Infantile-onset Pompe disease with neonatal debut: A case report and literature review.

abstract：:Thrombosis are severe complications of paroxysmal nocturnal hemoglobinuria (PNH), effectively reduced by eculizumab. Extracellular vesicles (EVs) may play a central role. The objective of this study was to assess the procoagulant activity of plasma isolated from PNH patients (treated or not by eculizumab) and to quant...

journal_title：Medicine

authors： Devalet B,Wannez A,Bailly N,Alpan L,Gheldof D,Douxfils J,Bihin B,Chatelain B,Dogné JM,Chatelain C,Mullier F

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:High mobility group box 1 (HMGB1) is a kind of proinflammatory mediator to stimulate the innate and adaptive immune system and participates in a number of acute and chronic inflammatory processes after sterile injury or microbial invasion. HMGB1 has been suggested to be involved in the pathogenesis of many a...

journal_title：Medicine

authors： Zhu B,Zhu Q,Li N,Wu T,Liu S,Liu S

更新日期：2018-07-01 00:00:00

abstract：:Strength training has, in recent years, been shown to be beneficial for people with Parkinson disease and multiple sclerosis. Consensus regarding its utility for these disorders nevertheless remains contentious among healthcare professionals. Greater clarity is required, especially in regards to the type and magnitude...

journal_title：Medicine

authors： Cruickshank TM,Reyes AR,Ziman MR

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:JLC has been widely applied as a promising adjunctive drug for GC. However, the exact effects and safety of JLC have yet to be systematically investigated. We aimed to summarize the efficacy and safety of JLC for the treatment of advanced GC through the meta-analysis, in order to provide scientific reference...

journal_title：Medicine

authors： Li J,Han B,Sun G,Zheng Z,Mu Y,Chi J

更新日期：2020-06-05 00:00:00

abstract：:This study aimed to assess the efficacy and safety of bevacizumab plus preoperative chemotherapy as first-line treatment for liver-only metastatic colorectal cancer in Chinese patients compared with those of preoperative chemotherapy alone.Patients with histologically confirmed liver-only metastatic colorectal cancer ...

journal_title：Medicine

authors： Lu ZH,Peng JH,Wang FL,Yuan YF,Jiang W,Li YH,Wu XJ,Chen G,Ding PR,Li LR,Kong LH,Lin JZ,Zhang RX,Wan DS,Pan ZZ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the prognostic implication of asphericity (ASP); spatial irregularity; of pretherapeutic F 2-deoxy-2-fluoro-D-glucose (F FDG) tumor uptake in patients with invasive ductal carcinoma (IDC) of the breast. METHODS:One hundred thirty-one female IDC patients (mean age = 48.1...

journal_title：Medicine

authors： Jung JH,Son SH,Kim DH,Lee J,Jeong SY,Lee SW,Park HY,Lee J,Ahn BC

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:We conducted this study to compare the efficacy and safety of entecavir and tenofovir in the treatment of treatment-naïve HBV e antigen (HBeAg)-positive patients with chronic hepatitis B (CHB) for 144 weeks. METHODS:A total of 320 treatment-naïve HBeAg-positive CHB patients who received randomly a single reg...

journal_title：Medicine

authors： Cai D,Pan C,Yu W,Dang S,Li J,Wu S,Jiang N,Wang M,Zhang Z,Lin F,Xin S,Yang Y,Shen B,Ren H

更新日期：2019-01-01 00:00:00

abstract：:This study aimed to compare various visual function parameters for evaluating the quality of life (QOL) of patients with advanced glaucoma with low vision.In total, 44 eyes of advanced glaucoma patients with low vision were included in this cross-sectional study. A moving pattern edge band program was used to assess e...

journal_title：Medicine

authors： Jeon SJ,Jung Y,Jung CS,Park HL,Park CK

更新日期：2020-02-01 00:00:00

abstract：:Pancreatic cancer (PaCa) is one of the most fatal cancers in the world. Although great efforts have made to explore the mechanisms of PaCa oncogenesis, the prognosis of PaCa patients is still unsatisfactory. Thus, it is imperative to further understand the potential carcinogenesis of PaCa and reliable prognostic model...

journal_title：Medicine

authors： Yang J,Shi W,Zhu S,Yang C

更新日期：2020-09-11 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) is acute renal failure observed after administration of iodinated contrast media during angiographic or other medical procedures. In recent years, many studies have focused on biomarkers that recognize CIN and/or predict its development in advance. One of the many biomarker...

