A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility.

abstract：BACKGROUND:The taxonomy of tintinnine ciliates is vastly unresolved because it has traditionally been based on the lorica (a secreted shell) and it has only recently incorporated cytological and molecular information. Tintinnopsis, the most speciose tintinnine genus, is also the most problematic: it is known to be non-...

journal_title：BMC microbiology

authors： Bai Y,Wang R,Song W,Li L,Santoferrara LF,Hu X

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:Antimicrobial resistance is currently a major global issue. As the rate of emergence of antimicrobial resistance has superseded the rate of discovery and introduction of new effective drugs, the medical arsenal now is experiencing shortage of effective drugs to combat diseases, particularly against diseases ...

journal_title：BMC microbiology

authors： Teh CH,Nazni WA,Nurulhusna AH,Norazah A,Lee HL

更新日期：2017-02-16 00:00:00

abstract：BACKGROUND:Streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. It is also an emerging human pathogen. RESULTS:Here we provide characterization of the first genome sequence for this species, strai...

journal_title：BMC microbiology

authors： Richards VP,Zadoks RN,Pavinski Bitar PD,Lefébure T,Lang P,Werner B,Tikofsky L,Moroni P,Stanhope MJ

更新日期：2012-12-18 00:00:00

abstract：BACKGROUND:Following genital chlamydial infection, an early T helper type 1 (Th1)-associated immune response precedes the activation and recruitment of specific Th1 cells bearing distinct chemokine receptors, subsequently leading to the clearance of Chlamydia. We have shown that CCR5, a receptor for CCL5, is crucial fo...

journal_title：BMC microbiology

authors： Sakthivel SK,Singh UP,Singh S,Taub DD,Igietseme JU,Lillard JW Jr

更新日期：2008-08-13 00:00:00

abstract：BACKGROUND:Escherichia coli strains are commonly found in the gut microflora of warm-blooded animals. These strains can be assigned to one of the four main phylogenetic groups, A, B1, B2 and D, which can be divided into seven subgroups (A0, A1, B1, B22, B23, D1 and D2), according to the combination of the three genetic...

journal_title：BMC microbiology

authors： Carlos C,Pires MM,Stoppe NC,Hachich EM,Sato MI,Gomes TA,Amaral LA,Ottoboni LM

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Malic enzymes decarboxylate the tricarboxylic acid (TCA) cycle intermediate malate to the glycolytic end-product pyruvate and are well positioned to regulate metabolic flux in central carbon metabolism. Despite the wide distribution of these enzymes, their biological roles are unclear in part because the rea...

journal_title：BMC microbiology

authors： Zhang Y,Smallbone LA,diCenzo GC,Morton R,Finan TM

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:The low bacterial load in samples acquired from the lungs, have made studies on the airway microbiome vulnerable to contamination from bacterial DNA introduced during sampling and laboratory processing. We have examined the impact of laboratory contamination on samples collected from the lower airways by pro...

journal_title：BMC microbiology

authors： Drengenes C,Wiker HG,Kalananthan T,Nordeide E,Eagan TML,Nielsen R

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:With the growing demand for fossil fuels and the severe energy crisis, lignocellulose is widely regarded as a promising cost-effective renewable resource for ethanol production, and the use of lignocellulose residues as raw material is remarkable. Polar organisms have important value in scientific research a...

journal_title：BMC microbiology

authors： Cong B,Wang N,Liu S,Liu F,Yin X,Shen J

更新日期：2017-05-30 00:00:00

abstract：BACKGROUND:Exposure of cells to environmental stress conditions can lead to the interruption of several intracellular processes, in particular those performed by macromolecular complexes such as the spliceosome. RESULTS:During nucleotide sequencing of cDNA libraries constructed using RNA isolated from B. emersonii cel...

journal_title：BMC microbiology

authors： Georg RC,Stefani RM,Gomes SL

更新日期：2009-10-29 00:00:00

abstract：BACKGROUND:The evolution of mycoplasmas from a common ancestor with Firmicutes has been characterized not only by genome down-sizing but also by horizontal gene transfer between mycoplasma species sharing a common host. The mechanisms of these gene transfers remain unclear because our knowledge of the mycoplasma mobile...

journal_title：BMC microbiology

authors： Breton M,Tardy F,Dordet-Frisoni E,Sagne E,Mick V,Renaudin J,Sirand-Pugnet P,Citti C,Blanchard A

