TNM Staging of Colorectal Cancer Should be Reconsidered According to Weighting of the T Stage: Verification Based on a 25-Year Follow-Up.

Abstract:

:The gradient monotonicity of existing tumor, node, metastases staging systems for colorectal cancer is unsatisfactory. Our proposed T-plus staging system strengthens weighting of the T stage. In this study, applicability of the T-plus staging system was verified with data of a Chinese colorectal cancer center.Records of 2080 nonmetastatic, advanced cancer patients undergoing colorectal cancer surgery from 1985 to 2011 were reviewed for T, N stage pathology and follow-up information. Using overall and disease-specific survival data, the 7th edition tumor, node, metastases staging system and the T-plus staging system were compared for stage homogeneity and discrimination and gradient monotonicity.For gradient monotonicity, the T-plus staging system was superior for both colon and rectal cancer. With Kaplan-Meier survival curves, the T-plus staging system discriminated among different stages, and the corresponding survival was inversely associated with the stage. However, for the 7th edition tumor, node, metastases staging system, stage IIIa had a better prognosis than stage II for rectal cancer and stage I for colon cancer. For homogeneity within the same stage and discrimination between different stages, the 2 staging systems were similar for colorectal cancer, but the T-plus system was clearly better for colon cancer.The T-plus staging system provides good gradient monotonicity. For future colorectal cancer staging systems, we propose replacement of lymph node status as the criterion to discriminate colorectal cancer stage II and stage III with greater weighting of the T stage.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Li J,Yi CH,Hu YT,Li JS,Yuan Y,Zhang SZ,Zheng S,Ding KF

doi

10.1097/MD.0000000000002711

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

e2711

issue

6

eissn

0025-7974

issn

1536-5964

pii

00005792-201602090-00052

journal_volume

95

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Ultrasound-guided high-intensity focused ultrasound in the treatment of uterine fibroids.

    abstract::The aim of the present study was to investigate factors affecting ablation effect and safety of ultrasound-guided high-intensity focused ultrasound (USgHIFU) for uterine fibroids (UFs).A retrospective analysis of 346 patients with symptomatic UFs who were treated with USgHIFU was performed. All UFs was grouped based o...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014566

    authors: Fan HJ,Zhang C,Lei HT,Cun JP,Zhao W,Huang JQ,Zhai Y

    更新日期:2019-03-01 00:00:00

  • Selective dorsal neurotomy in the treatment of premature ejaculation: A protocol for systematic review and meta-analysis.

    abstract:INTRODUCTION:Premature ejaculation (PE) affects 8% to 30% of adult men worldwide. Recently, the incidence of PE is on the rise. A series of prior studies suggested that the incidence of PE is related to various biological factors as low testosterone, low serum vitamin D, diabetes, lower urinary tract symptoms, and othe...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000021866

    authors: Li G,Chang D,Chen D,Zhang P,You Y,Huang X,Cai J

    更新日期:2020-08-21 00:00:00

  • Spontaneous remission of West syndrome following a human herpesvirus 7 infection in a Chinese infant: A case report.

    abstract:RATIONALE:West syndrome (WS) is an age-dependent epileptic encephalopathy that is characterized by intractable epileptic seizures, hypsarrhythmia, and observed through electroencephalogram (EEG) and significant neurodevelopmental regression. The spontaneous remission of epileptic seizure is clinically rare and has not ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016441

    authors: Li H,Wang B,Shan L,Du L,Jia F

    更新日期:2019-07-01 00:00:00

  • Cardiac tamponade complicating thoracentesis in a patient after left pneumonectomy: A case report.

    abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019778

    authors: Zheng M,Kang Y,Wang T,Wei J

    更新日期:2020-04-01 00:00:00

  • Direct reconstruction of chronic extensor digitorum longus tendon rupture using interposed scar tissue in the foot: A case report.

    abstract:RATIONALE:Primary repair of acute ligament injury is possible due to the proximity of the ends. In the case of chronic injury, however, primary repair is difficult because the ends of ruptured ligament will have receded, and tendon graft, transfer, or reconstruction is needed. Satisfactory clinical results have been re...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022506

    authors: Yeo ED,Han JK,Lee HS,Won SH,Jung KJ,Chang HJ,Cha JS,Ahn H,Lee DW,Kang JK,Kim WJ

    更新日期:2020-10-02 00:00:00

  • Orthostatic Hypotension and Mortality in Elderly Frail Patients: A Retrospective Cross-Sectional Study.

    abstract::Orthostatic hypotension (OH) is a common problem in the elderly age group, and some studies have reported an association between OH and increased mortality. We evaluated possible associations between OH and mortality in a retrospective study of frail elderly patients who came for a comprehensive geriatric assessment. ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000977

    authors: Freud T,Punchik B,Press Y

    更新日期:2015-06-01 00:00:00

  • Subaortic stenosis revisited: the importance of the dynamic pressure gradient.

