Roentgenographic Evaluation of the Spine in Patients With Osteogenesis Imperfecta.

Abstract:

:Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder that leads to bone weakness and deformities, especially in the spine, which can lead to poor outcomes.The aim of this study was to find patterns and risk factors in spinal deformities in patients with OI.In a retrospective study, 70 patients with OI were selected. Radiographs of the spine were evaluated. We observed the presence or absence of the following changes: biconcave vertebrae, chest and vertebral deformities, unilateral rib, and thoracolumbar kyphosis. The greater curve was considered the primary one, and the secondary curve considered compensatory.In the study sample, we observed that the patients' ages ranged between 7 and 50 years, with a mean equal to 13 years, and 76% had scoliosis. In 68% of cases the main curve in the thoracic region was observed with the convexity to the right.The following was found in patients with OI: scoliosis, biconcave vertebrae, vertebral and chest deformity, unilateral rib, and thoracolumbar kyphosis. The thoracolumbar kyphosis is highly associated with thoracic hypokyphosis in patients with OI.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

de Lima MV,de Lima FV,Akkari M,Resende VR,Santili C

doi

10.1097/MD.0000000000001841

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

e1841

issue

47

eissn

0025-7974

issn

1536-5964

pii

00005792-201511240-00004

journal_volume

94

pub_type

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