Abstract:
BACKGROUND:Chlorhexidine (CHL) has antiseptic and disinfectant properties used to prevent hospital-acquired infections. CHL-induced anaphylaxis is poorly reported in surgical literature despite government warnings and growing recognition. The aim of this review is to increase awareness of CHL-induced anaphylaxis in the surgical population. METHODS:Literature review of Embase, Medline, PubMed and the Cochrane library using 'anaphylaxis (and) chlorhexidine' search terms. RESULTS:Thirty-six articles were published on surgical patients suffering anaphylaxis to CHL. Within these, seven patients had two proven separate anaphylactic reactions and one had three separate proven anaphylactic reactions. The most commonly affected speciality was urology. The majority occurred during elective procedures. A history of atopy was surprisingly uncommon as was bronchospasm. Six patients required active chest compressions and 39.71% of patients had their surgical procedure abandoned. Unplanned intensive care admissions occurred in 27.94%. DISCUSSION:In order to reduce abandoned procedures, unplanned intensive care unit admissions, morbidity and mortality associated with CHL-induced anaphylaxis we recommend the following: rationalization of CHL-containing products, greater vigilance regarding subtle symptoms of CHL allergy, appropriate investigation of these symptoms and a greater awareness of CHL-containing products. Lastly, we outline the appropriate investigations and highlight the need for meticulous documentation in those who are CHL allergic.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Sharp G,Green S,Rose Mdoi
10.1111/ans.13269subject
Has Abstractpub_date
2016-04-01 00:00:00pages
237-43issue
4eissn
1445-1433issn
1445-2197journal_volume
86pub_type
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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pub_type: 历史文章,杂志文章
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更新日期:2009-12-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,多中心研究
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更新日期:2014-09-01 00:00:00
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02429.x
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abstract:BACKGROUND:Anal intra-epithelial neoplasia (AIN) is believed to be a precursor to squamous cell carcinoma of the anus. The risk of developing anal cancer in patients with AIN, although known to occur, has been thought to be relatively low. This study reviews our experience with AIN, reviewing the incidence and risk fac...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2006-08-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
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更新日期:2018-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2006-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2010-10-01 00:00:00
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journal_title:ANZ journal of surgery
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pub_type: 临床试验,杂志文章
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
pub_type: 临床试验,杂志文章
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2008-06-01 00:00:00