Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks.

abstract：BACKGROUND:Leishmaniasis is a neglected tropical disease with diverse clinical phenotypes, determined by parasite, host and vector interactions. Despite the advances in molecular biology and the availability of more Leishmania genome references in recent years, the association between parasite species and distinct clin...

journal_title：BMC genomics

authors： Samarasinghe SR,Samaranayake N,Kariyawasam UL,Siriwardana YD,Imamura H,Karunaweera ND

更新日期：2018-11-28 00:00:00

abstract：BACKGROUND:Understanding syntentic relationship between two species is critical to assessing the potential for comparative genomic analysis. Common bean (Phaseolus vulgaris L.) and soybean (Glycine max L.), the two most important members of the Phaseoleae legumes, appear to have a diploid and polyploidy recent past, re...

journal_title：BMC genomics

authors： McClean PE,Mamidi S,McConnell M,Chikara S,Lee R

更新日期：2010-03-18 00:00:00

abstract：BACKGROUND:Short non-coding RNAs (ncRNAs) perform their cellular functions in ribonucleoprotein (RNP) complexes, which are also essential for maintaining the stability of the ncRNAs. Depletion of individual protein components of non-coding ribonucleoprotein (ncRNP) particles by RNA interference (RNAi) may therefore aff...

journal_title：BMC genomics

authors： Aftab MN,He H,Skogerbø G,Chen R

更新日期：2008-06-11 00:00:00

abstract：BACKGROUND:Small untranslated RNAs (sRNAs) seem to be far more abundant than previously believed. The number of sRNAs confirmed in E. coli through various approaches is above 70, with several hundred more sRNA candidate genes under biological validation. Although the total number of sRNAs in any one species is still un...

journal_title：BMC genomics

authors： Ulvé VM,Sevin EW,Chéron A,Barloy-Hubler F

更新日期：2007-12-19 00:00:00

abstract：BACKGROUND:Aquaporins (AQPs), as members of the major intrinsic protein (MIP) superfamily, facilitated the permeation of water and other solutes and are involved in multiple biological processes. AQP family exists in almost all living organisms and is highly diversified in vertebrates in both classification and functio...

journal_title：BMC genomics

authors： Jia Y,Liu X

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:With the advance of new massively parallel genotyping technologies, quantitative trait loci (QTL) fine mapping and map-based cloning become more achievable in identifying genes for important and complex traits. Development of high-density genetic markers in the QTL regions of specific mapping populations is ...

journal_title：BMC genomics

authors： Wu X,Ren C,Joshi T,Vuong T,Xu D,Nguyen HT

更新日期：2010-08-11 00:00:00

abstract：BACKGROUND:Aspergillus arachidicola is an aflatoxigenic fungal species, first isolated from the leaves of a wild peanut species native to Argentina. It has since been reported in maize, Brazil nut and human sputum samples. This aflatoxigenic species is capable of secreting both B and G aflatoxins, similar to A. parasit...

journal_title：BMC genomics

authors： Moore GG,Mack BM,Beltz SB,Puel O

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:microRNA (miRNA) expression plays an influential role in cancer classification and malignancy, and miRNAs are feasible as alternative diagnostic markers for pancreatic cancer, a highly aggressive neoplasm with silent early symptoms, high metastatic potential, and resistance to conventional therapies. METHOD...

journal_title：BMC genomics

authors： Kwon MS,Kim Y,Lee S,Namkung J,Yun T,Yi SG,Han S,Kang M,Kim SW,Jang JY,Park T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-number profile (CNP) of a set of genes in a genome. Our aim is to compute the evolutionary distance b...

journal_title：BMC genomics

authors： Cordonnier G,Lafond M

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:The mosquito Anopheles gambiae is a major vector of human malaria. Increasing evidence indicates that blood cells (hemocytes) comprise an essential arm of the mosquito innate immune response against both bacteria and malaria parasites. To further characterize the role of hemocytes in mosquito immunity, we un...

journal_title：BMC genomics

authors： Baton LA,Robertson A,Warr E,Strand MR,Dimopoulos G

更新日期：2009-06-05 00:00:00

abstract：BACKGROUND:Two fifths of the world's population is at risk from dengue. The absence of effective drugs and vaccines leaves vector control as the primary intervention tool. Understanding dengue virus (DENV) host interactions is essential for the development of novel control strategies. The availability of genome sequenc...

