Visual function evaluation for low vision patients with advanced glaucoma.


:This study aimed to compare various visual function parameters for evaluating the quality of life (QOL) of patients with advanced glaucoma with low vision.In total, 44 eyes of advanced glaucoma patients with low vision were included in this cross-sectional study. A moving pattern edge band program was used to assess edge detection ability and the low vision quality-of-life (LVQOL) questionnaire was used for evaluating QOL scores of subjects. Correlation analyses between QOL scores and visual functional parameters including pattern edge band unit, visual acuity (VA), and Mean deviation (MD) of perimetry were performed. The areas under receiver operating characteristic curves (AUROCs) of diverse visual functional parameters were calculated.VA and pattern edge band unit were related to LVQOL score in all subjects. For patients with a decimal VA lower than 0.1, only the pattern edge band showed a significant correlation with the QOL associated with distant activities (P = .031). However, the MD of perimetry was not related to the QOL score. After sorting subjects into 2 groups according to the LVQOL score, VA and pattern edge band unit were significantly different (P < .01 and P = .029, respectively). The AUROC for edge detection ability using pattern edge band was higher than MD of perimetry.Assessment of edge detection ability using pattern edge band was meaningful for predicting QOL associated with visual performance in patients with far-advanced glaucoma. For these patients, edge detection could be used as an additional parameter for visual function with traditional VA and perimetry.


Medicine (Baltimore)




Jeon SJ,Jung Y,Jung CS,Park HL,Park CK




Has Abstract


2020-02-01 00:00:00
















  • Dopaminergic Therapy Modulates Cortical Perfusion in Parkinson Disease With and Without Dementia According to Arterial Spin Labeled Perfusion Magnetic Resonance Imaging.

    abstract::Arterial spin labeling (ASL) magnetic resonance imaging analyses allow for the quantification of altered cerebral blood flow, and provide a novel means of examining the impact of dopaminergic treatments. The authors examined the cerebral perfusion differences among 17 Parkinson disease (PD) patients, 17 PD with dement...


    pub_type: 杂志文章


    authors: Lin WC,Chen PC,Huang YC,Tsai NW,Chen HL,Wang HC,Lin TK,Chou KH,Chen MH,Chen YW,Lu CH

    更新日期:2016-02-01 00:00:00

  • Reconstruction of extensive plantar forefoot defects with free anterolateral thigh flap.

    abstract:PURPOSE:The aim of the soft tissue reconstruction of plantar forefoot should yield weight-bearing function and aesthetic contour, which poses a significant challenge for reconstructive surgeons to provide an appropriate flap according to the "like for like" reconstructive principle. Local flaps and pedicled flaps have ...


    pub_type: 杂志文章


    authors: Chen L,Zhang Z,Li R,Liu Z,Liu Y

    更新日期:2020-12-11 00:00:00

  • Analysis of mortality prognostic factors using model for end-stage liver disease with incorporation of serum-sodium classification for liver cirrhosis complications: A retrospective cohort study.

    abstract::Since the progression of cirrhosis is accelerated each time a complication recurs, the management and treatment of the complication is critical in enhancement of the quality of life and expectation of life in patients. The use of model for end-stage liver disease with incorporation of serum-sodium (MELD-Na) with physi...


    pub_type: 杂志文章


    authors: Kim Y,Kim K,Jang I

    更新日期:2019-11-01 00:00:00

  • Ki-67 labeling index is a predictive marker for a pathological complete response to neoadjuvant chemotherapy in breast cancer: A meta-analysis.

    abstract:BACKGROUND:A pathological complete response (pCR) after neoadjuvant chemotherapy (NCT) is a strong indicator of the benefit of therapy and presents an early surrogate for a favorable long-term outcome. It remains unclear whether Ki-67, a marker for tumor proliferation, can function as a predictor of the response to NCT...


