Anastomotic leaks in stage IV colorectal cancer.

Abstract:

BACKGROUND:The purpose of this study was to determine the anastomotic leak rate for colorectal cancer resections in patients with metastases (compared to those without), and to determine the impact of anastomotic leaks on survival. METHODS:This is a retrospective analysis of all patients who underwent resection and primary anastomosis for colorectal adenocarcinoma at a single institution between January 2002 and December 2014. RESULTS:A total of 843 patients underwent a resection and primary anastomosis for colorectal adenocarcinoma (661 colon and 182 rectal). Of these, 135 (16%) had metastases and 708 (84%) did not. Anastomotic leaks occurred in 17 of 135 (13%) patients with metastases, and in 37 of 798 (5.2%) patients without metastases (P = 0.003). Peri-operative mortality occurred in 13 of 135 (9.6%) patients with metastases, compared with 19 of 708 (2.7%) patients without metastases (P = 0.0003). Anastomotic leak was associated with a reduction in overall survival (median survival 121 months without anastomotic leak versus 66 months in patients who had an anastomotic leak (P = 0.02)). If the patients who died peri-operatively are excluded from this analysis, however, long-term mortality was similar (125 months versus 101 months; P = 0.70). CONCLUSION:Metastatic disease was associated with an increased risk of anastomotic leak and a higher peri-operative mortality rate after colorectal resections for cancer. Patients with anastomotic leaks had a higher peri-operative mortality rate, but long-term survival was unaffected beyond the peri-operative phase.

journal_name

ANZ J Surg

journal_title

ANZ journal of surgery

authors

Ng SC,Stupart D,Bartolo D,Watters D

doi

10.1111/ans.14494

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

E649-E653

issue

9

eissn

1445-1433

issn

1445-2197

journal_volume

88

pub_type

杂志文章
  • Clinical outcomes and safety of distal biceps repair using a modified entry point.

    abstract:BACKGROUND:The purpose of this study is to determine the safety of a one-incision technique for distal biceps repair with modified repair entry point in regards to the distance from the posterior interosseous nerve (PIN). Secondly, we present the clinical results of patients having undergone this procedure. METHODS:Te...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13684

    authors: Baba M,Leon JV,Symes M,Dorrestijn O,Young A,Cass B

    更新日期:2017-05-01 00:00:00

  • Time to computed tomography scanning for major trauma patients: the Australian reality.

    abstract:BACKGROUND:Computed tomography (CT) can facilitate the diagnosis of life-threatening injuries in polytrauma patients. Reported times to imaging vary widely, but it has been suggested that rapid whole body scanning improves mortality rates. The aim of this study was to determine the time to CT for severe polytrauma pati...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2012.06150.x

    authors: Easton R,Sisak K,Balogh ZJ

    更新日期:2012-09-01 00:00:00

  • Surgical wisdom and Genghis Khan's Pax Mongolica.

    abstract:BACKGROUND:The unrivalled conquests of Genghis Khan (CE c.1162-1227) led to the establishment of the Greater Mongolian Empire. By 1279, the Mongol dynasty controlled a vast Empire which, for the first time in history, unified Europe and China via the famous Silk Road. The ensuing century of peace and stability is refer...

    journal_title:ANZ journal of surgery

    pub_type: 历史文章,杂志文章

    doi:10.1111/ans.13813

    authors: Köstenbauer J

    更新日期:2017-03-01 00:00:00

  • Is bilateral duplex scanning necessary in patients with symptoms of deep venous thrombosis?

    abstract:BACKGROUND:Venous duplex ultrasound scanning (VDUS) has been shown to be an accurate non-invasive means to diagnose symptomatic deep venous thrombosis (DVT). The aim of our study was to determine whether bilateral VDUS is necessary in patients who present with symptoms of DVT. METHODS:We retrospectively reviewed the r...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-1433.2004.03187.x

    authors: Lemech LD,Sandroussi C,Makeham V,Burnett A,Harris JP

    更新日期:2004-10-01 00:00:00

  • Effect of magnesium on arrhythmia incidence in patients undergoing coronary artery bypass grafting.

    abstract:BACKGROUND:Cardiac arrhythmia after coronary artery bypass grafting (CABG) surgery is a common complication of cardiac surgery. The effect of serum magnesium, hypomagnesaemia treatment and prophylactic administration of magnesium in the development and prevention of arrhythmias is controversial and there are many diffe...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ans.14056

    authors: Mohammadzadeh A,Towfighi F,Jafari N

    更新日期:2018-06-01 00:00:00

  • Paul of Aegina's surgical instruments: a complete surgical instrumentarium in the seventh century AD.

