N-acetylcysteine in intestinal reperfusion injury: an experimental study in rats.

Abstract:

BACKGROUND:The aim of the present study was to investigate the effect of N-acetylcysteine on intestinal reperfusion injury. METHODS:Forty Sprague-Dawley rats were divided into four groups (n = 10): sham, sham + N-acetylcysteine, reperfusion, and reperfusion + N-acetylcysteine. Thirty minutes of ischaemia +/- 30 min of reperfusion was performed under 100 mg/kg N-acetylcysteine or placebo, administered 30 min before the operation in the groups where appropriate. Ileum samples were resected for histopathologic evaluation and tissue malondialdehyde and super oxide dismutase level determination. RESULTS:The mean mucosal injury score and malondialdehyde level of the reperfusion and reperfusion + N-acetylcysteine groups were significantly higher than that of the control and control + N-acetylcysteine group (P < 0.01, P < 0.05, respectively). Mean super oxide dismutase level of the control + N-acetylcysteine group was significantly higher than that of the other groups (P < 0.05). CONCLUSION:N-Acetylcysteine did not prevent intestinal reperfusion injury by means of histopathologic findings and malondialdehyde level.

journal_name

ANZ J Surg

journal_title

ANZ journal of surgery

authors

Hazinedaroglu SM,Dulger F,Kayaoglu HA,Pehlivan M,Serinsoz E,Canbolat O,Erverdi N

doi

10.1111/j.1445-1433.2004.03111.x

keywords:

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

676-8

issue

8

eissn

1445-1433

issn

1445-2197

pii

ANS3111

journal_volume

74

pub_type

杂志文章
  • Total knee replacement in the morbidly obese: a literature review.

    abstract:BACKGROUND:The 'obesity epidemic' is expected to result in an increased incidence of knee osteoarthritis and hence total knee replacements (TKRs). Reviews have demonstrated the conflicting results of TKR for all obese (body mass index (BMI) >30). The aim of this literature review was to specifically evaluate outcomes o...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-2197.2010.05396.x

    authors: Samson AJ,Mercer GE,Campbell DG

    更新日期:2010-09-01 00:00:00

  • Oncoplastic partial breast reconstruction improves patient satisfaction and aesthetic outcome for central breast tumours.

    abstract:BACKGROUND:Patients with centrally located tumours involving the nipple-areolar complex (NAC) who undergo breast-conserving treatment (BCT) are at high risk for breast deformity and asymmetry. Immediate oncoplastic breast reconstruction (OBR) can have a favourable impact on surgical outcome. METHODS:We retrospectively...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.15078

    authors: Shechter S,Friedman O,Inbal A,Arad E,Menes T,Barsuk D,Gur E,Barnea Y

    更新日期:2019-05-01 00:00:00

  • Single-institution review of managing dermatofibrosarcoma protuberans.

    abstract:BACKGROUND:Dermatofibrosarcoma protuberans (DFSP) is a rare locally advanced soft-tissue tumour that is often misdiagnosed at presentation, resulting in inadequate initial resection, requiring multiple resections and reconstructive procedures. We reviewed our experience and treatment outcomes with this tumour and propo...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13276

    authors: Tan YG,Chia CS,Loh WL,Teo MC

    更新日期:2016-05-01 00:00:00

  • Severe trauma caused by stabbing and firearms in metropolitan Sydney, New South Wales, Australia.

    abstract:BACKGROUND:Stabbing and firearm trauma causing severe injuries (injury severity score (ISS) >15) and death is uncommon in Australia. The present study describes the experience with stabbings and firearm trauma causing severe injuries at a major Australian urban trauma centre. METHODS:Data from a prospectively generate...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2005.03333.x

    authors: Wong K,Petchell J

    更新日期:2005-04-01 00:00:00

  • Credentialing of surgeons: a systematic review across a number of jurisdictions.

    abstract:BACKGROUND:  The purpose of credentialing is to ensure that clinicians provide safe, high-quality health-care services in accordance with good practice and legal requirements. This review assessed the institutional credentialing processes and governance structures required to support credentialing processes at an insti...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-2197.2012.06115.x

    authors: Gurgacz SL,Smith JA,Truskett PG,Babidge WJ,Maddern GJ

    更新日期:2012-07-01 00:00:00

  • Haemorrhagic complications of pancreaticoduodenectomy.