journal_title：Medicine

authors： Jiang J,Ji HY,Xie WM,Ran LS,Chen YS,Zhang CT,Quan XQ

更新日期：2019-08-01 00:00:00

abstract：:The present study compared the efficacy of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and magnetic resonance elastography (MRE) in the estimation of hepatic fibrosis stages with histopathologic correlation.This retrospective study included 104 pa...

journal_title：Medicine

authors： Wu WP,Hoi CI,Chen RC,Lin CP,Chou CT

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:This study aimed to determine the efficacy and safety of extracorporeal shock-wave therapy (ESWT) for treating patients with chronic rotator cuff tendonitis (CRCT). METHODS:In this study, 84 patients with CRCT were randomly divided into intervention and control groups in a ratio of 1:1. Patients in the inte...

journal_title：Medicine

authors： Li W,Zhang SX,Yang Q,Li BL,Meng QG,Guo ZG

更新日期：2017-09-01 00:00:00

abstract：:The objective of this study is to assess the association between levels of empathy and burnout of emergency professionals in all the assistance levels.A cross-sectional observational study was conducted in the health region of Lleida and the Pyrenees with 100 professionals from the field of Urgency. Participation reac...

journal_title：Medicine

authors： Yuguero O,Forné C,Esquerda M,Pifarré J,Abadías MJ,Viñas J

更新日期：2017-09-01 00:00:00

abstract：RATIONALE:Primary diffuse large B-cell lymphoma of the chest wall is extremely rare. A majority of the pleural lymphomas develop in patients with chronic tuberculous pyothorax. The underlying mechanism might be attributed to the sustained stimulation of chronic inflammation. Surgery followed by adjuvant chemotherapy ca...

journal_title：Medicine

authors： Zhang Q,Ju Y,Qu T,Wang T,Liu X

更新日期：2018-11-01 00:00:00

abstract：:Patients with systemic lupus erythematosus have a poor prognosis of pregnancy, since it is associated with significant maternal and fetal morbidity, including spontaneous miscarriage, pre-eclampsia, intrauterine growth restriction, fetal death and pre-term delivery. We report a case with successful pregnancy in a pati...

journal_title：Medicine

authors： de Macedo JF,de Macedo GC,Campos LA,Baltatu OC

更新日期：2015-09-01 00:00:00

abstract：RATIONALE:Achromobacter xylosoxidans infection is mostly reported in immunocompromised patients. Until now, it is still rarely reported in patients undergoing peritoneal dialysis. PATIENT CONCERNS:This is the 1st case of A xylosoxidans infection due to tunnel infection of a Tenckhoff catheter. DIAGNOSIS:The diagnosis...

journal_title：Medicine

authors： Tsai JL,Tsai SF

更新日期：2017-04-01 00:00:00

abstract：:Right ventricular pacing often results in prolonged QRS duration (QRSd) as the result of right ventricular stimulation, and atrial fibrillation (AF) may result. The association of pacing-induced prolonged QRSd and AF in patients with permanent pacemakers is unknown.We selected 180 consecutive patients who underwent pa...

journal_title：Medicine

authors： Xing F,Jiang J,Hu X,Feng C,He J,Dong Y,Ma Y,Tang A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Assessing the effectiveness and safety of Chinese medicine for the mastitis in COVID-19 patients is the main purpose of this systematic review protocol. METHODS:The following electronic databases will be searched from inception to April 2020: MEDLINE, Ovid, EMBASE, the Cochrane Library, the Allied and Compl...

journal_title：Medicine

authors： Wen D,Shi Y,Zhang X,Lv G

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:The potential benefits and safety of hepatic arterial infusion chemotherapy (HAIC) for the treatment of patients with hepatocellular carcinoma (HCC) remains inconsistent. Therefore, we conducted this meta-analysis of evaluate the efficacy and safety of HAIC in the treatment of HCC. METHODS:A comprehensive l...

journal_title：Medicine

authors： Long GB,Xiao CW,Zhao XY,Zhang J,Li X

更新日期：2020-06-26 00:00:00

abstract：OBJECTIVES:To explore that if mid-regional sequence of pro-A-type natriuretic peptide (MR-proANP) may have a good value of diagnosis in heart failure with preserved ejection fraction (HFpEF) compared with N-terminal pro-B-type natriuretic peptide (NT-proBNP). METHODS:Participants with cardiovascular disease who were e...

journal_title：Medicine

authors： Cui K,Huang W,Fan J,Lei H

更新日期：2018-09-01 00:00:00

abstract：:The occurrence and characteristics of remissions in patients with systematic lupus erythematosus (SLE) have not been determined. We therefore studied this in a cohort of 667 patients and found that 156 patients had achieved at least 1 period of 1 year or more of treatment-free clinical remission. This represents an in...