    pub_type: 杂志文章,meta分析,评审


    authors: Tao M,Chen S,Zhang X,Zhou Q

    更新日期:2017-12-01 00:00:00

  • Confirmation of the pathogenicity of a mutation p.G337C in the COL1A2 gene associated with osteogenesis imperfecta.

    abstract::Mutation analysis as the gold standard is particularly important in diagnosis of osteogenesis imperfecta (OI) and it may be preventable upon early diagnosis. In this study, we aimed to analyze the clinical and genetic materials of an OI pedigree as well as to confirm the deleterious property of the mutation.A pedigree...


    pub_type: 杂志文章


    authors: Jia M,Shi R,Zhao X,Fu Z,Bai Z,Sun T,Zhao X,Wang W,Xu C,Yan F

    更新日期:2017-09-01 00:00:00

  • Rapid exacerbation of lymphocytic infundibuloneurohypophysitis.

    abstract:RATIONALE:Lymphocytic hypophysitis is a relatively rare autoimmune disease defined by lymphocytic infiltration to the pituitary. Its rarity and wide spectrum of clinical manifestations make clarification of the pathology difficult. Here, we describe a case we examined from the primary diagnosis to final discharge, show...


    pub_type: 杂志文章


    authors: Shibue K,Fujii T,Goto H,Yamashita Y,Sugimura Y,Tanji M,Yasoda A,Inagaki N

    更新日期:2017-03-01 00:00:00

  • Relationship between obesity and depression in Korean adults: Korea National Health and Nutrition Examination Survey 2014.

    abstract::Previous studies on the relationship between obesity and depression have produced conflicting results. And only a limited number of studies have been conducted in Asians, and few large-scale nationwide studies have been conducted in Korean populations.We investigated the relationship between obesity and depression in ...


    pub_type: 杂志文章


    authors: Hong SM,Hur YI

    更新日期:2017-12-01 00:00:00

  • Delayed intracranial subdural empyema following burr hole drainage: Case series and literature review.

    abstract:RATIONALE:A subdural empyema (SDE) following burr hole drainage of a chronic subdural hematoma (CSDH) can be difficult to distinguish from a recurrence of the CSDH, especially when imaging data is limited to a computed tomography (CT) scan. PATIENTS CONCERNS:All patients underwent burr hole drainage of the CSDH at fir...


    pub_type: 杂志文章


    authors: Kim YS,Joo SP,Song DJ,Kim SH,Kim TS

    更新日期:2018-05-01 00:00:00

  • Experiences and perceptions risk of health-care workers from coronavirus: A protocol for systematic review.

    abstract:BACKGROUND:Healthcare workers (HCWs) were at the frontline during the battle against coronavirus. Understanding and managing their fears and anxieties may hold lessons for handling future outbreaks. However, the experiences and perceptions risk of HCWs from coronavirus still remains to be controversial. Thus, the objec...


    pub_type: 杂志文章


    authors: Chen P,Lei J,Chen F,Zhou B

    更新日期:2020-05-01 00:00:00

  • Association between depression and enterovirus infection: A nationwide population-based cohort study.

    abstract::Enterovirus (EV) infection is common among children and adolescents. Few studies have investigated the relationship of depression after EV infection. This study explores an association between EV infection and subsequent depression in children and adolescents and assesses the risk of depression after EV infection with...


    pub_type: 杂志文章


    authors: Liao YT,Hsieh MH,Yang YH,Wang YC,Tsai CS,Chen VC,Gossop M

    更新日期:2017-02-01 00:00:00

  • Multiple Genetic Analysis System-Based Antibiotic Susceptibility Testing in Helicobacter pylori and High Eradication Rate With Phenotypic Resistance-Guided Quadruple Therapy.

    abstract::Antibiotics resistance in Helicobacter pylori (H. pylori) is the major factor for eradication failure. Molecular tests including fluorescence in situ hybridization, PCR-restriction fragment length polymorphism, and dual priming oligonucleotide-PCR (DPO-PCR) play critical roles in the detection of antibiotic susceptibi...


