Comparative genomics of the wheat fungal pathogen Pyrenophora tritici-repentis reveals chromosomal variations and genome plasticity.

Abstract:

BACKGROUND:Pyrenophora tritici-repentis (Ptr) is a necrotrophic fungal pathogen that causes the major wheat disease, tan spot. We set out to provide essential genomics-based resources in order to better understand the pathogenicity mechanisms of this important pathogen. RESULTS:Here, we present eight new Ptr isolate genomes, assembled and annotated; representing races 1, 2 and 5, and a new race. We report a high quality Ptr reference genome, sequenced by PacBio technology with Illumina paired-end data support and optical mapping. An estimated 98% of the genome coverage was mapped to 10 chromosomal groups, using a two-enzyme hybrid approach. The final reference genome was 40.9 Mb and contained a total of 13,797 annotated genes, supported by transcriptomic and proteogenomics data sets. CONCLUSIONS:Whole genome comparative analysis revealed major chromosomal segmental rearrangements and fusions, highlighting intraspecific genome plasticity in this species. Furthermore, the Ptr race classification was not supported at the whole genome level, as phylogenetic analysis did not cluster the ToxA producing isolates. This expansion of available Ptr genomics resources will directly facilitate research aimed at controlling tan spot disease.

journal_name

BMC Genomics

journal_title

BMC genomics

authors

Moolhuijzen P,See PT,Hane JK,Shi G,Liu Z,Oliver RP,Moffat CS

doi

10.1186/s12864-018-4680-3

subject

Has Abstract

pub_date

2018-04-23 00:00:00

pages

279

issue

1

issn

1471-2164

pii

10.1186/s12864-018-4680-3

journal_volume

19

pub_type

杂志文章
  • A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production.

    abstract:BACKGROUND:Succinate is produced petrochemically from maleic anhydride to satisfy a small specialty chemical market. If succinate could be produced fermentatively at a price competitive with that of maleic anhydride, though, it could replace maleic anhydride as the precursor of many bulk chemicals, transforming a multi...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-11-680

    authors: McKinlay JB,Laivenieks M,Schindler BD,McKinlay AA,Siddaramappa S,Challacombe JF,Lowry SR,Clum A,Lapidus AL,Burkhart KB,Harkins V,Vieille C

    更新日期:2010-11-30 00:00:00

  • Transcriptome analysis of Sacha Inchi (Plukenetia volubilis L.) seeds at two developmental stages.

    abstract:BACKGROUND:Sacha Inchi (Plukenetia volubilis L., Euphorbiaceae) is a potential oilseed crop because the seeds of this plant are rich in unsaturated fatty acids (FAs). In particular, the fatty acid composition of its seed oil differs markedly in containing large quantities of α-linolenic acid (18C:3, a kind of ω-3 FAs)....

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-13-716

    authors: Wang X,Xu R,Wang R,Liu A

    更新日期:2012-12-20 00:00:00

  • Treatment-independent miRNA signature in blood of Wilms tumor patients.

    abstract:BACKGROUND:Blood-born miRNA signatures have recently been reported for various tumor diseases. Here, we compared the miRNA signature in Wilms tumor patients prior and after preoperative chemotherapy according to SIOP protocol 2001. RESULTS:We did not find a significant difference between miRNA signature of both groups...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-13-379

    authors: Schmitt J,Backes C,Nourkami-Tutdibi N,Leidinger P,Deutscher S,Beier M,Gessler M,Graf N,Lenhof HP,Keller A,Meese E

    更新日期:2012-08-07 00:00:00

  • Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks.

    abstract:BACKGROUND:Pekin duck products have become popular in Asia over recent decades and account for an increasing market share. However, the genetic mechanisms affecting carcass growth in Pekin ducks remain unknown. This study aimed to identify quantitative trait loci affecting body size and carcass yields in Pekin ducks. ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-018-5379-1

    authors: Deng MT,Zhu F,Yang YZ,Yang FX,Hao JP,Chen SR,Hou ZC

    更新日期:2019-01-03 00:00:00

  • Identification and evolutionary analysis of the nucleolar proteome of Giardia lamblia.

    abstract:BACKGROUND:The nucleoli, including their proteomes, of higher eukaryotes have been extensively studied, while few studies about the nucleoli of the lower eukaryotes - protists were reported. Giardia lamblia, a protist with the controversy of whether it is an extreme primitive eukaryote or just a highly evolved parasite...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-020-6679-9

    authors: Feng JM,Yang CL,Tian HF,Wang JX,Wen JF

    更新日期:2020-03-30 00:00:00

  • An unbiased approach to identify genes involved in development in a turtle with temperature-dependent sex determination.

