A study of inter-lab and inter-platform agreement of DNA microarray data.

abstract：BACKGROUND:Cytochrome P450s (CYPs) in animals fall into two categories: those that synthesize or metabolize endogenous molecules and those that interact with exogenous chemicals from the diet or the environment. The latter form a critical component of detoxification systems. RESULTS:Data mining and manual curation of ...

journal_title：BMC genomics

authors： Baldwin WS,Marko PB,Nelson DR

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:Meiotic recombination is a fundamental evolutionary process. It not only generates diversity, but influences the efficacy of natural selection and genome evolution. There can be significant heterogeneity in recombination rates within and between species, however this variation is not well understood outside ...

journal_title：BMC genomics

authors： Gion JM,Hudson CJ,Lesur I,Vaillancourt RE,Potts BM,Freeman JS

更新日期：2016-08-09 00:00:00

abstract：BACKGROUND:Macrosatellites are some of the largest variable number tandem repeats in the human genome, but what role these unusual sequences perform is unknown. Their importance to human health is clearly demonstrated by the 4q35 macrosatellite D4Z4 that is associated with the onset of the muscle degenerative disease f...

journal_title：BMC genomics

authors： Tremblay DC,Alexander G Jr,Moseley S,Chadwick BP

更新日期：2010-11-15 00:00:00

abstract：BACKGROUND:Cucumber, Cucumis sativus L. (2n = 2 × = 14) and melon, C. melo L. (2n = 2 × = 24) are two important vegetable species in the genus Cucumis (family Cucurbitaceae). Both species have an Asian origin that diverged approximately nine million years ago. Cucumber is believed to have evolved from melon through chr...

journal_title：BMC genomics

authors： Li D,Cuevas HE,Yang L,Li Y,Garcia-Mas J,Zalapa J,Staub JE,Luan F,Reddy U,He X,Gong Z,Weng Y

更新日期：2011-08-05 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are short non-coding RNAs that are emerging as important post-transcriptional regulators of neuronal and synaptic development. The precise impact of miRNAs on presynaptic function and neurotransmission remains, however, poorly understood. RESULTS:Here, we identify miR-27b-an abundant neur...

journal_title：BMC genomics

authors： Poon VY,Gu M,Ji F,VanDongen AM,Fivaz M

更新日期：2016-10-04 00:00:00

abstract：BACKGROUND:Mango fruits contain a broad spectrum of phenolic compounds which impart potential health benefits; their biosynthesis is catalysed by enzymes in the phenylpropanoid-flavonoid (PF) pathway. The aim of this study was to reveal the variability in genes involved in the PF pathway in three different mango variet...

journal_title：BMC genomics

authors： Hoang VL,Innes DJ,Shaw PN,Monteith GR,Gidley MJ,Dietzgen RG

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:BAC-based physical maps provide for sequencing across an entire genome or a selected sub-genomic region of biological interest. Such a region can be approached with next-generation whole-genome sequencing and assembly as if it were an independent small genome. Using the minimum tiling path as a guide, specif...

journal_title：BMC genomics

authors： Feltus FA,Saski CA,Mockaitis K,Haiminen N,Parida L,Smith Z,Ford J,Staton ME,Ficklin SP,Blackmon BP,Cheng CH,Schnell RJ,Kuhn DN,Motamayor JC

更新日期：2011-07-27 00:00:00

abstract：BACKGROUND:Since 2007, bacterial canker caused by Pseudomonas syringae pv. actinidiae (Psa) has become a pandemic disease leading to important economic losses in every country where kiwifruit is widely cultivated. Options for controlling this disease are very limited and rely primarily on the use of bactericidal compou...

journal_title：BMC genomics

authors： Michelotti V,Lamontanara A,Buriani G,Orrù L,Cellini A,Donati I,Vanneste JL,Cattivelli L,Tacconi G,Spinelli F

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:Vinyl chloride is a widespread groundwater pollutant and Group 1 carcinogen. A previous comparative genomic analysis revealed that the vinyl chloride reductase operon, vcrABC, of Dehalococcoides sp. strain VS is embedded in a horizontally-acquired genomic island that integrated at the single-copy tmRNA gene,...

journal_title：BMC genomics

authors： McMurdie PJ,Hug LA,Edwards EA,Holmes S,Spormann AM

更新日期：2011-06-02 00:00:00

abstract：BACKGROUND:The freshwater snail Lymnaea stagnalis (L. stagnalis) has served as a successful model for studies in the field of Neuroscience. However, a serious drawback in the molecular analysis of the nervous system of L. stagnalis has been the lack of large-scale genomic or neuronal transcriptome information, thereby ...