    pub_type: 杂志文章,随机对照试验


    authors: Dong F,Ji D,Huang R,Zhang F,Huang Y,Xiang P,Kong M,Nan L,Zeng X,Wu Y,Bao Z

    更新日期:2015-11-01 00:00:00

  • Clinical classification and individualized design for the treatment of basicranial artery injuries.

    abstract::This study aims to explore the principles of clinical classification and individualized treatment of basicranial artery injuries based on its anatomical correlation.The data of 172 patients with various types of basicranial artery injuries were retrospectively analyzed. Among these patients, 128 patients were male and...


    pub_type: 杂志文章


    authors: Yang H,Li SG,Xiang X,Lv Y,Chu LZ,Peng H,Wang F,Cao H,Liu J

    更新日期:2019-03-01 00:00:00

  • Acute effects of cinacalcet on arterial stiffness and ventricular function in hemodialysis patients: A randomized double-blinded crossover study.

    abstract:BACKGROUND:Serum calcium concentration (Ca) plays an essential role in a vascular muscle tone and myocardial contractility. Previously, we showed that acutely lowering Ca by hemodialysis reduced arterial stiffness. Cinacalcet is a calcimimetic that lowers Ca and parathyroid hormone (PTH). The aim of the present study w...


    pub_type: 杂志文章,随机对照试验


    authors: Poulin A,Bellemare PL,Fortier C,Mac-Way F,Desmeules S,Marquis K,Gaudreault V,Lebel M,Agharazii M

    更新日期:2017-05-01 00:00:00

  • Transabdominal preperitoneal laparoscopic approach for incarcerated inguinal hernia repair: A report of 73 cases.

    abstract::To investigate the efficacy, key technical points, and complication management of the transabdominal preperitoneal (TAPP) approach for incarcerated inguinal hernia repair. Seventy-three patients with incarcerated inguinal hernias underwent TAPP surgery in our department between Jan 2010 and Dec 2015. A retrospective r...


    pub_type: 杂志文章


    authors: Yang S,Zhang G,Jin C,Cao J,Zhu Y,Shen Y,Wang M

    更新日期:2016-12-01 00:00:00

  • Serum Phosphorylated Neurofilament-Heavy Chain, a Potential Biomarker, is Associated With Peripheral Neuropathy in Patients With Type 2 Diabetes.

    abstract::Neurofilament (NF), one of the major axonal cytoskeletal proteins, plays a critical role in degenerative diseases in both the central and the peripheral nervous systems. The aim of this study is to explore the relationship between serum phosphorylated neurofilament-heavy chain (pNF-H) and diabetic peripheral neuropath...


    pub_type: 杂志文章


    authors: Qiao X,Zhang S,Zhao W,Ye H,Yang Y,Zhang Z,Miao Q,Hu R,Li Y,Lu B

    更新日期:2015-11-01 00:00:00

  • Tamoxifen for amyotrophic lateral sclerosis: A randomized double-blind clinical trial.

    abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is the most common cause of motor neuron disease, and effective treatment for ALS is still lacking. Transactive response (TAR) -DNA-binding protein-43 (TDP-43) is aggregated in the neurons of ALS patients. Animal studies shown TDP-43 aggregation can be attenuated by enha...


    pub_type: 杂志文章,随机对照试验


    authors: Chen PC,Hsieh YC,Huang CC,Hu CJ

    更新日期:2020-05-29 00:00:00

  • Ideal cardiovascular health and incident hypertension: The longitudinal community-based Kailuan study.

    abstract::Ideal cardiovascular health (CVH) has been defined by the American Heart Association as the absence of disease and presence of 7 key health factors. Since it is unknown whether cumulative exposure to CVH reduces the risk of developing arterial hypertension, we prospectively examined the potential association between c...


    pub_type: 杂志文章


    authors: Zhao HY,Liu XX,Wang AX,Wu YT,Zheng XM,Zhao XH,Cui K,Ruan CY,Lu CZ,Jonas JB,Wu SL

