Evaluation of intrathecal drug delivery system for intractable pain in advanced malignancies: A prospective cohort study.

abstract：:We initiated a prospective study with a group of practitioners to assess the etiology, clinical presentation, and outcome of community-acquired pneumonia in patients diagnosed in the outpatient setting. All patients with signs and symptoms suggestive of pneumonia and an infiltrate on chest X-ray underwent an extensive...

journal_title：Medicine

authors： Bochud PY,Moser F,Erard P,Verdon F,Studer JP,Villard G,Cosendai A,Cotting M,Heim F,Tissot J,Strub Y,Pazeller M,Saghafi L,Wenger A,Germann D,Matter L,Bille J,Pfister L,Francioli P

更新日期：2001-03-01 00:00:00

abstract：:To establish the comparative effectiveness of all available biologic therapy regimens for ankylosing spondylitis, we performed a systematic review and a Bayesian network meta-analysis of randomized controlled trials. PubMed, Medline, Embase, Cochrane library, and ClinicalTrials.gov were searched from the inception of ...

journal_title：Medicine

authors： Chen C,Zhang X,Xiao L,Zhang X,Ma X

更新日期：2016-03-01 00:00:00

abstract：:To assess the hypothesis if tocilizumab (TCZ) is effective on disease activity, and also its effect in fatigue and other clinical and psychological disease-related factors in patients with rheumatoid arthritis (RA) treated with TCZ.A 24-week, multicenter, prospective, observational study in patients with moderate to s...

journal_title：Medicine

authors： Corominas H,Alegre C,Narváez J,Fernández-Cid CM,Torrente-Segarra V,Gómez MR,Pan FM,Morlà RM,Martínez FJR,Gómez-Centeno A,Ares LL,Molina RG,González-Albo SP,Dalmau-Carolà J,Pérez-García C,Álvarez CB,Ercole L,Terrancle MÁ

更新日期：2019-06-01 00:00:00

abstract：RATIONALE:In patients with pituitary thyroid hormone resistance, the ability of the pituitary gland to detect (and down-regulate) the increase of triiodothyronine is selectively impaired, while the periphery remains sensitive to triiodothyronine levels, producing symptoms of peripheral thyrotoxicity. Subsequently, ther...

journal_title：Medicine

authors： Yu C,Zhao J,Yao J,Wang H,Shang H,Zhang R,Cui Y,Wang L,Dong J,Liao L

更新日期：2018-05-01 00:00:00

abstract：RATIONALE:Colorectal liver metastasis develops in 50% of patients diagnosed with colorectal cancer, whereas concurrent intrahepatic cholangiocarcinoma (ICC) and colorectal liver metastases is extremely rare. PATIENT CONCERNS:A 72-year-old man was referred to our hospital complaining of abdominal discomfort, diarrhea, ...

journal_title：Medicine

authors： Cheng X,Zhao F,Chen D,Yang P,Zhong W,Xu X,Wang W

更新日期：2018-12-01 00:00:00

abstract：:Breast cancer patients with significant comorbidities present reconstructive challenges due to a predictably high complication rate. During expander-based breast reconstruction, human acellular dermal matrix (ADM) is often used to prevent pectoralis muscle retraction, facilitate early expansion, and improve cosmetic o...

journal_title：Medicine

authors： Wilson HB

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Epithelial ovarian cancer (EOC) has been classified into four molecular subtypes, of which the mesenchymal subtype has the poorest survival. Our goal is to develop an immune-based prognostic signature by incorporating molecular subtypes for EOC patients. METHODS:The gene expression profiles of EOC samples w...

journal_title：Medicine

authors： Sheng M,Tong H,Lu X,Shanshan N,Zhang X,Reddy BA,Shu P

更新日期：2020-10-09 00:00:00

abstract：:The aim of this study was to investigate whether histogram analysis in diffusion-weighted (DW) magnetic resonance imaging (MRI) can help differentiate pancreatic adenocarcinomas from neuroendocrine tumors.Sixty-four patients with histologically confirmed 53 pancreatic adenocarcinomas or 19 neuroendocrine tumors underw...

journal_title：Medicine

authors： Shindo T,Fukukura Y,Umanodan T,Takumi K,Hakamada H,Nakajo M,Umanodan A,Ideue J,Kamimura K,Yoshiura T

更新日期：2016-01-01 00:00:00

abstract：:This study aimed to further understand the role of relative telomere length (RTL) in susceptibility to gastric carcinoma (GC) and investigate the association between genetic polymorphisms in the telomere length related genes and GC risk.RTL was measured using the real-time quantitative polymerase chain reaction from 1...

