Effect of gastric bypass combined with ileal transportation on type 2 diabetes mellitus.

abstract：:The aim of the present study was to determine how Endostar inhibits tumor angiogenesis and increases radiation sensitivity when combined with radiotherapy. In vitro studies were conducted to analyze the expression levels of transforming growth factor-β1 (TGF-β1), hypoxia-inducible factor 1 (HIF-1α) and basic fibroblas...

journal_title：Experimental and therapeutic medicine

authors： Wu Y,Zheng Y,Shen Z,Ge W,Xie Y,Li C

更新日期：2014-04-01 00:00:00

abstract：:Recent studies have demonstrated that melatonin significantly decreased all studied acute pancreatitis-associated inflammatory parameters, in addition to reducing apoptosis and necrosis associated with pancreatic injury. However, the effect of melatonin on gut barrier dysfunction and bacterial translocation has not be...

journal_title：Experimental and therapeutic medicine

authors： Sun X,Shao Y,Jin Y,Huai J,Zhou Q,Huang Z,Wu J

更新日期：2013-12-01 00:00:00

abstract：:The aim of the present study was to investigate whether the co-injection of hyaluronic acid (HA) and corticosteroids (CS) was superior to HA alone in the treatment of knee OA. A total of 120 participants with symptomatic knee OA were recruited and formed the intention-to-treat population for a 6-month follow-up. In th...

journal_title：Experimental and therapeutic medicine

authors： Wang SZ,Wu DY,Chang Q,Guo YD,Wang C,Fan WM

更新日期：2018-09-01 00:00:00

abstract：:The aim of the present study was to evaluate the diagnostic value of interferon-γ release assays for the detection of active tuberculosis (ATB) in patients previously vaccinated with Bacillus Calmette-Guérin (BCG). In total, 540 patients underwent the T-SPOT.TB test, including 295 patients with active pulmonary TB (PT...

journal_title：Experimental and therapeutic medicine

authors： Yan L,Xiao H,Han M,Zhang Q

更新日期：2015-07-01 00:00:00

abstract：:Effects of triamcinolone acetonide (TA) combined with aminoguanidine (AG) on vascular endothelial function, vascular endothelial growth factor (VEGF) expression and retinal function in diabetic retinopathy (DR) patients were studied. A total of 100 patients with DR admitted to the Taizhou Second People's Hospital Affi...

journal_title：Experimental and therapeutic medicine

authors： Xu K,Qian H,Zou M

更新日期：2020-04-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a heterogeneous disease, with varying immunological and histopathological features. The CC chemokine ligand 19 (CCL19) can stimulate T cells and antigen-presenting cells into secondary lymphoid node formation, as observed in allergic rhinitis, inflammatory bowel disease and other inflam...

journal_title：Experimental and therapeutic medicine

authors： Zou Y,Wang Y,Wang SB,Kong YG,Xu YU,Tao ZZ,Chen SM

更新日期：2016-01-01 00:00:00

abstract：:The hyper-IgM syndromes (HIGMs) are a group of primary immune deficiency diseases characterized by a normal or elevated serum level of IgM and low or absent serum levels of IgG, IgA and IgE. Here, we report a case of X-linked HIGM with a new CD40L gene mutation presenting with eosinophilia. The patient experienced rec...

journal_title：Experimental and therapeutic medicine

authors： Guo LI,Chen BO,Xu B,Lu M,Ning B,Chen Z

更新日期：2015-04-01 00:00:00

abstract：:The aim of the present study was to investigate the protective effects of sodium ferulate (SF) on HT22 hippocampal cells under a high glucose concentration. Cells were cultured in normal glucose (25 mM D-glucose) or high glucose (50 mM D-glucose) with various concentrations of SF (50, 100, 250 or 500 µM) for 0, 48 and...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Liu L,Zhang L,Lv J,Guo X,Li X,Zhao T

更新日期：2019-09-01 00:00:00

abstract：:Ischemic heart disease is a major cause of mortality and disability worldwide. Timely reperfusion is currently the most effective method of treating ischemic heart disease; however, abrupt reperfusion may cause ischemia/reperfusion (I/R) injury. Apoptosis serves an important role in the progression of myocardial I/R i...

journal_title：Experimental and therapeutic medicine

authors： Tan H,Chen L,Ma J

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to investigate the safety, feasibility and mid-term results of laparoscopy-assisted surgery in the treatment of locally advanced gastric antral cancer. The clinical data of 50 patients who received laparoscopy-assisted surgery (Group A) and 62 patients who were treated by conventional laparot...

