Abstract:
BACKGROUND:The aim of the present study was to investigate the effect of N-acetylcysteine on intestinal reperfusion injury. METHODS:Forty Sprague-Dawley rats were divided into four groups (n = 10): sham, sham + N-acetylcysteine, reperfusion, and reperfusion + N-acetylcysteine. Thirty minutes of ischaemia +/- 30 min of reperfusion was performed under 100 mg/kg N-acetylcysteine or placebo, administered 30 min before the operation in the groups where appropriate. Ileum samples were resected for histopathologic evaluation and tissue malondialdehyde and super oxide dismutase level determination. RESULTS:The mean mucosal injury score and malondialdehyde level of the reperfusion and reperfusion + N-acetylcysteine groups were significantly higher than that of the control and control + N-acetylcysteine group (P < 0.01, P < 0.05, respectively). Mean super oxide dismutase level of the control + N-acetylcysteine group was significantly higher than that of the other groups (P < 0.05). CONCLUSION:N-Acetylcysteine did not prevent intestinal reperfusion injury by means of histopathologic findings and malondialdehyde level.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Hazinedaroglu SM,Dulger F,Kayaoglu HA,Pehlivan M,Serinsoz E,Canbolat O,Erverdi Ndoi
10.1111/j.1445-1433.2004.03111.xkeywords:
subject
Has Abstractpub_date
2004-08-01 00:00:00pages
676-8issue
8eissn
1445-1433issn
1445-2197pii
ANS3111journal_volume
74pub_type
杂志文章abstract:BACKGROUND:The 'obesity epidemic' is expected to result in an increased incidence of knee osteoarthritis and hence total knee replacements (TKRs). Reviews have demonstrated the conflicting results of TKR for all obese (body mass index (BMI) >30). The aim of this literature review was to specifically evaluate outcomes o...
journal_title:ANZ journal of surgery
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更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Patients with centrally located tumours involving the nipple-areolar complex (NAC) who undergo breast-conserving treatment (BCT) are at high risk for breast deformity and asymmetry. Immediate oncoplastic breast reconstruction (OBR) can have a favourable impact on surgical outcome. METHODS:We retrospectively...
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abstract:BACKGROUND:Stabbing and firearm trauma causing severe injuries (injury severity score (ISS) >15) and death is uncommon in Australia. The present study describes the experience with stabbings and firearm trauma causing severe injuries at a major Australian urban trauma centre. METHODS:Data from a prospectively generate...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03333.x
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abstract:BACKGROUND: The purpose of credentialing is to ensure that clinicians provide safe, high-quality health-care services in accordance with good practice and legal requirements. This review assessed the institutional credentialing processes and governance structures required to support credentialing processes at an insti...
journal_title:ANZ journal of surgery
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abstract:BACKGROUND:In Australia, there has been a shift from the traditional 'on-call' surgical model to the 'acute surgical unit' (ASU) model to improve outcomes in acute general surgery. Using emergency appendicectomy as a standardized procedure, we aimed to identify the different patterns of care between these on-call struc...
journal_title:ANZ journal of surgery
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abstract:BACKGROUND:The isolated limb infusion (ILI) technique is a simpler and less invasive alternative to isolated limb perfusion, which allows regional administration of high-dose chemotherapy to patients with advanced melanoma and other malignancies restricted to a limb. METHODS:Patients from two institutions, treated by ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,多中心研究
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更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Patent Blue V dye (PBVD) can cause severe anaphylaxis. For sentinel node biopsy (SNB) in breast cancer patients, controversy exists as to the utility of PBVD in addition to lymphoscintigraphy. This survey assessed Australian and New Zealand breast surgeons' experience of anaphylaxis with PBVD. METHODS:The s...
journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2007-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2016-09-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:The Victorian Audit of Surgical Mortality (VASM) seeks to peer review all deaths associated with surgical care in Victoria, Australia. The effectiveness of the VASM as an educational and quality improvement tool is dependent on the accuracy of source data it receives. We aimed to examine the accuracy and qua...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-09-01 00:00:00
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2018-09-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2005-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00
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更新日期:2020-07-01 00:00:00
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journal_title:ANZ journal of surgery
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更新日期:2002-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2007-01-01 00:00:00