    更新日期:2016-12-01 00:00:00

  • Pedunculated carcinoma ex pleomorphic adenoma of the nasal cavity: A unique case report.

    abstract:BACKGROUND:A carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy arising in or from a benign pleomorphic salivary adenoma. The parotid gland is the most common location of CXPAs. Minor salivary gland CXPAs of the nasal cavity are exceedingly rare, with only 6 documented in the literature. METHODS AND R...


    pub_type: 杂志文章


    authors: Liao PW,Chen YL,Chen JW

    更新日期:2016-09-01 00:00:00

  • Effect of phosphoric acid concentration used for etching on the microtensile bond strength to fluorotic teeth.

    abstract::To evaluate the effects of different etching concentrations of phosphoric acid on the microtensile bond strength of Adper Single Bond 2 to fluorotic teeth.Deidentified extracted teeth were collected, including 30 sound teeth, 30 teeth with mild fluorosis, 30 teeth with moderate fluorosis, and 30 teeth with severe fluo...


    pub_type: 杂志文章


    authors: Gu M,Lv L,He X,Li W,Guo L

    更新日期:2018-08-01 00:00:00

  • Do Recent Advances in Diagnostic and Therapeutic Procedures Negate the Benefit of Postmastectomy Radiotherapy in N1 Patients With a Low Risk of Locoregional Recurrence?

    abstract::Recent advances in breast cancer management might make the use of postmastectomy radiotherapy (PMRT) redundant in the treatment of pT1/T2N1 patients. We investigated the impact of PMRT on disease-free survival (DFS) in these patients who have a low risk of locoregional recurrence (LRR) after contemporary multidiscipli...


    pub_type: 杂志文章


    authors: Chang JS,Lee J,Kim KH,Sohn JH,Kim SI,Park BW,Chung HC,Keum KC,Suh CO,Kim YB

    更新日期:2015-08-01 00:00:00

  • Elevated Th22 cells and related cytokines in patients with epithelial ovarian cancer.

    abstract::This study is conducted to investigate the involvement of T-helper (Th) cells and regulatory T cells in epithelial ovarian cancer (EOC).The percentages of Th22, Th17, Th1, and regulatory T cells in the peripheral blood of EOC patients, benign ovarian epithelial neoplasm (BOEN) patients, and healthy control (HC) were e...


    pub_type: 杂志文章


    authors: Wang T,Zhang Z,Xing H,Wang L,Zhang G,Yu N,Wang J,Guo W,Jiang J

    更新日期:2017-10-01 00:00:00

  • Enterococcal bacteremia: clinical features, the risk of endocarditis, and management.

    abstract::The enterococci, members of the group D streptococci and the predominant aerobic streptococci of the gastrointestinal and female genital tracts, have long been recognized as significant pathogens in infective endocarditis. Over the past 2 decades, enterococci have become increasingly important nosocomial pathogens, re...


    pub_type: 杂志文章,评审


    authors: Maki DG,Agger WA

    更新日期:1988-07-01 00:00:00

  • Spinal dysraphism and dislocated hip: Beware of anomalous sciatic nerve through Ilium, a case report.

    abstract:RATIONALE:The sciatic nerve runs a predictable course combining L4-S3 nerve roots through the true pelvis and under the greater sciatic notch. There are reports of bony protuberances from the sacrum and ilium in cases of spinal dysraphism; however advanced imaging, treatment, or outcomes are not described. There are no...


    pub_type: 杂志文章


    authors: Whitaker AT,Kasser J,Kim YJ

    更新日期:2018-03-01 00:00:00

  • Risk factors related to acupuncture response in postmenopausal women with stress urinary incontinence: Secondary analysis of a randomized controlled trial.

    abstract::Postmenopausal women are at a higher risk of stress urinary incontinence (SUI). In a previous trial, electroacupuncture (EA) was shown to be an effective treatment for women with SUI. Here we present a secondary analysis to investigate the specific factors associated with response to acupuncture therapy among postmeno...