    abstract:BACKGROUND:Haemorrhagic complication occurs in 5-16% of patients following pancreaticoduodenectomy (PD). We report an analysis of patients with post-PD bleed, to identify predictors of bleed, predictors of survival following bleed and the management of post-PD bleed. METHODS:Two hundred and eighteen patients with peri...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-1433.2004.03212.x

    authors: Balachandran P,Sikora SS,Raghavendra Rao RV,Kumar A,Saxena R,Kapoor VK

    更新日期:2004-11-01 00:00:00

  • Comparative analysis of emergency general surgery on-call structure and its impact on emergency appendicectomy outcomes.

    abstract:BACKGROUND:In Australia, there has been a shift from the traditional 'on-call' surgical model to the 'acute surgical unit' (ASU) model to improve outcomes in acute general surgery. Using emergency appendicectomy as a standardized procedure, we aimed to identify the different patterns of care between these on-call struc...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.16558

    authors: Gounder J,Dissanayake B,Burstow MJ,Yuide PJ,Naidu S,Lancashire RP,Chua TC

    更新日期:2021-01-18 00:00:00

  • Isolated limb infusion with hyperthermia and chemotherapy for advanced limb malignancy: factors influencing toxicity.

    abstract:BACKGROUND:The isolated limb infusion (ILI) technique is a simpler and less invasive alternative to isolated limb perfusion, which allows regional administration of high-dose chemotherapy to patients with advanced melanoma and other malignancies restricted to a limb. METHODS:Patients from two institutions, treated by ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1445-2197.2012.06249.x

    authors: Duprat Neto JP,Mauro AC,Molina AS,Nishinari K,Zurstrassen CE,Costa OF,Belfort FA,Facure L,Fregnani JH

    更新日期:2014-09-01 00:00:00

  • Patent Blue V dye anaphylaxis: experience of Australian and New Zealand surgeons.

    abstract:BACKGROUND:Patent Blue V dye (PBVD) can cause severe anaphylaxis. For sentinel node biopsy (SNB) in breast cancer patients, controversy exists as to the utility of PBVD in addition to lymphoscintigraphy. This survey assessed Australian and New Zealand breast surgeons' experience of anaphylaxis with PBVD. METHODS:The s...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2012.06277.x

    authors: Wong A,Spillane A,Breast Surgeons of Australia and New Zealand Incorporated (BreastSurgANZ).

    更新日期:2014-01-01 00:00:00

  • Modified elliptical rotation flap for sacrococcygeal pilonidal sinus disease.

    abstract:BACKGROUND:Although various surgical procedures have been described for pilonidal sinus disease, the best surgical technique is still controversial. The aim of this study was to evaluate the short-term results of modified elliptical rotation flap (MERF) for pilonidal sinus disease in terms of post-operative complicatio...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12818

    authors: Dizen H,Yoldas Ö,Yıldız M,Cilekar M,Dilektaşlı E

    更新日期:2014-10-01 00:00:00

  • Developmental anomaly of the inferior vena cava.

    abstract::Despite the many possible modes of presentation, congenital anomalies of the inferior vena cava are increasingly being found in asymptomatic patients. Although plain chest radiography may reveal enough suggestive signs, the diagnosis is usually confirmed by ultrasound, computed tomography and magnetic resonance imagin...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1445-2197.2003.02502.x

    authors: Sandercoe GD,Brooke-Cowden GL

    更新日期:2003-05-01 00:00:00

  • Preoperative beta-blocker use reduces atrial fibrillation in off-pump coronary bypass surgery.

    abstract:BACKGROUND:Atrial fibrillation (AF) after coronary artery bypass graft surgery constitutes the most common sustained arrhythmia and results in many complications. The purpose of this study was to assess the effects of prophylactic use of beta-blockers against atrial fibrillation in off-pump surgery patients in the earl...

    journal_title:ANZ journal of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1445-2197.2007.04088.x

    authors: Imren Y,Benson AA,Zor H,Tasoglu I,Ereren E,Sinci V,Gokgoz L,Halit V

    更新日期:2007-06-01 00:00:00

  • Recovery of parathyroid function after total thyroidectomy: long-term follow-up study.

    abstract:BACKGROUND:To prevent postoperative hypoparathyroidism following total thyroidectomy, the parathyroid glands are preserved in situ and/or resected or devascularized parathyroid glands are autotransplanted. A retrospective investigation was conducted utilizing biochemical and specific endocrine assessments to evaluate t...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2005.03435.x

    authors: Kihara M,Miyauchi A,Kontani K,Yamauchi A,Yokomise H

    更新日期:2005-07-01 00:00:00

  • Multiple interventions with prolonged length of stay are required for treatment of necrotizing pancreatitis.

