Two-stage hepatectomy for multiple giant alveolar echinococcosis.

Abstract:

:Alveolar echinococcosis is a chronically progressive and potentially fatal disease. Patients with multiple giant alveolar echinococcosis have a poor prognosis when radical resection cannot be achieved, but curative resection can be limited by low future remnant liver volumes. In these cases, 2-stage liver resection may be a better choice: after a first-stage hepatectomy with partial resection, liver regeneration is allowed in the residual liver before proceeding to the second-stage hepatectomy. In this study, we therefore retrospectively reviewed and evaluated the safety and feasibility of two-stage hepatectomy in patients with multiple giant alveolar echinococcosis.We reviewed the data for all patients who underwent 2-stage hepatectomy for multiple giant alveolar echinococcosis between August 2013 and December 2015 at either the West China Hospital of Sichuan University or the Hospital of Ganzi Tibetan Autonomous Prefecture.We identified 7 patients in whom 2-stage hepatectomy was completed. During the first-stage hepatectomy, 4 patients underwent right-sided hepatectomy and the other 3 underwent left-sided hepatectomy. The second-stage hepatectomies were successfully performed 3 months after the first-stage procedures. All patients had follow-up durations of >1 year; there were no cases of operation-related mortality, and no patients experienced disease recurrence.Two-stage hepatectomy is safe and feasible for patients with multiple giant alveolar echinococcosis.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Shen HD,Chen KF,Li B,Zhang HZ,Yang KM,Chen Y,Li JX,Chen ZY,Meng T,Ma Z,Li HZ

doi

10.1097/MD.0000000000007819

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

e7819

issue

33

eissn

0025-7974

issn

1536-5964

pii

00005792-201708180-00047

journal_volume

96

pub_type

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