当前位置： SCI文献检索 > NUCLEIC ACIDS RESEARCH期刊下所有文献 > rDNA in Locusta migratoria is very variable: two introns and extensive restriction site polymorphisms in the spacer.

rDNA in Locusta migratoria is very variable: two introns and extensive restriction site polymorphisms in the spacer.

Abstract：

:Cloned ribosomal DNA (rDNA) of Locusta migratoria was analyzed by restriction site mapping and SI nuclease experiments. The repeat unit is 18 kb long. The nontranscribed spacer region (NTS) is very large (11 kb) and homogeneous in length, but many of the restriction sites are heterogeneous among the repeat units. Two introns of different length were found at different positions in the 28S gene. They are present in less than 5% of the genes.

journal_name

Nucleic Acids Res

journal_title

Nucleic acids research

authors

Schäfer M,Kunz W

doi

10.1093/nar/13.4.1251

subject

Has Abstract

pub_date

1985-02-25 00:00:00

pages

1251-66

issue

4

eissn

0305-1048

issn

1362-4962

journal_volume

13

pub_type

杂志文章

相关文献

NUCLEIC ACIDS RESEARCH文献大全
  • Patscanui: an intuitive web interface for searching patterns in DNA and protein data.

    abstract：:Patterns in biological sequences frequently signify interesting features in the underlying molecule. Many tools exist to search for well-known patterns. Less support is available for exploratory analysis, where no well-defined patterns are known yet. PatScanUI (https://patscan.secondarymetabolites.org/) provides a hig...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gky321

    authors： Blin K,Wohlleben W,Weber T

    更新日期：2018-07-02 00:00:00

  • SITEHOUND-web: a server for ligand binding site identification in protein structures.

    abstract：:SITEHOUND-web (http://sitehound.sanchezlab.org) is a binding-site identification server powered by the SITEHOUND program. Given a protein structure in PDB format SITEHOUND-web will identify regions of the protein characterized by favorable interactions with a probe molecule. These regions correspond to putative ligand...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkp281

    authors： Hernandez M,Ghersi D,Sanchez R

    更新日期：2009-07-01 00:00:00

  • CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance.

    abstract：:To prevent progressive telomere shortening as a result of conventional DNA replication, new telomeric DNA must be added onto the chromosome end. The de novo DNA synthesis involves elongation of the G-rich strand of the telomere by telomerase. In human cells, the CST complex (CTC1-STN1-TEN1) also functions in telomere ...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkx125

    authors： Feng X,Hsu SJ,Kasbek C,Chaiken M,Price CM

    更新日期：2017-05-05 00:00:00

  • Rolling circle amplification shows a sinusoidal template length-dependent amplification bias.

    abstract：:Biophysical properties of DNA such as its longitudinal and torsional persistence length govern many processes and phenomena in biology, DNA nanotechnology and biotechnology. It has, for example, long been known that the circularization efficiency of short DNA fragments shows a periodic pattern where fragments with int...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkx1238

    authors： Joffroy B,Uca YO,Prešern D,Doye JPK,Schmidt TL

    更新日期：2018-01-25 00:00:00

  • Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins.

    abstract：:Homing endonucleases (HEs) cut long DNA target sites with high specificity to initiate and target the lateral transfer of mobile introns or inteins. This high site specificity of HEs makes them attractive reagents for gene targeting to promote DNA modification or repair. We have generated several hundred catalytically...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkp004

    authors： Li H,Pellenz S,Ulge U,Stoddard BL,Monnat RJ Jr

    更新日期：2009-04-01 00:00:00

  • Synthesis and characterization of a ribavirin-3',5'-phosphate pentadecamer homoribopolymer bearing a 5'-amino tether group and a 3'-thymidine.

    abstract：:The synthesis of a pentadecamer of the 5'-phosphate of the antiviral nucleoside ribavirin (1'-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide) has been achieved. This homoribopolymer is terminated at the 5'-position with an (6-aminohexyl)phosphate group to permit conjugation to a carrier and at the 3'-position by...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/18.5.1099

    authors： Dawson MI,Jina AN,Torkelson S,Rhee S,Moore M,Zarling DA,Hobbs PD

    更新日期：1990-03-11 00:00:00

  • Summaries of Affymetrix GeneChip probe level data.