    abstract:BACKGROUND:Many reptiles exhibit temperature-dependent sex determination (TSD). The initial cue in TSD is incubation temperature, unlike genotypic sex determination (GSD) where it is determined by the presence of specific alleles (or genetic loci). We used patterns of gene expression to identify candidates for genes wi...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-13-308

    authors: Chojnowski JL,Braun EL

    更新日期:2012-07-15 00:00:00

  • Evaluation of viral genome assembly and diversity estimation in deep metagenomes.

    abstract:BACKGROUND:Viruses have unique properties, small genome and regions of high similarity, whose effects on metagenomic assemblies have not been characterized so far. This study uses diverse in silico simulated viromes to evaluate how extensively genomes can be assembled using different sequencing platforms and assemblers...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-989

    authors: Aguirre de Cárcer D,Angly FE,Alcamí A

    更新日期:2014-11-18 00:00:00

  • Expression profile of genes regulated by activity of the Na-H exchanger NHE1.

    abstract:BACKGROUND:In mammalian cells changes in intracellular pH (pHi), which are predominantly controlled by activity of plasma membrane ion exchangers, regulate a diverse range of normal and pathological cellular processes. How changes in pHi affect distinct cellular processes has primarily been determined by evaluating pro...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-5-46

    authors: Putney LK,Barber DL

    更新日期:2004-07-16 00:00:00

  • The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains.

    abstract:BACKGROUND:Due to the predominant usage of short-read sequencing to date, most bacterial genome sequences reported in the last years remain at the draft level. This precludes certain types of analyses, such as the in-depth analysis of genome plasticity. RESULTS:Here we report the finalized genome sequence of the envir...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-017-4301-6

    authors: Pfeiffer F,Zamora-Lagos MA,Blettinger M,Yeroslaviz A,Dahl A,Gruber S,Habermann BH

    更新日期:2018-01-05 00:00:00

  • The nuclear and mitochondrial genomes of Frieseomelitta varia - a highly eusocial stingless bee (Meliponini) with a permanently sterile worker caste.

    abstract:BACKGROUND:Most of our understanding on the social behavior and genomics of bees and other social insects is centered on the Western honey bee, Apis mellifera. The genus Apis, however, is a highly derived branch comprising less than a dozen species, four of which genomically characterized. In contrast, for the equally ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-020-06784-8

    authors: de Paula Freitas FC,Lourenço AP,Nunes FMF,Paschoal AR,Abreu FCP,Barbin FO,Bataglia L,Cardoso-Júnior CAM,Cervoni MS,Silva SR,Dalarmi F,Del Lama MA,Depintor TS,Ferreira KM,Gória PS,Jaskot MC,Lago DC,Luna-Lucena D,Moda L

    更新日期:2020-06-03 00:00:00

  • Comparative transcriptomics of early petal development across four diverse species of Aquilegia reveal few genes consistently associated with nectar spur development.

    abstract:BACKGROUND:Petal nectar spurs, which facilitate pollination through animal attraction and pollen placement, represent a key innovation promoting diversification in the genus Aquilegia (Ranunculaceae). Identifying the genetic components that contribute to the development of these three-dimensional structures will inform...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-6002-9

    authors: Ballerini ES,Kramer EM,Hodges SA

    更新日期:2019-08-22 00:00:00

  • Evolutionary relationships between miRNA genes and their activity.

    abstract:BACKGROUND:The emergence of vertebrates is characterized by a strong increase in miRNA families. MicroRNAs interact broadly with many transcripts, and the evolution of such a system is intriguing. However, evolutionary questions concerning the origin of miRNA genes and their subsequent evolution remain unexplained. RE...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-13-718

    authors: Zhu Y,Skogerbø G,Ning Q,Wang Z,Li B,Yang S,Sun H,Li Y

    更新日期:2012-12-22 00:00:00

  • Integrative analysis of transcriptomic data related to the liver of laying hens: from physiological basics to newly identified functions.

    abstract:BACKGROUND:At sexual maturity, the liver of laying hens undergoes many metabolic changes to support vitellogenesis. In published transcriptomic approaches, hundreds of genes were reported to be overexpressed in laying hens and functional gene annotation using gene ontology tools have essentially revealed an enrichment ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-6185-0

    authors: Gloux A,Duclos MJ,Brionne A,Bourin M,Nys Y,Réhault-Godbert S

    更新日期:2019-11-07 00:00:00

  • Repeats and EST analysis for new organisms.

    abstract:BACKGROUND:Repeat masking is an important step in the EST analysis pipeline. For new species, genomic knowledge is scarce and good repeat libraries are typically unavailable. In these cases it is common practice to mask against known repeats from other species (i.e., model organisms). There are few studies that investi...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-9-23

    authors: Malde K,Jonassen I

    更新日期:2008-01-18 00:00:00

  • Characterization of human plasma-derived exosomal RNAs by deep sequencing.