    abstract:BACKGROUND:A proportion of patients with acute pancreatitis (AP) develop necrosis. Around a third will become infected, and this is associated with a significant requirement for intervention and support. We evaluated the burden of necrotizing pancreatitis (NP) in an Australian tertiary hospital with regards to morbidit...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13883

    authors: Shilton H,Breen D,Gupta S,Evans P,Pilgrim C

    更新日期:2018-03-01 00:00:00

  • Refinements and restoring contour in head and neck reconstruction.

    abstract:BACKGROUND:To date head and neck reconstructions of oncological defects have concentrated on primarily filling the defect to achieve primary wound healing, secondly restore function and lastly cosmesis. This paper describes a refinement of existing free tissue transfer techniques for improvement of contour, function an...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ans.13061

    authors: Sofiadellis F,Grinsell D

    更新日期:2016-09-01 00:00:00

  • The learning curve in learning the curve: a review of Nuss procedure in teenagers.

    abstract:BACKGROUND:The Nuss procedure is a new minimally invasive repair for pectus excavatum that was first published in 1998. Modifications in technique are constantly evolving to minimize complications, especially bar displacement, which are higher in adolescents and adults. The present study reviews our early experience wi...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2005.03402.x

    authors: Ong CC,Choo K,Morreau P,Auldist A

    更新日期:2005-06-01 00:00:00

  • Validation of data submitted by the treating surgeon in the Victorian Audit of Surgical Mortality.

    abstract:BACKGROUND:The Victorian Audit of Surgical Mortality (VASM) seeks to peer review all deaths associated with surgical care in Victoria, Australia. The effectiveness of the VASM as an educational and quality improvement tool is dependent on the accuracy of source data it receives. We aimed to examine the accuracy and qua...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14910

    authors: Hansen D,Hansen E,Retegan C,Morphet J,Beiles CB

    更新日期:2019-01-01 00:00:00

  • Delivery of surgical care in Samoa: perspectives on capacity, barriers and opportunities by local providers.

    abstract:BACKGROUND:The Pacific Island nation of Samoa faces a number of challenges in delivering surgical care. Our group aimed to identify the barriers and opportunities to improving the delivery of safe, affordable, timely surgical care in Samoa. METHODS:A mixed-methods approach was undertaken. The quantitative analysis use...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.15295

    authors: Comery B,Perry WRG,Young S,Dare A,Matalavea B,Bissett IP,Windsor JA

    更新日期:2019-06-18 00:00:00

  • Paediatric appendicitis: increased disease severity and complication rates in rural children.

    abstract:BACKGROUND:Appendicitis is the most common surgical emergency affecting children. Rurality has been shown to be a predictor of worse surgical outcomes in patients with acute appendicitis compared to urban residents. There are no previously published studies investigating this in Australasia. METHODS:A 10-year retrospe...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.15328

    authors: Elliott BM,Witcomb Cahill H,Harmston C

    更新日期:2019-09-01 00:00:00

  • Laparoscopic revision of gastric band surgery.

    abstract:AIM:To identify the outcome of laparoscopic revision of gastric band surgery with respect to percentage of excess weight lost (%EWL). METHODS:Analysis of a prospective database was then performed and %EWL was plotted with respect to time from initial procedure and also time from revision procedure. RESULTS:All revisi...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2009.05088.x

    authors: Bardsley S,Hopkins G

    更新日期:2010-05-01 00:00:00

  • Hartmann's reversal: a comparative study between laparoscopic and open approaches.

    abstract:BACKGROUND:A reversal of Hartmann's procedure can be performed using either a laparoscopic or open approach. However, laparoscopic reversal (LR) of Hartmann's procedure is challenging. This study was designed to compare the results between open and laparoscopic approaches. METHODS:This was a retrospective study of pro...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13979

    authors: Kwak HD,Kim J,Kang DW,Baek SJ,Kwak JM,Kim SH

    更新日期:2018-05-01 00:00:00

  • Laparoscopic versus robotic-assisted radical prostatectomy: an Australian single-surgeon series.