    abstract：:High density oligonucleotide array technology is widely used in many areas of biomedical research for quantitative and highly parallel measurements of gene expression. Affymetrix GeneChip arrays are the most popular. In this technology each gene is typically represented by a set of 11-20 pairs of probes. In order to o...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gng015

    authors： Irizarry RA,Bolstad BM,Collin F,Cope LM,Hobbs B,Speed TP

    更新日期：2003-02-15 00:00:00

  • The effects of a unique D-loop structure of a minor tRNA(UUALeu) from Streptomyces on its structural stability and amino acid accepting activity.

    abstract：:Streptomyces bldA gene, which encodes a tRNA corresponding to a very minor leucine codon, UUA, regulates pleiotropic gene expression which is involved in sporulation and secondary metabolism. The unique structural feature of this tRNA is the lack of GG sequence in dihydrouridine loop (D-loop) that generally is conserv...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/20.15.3911

    authors： Ueda Y,Kumagai I,Miura K

    更新日期：1992-08-11 00:00:00

  • Methylase-limited partial NotI cleavage for physical mapping of genomic DNA.

    abstract：UNLABELLED:Partial cleavage of DNA with the restriction endonuclease NotI (5'...GC/GGCCGC...3') is an important technique for genomic mapping. However, partial genomic cleavage with this enzyme is impaired by the agarose matrix in which the DNA must be suspended. To solve this problem we have purified the blocking meth...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/18.11.3287

    authors： Hanish J,McClelland M

    更新日期：1990-06-11 00:00:00

  • Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat.

    abstract：:We have previously identified a T lymphocyte protein which binds to a site within the LTR of the human immunodeficiency virus type 1 (HIV-1) and exerts an inhibitory effect on virus gene expression. The palindromic site (site B) recognized by this protein is related to the palindromic binding sites of members of the s...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/20.20.5429

    authors： Orchard K,Lang G,Collins M,Latchman D

    更新日期：1992-10-25 00:00:00

  • SBSPKS: structure based sequence analysis of polyketide synthases.

    abstract：:Polyketide synthases (PKSs) catalyze biosynthesis of a diverse family of pharmaceutically important secondary metabolites. Bioinformatics analysis of sequence and structural features of PKS proteins plays a crucial role in discovery of new natural products by genome mining, as well as in design of novel secondary meta...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkq340

    authors： Anand S,Prasad MV,Yadav G,Kumar N,Shehara J,Ansari MZ,Mohanty D

    更新日期：2010-07-01 00:00:00

  • An NMR and mutational study of the pseudoknot within the gene 32 mRNA of bacteriophage T2: insights into a family of structurally related RNA pseudoknots.

    abstract：:NMR methods were used to investigate a series of mutants of the pseudoknot within the gene 32 messenger RNA of bacteriophage T2, for the purpose of investigating the range of sequences, stem and loop lengths that can form a similar pseudoknot structure. This information is of particular relevance since the T2 pseudokn...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/25.6.1130

    authors： Du Z,Hoffman DW

    更新日期：1997-03-15 00:00:00

  • Tendencies of 31P chemical shifts changes in NMR spectra of nucleotide derivatives.

    abstract：:31P NMR chemical shifts of the selected mono- and oligonucleotide derivatives, including the compounds with P-N, P-C, P-S bonds and phosphite nucleotide analogues have been presented. The influence of substituents upon 31P chemical shifts has been discussed. The concrete examples of 31P chemical shifts data applicatio...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/12.14.5547

    authors： Lebedev AV,Rezvukhin AI

    更新日期：1984-07-25 00:00:00

  • Argonaute binding within 3'-untranslated regions poorly predicts gene repression.

    abstract：:Despite two decades of study, the full scope of RNAi in mammalian cells has remained obscure. Here we combine: (i) Knockout of argonaute (AGO) variants; (ii) RNA sequencing analysis of gene expression changes and (iii) Enhanced Crosslinking Immunoprecipitation Sequencing (eCLIP-seq) using anti-AGO2 antibody to identif...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkaa478

    authors： Chu Y,Kilikevicius A,Liu J,Johnson KC,Yokota S,Corey DR

    更新日期：2020-07-27 00:00:00

  • Human aldolase isozyme gene: the structure of multispecies aldolase B mRNAs.

