Gemstone spectral imaging in lung cancer: A preliminary study.

Abstract:

:The present study aimed to evaluate the application of gemstone spectral imaging (GSI) for multi-parameter quantitative measurement in lung cancer.The study retrospectively enrolled 30 patients with lung cancer who underwent chest contrast enhanced CT scan with GSI mode. The GSI viewer was used for image display and data analysis. Optimal energy value, CT values at 40 keV, 70 keV and optimal energy level, spectral curve slope, effective atomic number (Zeff), iodine concentration (IC), and water concentration (WC) at the region of interest were measured and analyzed by statistical methods.The optimal energy value for optimal contrast-to-noise ratio on plain scan, arterial phase and venous phase was 62.2 ± 5.38 keV, 50.63 ± 3.84 keV, and 52.5 ± 3.7 keV, respectively. There were significant differences in CT values at different energy levels on each scan phase (P = .033). The spectral curve slope values among 40 to 70 keV, 40 to 100 keV, and 40 to 140 keV were significantly different (P < .001). No significant difference with the slope between arterial phase and venous phase at each energy level interval was observed. Zeff on plain scan, arterial phase, and venous phase was 7.75 ± 0.15, 8.38 ± 0.37, and 8.38 ± 0.30, respectively. Positive correlation was observed among IC, normalized IC, and Zeff on enhanced scan.Multiparameter of GSI can be used for lung tumor lesion evaluation. Different parameters were correlated and provide multiple qualitative and quantitative information together.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Jia Y,Xiao X,Sun Q,Jiang H

doi

10.1097/MD.0000000000011170

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

e11170

issue

29

eissn

0025-7974

issn

1536-5964

pii

00005792-201807200-00007

journal_volume

97

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Risk of Retinal Vein Occlusion Following End-Stage Renal Disease.

    abstract::The aim of the study was to investigate the risk of retinal vein occlusion (RVO) following end-stage renal disease (ESRD). The study was designed as a retrospective, nationwide, matched cohort study. The subjects were ESRD patients identified by the International Classification of Diseases, Ninth Revision, Clinical Mo...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000003474

    authors: Chang YS,Weng SF,Chang C,Wang JJ,Tseng SH,Wang JY,Jan RL

    更新日期:2016-04-01 00:00:00

  • Congenital scoliosis in Smith-Magenis syndrome: a case report and review of the literature.

    abstract::The Smith-Magenis syndrome (SMS) is a complex and rare congenital condition that is characterized by minor craniofacial anomalies, short stature, sleep disturbances, behavioral, and neurocognitive abnormalities, as well as variable multisystemic manifestations. Little is reported about spinal deformity associated with...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000000705

    authors: Li Z,Shen J,Liang J,Sheng L

    更新日期:2015-05-01 00:00:00

  • Effects of hyperbaric oxygen therapy on the expression levels of the inflammatory factors interleukin-12p40, macrophage inflammatory protein-1β, platelet-derived growth factor-BB, and interleukin-1 receptor antagonist in keloids.

    abstract:BACKGROUND:Our study aimed to screen and explore the expression of inflammatory factors in keloid patients and to investigate how hyperbaric oxygen (HBO) therapy affects the expression levels of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP-1β), platelet-derived growth factor-BB (PDGF-BB), and i...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/MD.0000000000019857

    authors: Hao Y,Dong X,Zhang M,Liu H,Zhu L,Wang Y

    更新日期:2020-04-01 00:00:00

  • Tamoxifen for amyotrophic lateral sclerosis: A randomized double-blind clinical trial.

    abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is the most common cause of motor neuron disease, and effective treatment for ALS is still lacking. Transactive response (TAR) -DNA-binding protein-43 (TDP-43) is aggregated in the neurons of ALS patients. Animal studies shown TDP-43 aggregation can be attenuated by enha...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000020423

    authors: Chen PC,Hsieh YC,Huang CC,Hu CJ

    更新日期:2020-05-29 00:00:00

  • Creatine kinase in the U.S. population: Impact of demographics, comorbidities, and body composition on the normal range.

    abstract:BACKGROUND:Creatine kinase (CK) values are a critical part of the workup of suspected myopathies and are often assessed in patients that develop myalgia on statin therapy. CK elevations may influence the initiation and cessation of statin treatment, and incidentally discovered CK elevation may lead to further testing. ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004344

    authors: George MD,McGill NK,Baker JF

    更新日期:2016-08-01 00:00:00

  • TNM Staging of Colorectal Cancer Should be Reconsidered According to Weighting of the T Stage: Verification Based on a 25-Year Follow-Up.