journal_title：Medicine

authors： Drenkard C,Villa AR,Garcia-Padilla C,Pérez-Vázquez ME,Alarcón-Segovia D

更新日期：1996-03-01 00:00:00

abstract：:To study the changes in 3 mutations related with hepatitis B e antigen (HBeAg) in patients with HBeAg-positive chronic hepatitis B (CHB) during interferon therapy.HBeAg seroconversion is a major therapeutic milestone for patients with HBeAg-positive CHB. The precore mutation G1896A and the basal core promoter mutation...

journal_title：Medicine

authors： Geng Y,Wang X,Lu X,Wu X,Xu N,Han L,Xu J

更新日期：2016-02-01 00:00:00

abstract：:The aim of this paper was to evaluate the activity and tolerability of oral vinorelbine in patients with advanced castration resistant prostate cancer (CRPC) who progressed after a minimum of three lines including: abiraterone acetate, docetaxel, cabazitaxel, and enzalutamide.Treatment consisted of weekly oral vinorel...

journal_title：Medicine

authors： Roviello G,Corona SP,Conca R,Petrioli R,Rosellini P,Bonetta A,Aieta M

更新日期：2019-06-01 00:00:00

abstract：RATIONALE:The treatment of osteogenesis imperfecta (OI) requires a multidisciplinary approach to maximize function and reduce fracture incidence. The aim of this case report was to discuss an alternative surgical approach to stabilize a corrective osteotomy using the Fassier Duval (FD) system in an OI patient. PATIENT...

journal_title：Medicine

authors： Lin TY,Yang CY,Liu SC

更新日期：2017-11-01 00:00:00

abstract：:We aimed to investigate the relationship between total homocysteine (tHcy) levels in the plasma and renal function severity in patients with type 2 diabetes mellitus (T2DM) aged ≥75 years.We included 221 patients with T2DM aged ≥60 years (59 aged ≥75 years).tHcy levels among the 4 groups of patients aged ≥60 years sig...

journal_title：Medicine

authors： Ma N,Xu N,Yin D,Liu W,Wu M,Cheng X

更新日期：2020-07-02 00:00:00

abstract：:This study aims to evaluate the clinical and radiographic treatment outcomes of comminuted Mason type II radial head fractures, which underwent open reduction and internal fixation (ORIF) using a new implant (mother-child screw, MCS).This study included 16 patients (7 male and 9 female patients; mean age: 40.9 years, ...

journal_title：Medicine

authors： Shi Y,Wang GF,Mei K,Zhang J,Yun CJ,Qian C,Sun JY

更新日期：2018-03-01 00:00:00

abstract：:Although the outcome of renal transplantation in patients with systemic lupus erythematosus (SLE) has been studied, there are few reports about the outcome of patients with systemic sclerosis who have undergone renal transplantation. We retrospectively collected data from the United Network for Organ Sharing (UNOS) Sc...

journal_title：Medicine

authors： Chang YJ,Spiera H

更新日期：1999-11-01 00:00:00

abstract：RATIONALE:Multiple primary malignancies can occur in the same organ or in multiple organs or systems. Likewise, they can occur simultaneously or successively. Based on the timing of the diagnosis, they are classified as multiple synchronous (i.e., concurrent) or metachronous (i.e., successive) primary malignancies. The...

journal_title：Medicine

authors： Song L,Li Q,Yang K,Yin R,Wang D

更新日期：2018-06-01 00:00:00

abstract：:Nafamostat mesilate (NM), a synthetic serine protease inhibitor, has been used increasingly as an anticoagulant during continuous renal replacement therapy (CRRT). However, there, are limited data from randomized studies on NM use in patients with a bleeding tendency. This prospective study evaluated the efficacy and ...

journal_title：Medicine

authors： Choi JY,Kang YJ,Jang HM,Jung HY,Cho JH,Park SH,Kim YL,Kim CD

更新日期：2015-12-01 00:00:00

abstract：RATIONALE:Primary pulmonary diffuse large B-cell lymphoma (PPL-DLBCL) is rare and its clinical manifestations lack specificity. In this report, we present one case of PPL-DLBCL with complete clinical and imaging data, including uncontrast-enhanced CT, contrast-enhanced CT, and positron emission tomography (PET)/CT. Pre...

journal_title：Medicine

authors： Bai Y,Liang W

更新日期：2017-11-01 00:00:00