    abstract::Brachfeld and Gorlin's revised concept of subaortic stenosis derived from their recognition that the large magnitudes of the pressure gradients were incompatible with the relatively mild anatomic lesions found at surgery in 3 of their patients, and the rapidity of their arterial pulse upstroke. They proposed that a gr...

    journal_title:Medicine

    pub_type: 传,评论,历史文章,杂志文章

    doi:

    authors: Criley JM,Siegel RJ

    更新日期:1993-11-01 00:00:00

  • Primary pulmonary myoepithelial carcinoma in a young woman: A case report and review of literature.

    abstract:RATIONALE:Myoepithelial carcinoma mainly occurs in the salivary glands, but myoepithelial carcinoma of the lung is extremely rare neoplasm whose biological behavior and clinical course still remain to be fully elucidated. Although considered as low-grade carcinoma, these tumors have a high rate of recurrence or distant...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000010049

    authors: Zhou X,Yu M,Zhuo H,Zhang S

    更新日期:2018-03-01 00:00:00

  • The Relationship Between Educational Years and Phonemic Verbal Fluency (PVF) and Semantic Verbal Fluency (SVF) Tasks in Spanish Patients Diagnosed With Schizophrenia, Bipolar Disorder, and Psychotic Bipolar Disorder.

    abstract::Semantic and verbal fluency tasks are widely used as a measure of frontal capacities. It has been well described in literature that patients affected by schizophrenic and bipolar disorders present a worse execution in these tasks. Some authors have also noted the importance of educational years. Our objective is to an...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001596

    authors: García-Laredo E,Maestú F,Castellanos MÁ,Molina JD,Peréz-Moreno E

    更新日期:2015-09-01 00:00:00

  • A medium-term follow-up of adult lumbar tuberculosis treating with 3 surgical approaches.

    abstract::Surgical intervention is an important option for treating lumbar tuberculosis. Previous studies have reported different surgical intervention procedures. To our knowledge, few studies have compared the clinical results of mid-term follow-up of 3 different surgeries in surgical treatment of spinal tuberculosis. This st...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008574

    authors: Zhang H,Guo Q,Guo C,Wu J,Liu J,Gao Q,Wang Y

    更新日期:2017-11-01 00:00:00

  • Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms.

    abstract::Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007832

    authors: Qin F,Li Z,Fang X,Zhao X,Liu J,Wu D,Lai N

    更新日期:2017-08-01 00:00:00

  • Association of high waist-to-height ratio with functional outcomes in patients with acute ischemic stroke: A report from the ACROSS-China study.

    abstract::The aim of our study was to investigate the relationship between the waist-to-height ratio (WHR) and all-cause mortality and functional outcomes after acute ischemic stroke in a prospective cohort study.A total of 2076 patients (36.66% females) with ischemic stroke were analyzed from ACROSS-China, which is a nationwid...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000006520

    authors: Yu P,Pan Y,Zheng H,Wang X,Yan H,Tong X,Jing J,Zhang X,Guo L,Wang Y,investigators for the Survey on Abnormal Glucose Regulation in Patients With Acute Stroke Across China (ACROSS-China).

    更新日期:2017-03-01 00:00:00

  • Role of the physical fitness test in risk prediction of diabetes among municipal in-service personnel in Guangxi.

    abstract::To explore the relationship between risk prediction of diabetes mellitus (DM) and different physical fitness parameters in municipal in-service personnel in Guangxi.This was a cross-sectional study conducted in China from July 2015 to December 2016. We enrolled in-service adults (20-65 year of age) from public institu...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015842

    authors: Zhao M,Wu Z,Huang Y,Jiang Z,Mo X,Lowis H,Zhao Y,Zhang M

    更新日期:2019-05-01 00:00:00

  • Non-pharmacological interventions for patients with dementia: A protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:This protocol for a systematic review describes the methods that will be used to evaluate the efficacy and safety of non-pharmacological interventions for patients with dementia. METHODS:We will search ALOIS, the specialized register of the Cochrane Dementia and Cognitive Improvement Group (CDCIG), without ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000017279

    authors: Lee GE,Kim JY,Jung JH,Kang HW,Jung IC

    更新日期:2019-09-01 00:00:00

  • Application effect of lattice laser in facial rejuvenation: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Various techniques have been applied in facial rejuvenation and lattice laser is the most accepted. However, the application effect of lattice laser in facial rejuvenation is unclear. This study aims to evaluate the application effect of lattice laser in facial rejuvenation. METHODS:Randomized controlled tr...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021814

    authors: Yan D,Huang Z,Zhang A,Li S,Xiao Y

    更新日期:2020-08-21 00:00:00

  • Effects of recombinant human brain natriuretic peptide in patients with acute myocardial infarction undergoing percutaneous coronary intervention: A systematic review and meta-analysis.