更新日期：2012-11-12 00:00:00

abstract：BACKGROUND:Wogonin, a natural flavonoid-like chemical compound, exhibits anti-inflammatory, antitumor, antiviral, neuroprotective, and anxiolytic effects by modulating a variety of cellular signaling pathways including PI3K-Akt, p53, nuclear factor κB (NF-κB), mitogen-activated protein kinase (MAPK) pathways. In this s...

journal_title：BMC microbiology

authors： Chu Y,Lv X,Zhang L,Fu X,Song S,Su A,Chen D,Xu L,Wang Y,Wu Z,Yun Z

更新日期：2020-07-28 00:00:00

abstract：BACKGROUND:Hfq is a widely conserved bacterial RNA-binding protein which generally mediates the global regulatory activities involv ed in physiological process and virulence. The goal of this study was to characterize the biological function of hfq gene in Xanthomonas axonpodis pv. citri (Xac), the causal agent of citr...

journal_title：BMC microbiology

authors： Liu X,Yan Y,Wu H,Zhou C,Wang X

更新日期：2019-05-22 00:00:00

abstract：BACKGROUND:The sequenced O45:K1:H7 Escherichia coli meningitis strain S88 harbors a large virulence plasmid. To identify possible genetic determinants of pS88 virulence, we examined the transcriptomes of 88 plasmidic ORFs corresponding to known and putative virulence genes, and 35 ORFs of unknown function. RESULTS:Qua...

journal_title：BMC microbiology

authors： Lemaître C,Bidet P,Bingen E,Bonacorsi S

更新日期：2012-06-21 00:00:00

abstract：BACKGROUND:The heme acquisition machinery in Streptococcus pyogenes is believed to consist of the surface proteins, Shr and Shp, and heme-specific ATP-binding cassette transporter HtsABC. Shp has been shown to rapidly transfer its heme to the lipoprotein component, HtsA, of HtsABC. The function of Shr and the heme sour...

journal_title：BMC microbiology

authors： Zhu H,Liu M,Lei B

更新日期：2008-01-23 00:00:00

abstract：BACKGROUND:Thermotolerant Campylobacter is among the more prevalent bacterial pathogens that cause foodborne diseases. This study aimed at evaluating the occurrence of thermotolerant Campylobacter contamination in chicken carcasses and processing plant stations (chilling water, scalding water, defeathering machinery, e...

journal_title：BMC microbiology

authors： Figueroa G,Troncoso M,López C,Rivas P,Toro M

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:The emergence and spread of multidrug resistant methicillin-resistant Staphylococcus aureus (MDR-MRSA) has serious health consequences in the presence of sub-MIC antibiotics. Therefore, this study was designed to evaluate β-lactamase activity, efflux activity, biofilm formation, and gene expression pattern i...

journal_title：BMC microbiology

authors： Jo A,Ahn J

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:The ability of an intracellular pathogen to establish infection depends on the capacity of the organism to survive and replicate inside the host. Mycobacterium fortuitum is a bacteria that contains genes involved in the detoxification of the oxygen reactive species such as those produced by the host during t...

journal_title：BMC microbiology

authors： Núñez MC,Menéndez MC,Rebollo MJ,García MJ

更新日期：2008-06-19 00:00:00

abstract：BACKGROUND:Alpha-isopropylmalate synthase (alpha-IPMS) is the key enzyme that catalyzes the first committed step in the leucine biosynthetic pathway. The gene encoding alpha-IPMS in Mycobacterium tuberculosis, leuA, is polymorphic due to the insertion of 57-bp repeat units referred to as Variable Number of Tandem Repea...

journal_title：BMC microbiology

authors： Yindeeyoungyeon W,Likitvivatanavong S,Palittapongarnpim P

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:Total community rDNA was used to determine the diversity of bacteria and archaea from water, wet sediment and microbial mats samples of hot springs in the Eastern lowlands of Eritrea. The temperatures of the springs range from 49.5 °C to 100 °C while pH levels varied from 6.97 to 7.54. Akwar and Maiwooi have...