journal_title：BMC genomics

authors： Guo X,Xu Y,Bian G,Pike AD,Xie Y,Xi Z

更新日期：2010-06-16 00:00:00

abstract：BACKGROUND:Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important human pathogen. Whole genome analysis methods on patient-derived material are thus likely to have a...

journal_title：BMC genomics

authors： Bright AT,Tewhey R,Abeles S,Chuquiyauri R,Llanos-Cuentas A,Ferreira MU,Schork NJ,Vinetz JM,Winzeler EA

更新日期：2012-06-21 00:00:00

abstract：BACKGROUND:The molecular mechanisms that determine the organism's response to a variety of doses and modalities of stress factors are not well understood. RESULTS:We studied effects of ionizing radiation (144, 360 and 864 Gy), entomopathogenic fungus (10 and 100 CFU), starvation (16 h), and cold shock (+4, 0 and -4°C)...

journal_title：BMC genomics

authors： Moskalev A,Zhikrivetskaya S,Krasnov G,Shaposhnikov M,Proshkina E,Borisoglebsky D,Danilov A,Peregudova D,Sharapova I,Dobrovolskaya E,Solovev I,Zemskaya N,Shilova L,Snezhkina A,Kudryavtseva A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Simple Sequence Repeats (SSRs) are widely used in population genetic studies but their classical development is costly and time-consuming. The ever-increasing available DNA datasets generated by high-throughput techniques offer an inexpensive alternative for SSRs discovery. Expressed Sequence Tags (ESTs) hav...

journal_title：BMC genomics

authors： Lopez L,Barreiro R,Fischer M,Koch MA

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:Dermatophytes are the primary causative agent of dermatophytoses, a disease that affects billions of individuals worldwide. Trichophyton rubrum is the most common of the superficial fungi. Although T. rubrum is a recognized pathogen for humans, little is known about how its transcriptional pattern is related...

journal_title：BMC genomics

authors： Wang L,Ma L,Leng W,Liu T,Yu L,Yang J,Yang L,Zhang W,Zhang Q,Dong J,Xue Y,Zhu Y,Xu X,Wan Z,Ding G,Yu F,Tu K,Li Y,Li R,Shen Y,Jin Q

更新日期：2006-10-11 00:00:00

abstract：BACKGROUND:Short-read resequencing of genomes produces abundant information of the genetic variation of individuals. Due to their numerous nature, these variants are rarely exhaustively validated. Furthermore, low levels of undetected variant miscalling will have a systematic and disproportionate impact on the interpre...

journal_title：BMC genomics

authors： Field MA,Burgio G,Chuah A,Al Shekaili J,Hassan B,Al Sukaiti N,Foote SJ,Cook MC,Andrews TD

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder that is clinically defined in terms of motor symptoms. These are preceded by prodromal non-motor manifestations that prove the systemic nature of the disease. Identifying genes and pathways altered in living patients provide new inf...

journal_title：BMC genomics

authors： Calligaris R,Banica M,Roncaglia P,Robotti E,Finaurini S,Vlachouli C,Antonutti L,Iorio F,Carissimo A,Cattaruzza T,Ceiner A,Lazarevic D,Cucca A,Pangher N,Marengo E,di Bernardo D,Pizzolato G,Gustincich S

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:Wood formation affects the chemical and physical properties of wood, and thus affects its utility as a building material or a feedstock for biofuels, pulp and paper. To obtain genome-wide insights on the transcriptome changes and regulatory networks in wood formation, we used high-throughput RNA sequencing t...

journal_title：BMC genomics

authors： Chen J,Chen B,Zhang D

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:Cultivated watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus] is an important agriculture crop world-wide. The fruit of watermelon undergoes distinct stages of development with dramatic changes in its size, color, sweetness, texture and aroma. In order to better understand the genetic and m...

journal_title：BMC genomics

authors： Guo S,Liu J,Zheng Y,Huang M,Zhang H,Gong G,He H,Ren Y,Zhong S,Fei Z,Xu Y

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often share similar ligands. The sequence data provided by the human genome project allows us to identify new GPRs by in silico homology screening, and to predi...

journal_title：BMC genomics

authors： Wittenberger T,Hellebrand S,Munck A,Kreienkamp HJ,Schaller HC,Hampe W

更新日期：2002-07-05 00:00:00

abstract：BACKGROUND:The large amount of data produced by high-throughput sequencing poses new computational challenges. In the last decade, several tools have been developed for the identification of transcription and splicing factor binding sites. RESULTS:Here, we introduce the SeAMotE (Sequence Analysis of Motifs Enrichment)...