    abstract::The gradient monotonicity of existing tumor, node, metastases staging systems for colorectal cancer is unsatisfactory. Our proposed T-plus staging system strengthens weighting of the T stage. In this study, applicability of the T-plus staging system was verified with data of a Chinese colorectal cancer center.Records ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002711

    authors: Li J,Yi CH,Hu YT,Li JS,Yuan Y,Zhang SZ,Zheng S,Ding KF

    更新日期:2016-02-01 00:00:00

  • Acute Splenic Infarction at an Academic General Hospital Over 10 Years: Presentation, Etiology, and Outcome.

    abstract::Few case series provide a current, comprehensive, and detailed description of splenic infarction (SI), an uncommon condition.Retrospective chart review complemented by imaging evaluation and patient follow-up.All adult patients with a confirmed diagnosis of acute SI discharged over 10 years from a single academic cent...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001363

    authors: Schattner A,Adi M,Kitroser E,Klepfish A

    更新日期:2015-09-01 00:00:00

  • Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome in Adults: Prognostic Factors for Outcomes.

    abstract::Despite a therapeutic option for severe acute respiratory distress syndrome (ARDS), the survival benefit of venovenous extracorporeal membrane oxygenation (VV-ECMO) is still controversial in adults. This study was aimed at investigating the prognostic factors for ECMO-treated ARDS in adult patients.From 2012 to 2015, ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002870

    authors: Wu MY,Huang CC,Wu TI,Wang CL,Lin PJ

    更新日期:2016-02-01 00:00:00

  • Increased IgM-containing circulating immune complexes in patients co-infected with hepatitis C and hepatitis B.

    abstract::To assess the role of circulating immune complexes (CIC) in chronic hepatitis C virus (HCV) infection, the relative frequency of CIC was determined in 60 patients with chronic hepatitis C alone, 19 patients co-infected with hepatitis B and C, 15 asymptomatic HCV carriers, and 54 healthy controls. Levels of CIC were de...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-199505000-00003

    authors: Tsai JF,Jeng JE,Chang WY,Ho MS,Lin ZY,Tsai JH

    更新日期:1995-05-01 00:00:00

  • Rotational atherectomy ablation for an unexpandable stent under the guide of IVUS: A case report.

    abstract:RATIONALE:Inadequate stent expansion due to rigid calcified may result in restenosis lesions, but the available options are limited. PATIENT CONCERNS:We report a case via the trans-radial approach of the severely underexpanded freshly deployed stent due to heavily calcified plaques DIAGNOSES:: Coronary angiography rev...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009978

    authors: Si D,Liu G,Tong Y,He Y

    更新日期:2018-02-01 00:00:00

  • Poorer prognosis in patients with advanced gastric squamous cell carcinoma compared with adenocarcinoma of the stomach: Case report.

    abstract:RATIONALE:Primary squamous cell carcinoma (SCC) of the stomach is a rare disease. The pathogenesis and prognosis of advanced SCC remains to be elucidated. The aim of the current study was to investigate the prognosis of recurrent or metastatic SCC of the stomach. PATIENT CONCERNS:A retrospective study examined the cli...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009224

    authors: Meng Y,Zhang J,Wang H,Zhang Y,Sun R,Zhang Z,Gao F,Huang C,Zhang S

    更新日期:2017-12-01 00:00:00

  • Status and associated characteristics of HIV disclosure among people living with HIV/AIDS in Liangshan, China: A cross-sectional study.

    abstract::Human immunodeficiency virus (HIV) disclosure is a prerequisite to get access to antiretroviral therapy (ART) and social support. Increased disclosure of HIV status has been shown to reduce mother-to-child transmission and high-risk sexual behaviors. Limited studies were conducted to get an insight into HIV disclosure...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016681

    authors: Yin Y,Yang H,Xie X,Wang H,Nie A,Chen H

    更新日期:2019-08-01 00:00:00

  • Pathologic femoral fracture due to tenofovir-induced Fanconi syndrome in patient with chronic hepatitis B: A case report.

    abstract:RATIONALE:We report a case of a hepatitis B virus (HBV)-positive patient with preexisting bone disease who developed tenofovir-induced Fanconi syndrome and subsequently sustained pathologic fracture. To our best knowledge, this is the first report in the English literature about pathologic femoral fracture due to tenof...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008760

    authors: Suh YS,Chun DI,Choi SW,Lee HW,Nho JH,Kwon SH,Cho JH,Won SH

    更新日期:2017-11-01 00:00:00

  • Cisplatin-induced cardiotoxicity with midrange ejection fraction: A case report and review of the literature.