    abstract：:A complete nucleotide sequence of human aldolase B mRNA was determined with a recombinant cDNA (pHABL120-3). The cDNA insert was composed of 1,652 bases excluding poly(A) tail and the sequence was consistent with the previous results reported by others. However, S1 nuclease mapping and subsequent genomic analysis allo...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/13.14.5055

    authors： Sakakibara M,Mukai T,Yatsuki H,Hori K

    更新日期：1985-07-25 00:00:00

  • Identification and characterisation of PmaCI an endonuclease of novel specificity from Pseudomonas maltophila.

    abstract：:We report the use of MonoQ FPLC (Fast Protein Liquid Chromatography) for the rapid purification of a novel Type II restriction endonuclease PmaCI, from Pseudomonas maltophila, which recognises the sequence 5'-CAC decreases GTG-3'. The resulting enzyme is free of other nucleases to a level suitable for its characterisa...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/14.3.1293

    authors： Walker JN,Dean PD,Saunders JR

    更新日期：1986-02-11 00:00:00

  • Intron mobility in phage T4 is dependent upon a distinctive class of endonucleases and independent of DNA sequences encoding the intron core: mechanistic and evolutionary implications.

    abstract：:Although mobility of the phylogenetically widespread group I introns appears to be mechanistically similar, the phage T4 intron-encoded endonucleases that promote mobility of the td and sunY introns are different from their eukaryotic counterparts. Most notably, they cleave at a distance from the intron insertion site...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/18.13.3763

    authors： Bell-Pedersen D,Quirk S,Clyman J,Belfort M

    更新日期：1990-07-11 00:00:00

  • An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo.

    abstract：:We describe a versatile genetic system for rapid analysis of mammalian gene function. In this, loss of reporter activity in a novel embryonic stem (ES) cell line enables rapid identification of targeting to the ubiquitously expressed Rosa26 locus. Subsequent regulation of gene activity is governed by a dual regulatory...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gni146

    authors： Mao J,Barrow J,McMahon J,Vaughan J,McMahon AP

    更新日期：2005-10-12 00:00:00

  • Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1.

    abstract：:Mammalian cryptochromes (Crys) are essential circadian clock factors implicated in diverse clock-independent physiological functions, including DNA damage responses. Here we show that Cry1 modulates the ATR-mediated DNA damage checkpoint (DDC) response by interacting with Timeless (Tim) in a time-of-day-dependent mann...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gku094

    authors： Kang TH,Leem SH

    更新日期：2014-04-01 00:00:00

  • A 'new lease of life': FnCpf1 possesses DNA cleavage activity for genome editing in human cells.

    abstract：:Cpf1 nucleases were recently reported to be highly specific and programmable nucleases with efficiencies comparable to those of SpCas9. AsCpf1 and LbCpf1 require a single crRNA and recognize a 5'-TTTN-3' protospacer adjacent motif (PAM) at the 5' end of the protospacer for genome editing. For widespread application in...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkx783

    authors： Tu M,Lin L,Cheng Y,He X,Sun H,Xie H,Fu J,Liu C,Li J,Chen D,Xi H,Xue D,Liu Q,Zhao J,Gao C,Song Z,Qu J,Gu F

    更新日期：2017-11-02 00:00:00

  • Solution structure of duplex DNA containing an extrahelical abasic site analog determined by NMR spectroscopy and molecular dynamics.

    abstract：:Translesional DNA synthesis past abasic sites proceeds with the preferential incorporation of dAMP opposite the lesion and, depending on the sequence context, one or two base deletions. High-resolution NMR spectroscopy and molecular dynamics simulations were used to determine the three-dimensional structure of a DNA h...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/26.10.2385

    authors： Lin Z,Hung KN,Grollman AP,de los Santos C

    更新日期：1998-05-15 00:00:00

  • SUVH1, a Su(var)3-9 family member, promotes the expression of genes targeted by DNA methylation.

    abstract：:Transposable elements are found throughout the genomes of all organisms. Repressive marks such as DNA methylation and histone H3 lysine 9 (H3K9) methylation silence these elements and maintain genome integrity. However, how silencing mechanisms are themselves regulated to avoid the silencing of genes remains unclear. ...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkv958

    authors： Li S,Liu L,Li S,Gao L,Zhao Y,Kim YJ,Chen X

    更新日期：2016-01-29 00:00:00

  • Identifying functional gene sets from hierarchically clustered expression data: map of abiotic stress regulated genes in Arabidopsis thaliana.