journal_title：BMC genomics

authors： Feng ZP,Zhang Z,van Kesteren RE,Straub VA,van Nierop P,Jin K,Nejatbakhsh N,Goldberg JI,Spencer GE,Yeoman MS,Wildering W,Coorssen JR,Croll RP,Buck LT,Syed NI,Smit AB

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to develop holistic effects characterizations for the wildlife bird model, Northern bobwhite (Colinus virginianus) dosed with the explosives degradation product 2-amino-4,6-dinitrotoluene (2A-DNT)....

journal_title：BMC genomics

authors： Gust KA,Nanduri B,Rawat A,Wilbanks MS,Ang CY,Johnson DR,Pendarvis K,Chen X,Quinn MJ Jr,Johnson MS,Burgess SC,Perkins EJ

更新日期：2015-08-07 00:00:00

abstract：BACKGROUND:The unisexual Amazon molly (Poecilia formosa) originated from a hybridization between two sexual species, the sailfin molly (Poecilia latipinna) and the Atlantic molly (Poecilia mexicana). The Amazon molly reproduces clonally via sperm-dependent parthenogenesis (gynogenesis), in which the sperm of closely re...

journal_title：BMC genomics

authors： Schedina IM,Groth D,Schlupp I,Tiedemann R

更新日期：2018-01-03 00:00:00

abstract：BACKGROUND:Molecular mechanisms underlying coral larval competence, the ability of larvae to respond to settlement cues, determine their dispersal potential and are potential targets of natural selection. Here, we profiled competence, fluorescence and genome-wide gene expression in embryos and larvae of the reef-buildi...

journal_title：BMC genomics

authors： Strader ME,Aglyamova GV,Matz MV

更新日期：2018-01-04 00:00:00

abstract：BACKGROUND:Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a respiratory disease which causes great economic losses worldwide. Many virulence factors are involved in the pathogenesis, namely capsular polysaccharides, RTX toxins, LPS and many iron acquisition systems. In order to ide...

journal_title：BMC genomics

authors： Deslandes V,Denicourt M,Girard C,Harel J,Nash JH,Jacques M

更新日期：2010-02-08 00:00:00

abstract：BACKGROUND:Chromosome 17q21.31 contains a common inversion polymorphism of approximately 900 kb in populations with European ancestry. Two divergent MAPT haplotypes, H1 and H2 are described with distinct linkage disequilibrium patterns across the region reflecting the inversion status at this locus. The MAPT H1 haploty...

journal_title：BMC genomics

authors： de Jong S,Chepelev I,Janson E,Strengman E,van den Berg LH,Veldink JH,Ophoff RA

更新日期：2012-09-06 00:00:00

abstract：BACKGROUND:Lipopolysaccharide (LPS) from Gram-negative bacteria cause innate immune responses in animals and plants. The molecules involved in LPS signaling in animals are well studied, whereas those in plants are not yet as well documented. Recently, we identified Arabidopsis AtLBR-2, which binds to LPS from Pseudomon...

journal_title：BMC genomics

authors： Iizasa S,Iizasa E,Watanabe K,Nagano Y

更新日期：2017-12-29 00:00:00

abstract：BACKGROUND:The recently developed RNA interference (RNAi) technology has created an unprecedented opportunity which allows the function of individual genes in whole organisms or cell lines to be interrogated at genome-wide scale. However, multiple issues, such as off-target effects or low efficacies in knocking down ce...

journal_title：BMC genomics

authors： Wang L,Tu Z,Sun F

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression by targeting specific mRNA species for degradation or interfering with translation. Specific miRNAs are key regulators of adipogenesis, and are expressed at different levels in adipose tissue from lean and obese mice. The deg...

journal_title：BMC genomics

authors： Link JC,Hasin-Brumshtein Y,Cantor RM,Chen X,Arnold AP,Lusis AJ,Reue K

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:The capacity of European pear fruit (Pyrus communis L.) to ripen after harvest develops during the final stages of growth on the tree. The objective of this study was to characterize changes in 'Bartlett' pear fruit physico-chemical properties and transcription profiles during fruit maturation leading to att...

journal_title：BMC genomics

authors： Nham NT,de Freitas ST,Macnish AJ,Carr KM,Kietikul T,Guilatco AJ,Jiang CZ,Zakharov F,Mitcham EJ

更新日期：2015-10-09 00:00:00

abstract：BACKGROUND:In recent years, dozens of Arabidopsis and rice CCCH-type zinc finger genes have been functionally studied, many of which confer important traits, such as abiotic and biotic stress tolerance, delayed leaf senescence and improved plant architecture. Switchgrass (Panicum virgatum) is an important bioenergy cro...

