in video-assisted thoracoscopic surgery (VATS) data are l...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13884
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:The role of minimally invasive major hepatectomy (MIMH) remains controversial and questions remain about its safety and reproducibility outside expert centres. This study examines the changing trends, safety and outcomes associated with the adoption of MIMH based on a contemporary single institution experien...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15563
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Hepatic haemangiomas are congenital vascular malformations. They are the most common benign tumours of the liver and are often asymptomatic. Spontaneous or traumatic rupture, intratumoral bleeding, consumption coagulopathy and rapid growth are the mandatory surgical indications. We present our experience ove...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03869.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Despite conflicting data regarding oncological outcomes, studies demonstrate that complete mesocolic excision (CME) and central vascular ligation (CVL) for right-sided colon cancer removes significantly more tissue and yields higher lymph node counts when compared to conventional resection. This study aims t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16224
更新日期:2020-08-11 00:00:00
abstract:BACKGROUND:Up to 20% of patients are dissatisfied after total knee arthroplasty (TKA). There are many contributing factors. The relationship between preoperative osteoarthritis (OA) severity and outcome post TKA remains unclear. This review explores the relationship between preoperative OA severity with patient reporte...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15343
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Most large-volume centres use left heart bypass (LHB) as their preferred organ protection strategy during repair of descending thoracic aortic (DTA) and thoracoabdominal aortic (TAA) pathologies. We investigate the use of hypothermic circulatory arrest (HCA) for similar pathologies and compare the outcomes o...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.16287
更新日期:2020-12-01 00:00:00