    abstract：:We present MultiGO, a web-enabled tool for the identification of biologically relevant gene sets from hierarchically clustered gene expression trees (http://ekhidna.biocenter.helsinki.fi/poxo/multigo). High-throughput gene expression measuring techniques, such as microarrays, are nowadays often used to monitor the exp...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkl694

    authors： Kankainen M,Brader G,Törönen P,Palva ET,Holm L

    更新日期：2006-01-01 00:00:00

  • Codon preference in Dictyostelium discoideum.

    abstract：:Dictyostelium discoideum is of increasing interest as a model eukaryotic cell because its many attributes have recently been expanded to include improved genetic and biochemical manipulability. The ability to transform Dictyostelium using drug resistance as a selectable marker (1) and to gene target by high frequency ...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/16.14.6617

    authors： Warrick HM,Spudich JA

    更新日期：1988-07-25 00:00:00

  • On the mechanism of the modular primer effect.

    abstract：:Modular primers are strings of three contiguously annealed unligated oligonucleotides (modules) as short as 5- or 6-mers, selected from a presynthesized library. It was previously found that such strings can prime DNA sequencing reactions specifically, thus eliminating the need for the primer synthesis step in DNA seq...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/23.15.2881

    authors： Beskin AD,Zevin-Sonkin D,Sobolev IA,Ulanovsky LE

    更新日期：1995-08-11 00:00:00

  • ORFDB: an information resource linking scientific content to a high-quality Open Reading Frame (ORF) collection.

    abstract：:The ORFDB (http://orf.invitrogen.com/) represents an ongoing effort at Invitrogen Corporation to integrate relevant scientific data with an evolving collection of human and mouse Open Reading Frame (ORF) clones (Ultimate ORF Clones). The ORFDB serves as a central data warehouse enabling researchers to search the ORF c...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkh118

    authors： Liang F,Matrubutham U,Parvizi B,Yen J,Duan D,Mirchandani J,Hashima S,Nguyen U,Ubil E,Loewenheim J,Yu X,Sipes S,Williams W,Wang L,Bennett R,Carrino J

    更新日期：2004-01-01 00:00:00

  • W-IQ-TREE: a fast online phylogenetic tool for maximum likelihood analysis.

    abstract：:This article presents W-IQ-TREE, an intuitive and user-friendly web interface and server for IQ-TREE, an efficient phylogenetic software for maximum likelihood analysis. W-IQ-TREE supports multiple sequence types (DNA, protein, codon, binary and morphology) in common alignment formats and a wide range of evolutionary ...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkw256

    authors： Trifinopoulos J,Nguyen LT,von Haeseler A,Minh BQ

    更新日期：2016-07-08 00:00:00

  • OMA 2011: orthology inference among 1000 complete genomes.

    abstract：:OMA (Orthologous MAtrix) is a database that identifies orthologs among publicly available, complete genomes. Initiated in 2004, the project is at its 11th release. It now includes 1000 genomes, making it one of the largest resources of its kind. Here, we describe recent developments in terms of species covered; the al...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkq1238

    authors： Altenhoff AM,Schneider A,Gonnet GH,Dessimoz C

    更新日期：2011-01-01 00:00:00

  • RNA polymerase II transcription inhibits DNA repair by photolyase in the transcribed strand of active yeast genes.

    abstract：:Yeast uses nucleotide excision repair (NER) and photolyase (photoreactivation) to repair cyclobutane pyrimidine dimers (CPDs) generated by ultraviolet light. In active genes, NER preferentially repairs the transcribed strand (TS). In contrast, we recently showed that photolyase preferentially repairs the non-transcrib...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/25.19.3795

    authors： Livingstone-Zatchej M,Meier A,Suter B,Thoma F

    更新日期：1997-10-01 00:00:00

  • The effect of hybridization-induced secondary structure alterations on RNA detection using backscattering interferometry.

    abstract：:Backscattering interferometry (BSI) has been used to successfully monitor molecular interactions without labeling and with high sensitivity. These properties suggest that this approach might be useful for detecting biomarkers of infection. In this report, we identify interactions and characteristics of nucleic acid pr...

    journal_title：Nucleic acids research

    pub_type： 杂志文章

    doi：10.1093/nar/gkt165

    authors： Adams NM,Olmsted IR,Haselton FR,Bornhop DJ,Wright DW

    更新日期：2013-05-01 00:00:00