    abstract:BACKGROUND:In Australia, robotic-assisted radical prostatectomy (RARP) has steadily replaced open and laparoscopic surgery in the management of localized prostate cancer. Given the increased cost of this technology, we aimed to compare the perioperative, pathological, oncological and functional outcomes as well as shor...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12602

    authors: Papachristos A,Basto M,Te Marvelde L,Moon D

    更新日期:2015-03-01 00:00:00

  • Anastomotic leaks in stage IV colorectal cancer.

    abstract:BACKGROUND:The purpose of this study was to determine the anastomotic leak rate for colorectal cancer resections in patients with metastases (compared to those without), and to determine the impact of anastomotic leaks on survival. METHODS:This is a retrospective analysis of all patients who underwent resection and pr...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14494

    authors: Ng SC,Stupart D,Bartolo D,Watters D

    更新日期:2018-09-01 00:00:00

  • Evaluation of fresh frozen plasma usage at a tertiary care hospital in North India.

    abstract:BACKGROUND:Concerns regarding transfusion-transmitted infections and non-availability of blood components in developing nations, make it crucial to optimize fresh frozen plasma (FFP) transfusions and reduce wastage. METHODS:A concurrent prospective study of FFP usage was carried out in a tertiary care hospital in nort...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2005.03422.x

    authors: Chaudhary R,Singh H,Verma A,Ray V

    更新日期:2005-07-01 00:00:00

  • Elevations of serum CA-125 predict severity of acute appendicitis in males.

    abstract:BACKGROUND:Acute appendicitis (AA) is a common indication for urgent abdominal surgery. CA-125 glycoprotein antigen is a non-specific marker for epithelial ovarian cancer; CA-125 serum levels also increased in the conditions of peritoneal inflammation. The aim of this study was to examine the correlation between serum ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13128

    authors: Berger Y,Nevler A,Shwaartz C,Lahat E,Zmora O,Gutman M,Shabtai M

    更新日期:2016-04-01 00:00:00

  • Endovascular grafting of the thoracic aorta, an evolving therapy: ten-year experience in a single centre.

    abstract:BACKGROUND:Surgical therapy for the thoracic aorta carries a high morbidity and mortality. Endovascular therapy for aneurysms and its adaptation to the thoracic aorta over the past 10 years is an exciting advance. This is a retrospective review of endovascular grafting of the thoracic aorta during the past decade at Ro...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2007.04293.x

    authors: Sandroussi C,Waltham M,Hughes CF,May J,Harris JP,Stephen MS,White GH

    更新日期:2007-11-01 00:00:00

  • Clinical aspects of abdominal actinomycosis: a systematic review.

    abstract:BACKGROUND:Abdominal actinomycosis (AA) is a rare infection. The aim of this study was to summarize the evidence available on AA. METHODS:A systematic review was conducted. Data sources included Trip Database, BIREME, SciELO, Cochrane Library, WoS, MEDLINE, EMBASE, SCOPUS, IBECS and LILACS. Eligibility criteria includ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.16141

    authors: Manterola C,Grande L,Riffo-Campos ÁL,Salgado C,Otzen T

    更新日期:2020-07-01 00:00:00

  • Wound healing and growth factor expression in T lymphocyte deficiency.

    abstract:BACKGROUND:There are many clinical situations in which immune suppression or deficiency occurs. This may lead to healing impairment. The aim of the present study was to characterize the effect of T lymphocyte deficiency on wound healing, and on -platelet-derived growth factor (PDGF), bFGF (basic fibroblast growth facto...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1445-2197.2002.02424.x

    authors: Chircop MP,Yu Y,Berney CR,Yang JL,Crowe PJ,Walsh WR

    更新日期:2002-07-01 00:00:00

  • Long-term venous access insertion: 'the learning curve'.

    abstract:BACKGROUND:The central venous access port device (CVAPD) provides reliable vascular access and is used for delivery of fluids and for obtaining blood samples. However, it can carry some intra- and post-operative complications such as thrombosis, pneumothorax, catheter fracture and port malposition. This article describ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13338

    authors: Fosh B,Canepa M,Eaton M

    更新日期:2016-12-01 00:00:00

  • Flat adenomas.

    abstract::This article was presented at the conjoint CSSA and RACS (colorectal section) spring meeting Queensland, Australia, September 2004. The adenoma-carcinoma sequence describes a succession of events from polypoid adenoma to colorectal cancer. However, this model only accounts for up to two-thirds of colorectal cancers. T...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-2197.2006.03847.x

    authors: Speake D,Biyani D,Frizelle FA,Watson AJ

    更新日期:2007-01-01 00:00:00