    abstract:RATIONALE:Cisplatin monotherapy-induced cardiotoxicity is rare, and the prevalence remains unknown. It's extremely important to stop cisplatin when cardiotoxicity is considered. PATIENT CONCERNS:A 53-year-old woman developed cervical cancer. She was administered cisplatin (37 mg/m/wk) for 3 weeks, but the left ventric...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000013807

    authors: Hu Y,Sun B,Zhao B,Mei D,Gu Q,Tian Z

    更新日期:2018-12-01 00:00:00

  • Do genetic polymorphisms modulate response rate and toxicity of Cisplatin associated with radiotherapy in laryngeal squamous cell carcinoma?: a case report.

    abstract:UNLABELLED:Cisplatin (CDDP) plus radiotherapy (RT) has been used to treat advanced laryngeal squamous cell carcinoma (LSCC) patients. Single nucleotide polymorphisms (SNPs) may be responsible for differences in chemo/radiosensitivity and side effects in those patients. We reported an advanced LSCC patient, who obtained...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000578

    authors: Lopes-Aguiar L,Visacri MB,Nourani CML,Costa EFD,Nogueira GAS,Lima TRP,Pincinato EC,Moriel P,Altemani JMC,Lima CSP

    更新日期:2015-04-01 00:00:00

  • Interpretation and Prognostic Value of Positron Emission Tomography-Computed Tomography After Induction Chemotherapy With or Without Radiation in IIIA-N2 Non-small Cell Lung Cancer Patients Who Receive Curative Surgery.

    abstract::We evaluate the correlation of clinical staging on positron emission tomography-computed tomography (PET-CT) and pathologic staging and the prognostic value of PET-CT after induction chemotherapy in patients with locally advanced nonsmall cell lung cancer (NSCLC). We analyzed 42 cases of clinical stage IIIA-N2 NSCLC w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000955

    authors: Kim SH,Lee JH,Lee GJ,Jeong S,Kwak YK,Kim HK,Cho DG,Park YH,Yu M,Yoon SC

    更新日期:2015-06-01 00:00:00

  • MECP2 expression in gastric cancer and its correlation with clinical pathological parameters.

    abstract::This study is to investigate the expression of methyl CpG binding protein 2 (MECP2) in gastric cancer (GC) and its clinical significance.Expression of MECP2 was analyzed in 69 cases of GC tissues and 12 paracancerous tissues, either by qRT-PCR at the mRNA level or by Western blot and immunochemistry at the protein lev...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007691

    authors: Zhang J,Zhao J,Gao N,Wang Y,Chen Y,Han J

    更新日期:2017-08-01 00:00:00

  • Antiglomerular basement membrane antibody-mediated glomerulonephritis and Goodpasture's syndrome.

    abstract::The originally dismal prognosis associated with anti-GBM Ab-mediated GN and Goodpasture's syndrome may be changing as we recognize a broader spectrum of disease, improve general supportive care, and improve specific treatment. Immunosuppressive therapy, if started early in the course of disease, may prevent or allow r...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/00005792-197909000-00002

    authors: Briggs WA,Johnson JP,Teichman S,Yeager HC,Wilson CB

    更新日期:1979-09-01 00:00:00

  • Hyperthyroidism-associated hypercalcemic crisis: A case report and review of the literature.

    abstract:RATIONALE:Hyperthyroidism is one of the major clinical causes of hypercalcaemia, however, hyperthyroidism-related hypercalcemic crisis is rare, only 1 case have been reported. The potential mechanisms are still not too clear. It may be related that thyroid hormone stimulate bone turnover, elevate serum calcium, increas...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000006017

    authors: Chen K,Xie Y,Zhao L,Mo Z

    更新日期:2017-01-01 00:00:00

  • Impacts of 12-dose regimen for latent tuberculosis infection: Treatment completion rate and cost-effectiveness in Taiwan.

    abstract::Treatment of latent tuberculosis infection (LTBI) is essential for eradicating tuberculosis (TB). Moreover, the patient adherence is crucial in determining the effectiveness of TB control. Isoniazid given by DOTS daily for 9 months (9H) is the standard treatment for LTBI in Taiwan. However, the completion rate is low ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004126

    authors: Huang YW,Yang SF,Yeh YP,Tsao TC,Tsao SM

    更新日期:2016-08-01 00:00:00

  • Repair of a defect in the cervical trachea with thyroid-pericardium flap: A case report.

    abstract:RATIONALE:Primary end-to-end anastomosis is common in adult trachea resection. Nevertheless, considering that the utilization of grafts is still essential for restoring defect in long-segment tracheal resection surgery, long-segment tracheal resection and reconstruction still remain challenging. Herein we present a nov...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017871

    authors: Xie H,Zhang Y,Yu F,Wang X

    更新日期:2019-11-01 00:00:00

  • Misinterpretation of carbon dioxide monitoring because of deadspace of heat and moisture exchanger with a filter in pediatric anesthesia: A case report.