    pub_type: 杂志文章,随机对照试验


    authors: Jiao R,Liu Y,Liu B,Liu Z

    更新日期:2019-04-01 00:00:00

  • Computed tomography-guided cryoablation for adrenal metastases: local control and survival.

    abstract::To evaluate the feasibility, local control, and survival after computed tomography (CT)-guided cryoablation for adrenal metastases.This study included 31 consecutive patients with adrenal metastases who were treated by CT-guided cryoablation in our center from July 2011 to October 2017. The technical success rate, loc...


    pub_type: 杂志文章


    authors: Zhang W,Sun LJ,Xu J,Fu YF,Zhuang ZX

    更新日期:2018-12-01 00:00:00

  • Efficacy and safety of traditional Chinese medicine for erosive oral lichen planus: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:Oral lichen planus (OLP) is a common disease among oral mucous membrane diseases. Erosive oral lichen planus (EOLP) is a type of OLP, it has a potential tendency of cancerization. There have been some randomized controlled trials (RCTs) using Traditional Chinese Medicine (TCM) to treat EOLP. No systematic re...


    pub_type: 杂志文章,meta分析


    authors: You Y,Huang X,Chen Y,You Y

    更新日期:2020-11-25 00:00:00

  • A High Circulating Tumor Cell Count in Portal Vein Predicts Liver Metastasis From Periampullary or Pancreatic Cancer: A High Portal Venous CTC Count Predicts Liver Metastases.

    abstract::Circulating tumor cells (CTCs) released from a periampullary or pancreatic cancer can be more frequently detected in the portal than the systemic circulation and potentially can be used to identify patients with liver micrometastases. Aims of this study is to determine if CTCs count in portal venous blood of patients ...


    pub_type: 杂志文章


    authors: Tien YW,Kuo HC,Ho BI,Chang MC,Chang YT,Cheng MF,Chen HL,Liang TY,Wang CF,Huang CY,Shew JY,Chang YC,Lee EY,Lee WH

    更新日期:2016-04-01 00:00:00

  • Disabling tremor induced by long-term use of sodium valproate and lamotrigine: Case report.

    abstract:RATIONALE:Sodium valproate (VPA) and lamotrigine (LTG) are widely used antiepileptic drugs, disabling postural, and action tremors after using LTG with VPA were reported in 1993. However, in this study, we describe a patient in whom disabling resting-type tremor induced by 2-year use of VPA and LTG. PATIENT CONCERNS:A...


    pub_type: 杂志文章


    authors: He ZF,Chen J,Zhou CN,Rao Z,Wang XH

    更新日期:2017-11-01 00:00:00

  • Fatal and extensive multiorgan hemorrhages in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis: An autopsy case report.

    abstract:INTRODUCTION:Anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5 Ab) is an autoantigen associated with dermatomyositis (DM). Anti-MDA5 Ab-positive DM patients frequently exhibit clinically amyopathic dermatomyositis (CADM), and develop rapidly progressive interstitial lung disease (RPILD). Even with ear...


    pub_type: 杂志文章


    authors: Watanabe T,Takizawa N,Nagasaka T,Nakamura Y,Ikai H,Yamamoto M,Murai Y,Takasugi K,Yokoyama-Kokuryo W,Fujita Y

    更新日期:2020-01-01 00:00:00

  • The association between statin use and survival of esophageal cancer patients: A systematic review and meta-analysis.

    abstract::Whether statin use has any impact on survival of esophageal cancer patients remains controversial. Therefore, we conducted a meta-analysis focusing on current topic for the first time.We systematically searched the following databases for relevant studies comparing survival between statin users and non-users among eso...


    pub_type: 杂志文章,meta分析


    authors: Deng HY,Lan X,Zheng X,Zha P,Zhou J,Wang RL,Jiang R,Qiu XM

    更新日期:2019-07-01 00:00:00