    abstract:BACKGROUND:Although current progress in surgical instruments is oriented towards stapler devices, minimally invasive instrumentation and advanced cautery tools, it definitely seems intriguing to determine what instruments were used in antiquity and to appraise their use. Most adequate information can be retrieved from ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13027

    authors: Papadakis M,de Bree E,Trompoukis C,Manios A

    更新日期:2018-07-01 00:00:00

  • Neutrophil-to-lymphocyte ratio predicts anastomotic dehiscence.

    abstract:BACKGROUND:Anastomotic dehiscence (AD) is the most feared complication following colonic and rectal anastomosis. Multiple attempts have been made to correlate the levels of biomarkers to the risk of AD. This study attempts to compare C-reactive protein (CRP), procalcitonin (PCT) and neutrophil-to-lymphocyte ratio (NLR)...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14369

    authors: Walker PA,Kunjuraman B,Bartolo DCC

    更新日期:2018-01-27 00:00:00

  • Tensile strength of surgical knots in abdominal wound closure.

    abstract::Abdominal wound dehiscence is a surgical catastrophe that can be attributed to patients or technical factors. The technical properties of the monofilament sutures and knots that are commonly used in abdominal closure are poorly understood. The aim of this study was to compare the tensile strength of monofilament sutur...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2007.04394.x

    authors: Fong ED,Bartlett AS,Malak S,Anderson IA

    更新日期:2008-03-01 00:00:00

  • Sustaining the surgical educator workforce in Australia and New Zealand.

    abstract:BACKGROUND:The education and training of tomorrow’s surgeons are predicated upon the involvement of a broad spectrum of surgical educators. Identification of the factors that influence their ongoing participation is crucial for its continuity. METHODS:A study was performed on 695 surgeons identified as having major in...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2011.05777.x

    authors: Collins JP,Smith MJ,Lambert T,Hillis DJ

    更新日期:2011-06-01 00:00:00

  • Scatter of orthopaedic research: can orthopods stay up-to-date with research?

    abstract:BACKGROUND:The volume of orthopaedic literature is increasing exponentially, becoming more widely scattered among journals. The rate of increase in orthopaedics is greater than other specialties. We aimed to identify the number of different journals an orthopaedic surgeon would need to read to stay up-to-date with curr...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12902

    authors: Wijenayake L,Conroy S,Turner D,Thorning S,Glasziou P

    更新日期:2015-06-01 00:00:00

  • Ethnic disparities in rates of publicly funded bariatric surgery in New Zealand (2009-2014).

    abstract:BACKGROUND:Publicly funded bariatric surgery in New Zealand (NZ) is steadily on the rise to meet the obesity epidemic. Ethnic disparities in obesity rates exist in NZ with Māori and Pacific people having three to five times higher rates than all other ethnic groups within NZ. Ethnic disparities in rates of bariatric su...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14220

    authors: Rahiri JL,Lauti M,Harwood M,MacCormick AD,Hill AG

    更新日期:2018-05-01 00:00:00

  • Solid pseudopapillary tumour of the pancreas.

    abstract:BACKGROUND:Solid pseudopapillary tumour of the pancreas is a rare pancreatic tumour that occurs predominantly in women, with very few cases reported in men. This is a tumour with low malignancy potential and surgical resection usually results in cure. METHODS:A retrospective review of our experience with solid pseudop...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1445-2197.2003.t01-1-02634.x

    authors: Ng KH,Tan PH,Thng CH,Ooi LL

    更新日期:2003-06-01 00:00:00

  • Patient-related factors influence the risk of developing intestinal stoma complications in early post-operative period.

    abstract:BACKGROUND:Few studies have investigated the risk factors associated with developing intestinal stoma complications using appropriate multivariable methods. We aimed to determine the prevalence of, and risk factors for, stomal complications. METHODS:A retrospective, case-control methodology was used to investigate 12 ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13397

    authors: Harilingam M,Sebastian J,Twum-Barima C,Boshnaq M,Mangam S,Khushal A,Marzouk D,Tsavellas G

    更新日期:2017-10-01 00:00:00

  • Prospective comparison of return of bowel function after left versus right colectomy.