    abstract:RATIONALE:When patients are intubated and treated with mechanical ventilation, the upper respiratory tract is bypassed by the flow of dry and cold air. To prevent disturbances of airway homeostasis, a heat and moisture exchanger filter (HMEF) has been applied to breathing circuit. PATIENT CONCERNS:A 4-month-old male i...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012158

    authors: Lee JE,Kim JH,Kim SO

    更新日期:2018-08-01 00:00:00

  • X-linked hypophosphatemia: a clinical, biochemical, and histopathologic assessment of morbidity in adults.

    abstract::Research and management of XLH have concentrated on the disease in childhood, and the natural history and morbidity of XLH in adult life are thus poorly understood. We have studied 22 adults (6 men) with XLH to clarify these aspects of this most common inherited form of rickets and osteomalacia. Most study participant...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:

    authors: Reid IR,Hardy DC,Murphy WA,Teitelbaum SL,Bergfeld MA,Whyte MP

    更新日期:1989-11-01 00:00:00

  • Clinical efficacy of xenon versus propofol: A systematic review and meta-analysis.

    abstract:BACKGROUND:Interest in the anesthetic use of xenon, a noble gas, has waxed and waned for decades, and the clinical effects of xenon are still debated. We performed a meta-analysis to compare the clinical efficacy of xenon with that of propofol. METHODS:Electronic searches were performed through December 2017 using var...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000010758

    authors: Xia Y,Fang H,Xu J,Jia C,Tao G,Yu B

    更新日期:2018-05-01 00:00:00

  • Use of statins and the risk of delirium in critically ill and surgical patients: Protocol of a systematic review and meta-analysis.

    abstract:BACKGROUND:The critically ill and surgical patients are at significant risk of delirium, which is associated with a high morbidity and mortality. The association between statin use and the incidence of delirium is still controversial. In this article, we will perform a systematic review and meta-analysis of published s...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000013679

    authors: Zeng H,Li Z,He G,Han Y,Fu W,Wen J

    更新日期:2018-12-01 00:00:00

  • Comparison of radiological outcomes and complications between single-level and multilevel anterior cervical discectomy and fusion (ACDF) by using a polyetheretherketone (PEEK) cage-plate fusion system.

    abstract::This study aimed to compare the differences in radiological outcomes and complications between single- and multilevel anterior cervical discectomy and fusion (ACDF) by using a polyetheretherketone (PEEK) cage-plate fusion system.Fifty-seven patients who underwent ACDF via the PEEK cage-plate fusion system were enrolle...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014277

    authors: Lee HC,Chen CH,Wu CY,Guo JH,Chen YS

    更新日期:2019-02-01 00:00:00

  • Chronic eosinophilic pneumonia. A report of 19 cases and a review of the literature.

    abstract::Clinical, roentgenographic and pathologic findings in patients with chronic eosinophilic pneumonia, including 19 additional cases, have been reviewed and summarized. Most patients present with subacute respiratory and constitutional symptoms and have failed to respond to therapy for presumptive pneumonia. A previous h...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00005792-198805000-00002

    authors: Jederlinic PJ,Sicilian L,Gaensler EA

    更新日期:1988-05-01 00:00:00

  • Brief topical sodium nitrite and its impact on the quality of life in patients with sickle leg ulcers.

    abstract::Cutaneous ulceration from sickle cell disease negatively impacts quality of life. Topical sodium nitrite has previously been shown to reduce the size of sickle leg ulcers. This study examined how topical sodium nitrite impacted the quality of life scores in patients with sickle leg ulcers.We prospectively collected da...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/MD.0000000000012614

    authors: Connor JL Jr,Sclafani JA,Kato GJ,Hsieh MM,Minniti CP

    更新日期:2018-11-01 00:00:00

  • The effect of Baduanjin exercise on the quality of life in patients recovering from COVID-19: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Since the outbreak of COVID-19, the number of COVID-19 patients has been on the rise. With the improvement of diagnosis and treatment level in various countries, more and more patients have recovered. Baduanjin exercise is a traditional Chinese health care method with a long history, easy-to-learn, and remar...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022229

    authors: Ma Q,Yang Z,Zhu F,Chen H,Yang H,Wang S

    更新日期:2020-09-11 00:00:00

  • Delayed degeneration of the left fornical crus with verbal memory impairment in a patient with mild traumatic brain injury: A case report.

    abstract:RATIONALE:We report on a patient who showed delayed degeneration of the left fornical crus with verbal memory impairment following mild traumatic brain injury (TBI), which was demonstrated by diffusion tensor tractography (DTT). PATIENT CONCERNS:: fter flexion and hyperextension of her head to the opposite side, the pa...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009219

    authors: Jang SH,Seo JP

    更新日期:2017-12-01 00:00:00