journal_title：Experimental and therapeutic medicine

authors： Fang F,Han F,Ding YL,Wang HJ

更新日期：2013-09-01 00:00:00

abstract：:Effects of dexmedetomidine on postoperative cognitive function in patients undergoing coronary artery bypass grafting were investigated. Eighty patients undergoing systemic anesthesia with extracorporeal coronary artery bypass grafting in The People's Hospital of Guangxi Zhuang Autonomous Region from January 2015 to A...

journal_title：Experimental and therapeutic medicine

authors： Gong Z,Li J,Zhong Y,Guan X,Huang A,Ma L

更新日期：2018-12-01 00:00:00

abstract：:Cardiovascular diseases are among the primary causes of decreased quality of life as well as mortality of hemodialysis patients with end-stage renal disease. The aim of the present study was to evaluate the predictive value of the red blood cell distribution width (RDW)-to-platelet ratio (RPR) and neutrophil-to-lympho...

journal_title：Experimental and therapeutic medicine

authors： Zhu X,Li G,Li S,Gong Z,Liu J,Song S

更新日期：2020-08-01 00:00:00

abstract：:Secreted frizzled-related protein 1 (SFRP1), which is an extracellular inhibitor involved in Wnt signalling, is downregulated by promoter hypermethylation in the early stages of colorectal tumorigenesis. Polycomb (PCG) and methyl-CpG-binding domain (MBD) proteins that serve a role in epigenetic gene regulation. The ai...

journal_title：Experimental and therapeutic medicine

authors： Yu J,Xie Y,Liu Y,Wang F,Li M,Qi J

更新日期：2020-12-01 00:00:00

abstract：:Clinical efficacy of montelukast sodium combined with budesonide or combined with loratadine in children with cough variant asthma was investigated. A retrospective analysis of the medical records of 72 children with cough variant asthma who were treated in Xuzhou Children's Hospital, Xuzhou Medical University from Ap...

journal_title：Experimental and therapeutic medicine

authors： Wei H,Li W,Jiang Z,Xi X,Qi G

更新日期：2019-07-01 00:00:00

abstract：:Lung cancer is an aggressive type of cancer that is associated with a high mortality rate. Lung cancer-initiating cells are populations of self-renewing cancer cells with pluripotent differentiation ability. Cancers typically originate from multiple phenotypically distinct cancer-initiating cells. CD133 and CD44 are s...

journal_title：Experimental and therapeutic medicine

authors： Huang X,Wan J,Leng D,Zhang Y,Yang S

更新日期：2020-01-01 00:00:00

abstract：:Thymic carcinoma is a rare thymic epithelial tumor in which chemotherapy for advanced disease has not yet been established. Thymidylate synthase (TS) and orotate phosphoribosyltransferase (OPRT) protein expression levels in thymic carcinoma were evaluated as possible indicators of the anticancer activity of 5-fluorour...

journal_title：Experimental and therapeutic medicine

authors： Yokota K,Sasaki H,Okuda K,Shitara M,Hikosaka Y,Moriyama S,Yano M,Fujii Y

更新日期：2012-10-01 00:00:00

abstract：:Gastric ulcer is one of the most common chronic gastrointestinal diseases characterized by a significant defect in the mucosal barrier. Helicobacter pylori (H. pylori) infection and the frequent long-term use of non-steroidal anti-inflammatory drugs are major factors involved in gastric ulcer development. Acid inhibit...

journal_title：Experimental and therapeutic medicine

authors： Khoder G,Al-Menhali AA,Al-Yassir F,Karam SM

更新日期：2016-07-01 00:00:00

abstract：:Successful eyelid reconstructions have been reported when using an axial nasal chondromucosal flap based on the dorsal nasal artery. The present study aimed to present a detailed anatomical description of the blood supply of the lateral nasal region and the angular artery, in order to propose the angular vessels as a ...

journal_title：Experimental and therapeutic medicine

authors： Hou D,Fang L,Zhao Z,Zhou C,Yang M

更新日期：2013-03-01 00:00:00

abstract：:Lysyl oxidase proteins (LOXs) are amine oxidases, which are mainly located in smooth muscle cells and fibroblasts and serve an important role in the formation of the extracellular matrix (ECM) in a copper-dependent manner. Owing to the ability of LOX proteins to modulate crosslinking between collagens and to promote t...

journal_title：Experimental and therapeutic medicine

authors： Wei S,Gao L,Wu C,Qin F,Yuan J

更新日期：2020-07-01 00:00:00

abstract：:Patients with spontaneous isolated superior mesenteric artery (SMA) dissection (SISMAD) usually present with acute or chronic abdominal pain and are admitted to the emergency or digestive diseases department to undergo auxiliary examinations, typically abdominal plain CT or contrast-enhanced CT (CECT). Plain CT is the...