    abstract:BACKGROUND:Exosomes, endosome-derived membrane microvesicles, contain specific RNA transcripts that are thought to be involved in cell-cell communication. These RNA transcripts have great potential as disease biomarkers. To characterize exosomal RNA profiles systemically, we performed RNA sequencing analysis using thre...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-14-319

    authors: Huang X,Yuan T,Tschannen M,Sun Z,Jacob H,Du M,Liang M,Dittmar RL,Liu Y,Liang M,Kohli M,Thibodeau SN,Boardman L,Wang L

    更新日期:2013-05-10 00:00:00

  • A study of inter-lab and inter-platform agreement of DNA microarray data.

    abstract::As gene expression profile data from DNA microarrays accumulate rapidly, there is a natural need to compare data across labs and platforms. Comparisons of microarray data can be quite challenging due to data complexity and variability. Different labs may adopt different technology platforms. One may ask about the degr...

    journal_title:BMC genomics

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2164-6-71

    authors: Wang H,He X,Band M,Wilson C,Liu L

    更新日期:2005-05-11 00:00:00

  • GWAS and fine-mapping of livability and six disease traits in Holstein cattle.

    abstract:BACKGROUND:Health traits are of significant economic importance to the dairy industry due to their effects on milk production and associated treatment costs. Genome-wide association studies (GWAS) provide a means to identify associated genomic variants and thus reveal insights into the genetic architecture of complex t...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-020-6461-z

    authors: Freebern E,Santos DJA,Fang L,Jiang J,Parker Gaddis KL,Liu GE,VanRaden PM,Maltecca C,Cole JB,Ma L

    更新日期:2020-01-13 00:00:00

  • Acquisition of genome information from single-celled unculturable organisms (radiolaria) by exploiting genome profiling (GP).

    abstract:BACKGROUND:There is no effective method to obtain genome information from single-celled unculturable organisms such as radiolarians. Even worse, such organisms are often very difficult to collect. Sequence analysis of 18S rDNA has been carried out, but obtaining the data has been difficult and it has provided a rather ...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-7-135

    authors: Kouduka M,Matuoka A,Nishigaki K

    更新日期:2006-06-02 00:00:00

  • Conservation of polypyrimidine tract binding proteins and their putative target RNAs in several storage root crops.

    abstract:BACKGROUND:Polypyrimidine-tract binding proteins (PTBs) are ubiquitous RNA-binding proteins in plants and animals that play diverse role in RNA metabolic processes. PTB proteins bind to target RNAs through motifs rich in cytosine/uracil residues to fine-tune transcript metabolism. Among tuber and root crops, potato has...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-018-4502-7

    authors: Kondhare KR,Kumar A,Hannapel DJ,Banerjee AK

    更新日期:2018-02-07 00:00:00

  • Genome-wide association mapping of resistance to a Brazilian isolate of Sclerotinia sclerotiorum in soybean genotypes mostly from Brazil.

    abstract:BACKGROUND:Sclerotinia Stem Rot (SSR), caused by the fungal pathogen Sclerotinia sclerotiorum, is ubiquitous in cooler climates where soybean crops are grown. Breeding for resistance to SSR remains challenging in crops like soybean, where no single gene provides strong resistance, but instead, multiple genes work toget...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-017-4160-1

    authors: Wei W,Mesquita ACO,Figueiró AA,Wu X,Manjunatha S,Wickland DP,Hudson ME,Juliatti FC,Clough SJ

    更新日期:2017-11-07 00:00:00

  • Evolution of cis- and trans-regulatory divergence in the chicken genome between two contrasting breeds analyzed using three tissue types at one-day-old.

    abstract:BACKGROUND:Gene expression variation is a key underlying factor influencing phenotypic variation, and can occur via cis- or trans-regulation. To understand the role of cis- and trans-regulatory variation on population divergence in chicken, we developed reciprocal crosses of two chicken breeds, White Leghorn and Cornis...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-6342-5

    authors: Wang Q,Jia Y,Wang Y,Jiang Z,Zhou X,Zhang Z,Nie C,Li J,Yang N,Qu L

    更新日期:2019-12-05 00:00:00

  • Developing high throughput genotyped chromosome segment substitution lines based on population whole-genome re-sequencing in rice (Oryza sativa L.).

    abstract:BACKGROUND:Genetic populations provide the basis for a wide range of genetic and genomic studies and have been widely used in genetic mapping, gene discovery and genomics-assisted breeding. Chromosome segment substitution lines (CSSLs) are the most powerful tools for the detection and precise mapping of quantitative tr...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-11-656

    authors: Xu J,Zhao Q,Du P,Xu C,Wang B,Feng Q,Liu Q,Tang S,Gu M,Han B,Liang G

    更新日期:2010-11-24 00:00:00

  • Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes.