journal_title：BMC genomics

authors： Agostini F,Cirillo D,Ponti RD,Tartaglia GG

更新日期：2014-10-23 00:00:00

abstract：BACKGROUND:Soybean (Glycine max (L. Merr.)) resistance to any population of Heterodera glycines (I.), or Fusarium virguliforme (Akoi, O'Donnell, Homma & Lattanzi) required a functional allele at Rhg1/Rfs2. H. glycines, the soybean cyst nematode (SCN) was an ancient, endemic, pest of soybean whereas F. virguliforme caus...

journal_title：BMC genomics

authors： Srour A,Afzal AJ,Blahut-Beatty L,Hemmati N,Simmonds DH,Li W,Liu M,Town CD,Sharma H,Arelli P,Lightfoot DA

更新日期：2012-08-02 00:00:00

abstract：BACKGROUND:Horses have been strongly selected for speed, strength, and endurance-exercise traits since the onset of domestication. As a result, highly specialized horse breeds have developed with many modern horse breeds often representing closed populations with high phenotypic and genetic uniformity. However, a great...

journal_title：BMC genomics

authors： Velie BD,Lillie M,Fegraeus KJ,Rosengren MK,Solé M,Wiklund M,Ihler CF,Strand E,Lindgren G

更新日期：2019-02-04 00:00:00

abstract：BACKGROUND:This paper presents a retrospective statistical study on the newly-released data set by the Stanley Neuropathology Consortium on gene expression in bipolar disorder and schizophrenia. This data set contains gene expression data as well as limited demographic and clinical data for each subject. Previous studi...

journal_title：BMC genomics

authors： Struyf J,Dobrin S,Page D

更新日期：2008-11-07 00:00:00

abstract：BACKGROUND:'Systems-wide' approaches such as microarray RNA-profiling are ideally suited to the study of the complex overlapping responses of plants to biotic and abiotic stresses. However, commercial microarrays are only available for a limited number of plant species and development costs are so substantial as to be ...

journal_title：BMC genomics

authors： Davey MW,Graham NS,Vanholme B,Swennen R,May ST,Keulemans J

更新日期：2009-09-16 00:00:00

abstract：BACKGROUND:Rhesus monkeys (Macaca mulatta) are widely-used as experimental animals in biomedical research and are closely related to other laboratory macaques, such as cynomolgus monkeys (Macaca fascicularis), and to humans, sharing a last common ancestor from about 25 million years ago. Although rhesus monkeys have be...

journal_title：BMC genomics

authors： Kim DS,Huh JW,Kim YH,Park SJ,Lee SR,Chang KT

更新日期：2010-07-12 00:00:00

abstract：BACKGROUND:To generate specific transcript profiles, one must isolate homogenous cell populations using techniques that often yield small amounts of RNA, requiring researchers to employ RNA amplification methods. The data generated by using these methods must be extensively evaluated to determine any technique dependen...

journal_title：BMC genomics

authors： Gold D,Coombes K,Medhane D,Ramaswamy A,Ju Z,Strong L,Koo JS,Kapoor M

更新日期：2004-01-06 00:00:00

abstract：BACKGROUND:Bombyx mori was domesticated from the Chinese wild silkworm, Bombyx mandarina. Wild and domestic silkworms are good models in which to investigate genes related to silk protein synthesis that may be differentially expressed in silk glands, because their silk productions are very different. Here we used the m...

journal_title：BMC genomics

authors： Fang SM,Hu BL,Zhou QZ,Yu QY,Zhang Z

更新日期：2015-02-06 00:00:00

abstract：BACKGROUND:The Brassicaceae family is an exemplary model for studying plant polyploidy. The Brassicaceae knowledge-base includes the well-annotated Arabidopsis thaliana reference sequence; well-established evidence for three rounds of whole genome duplication (WGD); and the conservation of genomic structure, with 24 co...

journal_title：BMC genomics

authors： Kim J,Lee J,Choi JP,Park I,Yang K,Kim MK,Lee YH,Nou IS,Kim DS,Min SR,Park SU,Kim H

更新日期：2014-07-18 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are a large family of endogenous, non-coding RNAs, about 22 nucleotides long, which regulate gene expression through sequence-specific base pairing with target mRNAs. Extensive studies have shown that miRNA expression in the skin changes remarkably during distinct stages of the hair cycle ...

journal_title：BMC genomics

authors： Yuan C,Wang X,Geng R,He X,Qu L,Chen Y

更新日期：2013-07-28 00:00:00