journal_title：Experimental and therapeutic medicine

authors： Tan Z,Jin Q,Fan W,Han P,Li X

更新日期：2021-01-01 00:00:00

abstract：:Asthma is one of the diseases that demonstrates a wide range of variation in its clinical expression, in addition to an important heterogeneity in the pathophysiological mechanisms present in each case. The ever-increasing knowledge of the molecular signalling routes and the development of the Bio Immune(G)ene Medicin...

journal_title：Experimental and therapeutic medicine

authors： Glady G

更新日期：2018-06-01 00:00:00

abstract：:The main function of adipocyte fatty acid-binding protein (A-FABP) is to regulate fatty acid metabolism as its molecular chaperone. The clinical significance of A-FABP in hypoxic-ischemic brain damage (HIBD) neonates is not yet clear. Free fatty acid (FFA) in cerebral cortex increases along with hypoxia ischemia degre...

journal_title：Experimental and therapeutic medicine

authors： Li M,Jiang L,Zhang H,Wang D,Zhang M,Zhang L

更新日期：2016-08-01 00:00:00

abstract：:The knowledge of the expected time-to-positivity (TTP) of blood cultures by major pathogens is essential both clinically and economically. To this end, we conducted the present two-year study in our Institution, aiming to assess the TTP of all the major microorganisms including Enterobacteriaceae, Pseudomonas aerugino...

journal_title：Experimental and therapeutic medicine

authors： Moustos E,Staphylaki D,Christidou A,Spandidos DA,Neonakis IK

更新日期：2017-12-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2015.2860.]. ...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Xiao J,Shi X,Hao G,Chen Q,Zhou J,Wei X

更新日期：2019-04-01 00:00:00

abstract：:Successful islet isolation is crucial for islet transplantation and cell treatment for type 1 diabetes. Current isolation methods are able to obtain 500-1,000 islets per rat, which results in a waste of ≥50% of total islets. In the present study, a facile mechanical shaking method for improving islet yield (up to 1,50...

journal_title：Experimental and therapeutic medicine

authors： Yin N,Chen T,Yu Y,Han Y,Yan F,Zheng Z,Chen Z

更新日期：2016-12-01 00:00:00

abstract：:Implementation of comprehensive rehabilitation therapy in postoperative care of patients with cholangiocarcinoma was studied to explore its impact on patients' quality of life. Two hundred and nineteen patients with cholangiocarcinoma who underwent surgery in Yidu Central Hospital of Weifang from April 2014 to June 20...

journal_title：Experimental and therapeutic medicine

authors： Liu S,Zhou L,An L

更新日期：2019-04-01 00:00:00

abstract：:The aim of the present study was to investigate the role of homocysteine (Hcy) in the pathogenesis of pulmonary embolism (PE) and the associated molecular mechanisms in human umbilical vein endothelial cells (HUVECs). Hcy contents were detected with high-performance liquid chromatography. Apoptosis was detected by flo...

journal_title：Experimental and therapeutic medicine

authors： Yang F,Qi X,Gao Z,Yang X,Zheng X,Duan C,Zheng J

更新日期：2016-10-01 00:00:00

abstract：:Breast cancer remains a worldwide public-health issue. Novel drugs that increase the sensitivity and reduce the toxic side effects of chemotherapeutic agents are urgently required. The present study investigated the effect and mechanism of the short-term intermittent administration of an anticancer bioactive peptide (...

journal_title：Experimental and therapeutic medicine

authors： Li X,Gao B,Su X

更新日期：2020-09-01 00:00:00

abstract：:Paraneoplastic autoimmune multiorgan syndrome (PAMS), also known as paraneoplasic pemphigus, involves the skin, internal organs and mucosa. PAMS-associated mortality may occur as a result of autoantibody formation against internal tumors and their infiltration into organs other than the skin lesions that characterize ...

journal_title：Experimental and therapeutic medicine

authors： Lee SY,Kim JH,Cho DH

更新日期：2016-09-01 00:00:00

abstract：:Uterine carcinosarcoma (UCS) is a rare but very aggressive cancer of the female reproductive tract with an extremely poor prognosis. With the goal of understanding the role of microRNA (miRNA) dysregulation in these tumors, we profiled the expression of 667 human miRNAs in a panel of eight UCS patients and five benign...

journal_title：Experimental and therapeutic medicine

authors： Devor EJ,DE Mik JN,Ramachandran S,Goodheart MJ,Leslie KK

更新日期：2012-04-01 00:00:00