    abstract:BACKGROUND:The orphan nuclear receptor TR4 (human testicular receptor 4 or NR2C2) plays a pivotal role in a variety of biological and metabolic processes. With no known ligand and few known target genes, the mode of TR4 function was unclear. RESULTS:We report the first genome-wide identification and characterization o...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-11-689

    authors: O'Geen H,Lin YH,Xu X,Echipare L,Komashko VM,He D,Frietze S,Tanabe O,Shi L,Sartor MA,Engel JD,Farnham PJ

    更新日期:2010-12-02 00:00:00

  • Gene regulation of Sclerotinia sclerotiorum during infection of Glycine max: on the road to pathogenesis.

    abstract:BACKGROUND:Sclerotinia sclerotiorum is a broad-host range necrotrophic pathogen which is the causative agent of Sclerotinia stem rot (SSR), and a major disease of soybean (Glycine max). A time course transcriptomic analysis was performed in both compatible and incompatible soybean lines to identify pathogenicity and de...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/s12864-019-5517-4

    authors: Westrick NM,Ranjan A,Jain S,Grau CR,Smith DL,Kabbage M

    更新日期:2019-02-26 00:00:00

  • Accumulation of interspersed and sex-specific repeats in the non-recombining region of papaya sex chromosomes.

    abstract:BACKGROUND:The papaya Y chromosome has undergone a degenerative expansion from its ancestral autosome, as a consequence of recombination suppression in the sex determining region of the sex chromosomes. The non-recombining feature led to the accumulation of repetitive sequences in the male- or hermaphrodite-specific re...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-335

    authors: Na JK,Wang J,Ming R

    更新日期:2014-05-04 00:00:00

  • ArachnoServer: a database of protein toxins from spiders.

    abstract:BACKGROUND:Venomous animals incapacitate their prey using complex venoms that can contain hundreds of unique protein toxins. The realisation that many of these toxins may have pharmaceutical and insecticidal potential due to their remarkable potency and selectivity against target receptors has led to an explosion in th...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-10-375

    authors: Wood DL,Miljenović T,Cai S,Raven RJ,Kaas Q,Escoubas P,Herzig V,Wilson D,King GF

    更新日期:2009-08-13 00:00:00

  • Unlocking the bovine genome.

    abstract::The draft genome sequence of cattle (Bos taurus) has now been analyzed by the Bovine Genome Sequencing and Analysis Consortium and the Bovine HapMap Consortium, which together represent an extensive collaboration involving more than 300 scientists from 25 different countries. ...

    journal_title:BMC genomics

    pub_type: 社论

    doi:10.1186/1471-2164-10-193

    authors: Tellam RL,Lemay DG,Van Tassell CP,Lewin HA,Worley KC,Elsik CG

    更新日期:2009-04-24 00:00:00

  • A database of circadian and diel rhythmic gene expression in the yellow fever mosquito Aedes aegypti.

    abstract:BACKGROUND:The mosquito species Aedes aegypti is the primary vector of many arboviral diseases, including dengue and yellow fevers, that are responsible for a large worldwide health burden. The biological rhythms of mosquitoes regulate many of the physiological processes and behaviors that influence the transmission of...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-1128

    authors: Leming MT,Rund SS,Behura SK,Duffield GE,O'Tousa JE

    更新日期:2014-12-17 00:00:00

  • Major aging-associated RNA expressions change at two distinct age-positions.

    abstract:BACKGROUND:Genome-wide expression profiles are altered during biological aging and can describe molecular regulation of tissue degeneration. Age-regulated mRNA expression trends from cross-sectional studies could describe how aging progresses. We developed a novel statistical methodology to identify age-regulated expre...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-15-132

    authors: Gheorghe M,Snoeck M,Emmerich M,Bäck T,Goeman JJ,Raz V

    更新日期:2014-02-14 00:00:00

  • Population-based rare variant detection via pooled exome or custom hybridization capture with or without individual indexing.

    abstract:BACKGROUND:Rare genetic variation in the human population is a major source of pathophysiological variability and has been implicated in a host of complex phenotypes and diseases. Finding disease-related genes harboring disparate functional rare variants requires sequencing of many individuals across many genomic regio...

    journal_title:BMC genomics

    pub_type: 杂志文章

    doi:10.1186/1471-2164-13-683

    authors: Ramos E,Levinson BT,Chasnoff S,Hughes A,Young AL,Thornton K,Li A,Vallania FL,Province M,Druley TE

    更新日期:2012-12-06 00:00:00