    abstract:BACKGROUND:Passage of flatus and stool represents a key milestone in recovery after colonic resections. Colorectal surgeons may hold varied expectations regarding recovery rates after left- versus right-sided colectomies, but there is currently little evidence to inform post-operative care. This study prospectively com...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ans.13823

    authors: Yuan L,O'Grady G,Milne T,Jaung R,Vather R,Bissett IP

    更新日期:2018-04-01 00:00:00

  • Modified elliptical rotation flap for sacrococcygeal pilonidal sinus disease.

    abstract:BACKGROUND:Although various surgical procedures have been described for pilonidal sinus disease, the best surgical technique is still controversial. The aim of this study was to evaluate the short-term results of modified elliptical rotation flap (MERF) for pilonidal sinus disease in terms of post-operative complicatio...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12818

    authors: Dizen H,Yoldas Ö,Yıldız M,Cilekar M,Dilektaşlı E

    更新日期:2014-10-01 00:00:00

  • Sentinel node biopsy and large (≥3 cm) breast cancer.

    abstract:BACKGROUND:Sentinel node biopsy is an accurate method for staging the axilla in early (small) breast cancers. However, data for the role of this technique for large breast cancers remain limited. METHOD:From the Royal Adelaide Hospital Sentinel Node database and the SNAC trial database, 100 subjects were identified wi...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12139

    authors: Beumer JD,Gill G,Campbell I,Wetzig N,Ung O,Farshid G,Uren R,Stockler M,Gebski V

    更新日期:2014-03-01 00:00:00

  • Prospective comparison of routine and selective operative cholangiography.

    abstract:BACKGROUND:In a rural centre with limited resources and no endoscopic retrograde cholangiopancreatography facilities, a prospective cohort study was established to compare policies of routine and selective intraoperative cholangiography (IOC) in order to develop a local protocol. METHODS:Patients undergoing laparoscop...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2005.03393.x

    authors: Amott D,Webb A,Tulloh B

    更新日期:2005-06-01 00:00:00

  • Necrotizing myositis: highlighting the hidden depths - case series and review of the literature.

    abstract:BACKGROUND:Necrotizing myositis (NM) is a life-threatening emergency. It causes focal muscle necrosis without abscess formation or extensive involvement of the overlying fascia and soft tissue. It is a clinical diagnosis requiring a high index of clinical suspicion. Usual presentation can readily be mistaken to represe...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/ans.15429

    authors: Khanna A,Gurusinghe D,Taylor D

    更新日期:2020-01-01 00:00:00

  • Extended endoscopic endonasal skull base surgery: from the sella to the anterior and posterior cranial fossa.

    abstract::Skull base surgery has gone through significant changes with the development of extended endoscopic endonasal approaches over the last decade. Initially used for the transphenoidal removal of hypophyseal adenomas, the endoscopic transnasal approach gradually evolved into a way of accessing the whole ventral skull base...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-2197.2011.05971.x

    authors: Oostra A,van Furth W,Georgalas C

    更新日期:2012-03-01 00:00:00

  • Surgical management of thoracic outlet syndrome: a 10-year experience.

    abstract:BACKGROUND:Thoracic Outlet Syndrome (TOS) refers to compression of the neurovascular structures in the region between the scalene muscles and the first rib, or by anatomical abnormalities such as cervical rib, fibrous bands and other variations in the scalene musculature. METHODS:Our experience with 63 consecutive ope...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2004.03016.x

    authors: Samarasam I,Sadhu D,Agarwal S,Nayak S

    更新日期:2004-06-01 00:00:00

  • Laparoscopic versus robotic-assisted radical prostatectomy: an Australian single-surgeon series.

    abstract:BACKGROUND:In Australia, robotic-assisted radical prostatectomy (RARP) has steadily replaced open and laparoscopic surgery in the management of localized prostate cancer. Given the increased cost of this technology, we aimed to compare the perioperative, pathological, oncological and functional outcomes as well as shor...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12602

    authors: Papachristos A,Basto M,Te Marvelde L,Moon D

    更新日期:2015-03-01 00:00:00

  • Process measure aimed at reducing time to haemorrhage control: outcomes associated with Code Crimson activation in exsanguinating truncal trauma.

    abstract:BACKGROUND:Major trauma activation is a process that mobilizes personnel and resources required to care for severely injured patients. Exsanguinating truncal trauma patients require an additional response beyond major trauma activation aimed at expediting haemorrhage control. To address this requirement, 'Code Crimson'...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.15650

    authors: Tovmassian D,Hameed AM,Ly J,Pathmanathan N,Devadas M,Gomez D,Hsu JM

    更新日期:2020-04-01 00:00:00

  • Bach and His.