journal_title：Medicine

authors： Lili M,Yuxiang F,Zhongcheng H,Ying S,Ru C,Rong X,Jiang L

更新日期：2020-06-05 00:00:00

abstract：RATIONALE:Nonocclusive mesenteric ischemia (NOMI) is a life-threatening disorder; prompt diagnosis is vital. Surgical treatment is often required, but some cases can be treated conservatively. We herein report an extremely rare case wherein protein-losing enteropathy (PLE) developed after conservative treatment of NOMI...

journal_title：Medicine

authors： Shima T,Ozeki M,Kinoshita T,Honda K,Inoue H,Morita S

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Anorectal malignant melanoma (AMM) is a rare and aggressive malignance with poor prognosis, yet no consensus of treatment exists to date. Abdominoperineal resection surgery (APR) is the standard treatment of anorectal malignant melanoma, capable of controlling lymphatic spread and obtaining a large negativ...

journal_title：Medicine

authors： Xu X,Ge T,Wang G

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The single nucleotide polymorphism (SNP) rs12885713 of calmodulin 1 gene (CALM1) has been reported to involve in the etiology of osteoarthritis (OA) in several association studies with limited sample size and conflicting results. The purpose of the present systematic review and meta-analysis was to evaluate a...

journal_title：Medicine

authors： Shi J,Gao ST,Lv ZT,Sheng WB,Kang H

更新日期：2018-09-01 00:00:00

abstract：:The surgical treatment of congenital scoliosis under 10 years is difficult as it involves resecting vertebrae. Moreover, patient follow-up after surgery is extremely important because the patient is a child whose growth has not been completed. However, there are very few long-term follow-up studies after surgical trea...

journal_title：Medicine

authors： Yang JH,Chang DG,Suh SW,Kim W,Park J

更新日期：2020-08-07 00:00:00

abstract：ABSTRACT:Colorectal cancer is a heterogeneous disease with multiple epigenetic alterations and different molecular features. The molecular classification is based on 2 major distinct pathways: microsatellite stable pathway and the microsatellite instability pathway. Molecular profiling of colorectal cancer provides imp...

journal_title：Medicine

authors： Popescu RC,Tocia C,Brînzan C,Cozaru GC,Deacu M,Dumitru A,Leopa N,Mitroi AF,Nicolau A,Dumitru E

更新日期：2021-01-08 00:00:00

abstract：RATIONALE:Garden type I femoral neck fractures are incomplete stable fractures with impaction in valgus fractures that the question of whether there exists Garden type I femoral neck fracture is currently uncertain. There is still disagreement on the existence of the Garden type I fractures. PATIENT CONCERNS:Herein we...

journal_title：Medicine

authors： Xian H,Zhang H,Lian K,Lin D

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:We conducted this study to compare the efficacy and safety of entecavir and tenofovir in the treatment of treatment-naïve HBV e antigen (HBeAg)-positive patients with chronic hepatitis B (CHB) for 144 weeks. METHODS:A total of 320 treatment-naïve HBeAg-positive CHB patients who received randomly a single reg...

journal_title：Medicine

authors： Cai D,Pan C,Yu W,Dang S,Li J,Wu S,Jiang N,Wang M,Zhang Z,Lin F,Xin S,Yang Y,Shen B,Ren H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The argument on whether extracorporeal shock-wave therapy (ESWT) and corticosteroid injections (CSIs) exert an equivalent pain control or which is the better treatment for plantar fasciitis (PF) in adults remains to be resolved. It is important and necessary to conduct a meta-analysis to make a relatively mo...

journal_title：Medicine

authors： Li S,Wang K,Sun H,Luo X,Wang P,Fang S,Chen H,Sun X

更新日期：2018-12-01 00:00:00

abstract：:Chemotherapy-induced amenorrhea (CIA) is a side effect that occurs in patients with breast cancer (BC) as a result of chemotherapy. These patients require special treatments to avoid infertility and menopause. However, the factors controlling CIA, resumption of menstruation (RM), and persistence of menstruation after ...

journal_title：Medicine

authors： Jeon SJ,Lee JI,Jeon MJ,Lee M

更新日期：2016-04-01 00:00:00

abstract：:Although the outcome of renal transplantation in patients with systemic lupus erythematosus (SLE) has been studied, there are few reports about the outcome of patients with systemic sclerosis who have undergone renal transplantation. We retrospectively collected data from the United Network for Organ Sharing (UNOS) Sc...

journal_title：Medicine

authors： Chang YJ,Spiera H

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) is a global pandemic caused by the severe acute respiratory syndrome coronavirus-2.COVID-19 is highly pathogenic and infectious. COVID-19 epidemic is still spreading all over the world, and there is no sign of stopping at present. There is no specific cure for this disease...