journal_title：BMC genomics

authors： Yuan S,Xu B,Zhang J,Xie Z,Cheng Q,Yang Z,Cai Q,Huang B

更新日期：2015-02-25 00:00:00

abstract：BACKGROUND:The ability to rapidly map millions of oligonucleotide fragments to a reference genome is crucial to many high throughput genomic technologies. RESULTS:We propose an intuitive and efficient algorithm, titled extreme MApping of OligoNucleotide (xMAN), to rapidly map millions of oligonucleotide fragments to a...

journal_title：BMC genomics

authors： Li W,Carroll JS,Brown M,Liu xS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Candida albicans is a diploid pathogenic fungus not yet amenable to routine genetic investigations. Understanding aspects of the regulation of its biological functions and the assembly of its protein complexes would lead to further insight into the biology of this common disease-causing microbial agent. RES...

journal_title：BMC genomics

authors： Lavoie H,Sellam A,Askew C,Nantel A,Whiteway M

更新日期：2008-12-02 00:00:00

abstract：BACKGROUND:Flammulina filiformis (previously known as Asian F. velutipes) is a popular commercial edible mushroom. Many bioactive compounds with medicinal effects, such as polysaccharides and sesquiterpenoids, have been isolated and identified from F. filiformis, but their biosynthesis and regulation at the molecular l...

journal_title：BMC genomics

authors： Chen J,Li JM,Tang YJ,Ma K,Li B,Zeng X,Liu XB,Li Y,Yang ZL,Xu WN,Xie BG,Liu HW,Guo SX

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:Due to the predominant usage of short-read sequencing to date, most bacterial genome sequences reported in the last years remain at the draft level. This precludes certain types of analyses, such as the in-depth analysis of genome plasticity. RESULTS:Here we report the finalized genome sequence of the envir...

journal_title：BMC genomics

authors： Pfeiffer F,Zamora-Lagos MA,Blettinger M,Yeroslaviz A,Dahl A,Gruber S,Habermann BH

更新日期：2018-01-05 00:00:00

abstract：BACKGROUND:Deep-sea hydrothermal vents are unique chemoautotrophic ecosystems with harsh conditions. Alvinocaris longirostris is one of the dominant crustacean species inhabiting in these extreme environments. It is significant to clarify mechanisms in their adaptation to the vents. Lysine acetylation has been known to...

journal_title：BMC genomics

authors： Hui M,Cheng J,Sha Z

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:A key developmental transformation in the life of all vertebrates is the transition to sexual maturity, whereby individuals are capable of reproducing for the first time. In the farming of Atlantic salmon, early maturation prior to harvest size has serious negative production impacts. RESULTS:We report geno...

journal_title：BMC genomics

authors： Mohamed AR,Verbyla KL,Al-Mamun HA,McWilliam S,Evans B,King H,Kube P,Kijas JW

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:Ralstonia solanacearum is an important plant pathogen. The genome of R. solananearum GMI1000 is organised into two replicons (a 3.7-Mb chromosome and a 2.1-Mb megaplasmid) and this bipartite genome structure is characteristic for most R. solanacearum strains. To determine whether the megaplasmid was acquired...

journal_title：BMC genomics

authors： Coenye T,Vandamme P

更新日期：2003-03-17 00:00:00

abstract：BACKGROUND:Poxviruses constitute one of the largest and most complex animal virus families known. The notorious smallpox disease has been eradicated and the virus contained, but its simian sister, monkeypox is an emerging, untreatable infectious disease, killing 1 to 10 % of its human victims. In the case of poxviruses...

journal_title：BMC genomics

authors： Zhao K,Wohlhueter RM,Li Y

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:The Cleavage Stimulation Factor (CstF) is a required protein complex for eukaryotic mRNA 3'-processing. CstF interacts with 3'-processing downstream elements (DSEs) through its 64-kDa subunit, CstF-64; however, the exact nature of this interaction has remained unclear. We used EST-to-genome alignments to ide...

journal_title：BMC genomics

authors： Salisbury J,Hutchison KW,Graber JH

更新日期：2006-03-16 00:00:00

abstract：BACKGROUND:Incilaria (= Meghimatium) fruhstorferi is an air-breathing land slug found in restricted habitats of Japan, Taiwan and selected provinces of South Korea (Jeju, Chuncheon, Busan, and Deokjeokdo). The species is on a decline due to depletion of forest cover, predation by natural enemies, and collection. To fac...

journal_title：BMC genomics

authors： Patnaik BB,Chung JM,Hwang HJ,Sang MK,Park JE,Min HR,Cho HC,Dewangan N,Baliarsingh S,Kang SW,Park SY,Jo YH,Park HS,Kim WJ,Han YS,Lee JS,Lee YS

更新日期：2019-02-26 00:00:00