Abstract:
BACKGROUND:Necrotizing myositis (NM) is a life-threatening emergency. It causes focal muscle necrosis without abscess formation or extensive involvement of the overlying fascia and soft tissue. It is a clinical diagnosis requiring a high index of clinical suspicion. Usual presentation can readily be mistaken to represent more benign pathologies such as muscular injury, viral myopathy or deep venous thrombosis. The clinical course following initial misdiagnosis is rapid deterioration into profound sepsis and progressive multiorgan failure. Prompt treatment is associated with favourable outcomes, but early diagnosis is challenging due to initial absence of cutaneous signs and symptoms. Delayed referral to surgeons with appropriate expertise results in higher morbidity and mortality. The cornerstones to treatment are complete surgical debridement, intensive care management and accurate antimicrobial therapy. METHODS:We report four cases of NM demonstrating classical scenarios of initial misdiagnosis, delays in referral and review by an experienced surgeon. A review of the current literature to aid with overall management is also included. RESULTS:Review of literature that revealed the most common presentation was antecedent prodromal flu-like symptoms followed by rapidly progressing focal muscle pain. Patients were initially misdiagnosed followed by rapid deterioration into profound sepsis before surgical opinion was obtained. CONCLUSION:NM is a rare and potentially fatal disease that must be considered in the differential diagnoses of the young, healthy patient with acute limb pain and fever. A high index of suspicion will facilitate earlier management and reduce morbidity and mortality.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Khanna A,Gurusinghe D,Taylor Ddoi
10.1111/ans.15429subject
Has Abstractpub_date
2020-01-01 00:00:00pages
130-134issue
1-2eissn
1445-1433issn
1445-2197journal_volume
90pub_type
杂志文章,评审abstract:BACKGROUND:Single-incision laparoscopic cholecystectomy (SILC) is a common procedure performed worldwide. In this study, we evaluated the safety and efficacy of SILC for acute cholecystitis. METHODS:Patients who underwent SILC between September 2012 and December 2016 were retrospectively enrolled and divided into acut...
journal_title:ANZ journal of surgery
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更新日期:2018-07-01 00:00:00
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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更新日期:2005-10-01 00:00:00
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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journal_title:ANZ journal of surgery
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更新日期:2013-09-01 00:00:00
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2020-08-31 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2004-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.t01-1-02650.x
更新日期:2003-06-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12967
更新日期:2016-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1111/ans.12211
更新日期:2013-10-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13648
更新日期:2018-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04484.x
更新日期:2008-05-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
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更新日期:2012-06-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2016-09-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
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pub_type: 历史文章,杂志文章
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更新日期:2002-10-01 00:00:00
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更新日期:2018-07-01 00:00:00
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更新日期:2015-05-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
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更新日期:2014-12-01 00:00:00