journal_title：Medicine

authors： Zhou H,Chen D,Zhang Y,Zhu Q,Yang Y,Liu Y,Gong G,Xie C

更新日期：2020-11-13 00:00:00

abstract：:The objective of this study was to assess whether preoperative breast magnetic resonance imaging (MRI) combined with conventional breast imaging techniques decreases the rates of margin involvement and reexcision.Data on patients who underwent surgery for primary operable breast cancer were obtained from the Changhua ...

journal_title：Medicine

authors： Lai HW,Chen CJ,Lin YJ,Chen SL,Wu HK,Wu YT,Kuo SJ,Chen ST,Chen DR

更新日期：2016-05-01 00:00:00

abstract：RATIONALE:Pseudoprogression, that is, initial tumor growth followed by subsequent tumor regression, has been well described for immunomodulation therapy in melanoma patients. This phenomenon is not well defined in lung cancer. Nivolumab, an anti-PD-1 monoclonal antibody, was recently approved for nonsmall cell lung can...

journal_title：Medicine

authors： Sarfaty M,Moore A,Dudnik E,Peled N

更新日期：2017-01-01 00:00:00

abstract：:Lymphoid follicles/aggregates in gastric biopsies have been traditionally linked to Helicobacter pylori gastritis, and less commonly to other inflammatory and neoplastic conditions. The frequency of such aggregates in normal stomachs has yet to be adequately evaluated. This is especially relevant when it comes to diag...

journal_title：Medicine

authors： Chakhachiro Z,Saroufim M,Safadi B,Attieh M,Assaf N,Shamseddine G,Tamim H,Boulos F

更新日期：2020-02-01 00:00:00

abstract：RATIONALE:Primary diffuse large B-cell lymphoma of the chest wall is extremely rare. A majority of the pleural lymphomas develop in patients with chronic tuberculous pyothorax. The underlying mechanism might be attributed to the sustained stimulation of chronic inflammation. Surgery followed by adjuvant chemotherapy ca...

journal_title：Medicine

authors： Zhang Q,Ju Y,Qu T,Wang T,Liu X

更新日期：2018-11-01 00:00:00

abstract：RATIONALE:Primary end-to-end anastomosis is common in adult trachea resection. Nevertheless, considering that the utilization of grafts is still essential for restoring defect in long-segment tracheal resection surgery, long-segment tracheal resection and reconstruction still remain challenging. Herein we present a nov...

journal_title：Medicine

authors： Xie H,Zhang Y,Yu F,Wang X

更新日期：2019-11-01 00:00:00

abstract：:Although step counters are increasingly being used in walking programmes to promote sedentary behavior changes in adults, their effectiveness remains unknown. The aim of this meta-analysis of randomized controlled trials (RCTs) was to assess the effectiveness of step counter use in reducing sedentary time among adults...

journal_title：Medicine

authors： Qiu S,Cai X,Ju C,Sun Z,Yin H,Zügel M,Otto S,Steinacker JM,Schumann U

更新日期：2015-09-01 00:00:00

abstract：INTRODUCTION:Ciliated retroperitoneal foregut cysts are rare, and to obtain a preoperative definitive diagnosis of this condition is relatively difficult. In addition, the exact mechanism and formation of ciliated retroperitoneal foregut cysts remains unknown. CASE PRESENTATION:Here, we report a case of a 47-year-old ...

journal_title：Medicine

authors： Chen HY,Wei SM,Chen JY,Zhu XL,Yu RS

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The incidence of nocturia is high and will seriously affect patients' physical and mental health. Nocturnal polyuria is the most critical cause of nocturia, There are few drugs currently used to treat nocturia due to Nocturnal Polyuria (NP). The guide highly recommends only Desmopressin. There is an urgent n...

journal_title：Medicine

authors： Fan Z,Wang Z,Deng J,Jiang Y

更新日期：2020-12-18 00:00:00

abstract：INTRODUCTION:Chemotherapy-induced peripheral neuropathy (CIPN) occurs in approximately 30% to 40% of patients who receive chemotherapy; however, standardized treatment for CIPN has not yet been developed. Acupuncture is widely used to treat CIPN in Korea, but its efficacy has not been investigated. The purpose of this ...

journal_title：Medicine

authors： Hwang MS,Lee HY,Lee JH,Choi TY,Lee JH,Ko YS,Choi SY,Park TY

更新日期：2019-04-01 00:00:00

abstract：RATIONALE:Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by rapidly progressive hypertension, headache, and disturbance of consciousness. Moreover, RPLS is rarely reported after apatinib treatment. PATIENT CONCERNS:We present a case of RPLS induced by apatinib in this report. The patient had...

journal_title：Medicine

authors： Lv Y,Zhang Y,Zhang J,Liang N,Liu F,Liu R

更新日期：2019-11-01 00:00:00