    abstract:OBJECTIVE:To systematically review the effect of recombinant human brain natriuretic peptide (rhBNP) on the cardiac function in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). METHODS:PubMed, Web of Science, the Cochrane Library, Chinese Biomedical Database (CBD), a...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000019479

    authors: Ning C,Zheng Y,Li J,Liu M,Fang Z

    更新日期:2020-03-01 00:00:00

  • Saturated salt solution method: a useful cadaver embalming for surgical skills training.

    abstract::This article evaluates the suitability of cadavers embalmed by the saturated salt solution (SSS) method for surgical skills training (SST). SST courses using cadavers have been performed to advance a surgeon's techniques without any risk to patients. One important factor for improving SST is the suitability of specime...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000196

    authors: Hayashi S,Homma H,Naito M,Oda J,Nishiyama T,Kawamoto A,Kawata S,Sato N,Fukuhara T,Taguchi H,Mashiko K,Azuhata T,Ito M,Kawai K,Suzuki T,Nishizawa Y,Araki J,Matsuno N,Shirai T,Qu N,Hatayama N,Hirai S,Fukui H,O

    更新日期:2014-12-01 00:00:00

  • Antibiotic prescribing trends in a pediatric population in Lithuania in 2003-2012: Observational study.

    abstract::The purpose of this study was to determine the trends in consumption of antibiotics and evaluate the antibiotic prescription rates in the pediatric population in Lithuania during 2003 to 2012.A cross-sectional study. Data of systemic antibiotic use in pediatric population for outpatient treatment was derived from Nati...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017220

    authors: Karinauske E,Kasciuskeviciute S,Morkuniene V,Garuoliene K,Kadusevicius E

    更新日期:2019-11-01 00:00:00

  • Tissue selecting technique mega-window stapler combined with anal canal epithelial preservation operation for the treatment of severe prolapsed hemorrhoids: A study protocol for a randomized controlled trial.

    abstract:INTRODUCTION:Hemorrhoidal disease is one of the most common and frequently occurring benign anorectal disorders, presented with bleeding and prolapsed, and surgery is the main and effective method for severe prolapsed hemorrhoids. Yet, the recurrence rate after procedure for prolapse and hemorrhoids (PPH) is significan...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023122

    authors: Ji L,Li L,Weng L,Hu Y,Huang H,Wei J

    更新日期:2020-11-06 00:00:00

  • PEAR1 gene polymorphism in a Chinese pedigree with pulmonary thromboembolism.

    abstract::To explore the correlation between platelet endothelial aggregation receptor-1 (PEAR1) genetic polymorphism and pulmonary thromboembolism (PTE).Variant loci of the PEAR1 gene were screened in a PTE pedigree, followed by verification using Sanger sequencing. These polymorphic loci were validated in 101 PTE patients and...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005687

    authors: Fu Y,Sun S,Liang J,Liu S,Jiang Y,Xu L,Mei J

    更新日期:2016-12-01 00:00:00

  • New vertebral fractures after osteoporotic vertebral compression fracture between balloon kyphoplasty and nonsurgical treatment PRISMA.

    abstract:BACKGROUND:Because of aging of population, osteoporotic vertebral compression fracture (OVCF) appears an increasing incidence rate. Conservative therapy (CT) and balloon kyphoplasty (BKP) have been used to treat OVCFs. However, an increase in new vertebral compression fractures at nontreated levels following BKP is of ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000012666

    authors: Li HM,Zhang RJ,Gao H,Jia CY,Zhang JX,Dong FL,Shen CL

    更新日期:2018-10-01 00:00:00

  • Evaluation of intrathecal drug delivery system for intractable pain in advanced malignancies: A prospective cohort study.

    abstract::Pain is prevalent in advanced malignancies; however, some patients cannot get adequate pain relief by conservative routes of analgesic administration or experience serious side effects related to high dose of opioids. For those who have exhausted multimodal conservative analgesic, intrathecal drug delivery is an alter...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006354

    authors: Zheng S,He L,Yang X,Li X,Yang Z

    更新日期:2017-03-01 00:00:00

  • High preoperative C-reactive protein level is a risk factor for acute exacerbation of interstitial lung disease after non-pulmonary surgery.