journal_title：BMC microbiology

authors： Ghilamicael AM,Budambula NLM,Anami SE,Mehari T,Boga HI

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:Cystic fibrosis (CF) lung disease has a unique profile of pathogens predominated by Pseudomonas aeruginosa (PsA) and Staphylococcus aureus (SA). These microorganisms must overcome host immune defense to colonize the CF lungs. Polymorphonuclear neutrophils are a major component of the host defense against bac...

journal_title：BMC microbiology

authors： Bonvillain RW,Painter RG,Ledet EM,Wang G

更新日期：2011-05-20 00:00:00

abstract：BACKGROUND:Fusobacterium nucleatum, a well studied bacterium in periodontal diseases, appendicitis, gingivitis, osteomyelitis and pregnancy complications has recently gained attention due to its association with colorectal cancer (CRC) progression. Treatment with berberine was shown to reverse F. nucleatum-induced CRC ...

journal_title：BMC microbiology

authors： Kumar A,Thotakura PL,Tiwary BK,Krishna R

更新日期：2016-05-12 00:00:00

abstract：BACKGROUND:The emergence of antibiotic resistant pathogenic bacteria has reduced our ability to combat infectious diseases. At the same time the numbers of new antibiotics reaching the market have decreased. This situation has created an urgent need to discover novel antibiotic scaffolds. Recently, the application of p...

journal_title：BMC microbiology

authors： Hoerr V,Duggan GE,Zbytnuik L,Poon KK,Große C,Neugebauer U,Methling K,Löffler B,Vogel HJ

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in reaching the different areas of the gastrointestinal tract (GIT) in vivo....

journal_title：BMC microbiology

authors： Marzorati M,Vanhoecke B,De Ryck T,Sadaghian Sadabad M,Pinheiro I,Possemiers S,Van den Abbeele P,Derycke L,Bracke M,Pieters J,Hennebel T,Harmsen HJ,Verstraete W,Van de Wiele T

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:Bacteria excrete costly toxins to defend their ecological niche. The evolution of such antagonistic interactions between individuals is expected to depend on both the social environment and the strength of resource competition. Antagonism is expected to be weak among highly similar genotypes because most ind...

journal_title：BMC microbiology

authors： Schoustra SE,Dench J,Dali R,Aaron SD,Kassen R

更新日期：2012-03-22 00:00:00

abstract：: ...

journal_title：BMC microbiology

authors： Abd-Alla AMM,Tsiamis G,Boucias DG

更新日期：2018-11-23 00:00:00

abstract：BACKGROUND:Prevotella intermedia is a Gram-negative black-pigmenting oral anaerobe associated with periodontitis in humans, and has a haem requirement for growth, survival and virulence. It produces an iron porphyrin-containing pigment comprising monomeric iron (III) protoporphyrin IX (Fe(III)PPIX.OH; haematin). The ba...

journal_title：BMC microbiology

authors： Byrne DP,Manandhar SP,Potempa J,Smalley JW

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:Chlamydia pneumoniae is a common human pathogen that is associated with upper and lower respiratory tract infections. It has also been suggested that C. pneumoniae infection can trigger or promote a number of chronic inflammatory conditions, including asthma and atherosclerosis. Several strains of C. pneumon...

journal_title：BMC microbiology

authors： He X,Liang Y,LaValley MP,Lai J,Ingalls RR

更新日期：2015-10-23 00:00:00

abstract：BACKGROUND:Vibrio anguillarum is an extracellular bacterial pathogen that is a causative agent of vibriosis in finfish and crustaceans with mortality rates ranging from 30% to 100%. Mutations in central metabolism (glycolysis and the TCA cycle) of intracellular pathogens often result in attenuated virulence due to depl...

journal_title：BMC microbiology

authors： Mou X,Spinard EJ,Hillman SL,Nelson DR

更新日期：2017-11-14 00:00:00

abstract：BACKGROUND:Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is generally employed for the rapid identification of fungal isolates. However, the results are based on s...

journal_title：BMC microbiology

authors： Nakamura S,Sato H,Tanaka R,Kusuya Y,Takahashi H,Yaguchi T

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a food-borne pathogen and the most common cause of infections in hospitalized patients. The increase in the resistance of this pathogen to antibacterials has made necessary the development of new anti-staphylococcal agents. In this context, bacteriophage lytic enzymes such as endolys...

journal_title：BMC microbiology

authors： Rodríguez L,Martínez B,Zhou Y,Rodríguez A,Donovan DM,García P

更新日期：2011-06-17 00:00:00