    abstract::This paper examines the career of Johann Sebastian Bach (1685-1750) and the role played by Wilhelm His I (who was, with Albert von Haller, a noted pioneer of physiology) in the exhumation of Bach's remains in 1894. His's examination of these remains allowed the sculptor Carl Seffner to produce the celebrated statue of...

    journal_title:ANZ journal of surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1111/ans.12398

    authors: Beasley W

    更新日期:2014-12-01 00:00:00

  • Long-term venous access insertion: 'the learning curve'.

    abstract:BACKGROUND:The central venous access port device (CVAPD) provides reliable vascular access and is used for delivery of fluids and for obtaining blood samples. However, it can carry some intra- and post-operative complications such as thrombosis, pneumothorax, catheter fracture and port malposition. This article describ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13338

    authors: Fosh B,Canepa M,Eaton M

    更新日期:2016-12-01 00:00:00

  • Bilateral thoracoscopy, mediastinoscopy and laparoscopy, in addition to CT, MRI and PET imaging, are essential to correctly stage and treat patients with mesothelioma prior to trimodality therapy.

    abstract:BACKGROUND:Trimodality therapy (TMT; extrapleural pneumonectomy (EPP), chemotherapy and radiation therapy) offers the potential of optimal survival in selected patients with Brigham stage I-II epitheliod mesothelioma based on CT, MRI and PET scanning. We hypothesized that these scanning modalities were inadequate to ac...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2009.05060.x

    authors: Alvarez JM,Hasani A,Segal A,Sterret G,Millward M,Nowak A,Musk W,Bydder S

    更新日期:2009-10-01 00:00:00

  • Measurement of rotational deformity: using a smartphone application is more accurate than conventional methods.

    abstract:BACKGROUND:We assessed the accuracy of three different methods measuring the angle between two fixed Kirschner wires for the potential purpose of determining correction during rotational osteotomy of long bones. METHODS:Thirty-one orthopaedic consultants and registrars were prospectively asked to measure the angle bet...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.12371

    authors: Graham D,Suzuki A,Reitz C,Saxena A,Kuo J,Tetsworth K

    更新日期:2013-12-01 00:00:00

  • Workplace-based assessment: assessing technical skill throughout the continuum of surgical training.

    abstract::The Royal Colleges of Surgeons and Surgical Specialty Associations in the UK have introduced competence-based syllabi and curricula for surgical training. The syllabi of the Intercollegiate Surgical Curriculum Programme (ISCP) and Orthopaedic Curriculum and Assessment Programme (OCAP) define the core competencies, tha...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2008.04832.x

    authors: Beard J,Rowley D,Bussey M,Pitts D

    更新日期:2009-03-01 00:00:00

  • Impact of post-operative serum albumin level on anastomotic leakage after transthoracic oesophagectomy for oesophageal squamous cell carcinoma.

    abstract:BACKGROUND:The correlation of post-operative serum albumin level with the occurrence of anastomotic leakage (AL) in oesophageal squamous cell carcinoma (ESCC) remains unclear. The aim of this study was to evaluate the impact of post-operative serum albumin level on AL after transthoracic oesophagectomy. METHODS:Patien...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.16406

    authors: Zhuge L,Zheng D,Mao H,Xiang J,Chen H

    更新日期:2020-11-05 00:00:00

  • Systematic review of the impact of sacral neuromodulation on clinical symptoms and gastrointestinal physiology.

    abstract:BACKGROUND:Sacral neuromodulation (SNM) has emerged as a treatment option for faecal incontinence (FI). However, its objective effect on symptoms and anorectal function is inconsistently described. This study aimed to systematically review the impact of SNM on clinical symptoms and gastrointestinal physiology in patien...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/ans.13257

    authors: Mirbagheri N,Sivakumaran Y,Nassar N,Gladman MA

    更新日期:2016-04-01 00:00:00

  • Wound tension and 'closability' with keystone flaps, V-Y flaps and primary closure: a study in fresh-frozen cadavers.

    abstract:BACKGROUND:Previous publications have implied that the keystone flap provides mechanical benefits compared to primary closure. This has not been objectively demonstrated. METHODS:Elliptical defects were created in 'fresh-frozen' cadaveric specimens. Two approaches were used to investigate the potential mechanical bene...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14163

    authors: Donovan LC,Douglas CD,Van Helden D

    更新日期:2018-05-01 00:00:00