    abstract::Several studies have investigated the incidence of and risk factors for acute exacerbation (AE) in patients with interstitial lung disease (ILD) after lung resection surgery. However, the incidence and risk factors for AE-ILD after non-pulmonary surgery are not known. The aim of this study was to investigate the incid...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014296

    authors: Takao S,Masuda T,Yamaguchi K,Sakamoto S,Horimasu Y,Nakashima T,Miyamoto S,Iwamoto H,Fujitaka K,Hamada H,Hattori N

    更新日期:2019-02-01 00:00:00

  • Integrase inhibitor-based regimens result in more rapid virologic suppression rates among treatment-naïve human immunodeficiency virus-infected patients compared to non-nucleoside and protease inhibitor-based regimens in a real-world clinical setting: A r

    abstract::The integrase strand transfer inhibitor (INSTI) class of antiretroviral therapy (ART) may result in faster time to virologic suppression compared with regimens that contain protease inhibitors (PIs) or non-nucleoside reverse transcriptase inhibitors (NNRTIs). However, differences in time to achieve virologic suppressi...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013016

    authors: Jacobson K,Ogbuagu O

    更新日期:2018-10-01 00:00:00

  • Protocol of randomized control trial for effectiveness of angiotensin receptor blockers on blood pressure control among euvolemic hypertensive hemodialysis patients.

    abstract:INTRODUCTION:Volume overload and the renin-aldosterone-angiotensin system (RAAS) are 2 major factors contributing to hypertension (HTN) among hemodialysis (HD) patients. Although volume-dependent components of HTN can be corrected by appropriate volume removal, a proportion of HD patients experience elevated blood pres...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000006198

    authors: Aftab RA,Khan AH,Syed Sulaiman SA,Khan TM,Adnan AS

    更新日期:2017-04-01 00:00:00

  • Incidence of dysphagia and dysphonia after Hangman's fractures: Evidence from 93 patients.

    abstract::This research aims to explore the accurate incidence, severity and outcomes of dysphagia and dysphonia after Hangman fractures.A total of 93 patients were included in this study and clinical data were reviewed. The Bazaz grading system (0-None; 1-Mild; 2-Moderate; 3-Severe) was used for dysphagia evaluation and the Vo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013552

    authors: Yang Y,Dai L,Ma L,Gao X,Liu H

    更新日期:2018-12-01 00:00:00

  • McCune Albright syndrome is a genetic predisposition to intraductal papillary and mucinous neoplasms of the pancreas associated pancreatic cancer in relation with GNAS somatic mutation - a case report.

    abstract:RATIONALE:Intraductal papillary and mucinous neoplasms of the pancreas (IPMN) are preneoplastic lesions diagnosed with an increasing incidence. Recently, several groups have described, in up to 70% of IPMN, activating mutations of the G-protein alpha stimulatory sub-unit (Gsα subunit) gene (GNAS). GNAS-activating somat...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018102

    authors: Gaujoux S,Pasmant E,Silve C,Mehsen-Cetre N,Coriat R,Rouquette A,Douset B,Prat F,Leroy K

    更新日期:2019-12-01 00:00:00

  • Comparative effectiveness of different oral antibiotics regimens for treatment of urinary tract infection in outpatients: an analysis of national representative claims database.

    abstract::[An uncorrected version of "Comparative Effectiveness of Different Oral Antibiotics Regimens for Treatment of Urinary Tract Infection in Outpatients: An Analysis of National Representative Claims Database" was originally posted in Volume 93, Issue 28 of Medicine. The article has since been corrected and reposted in th...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/01.md.0000460804.00343.a0

    authors:

    更新日期:2015-01-01 00:00:00

  • Nontraumatic avulsion of aortic valve commissure as a cause of acute aortic valve regurgitation: A case report.

    abstract:BACKGROUND:Avulsion of the aortic valve commissure as a cause of acute aortic valve regurgitation is mostly due to trauma, infective endocarditis, or ascending aortic dissection. Nontraumatic avulsion of the aortic valve commissure is very rare. We reviewed the literature and analyzed potential risk factors of nontraum...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005053

    authors: Chang RY,Chen CC,Hsu WP,Hsiao PC,Tsai HL,Hsiao PG,Wu JD,Guo HR

    更新日期:2016-10-01 00:00:00

  • Case report of tracheobronchial injuries after acid ingestion: CT findings with serial follow-up: Airway complication after acid ingestion.

    abstract:RATIONALE:Tracheobronchial injury from acid ingestion is a less reported clinical presentation than injury of the gastrointestinal tract, but it can occur due to direct exposure from acid aspiration and cause fatal complications. PATIENT CONCERNS:A 43-year-old man presented to the emergency department after ingesting ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023586

    authors: Kim N,Lee HN,Kim JI,Shin SY,Kang SW

    更新日期:2020-12-11 00:00:00